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Volumn 19, Issue 1, 2005, Pages 25-33

Persistent low viral load on antiretroviral therapy is associated with T cell-mediated control of HIV replication

Author keywords

HIV T cell responses; IFN gamma ELISpot; Low viral load; Proliferative responses

Indexed keywords

ANTIGEN P24; ANTIRETROVIRUS AGENT; CD4 ANTIGEN; CD8 ANTIGEN; GAG PROTEIN; GAMMA INTERFERON; GLYCOPROTEIN GP 160; RNA DIRECTED DNA POLYMERASE INHIBITOR; VIRUS ANTIGEN; VIRUS RNA;

EID: 19944427724     PISSN: 02699370     EISSN: None     Source Type: Journal    
DOI: 10.1097/00002030-200501030-00003     Document Type: Article
Times cited : (47)

References (45)
  • 1
    • 0032991490 scopus 로고    scopus 로고
    • Determinants of paradoxical CD4 cell reconstitution after protease inhibitor-containing antiretroviral regimen
    • Renaud M, Katlama C, Mallet A, Calvez V, Carcelain G, Tubiana R, et al. Determinants of paradoxical CD4 cell reconstitution after protease inhibitor-containing antiretroviral regimen. Aids 1999, 13:669-676.
    • (1999) Aids , vol.13 , pp. 669-676
    • Renaud, M.1    Katlama, C.2    Mallet, A.3    Calvez, V.4    Carcelain, G.5    Tubiana, R.6
  • 2
    • 0034687071 scopus 로고    scopus 로고
    • Clinical outcome of patients with HIV-1 infection according to immunologic and virologic response after 6 months of highly active antiretroviral therapy
    • Crabar S, Le Moing V, Goujard C, Leport C, Kazatchkine MD, Costagliola D, et al. Clinical outcome of patients with HIV-1 infection according to immunologic and virologic response after 6 months of highly active antiretroviral therapy. Ann Intern Med 2000, 133:401-410.
    • (2000) Ann Intern Med , vol.133 , pp. 401-410
    • Crabar, S.1    Le Moing, V.2    Goujard, C.3    Leport, C.4    Kazatchkine, M.D.5    Costagliola, D.6
  • 3
    • 0037692997 scopus 로고    scopus 로고
    • Changes in viral load in people with virological failure who remain on the same HAART regimen
    • Cozzi-Lepri A, Phillips AN, Miller V, Katlama C, Ledergerber B, Vella S, et al. Changes in viral load in people with virological failure who remain on the same HAART regimen. Antivir Ther 2003, 8:127-136.
    • (2003) Antivir Ther , vol.8 , pp. 127-136
    • Cozzi-Lepri, A.1    Phillips, A.N.2    Miller, V.3    Katlama, C.4    Ledergerber, B.5    Vella, S.6
  • 4
    • 0037083230 scopus 로고    scopus 로고
    • Predictors of long-term increase in CD4(+) cell counts in human immunodeficiency virus-infected patients receiving a protease inhibitor-containing antiretroviral regimen
    • Le Moing VTR, Chene G, et al. Predictors of long-term increase in CD4(+) cell counts in human immunodeficiency virus-infected patients receiving a protease inhibitor-containing antiretroviral regimen. J Infect Dis 2002, 185:471-480.
    • (2002) J Infect Dis , vol.185 , pp. 471-480
    • Le Moing, V.T.R.1    Chene, G.2
  • 5
    • 0042415215 scopus 로고    scopus 로고
    • Antiretroviral therapy. Modeling the time course of CD4 T-lymphocyte counts according to the level of virologic rebound in HIV-1-infected patients on highly active
    • Kousignian IAS, Duval X, Descamps D, Matheron S, Costagliola D. Antiretroviral therapy. Modeling the time course of CD4 T-lymphocyte counts according to the level of virologic rebound in HIV-1-infected patients on highly active. J Acquir Immune Defic Syndr 2003, 34:50-57.
    • (2003) J Acquir Immune Defic Syndr , vol.34 , pp. 50-57
    • Kousignian, I.A.S.1    Duval, X.2    Descamps, D.3    Matheron, S.4    Costagliola, D.5
  • 6
    • 3042740596 scopus 로고    scopus 로고
    • Predictors of trend in CD4 positive T-cell count and mortality among HIV-1-infected individuals with virological failure to all three anti-retroviral drug classes
    • PLATO Collaboration. Predictors of trend in CD4 positive T-cell count and mortality among HIV-1-infected individuals with virological failure to all three anti-retroviral drug classes. Lancet 2004, 364:51-62.
    • (2004) Lancet , vol.364 , pp. 51-62
  • 7
    • 0037013040 scopus 로고    scopus 로고
    • Drug resistance at low viraemia in HIV-1-infected patients with antiretroviral combination therapy
    • Aleman S, Soderbarg K, Visco-Comandini U, Sitbon G, Sonnerborg A. Drug resistance at low viraemia in HIV-1-infected patients with antiretroviral combination therapy. Aids 2002, 16:1039-1044.
    • (2002) Aids , vol.16 , pp. 1039-1044
    • Aleman, S.1    Soderbarg, K.2    Visco-Comandini, U.3    Sitbon, G.4    Sonnerborg, A.5
  • 8
    • 0031753527 scopus 로고    scopus 로고
    • Resistance mutations in protease and reverse transcriptase genes of human immunodeficiency virus type 1 isolates from patients with combination antiretroviral therapy failure
    • Young B, Johnson S, Bahktiari M, Shugarts D, Young RK, Allen M, et al. Resistance mutations in protease and reverse transcriptase genes of human immunodeficiency virus type 1 isolates from patients with combination antiretroviral therapy failure. J Infect Dis 1998, 178:1497-1501.
    • (1998) J Infect Dis , vol.178 , pp. 1497-1501
    • Young, B.1    Johnson, S.2    Bahktiari, M.3    Shugarts, D.4    Young, R.K.5    Allen, M.6
  • 9
    • 3142686772 scopus 로고    scopus 로고
    • The Clinical Implications of Reduced Viral Fitness
    • Barbour JD, Grant RM. The Clinical Implications of Reduced Viral Fitness. Curr Infect Dis Rep 2004, 6:151-158.
    • (2004) Curr Infect Dis Rep , vol.6 , pp. 151-158
    • Barbour, J.D.1    Grant, R.M.2
  • 10
    • 0042431969 scopus 로고    scopus 로고
    • Structured treatment interruption in patients with multidrug-resistant human immunodeficiency virus
    • Lawrence J, Mayers DL, Hullsiek KH, Collins G, Abrams DI, Reisler RB, et al. Structured treatment interruption in patients with multidrug-resistant human immunodeficiency virus. N Engl J Med 2003, 349:837-846.
    • (2003) N Engl J Med , vol.349 , pp. 837-846
    • Lawrence, J.1    Mayers, D.L.2    Hullsiek, K.H.3    Collins, G.4    Abrams, D.I.5    Reisler, R.B.6
  • 11
    • 0035864943 scopus 로고    scopus 로고
    • Virologic and immunologic consequences of discontinuing combination antiretroviral-drug therapy in HIV-infected patients with detectable viremia
    • Decks SG, Wrin T, Liegler T, Hoh R, Hayden M, Barbour JD, et al. Virologic and immunologic consequences of discontinuing combination antiretroviral-drug therapy in HIV-infected patients with detectable viremia. N Engl J Med 2001, 344:472-480.
    • (2001) N Engl J Med , vol.344 , pp. 472-480
    • Decks, S.G.1    Wrin, T.2    Liegler, T.3    Hoh, R.4    Hayden, M.5    Barbour, J.D.6
  • 12
    • 0035341522 scopus 로고    scopus 로고
    • Long-term clinical outcome of human immunodeficiency virus-infected patients with discordant immunologic and virologic responses to a protease inhibitor-containing regimen
    • Piketty C, Weiss L, Thomas F, Mohamed AS, Belec L, Kazatchkine MD. Long-term clinical outcome of human immunodeficiency virus-infected patients with discordant immunologic and virologic responses to a protease inhibitor-containing regimen. J Infect Dis 2001, 183:1328-1335.
    • (2001) J Infect Dis , vol.183 , pp. 1328-1335
    • Piketty, C.1    Weiss, L.2    Thomas, F.3    Mohamed, A.S.4    Belec, L.5    Kazatchkine, M.D.6
  • 13
    • 0344688302 scopus 로고    scopus 로고
    • Clinical and immunologic outcome in patients with human immunodeficiency virus infection, according to virologic efficacy in the year after virus undetectability, during antiretroviral therapy
    • Abgrall S, Duval X, Joly V, Descamps D, Matheron S, Costagliola D. Clinical and immunologic outcome in patients with human immunodeficiency virus infection, according to virologic efficacy in the year after virus undetectability, during antiretroviral therapy. Clin Infect Dis 2003, 37: 1517-1526.
    • (2003) Clin Infect Dis , vol.37 , pp. 1517-1526
    • Abgrall, S.1    Duval, X.2    Joly, V.3    Descamps, D.4    Matheron, S.5    Costagliola, D.6
  • 16
    • 0035862330 scopus 로고    scopus 로고
    • Cellular immune responses and viral diversity in individuals treated during acute and early HIV-1 infection
    • Altfeld M, Rosenberg ES, Shankarappa R, Mukherjee JS, Hecht FM, Eldridge RL, et al. Cellular immune responses and viral diversity in individuals treated during acute and early HIV-1 infection. J Exp Med 2001, 193:169-180.
    • (2001) J Exp Med , vol.193 , pp. 169-180
    • Altfeld, M.1    Rosenberg, E.S.2    Shankarappa, R.3    Mukherjee, J.S.4    Hecht, F.M.5    Eldridge, R.L.6
  • 18
    • 0034724371 scopus 로고    scopus 로고
    • Early highly active antiretroviral therapy for acute HIV-1 infection preserves immune function of CD8+ and CD4+ T lymphocytes
    • Oxenius A, Price DA, Easterbrook PJ, O'Callaghan CA, Kelleher AD, Whelan JA, et al. Early highly active antiretroviral therapy for acute HIV-1 infection preserves immune function of CD8+ and CD4+ T lymphocytes. Proc Natl Acad Sci USA 2000, 97:3382-3387.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 3382-3387
    • Oxenius, A.1    Price, D.A.2    Easterbrook, P.J.3    O'Callaghan, C.A.4    Kelleher, A.D.5    Whelan, J.A.6
  • 19
    • 0030868897 scopus 로고    scopus 로고
    • Positive effects of combined antiretroviral therapy on CD4+ T cell homeostasis and function in advanced HIV disease
    • Autran B, Carcelain C, Li TS, Blanc C, Mathez D, Tubiana R, et al. Positive effects of combined antiretroviral therapy on CD4+ T cell homeostasis and function in advanced HIV disease. Science 1997, 277:112-116.
    • (1997) Science , vol.277 , pp. 112-116
    • Autran, B.1    Carcelain, C.2    Li, T.S.3    Blanc, C.4    Mathez, D.5    Tubiana, R.6
  • 20
    • 17344365057 scopus 로고    scopus 로고
    • Immunologic responses associated with 12 weeks of combination antiretroviral therapy consisting of zidovudine, lamivudine, and ritonavir: Results of AIDS Clinical Trials Group Protocol 315
    • Lederman MM, Connick E, Landay A, Kuritzkes DR, Spritzler J, St. Clair M, et al. Immunologic responses associated with 12 weeks of combination antiretroviral therapy consisting of zidovudine, lamivudine, and ritonavir: results of AIDS Clinical Trials Group Protocol 315. J Infect Dis 1998, 178: 70-79.
    • (1998) J Infect Dis , vol.178 , pp. 70-79
    • Lederman, M.M.1    Connick, E.2    Landay, A.3    Kuritzkes, D.R.4    Spritzler, J.5    St. Clair, M.6
  • 21
    • 0032505665 scopus 로고    scopus 로고
    • Lack of T-cell proliferative response to HIV-1 antigens after 1 year of highly active antiretroviral treatment in early HIV-1 disease
    • Immunology Study Group of Spanish EARTH-1 Study
    • Plana M, Garcia F, Gallart T, Miro JM, Gatell JM. Lack of T-cell proliferative response to HIV-1 antigens after 1 year of highly active antiretroviral treatment in early HIV-1 disease. Immunology Study Group of Spanish EARTH-1 Study. Lancet 1998, 352:1194-1195.
    • (1998) Lancet , vol.352 , pp. 1194-1195
    • Plana, M.1    Garcia, F.2    Gallart, T.3    Miro, J.M.4    Gatell, J.M.5
  • 22
    • 0033024591 scopus 로고    scopus 로고
    • Prolonged suppression of human immunodeficiency virus type 1 (HIV-1) viremia in persons with advanced disease results in enhancement of CD4 T cell reactivity to microbial antigens but not to HIV-1 antigens
    • Rinaldo CR Jr, Liebmann JM, Huang XL, Fan Z, Al-Shboul Q, McMahon DK, et al. Prolonged suppression of human immunodeficiency virus type 1 (HIV-1) viremia in persons with advanced disease results in enhancement of CD4 T cell reactivity to microbial antigens but not to HIV-1 antigens. J Infect Dis 1999, 179:329-336.
    • (1999) J Infect Dis , vol.179 , pp. 329-336
    • Rinaldo Jr., C.R.1    Liebmann, J.M.2    Huang, X.L.3    Fan, Z.4    Al-Shboul, Q.5    McMahon, D.K.6
  • 23
    • 0033051593 scopus 로고    scopus 로고
    • Functional T cell reconstitution and human immunodeficiency virus-1-specific cell-mediated immunity during highly active antiretroviral therapy
    • Pontesilli O, Kerkhof-Garde S, Notermans DW, Foudraine NA, Roos MT, Klein MR, et al. Functional T cell reconstitution and human immunodeficiency virus-1-specific cell-mediated immunity during highly active antiretroviral therapy. J Infect Dis 1999, 180:76-86.
    • (1999) J Infect Dis , vol.180 , pp. 76-86
    • Pontesilli, O.1    Kerkhof-Garde, S.2    Notermans, D.W.3    Foudraine, N.A.4    Roos, M.T.5    Klein, M.R.6
  • 24
    • 0032941595 scopus 로고    scopus 로고
    • HIV-1-specific CD4+ T cells are detectable in most individuals with active HIV-1 infection, but decline with prolonged viral suppression
    • Pitcher CJ, Quittner C, Peterson DM, Connors M, Koup RA, Maino VC, et al. HIV-1-specific CD4+ T cells are detectable in most individuals with active HIV-1 infection, but decline with prolonged viral suppression. Nat Med 1999, 5:518-525.
    • (1999) Nat Med , vol.5 , pp. 518-525
    • Pitcher, C.J.1    Quittner, C.2    Peterson, D.M.3    Connors, M.4    Koup, R.A.5    Maino, V.C.6
  • 25
    • 0006922163 scopus 로고    scopus 로고
    • Decay kinetics of human immunodeficiency virus-specific effector cytotoxic T lymphocytes after combination antiretroviral therapy
    • Ogg GS, Jin X, Bonhoeffer S, Moss P, Nowak MA, Monard S, et al. Decay kinetics of human immunodeficiency virus-specific effector cytotoxic T lymphocytes after combination antiretroviral therapy. J Virol 1999, 73:797-800.
    • (1999) J Virol , vol.73 , pp. 797-800
    • Ogg, G.S.1    Jin, X.2    Bonhoeffer, S.3    Moss, P.4    Nowak, M.A.5    Monard, S.6
  • 26
    • 0034254206 scopus 로고    scopus 로고
    • Dynamics of HIV-specific CD8+ T lymphocytes with changes in viral load
    • The RESTIM and COMET Study Groups
    • Mollet L, Li TS, Samri A, Tournay C, Tubiana R, Calvez V, et al. Dynamics of HIV-specific CD8+ T lymphocytes with changes in viral load. The RESTIM and COMET Study Groups. J Immunol 2000, 165:1692-1704.
    • (2000) J Immunol , vol.165 , pp. 1692-1704
    • Mollet, L.1    Li, T.S.2    Samri, A.3    Tournay, C.4    Tubiana, R.5    Calvez, V.6
  • 28
    • 0032719664 scopus 로고    scopus 로고
    • HIV-1-specific immune responses in subjects who temporarily contain virus replication after discontinuation of highly active antiretroviral therapy
    • Ortiz GM, Nixon DF, Trkola A, Binley J, Jin X, Bonhoeffer S, et al. HIV-1-specific immune responses in subjects who temporarily contain virus replication after discontinuation of highly active antiretroviral therapy. J Clin Invest 1999, 104:R13-R18.
    • (1999) J Clin Invest , vol.104
    • Ortiz, G.M.1    Nixon, D.F.2    Trkola, A.3    Binley, J.4    Jin, X.5    Bonhoeffer, S.6
  • 29
    • 0034749278 scopus 로고    scopus 로고
    • Transient mobilization of human immunodeficiency virus (HIV)-specific CD4 T-helper cells fails to control virus rebounds during intermittent antiretroviral therapy in chronic HIV type 1 infection
    • Carcelain C, Tubiana R, Samri A, Calvez V, Delaugerre C, Agut H, et al. Transient mobilization of human immunodeficiency virus (HIV)-specific CD4 T-helper cells fails to control virus rebounds during intermittent antiretroviral therapy in chronic HIV type 1 infection. J Virol 2001, 75:234-241.
    • (2001) J Virol , vol.75 , pp. 234-241
    • Carcelain, C.1    Tubiana, R.2    Samri, A.3    Calvez, V.4    Delaugerre, C.5    Agut, H.6
  • 30
    • 0035875860 scopus 로고    scopus 로고
    • HIV dynamics and T-cell immunity after three structured treatment interruptions in chronic HIV-1 infection
    • Ruiz L, Carcelain G, Martinez-Picado J, Frost S, Marfil S, Paredes R, et al. HIV dynamics and T-cell immunity after three structured treatment interruptions in chronic HIV-1 infection. Aids 2001, 15:F19-F27.
    • (2001) Aids , vol.15
    • Ruiz, L.1    Carcelain, G.2    Martinez-Picado, J.3    Frost, S.4    Marfil, S.5    Paredes, R.6
  • 31
    • 0037108925 scopus 로고    scopus 로고
    • Stimulation of HIV-specific cellular immunity by structured treatment interruption fails to enhance viral control in chronic HIV infection
    • Oxenius A, Price DA, Gunthard HF, Dawson SJ, Fagard C, Perrin L, et al. Stimulation of HIV-specific cellular immunity by structured treatment interruption fails to enhance viral control in chronic HIV infection. Proc Natl Acad Sci U S A 2002, 99:13747-13752.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 13747-13752
    • Oxenius, A.1    Price, D.A.2    Gunthard, H.F.3    Dawson, S.J.4    Fagard, C.5    Perrin, L.6
  • 32
    • 9144231780 scopus 로고    scopus 로고
    • Strong cell-mediated immune responses are associated with the maintenance of low-level viremia in antiretroviral-treated individuals with drug-resistant human immunodeficiency virus type 1
    • Deeks SG, Martin JN, Sinclair E, Harris J, Neilands TB, Maecker HT, et al. Strong cell-mediated immune responses are associated with the maintenance of low-level viremia in antiretroviral-treated individuals with drug-resistant human immunodeficiency virus type 1. J Infect Dis 2004, 189:312-321.
    • (2004) J Infect Dis , vol.189 , pp. 312-321
    • Deeks, S.G.1    Martin, J.N.2    Sinclair, E.3    Harris, J.4    Neilands, T.B.5    Maecker, H.T.6
  • 33
    • 0345701518 scopus 로고    scopus 로고
    • Prolonged CD4+ cell/virus load discordance during treatment with protease inhibitor-based highly active antiretroviral therapy: Immune response and viral control
    • Sufka SA, Ferrari G, Gryszowka VE, Wrin T, Fiscus SA, Tomaras GD, et al. Prolonged CD4+ cell/virus load discordance during treatment with protease inhibitor-based highly active antiretroviral therapy: immune response and viral control. J Infect Dis 2003, 187:1027-1037.
    • (2003) J Infect Dis , vol.187 , pp. 1027-1037
    • Sufka, S.A.1    Ferrari, G.2    Gryszowka, V.E.3    Wrin, T.4    Fiscus, S.A.5    Tomaras, G.D.6
  • 34
    • 0032805881 scopus 로고    scopus 로고
    • Association between virus-specific cytotoxic T-lymphocyte and helper responses in human immunodeficiency virus type 1 infection
    • Kalams SA, Buchbinder SP, Rosenberg ES, Billingsley JM, Colbert DS, Jones NG, et al. Association between virus-specific cytotoxic T-lymphocyte and helper responses in human immunodeficiency virus type 1 infection. J Virol 1999, 73:6715-6720.
    • (1999) J Virol , vol.73 , pp. 6715-6720
    • Kalams, S.A.1    Buchbinder, S.P.2    Rosenberg, E.S.3    Billingsley, J.M.4    Colbert, D.S.5    Jones, N.G.6
  • 35
    • 16044373004 scopus 로고    scopus 로고
    • Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene
    • Samson M, Libert F, Doranz BJ, Rucker J, Liesnard C, Farber CM, et al. Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene. Nature 1996, 382:722-725.
    • (1996) Nature , vol.382 , pp. 722-725
    • Samson, M.1    Libert, F.2    Doranz, B.J.3    Rucker, J.4    Liesnard, C.5    Farber, C.M.6
  • 36
    • 0032950189 scopus 로고    scopus 로고
    • Combined genotypes of CCR5, CCR2, SDF1, and HLA genes can predict the long-term nonprogressor status in human immunodeficiency virus-1-infected individuals
    • Magierowska M, Theodorou I, Debre P, Sanson F, Autran B, Riviere Y, et al. Combined genotypes of CCR5, CCR2, SDF1, and HLA genes can predict the long-term nonprogressor status in human immunodeficiency virus-1-infected individuals. Blood 1999, 93:936-941.
    • (1999) Blood , vol.93 , pp. 936-941
    • Magierowska, M.1    Theodorou, I.2    Debre, P.3    Sanson, F.4    Autran, B.5    Riviere, Y.6
  • 37
    • 0034279805 scopus 로고    scopus 로고
    • An antigenic threshold for maintaining human immunodeficiency virus type 1-specific cytotoxic T lymphocytes
    • Jin X, Ogg G, Bonhoeffer S, Safrit J, Vesanen M, Bauer D, et al. An antigenic threshold for maintaining human immunodeficiency virus type 1-specific cytotoxic T lymphocytes. Mol Med 2000, 6:803-809.
    • (2000) Mol Med , vol.6 , pp. 803-809
    • Jin, X.1    Ogg, G.2    Bonhoeffer, S.3    Safrit, J.4    Vesanen, M.5    Bauer, D.6
  • 38
    • 17444435761 scopus 로고    scopus 로고
    • Cellular cytotoxic response induced by DNA vaccination in HIV-1-infected patients
    • Calarota S, Bratt G, Nordlund S, Hinkula J, Leandersson AC, Sandstrom E, et al. Cellular cytotoxic response induced by DNA vaccination in HIV-1-infected patients. Lancet 1998, 351:1320-1325.
    • (1998) Lancet , vol.351 , pp. 1320-1325
    • Calarota, S.1    Bratt, G.2    Nordlund, S.3    Hinkula, J.4    Leandersson, A.C.5    Sandstrom, E.6
  • 40
    • 0036171258 scopus 로고    scopus 로고
    • Magnitude of functional CD8+ T-cell responses to the gag protein of human immunodeficiency virus type 1 correlates inversely with viral load in plasma
    • Edwards BH, Bansal A, Sabbaj S, Bakari J, Mulligan MJ, Goepfert PA. Magnitude of functional CD8+ T-cell responses to the gag protein of human immunodeficiency virus type 1 correlates inversely with viral load in plasma. J Virol 2002, 76:2298-2305.
    • (2002) J Virol , vol.76 , pp. 2298-2305
    • Edwards, B.H.1    Bansal, A.2    Sabbaj, S.3    Bakari, J.4    Mulligan, M.J.5    Goepfert, P.A.6
  • 42
    • 0033807826 scopus 로고    scopus 로고
    • Immunogenicity of mutations induced by nucleoside reverse transcriptase inhibitors for human immunodeficiency virus type 1-specific cytotoxic T cells
    • Samri A, Haas G, Duntze J, Bouley JM, Calvez V, Katlama C, et al. Immunogenicity of mutations induced by nucleoside reverse transcriptase inhibitors for human immunodeficiency virus type 1-specific cytotoxic T cells. J Virol 2000, 74:9306-9312.
    • (2000) J Virol , vol.74 , pp. 9306-9312
    • Samri, A.1    Haas, G.2    Duntze, J.3    Bouley, J.M.4    Calvez, V.5    Katlama, C.6
  • 43
    • 0347911962 scopus 로고    scopus 로고
    • HlV-1 viremia prevents the establishment of interleukin 2-producing HIV-specific memory CD4+ T cells endowed with proliferative capacity
    • Younes SA, Yassine-Diab B, Dumont AR, Boulassel MR, Grossman Z, Routy JP, et al. HlV-1 viremia prevents the establishment of interleukin 2-producing HIV-specific memory CD4+ T cells endowed with proliferative capacity. J Exp Med 2003, 198:1909-1922.
    • (2003) J Exp Med , vol.198 , pp. 1909-1922
    • Younes, S.A.1    Yassine-Diab, B.2    Dumont, A.R.3    Boulassel, M.R.4    Grossman, Z.5    Routy, J.P.6
  • 44
    • 1642500367 scopus 로고    scopus 로고
    • Skewed representation of functionally distinct populations of virus-specific CD4 T cells in HIV-1-infected subjects with progressive disease: Changes after antiretroviral therapy
    • Harari A, Petitpierre S, Vallelian F, Pantaleo G. Skewed representation of functionally distinct populations of virus-specific CD4 T cells in HIV-1-infected subjects with progressive disease: changes after antiretroviral therapy. Blood 2004, 103:966-972.
    • (2004) Blood , vol.103 , pp. 966-972
    • Harari, A.1    Petitpierre, S.2    Vallelian, F.3    Pantaleo, G.4
  • 45
    • 0033390334 scopus 로고    scopus 로고
    • Clinical and immunologic response without decrease in virus load in patients with AIDS after 24 months of highly active antiretroviral therapy
    • Mezzaroma I, Carlesimo M, Pinter E, Muratori DS, Di Sora F, Chiarotti F, at al. Clinical and immunologic response without decrease in virus load in patients with AIDS after 24 months of highly active antiretroviral therapy. Clin Infect Dis 1999, 29:1423-1430.
    • (1999) Clin Infect Dis , vol.29 , pp. 1423-1430
    • Mezzaroma, I.1    Carlesimo, M.2    Pinter, E.3    Muratori, D.S.4    Di Sora, F.5    Chiarotti, F.6


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