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Volumn 20, Issue 5, 2006, Pages 769-771

A link between immune hyperactivation of T cells during HIV-1 infection and the virus protease?

Author keywords

CD4 T cell decline; HIV 1 fitness; HIV 1 protease; Protease inhibitors; T cell hyperactivation

Indexed keywords

EDITORIAL; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOREACTIVITY; MEMORY CELL; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; VIREMIA; VIRUS REPLICATION;

EID: 33745087778     PISSN: 02699370     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.aids.0000216378.84313.b6     Document Type: Editorial
Times cited : (4)

References (18)
  • 1
    • 8944258925 scopus 로고    scopus 로고
    • Shortened telomeres in the expanded CD28-CD8+ cell subset in HIV disease implicate replicative senescence in HIV pathogenesis
    • Effros RB, Allsopp R, Chiu CP, Hausner MA, Hirji K, Wang L, et al. Shortened telomeres in the expanded CD28-CD8+ cell subset in HIV disease implicate replicative senescence in HIV pathogenesis. AIDS 1996; 10:F17-F22.
    • (1996) AIDS , vol.10
    • Effros, R.B.1    Allsopp, R.2    Chiu, C.P.3    Hausner, M.A.4    Hirji, K.5    Wang, L.6
  • 2
    • 27944503411 scopus 로고    scopus 로고
    • Loss of IL-7Rα is associated with CD4+ T cell depletion, high IL-7 levels and CD28 down-regulation in HIV infected patients
    • Rethi B, Fluur C, Atlas A, Krzyzowska M, Mowafi F, Grützmeier S, et al. Loss of IL-7Rα is associated with CD4+ T cell depletion, high IL-7 levels and CD28 down-regulation in HIV infected patients. AIDS 2005; 19:2077-2086.
    • (2005) AIDS , vol.19 , pp. 2077-2086
    • Rethi, B.1    Fluur, C.2    Atlas, A.3    Krzyzowska, M.4    Mowafi, F.5    Grützmeier, S.6
  • 4
    • 3843056825 scopus 로고    scopus 로고
    • Immune activation set point during early HIV infection predicts subsequent CD4+ T cell changes indipendent of viral load
    • Deeks SC, Kitchen CMR, Liu L, Guo H, Gascon R, Narväez AB, et al. Immune activation set point during early HIV infection predicts subsequent CD4+ T cell changes indipendent of viral load. Blood 2004; 104:942-947.
    • (2004) Blood , vol.104 , pp. 942-947
    • Deeks, S.C.1    Kitchen, C.M.R.2    Liu, L.3    Guo, H.4    Gascon, R.5    Narväez, A.B.6
  • 5
    • 0038701685 scopus 로고    scopus 로고
    • T cell activation is associated with lower CD4+ T cell gains in human immunodeficiency virus-infected patients with sustained viral suppression during antiretroviral therapy
    • Hunt PW, Martin JN, Sinclair E, Bredt B, Hagos E, Lampiris H, et al. T cell activation is associated with lower CD4+ T cell gains in human immunodeficiency virus-infected patients with sustained viral suppression during antiretroviral therapy. J Infect Dis 2003; 187:1534-1543.
    • (2003) J Infect Dis , vol.187 , pp. 1534-1543
    • Hunt, P.W.1    Martin, J.N.2    Sinclair, E.3    Bredt, B.4    Hagos, E.5    Lampiris, H.6
  • 6
    • 0343920019 scopus 로고    scopus 로고
    • T-cell division in human immunodeficiency virus (HIV)-1 infection is mainly due to immune activation: A longitudinal analysis in patients before and during highly active antiretroviral therapy (HAART)
    • Hazenberg MD, Stuart JWT, Otto SA, Borleffs JCC, Boucher CAB, de Boer RJ, et al. T-cell division in human immunodeficiency virus (HIV)-1 infection is mainly due to immune activation: a longitudinal analysis in patients before and during highly active antiretroviral therapy (HAART). Blood 2000; 95:249-255.
    • (2000) Blood , vol.95 , pp. 249-255
    • Hazenberg, M.D.1    Stuart, J.W.T.2    Otto, S.A.3    Borleffs, J.C.C.4    Boucher, C.A.B.5    De Boer, R.J.6
  • 7
    • 0030868897 scopus 로고    scopus 로고
    • Positive effects of combined antiretroviral therapy on CD4+ T cell homeostasis and function in advanced HIV disease
    • Autran B, Carcelain G, Li TS, Blanc C, Mathez D, Tubiana R, et al. Positive effects of combined antiretroviral therapy on CD4+ T cell homeostasis and function in advanced HIV disease. Science 1997; 277:112-116.
    • (1997) Science , vol.277 , pp. 112-116
    • Autran, B.1    Carcelain, G.2    Li, T.S.3    Blanc, C.4    Mathez, D.5    Tubiana, R.6
  • 8
    • 0034692559 scopus 로고    scopus 로고
    • High plasma levels of soluble Fas in HIV type 1-infected subjects are not normalized during highly active antiretroviral therapy
    • De Milito A, Hejdeman B, Albert J, Aleman S, Sonnerborg A, Zazzi M, et al. High plasma levels of soluble Fas in HIV type 1-infected subjects are not normalized during highly active antiretroviral therapy. AIDS Res Hum Retroviruses 2000; 16:1379-1384.
    • (2000) AIDS Res Hum Retroviruses , vol.16 , pp. 1379-1384
    • De Milito, A.1    Hejdeman, B.2    Albert, J.3    Aleman, S.4    Sonnerborg, A.5    Zazzi, M.6
  • 9
    • 0033831175 scopus 로고    scopus 로고
    • Increased cell division but nor thymic dysfunction rapidly affects the T-cell receptor excision circle content of the naïve T cell population in HIV-1 infection
    • Hazenberg MD, Otto SA, Stuart JWT, Verschuren MCM, Borleffs JCC, Boucher CAB, et al. Increased cell division but nor thymic dysfunction rapidly affects the T-cell receptor excision circle content of the naïve T cell population in HIV-1 infection. Nat Med 2000; 6:1036-1042.
    • (2000) Nat Med , vol.6 , pp. 1036-1042
    • Hazenberg, M.D.1    Otto, S.A.2    Stuart, J.W.T.3    Verschuren, M.C.M.4    Borleffs, J.C.C.5    Boucher, C.A.B.6
  • 10
    • 0034304597 scopus 로고    scopus 로고
    • T cell depletion in HIV-1 infection: How CD4+ T cells go out of stock
    • Hazenberg MD, Hamann D, Schuitemaker H, Miedema F. T cell depletion in HIV-1 infection: how CD4+ T cells go out of stock. Nat Immunol 2000; 1:285-289.
    • (2000) Nat Immunol , vol.1 , pp. 285-289
    • Hazenberg, M.D.1    Hamann, D.2    Schuitemaker, H.3    Miedema, F.4
  • 11
    • 25844482131 scopus 로고    scopus 로고
    • Perils at mucosal front lines for HIV and SIV and their hosts
    • Haase AT. Perils at mucosal front lines for HIV and SIV and their hosts. Nat Rev Immunol 2005; 5:783-792.
    • (2005) Nat Rev Immunol , vol.5 , pp. 783-792
    • Haase, A.T.1
  • 12
    • 0036838224 scopus 로고    scopus 로고
    • Evolution of phenotypic drug susceptibility and viral replication capacity during long-term virologic failure of protease inhibitor therapy in human immunodeficiency virus-infected adults
    • Barbour JD, Wrin T, Grant RM, Martin JN, Segal MR, Petropoulos CJ, et al. Evolution of phenotypic drug susceptibility and viral replication capacity during long-term virologic failure of protease inhibitor therapy in human immunodeficiency virus-infected adults. J Virol 2002; 76:11104-11112.
    • (2002) J Virol , vol.76 , pp. 11104-11112
    • Barbour, J.D.1    Wrin, T.2    Grant, R.M.3    Martin, J.N.4    Segal, M.R.5    Petropoulos, C.J.6
  • 13
    • 3142678466 scopus 로고    scopus 로고
    • Higher CD4+ T cell counts associated with low viral pol replication capacity among treatment-naïve adults in early HIV-1 infection
    • Barbour JD, Hecht FM, Wrin T, Segal MR, Ramstead CA, Liegler TJ, et al. Higher CD4+ T cell counts associated with low viral pol replication capacity among treatment-naïve adults in early HIV-1 infection. J Infect Dis 2004; 190:251-256.
    • (2004) J Infect Dis , vol.190 , pp. 251-256
    • Barbour, J.D.1    Hecht, F.M.2    Wrin, T.3    Segal, M.R.4    Ramstead, C.A.5    Liegler, T.J.6
  • 14
    • 27144549662 scopus 로고    scopus 로고
    • Interruption of treatment with individual therapeutic drug classes in adults with multidrug-resistant HIV-1 infection
    • Deeks SG, Hoh R, Neilands TB, Liegler T, Aweeka F, Petropoulos CJ, et al. Interruption of treatment with individual therapeutic drug classes in adults with multidrug-resistant HIV-1 infection. J Infect Dis 2005; 192:1537-1544.
    • (2005) J Infect Dis , vol.192 , pp. 1537-1544
    • Deeks, S.G.1    Hoh, R.2    Neilands, T.B.3    Liegler, T.4    Aweeka, F.5    Petropoulos, C.J.6
  • 15
    • 19944427724 scopus 로고    scopus 로고
    • Persistent low viral load on antiretroviral therapy is associated with T-cell mediated control of HIV replication
    • Alatrakchi N, Duvivier C, Costagliola D, Samri A, Marcelin AG, Kamkamidze G, et al. Persistent low viral load on antiretroviral therapy is associated with T-cell mediated control of HIV replication. AIDS 2005; 19:25-33.
    • (2005) AIDS , vol.19 , pp. 25-33
    • Alatrakchi, N.1    Duvivier, C.2    Costagliola, D.3    Samri, A.4    Marcelin, A.G.5    Kamkamidze, G.6
  • 16
    • 0038082378 scopus 로고    scopus 로고
    • Infectivity and replication capacity of drug-resistant human immunodeficiency virus type 1 variants isolated during primary infection
    • Simon V, Padte N, Murray D, Vanderhoeven J, Wrin T, Parkin N, et al. Infectivity and replication capacity of drug-resistant human immunodeficiency virus type 1 variants isolated during primary infection. J Virol 2003; 77:7736-7745.
    • (2003) J Virol , vol.77 , pp. 7736-7745
    • Simon, V.1    Padte, N.2    Murray, D.3    Vanderhoeven, J.4    Wrin, T.5    Parkin, N.6
  • 17
    • 27944503534 scopus 로고    scopus 로고
    • The B lymphocyte pool during primary HIV-1 infection and effects of early antiretroviral therapy on humoral immunity
    • Titanji K, Chiodi F, Bellocco R, Schepis D, Osorio L, Tassandin C, et al. The B lymphocyte pool during primary HIV-1 infection and effects of early antiretroviral therapy on humoral immunity. AIDS 2005; 19:1947-1955.
    • (2005) AIDS , vol.19 , pp. 1947-1955
    • Titanji, K.1    Chiodi, F.2    Bellocco, R.3    Schepis, D.4    Osorio, L.5    Tassandin, C.6
  • 18
    • 1542283730 scopus 로고    scopus 로고
    • Mechanisms of hypergammaglobulinemia and impaired antigen-specific humoral immunity in HIV-1 infection
    • De Milito A, Nilsson A, Titanji K, Thorstensson R, Reizenstein E, Narita M, et al. Mechanisms of hypergammaglobulinemia and impaired antigen-specific humoral immunity in HIV-1 infection. Blood 2004; 103:2180-2186.
    • (2004) Blood , vol.103 , pp. 2180-2186
    • De Milito, A.1    Nilsson, A.2    Titanji, K.3    Thorstensson, R.4    Reizenstein, E.5    Narita, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.