Effects of altered nitric oxide availability on rat muscle microvascular oxygenation during contractions

Acta Physiologica

Volumn 186, Issue 3, 2006, Pages 223-232

  Ferreira, L F ^a   Padilla, D J ^a   Williams, J ^a   Hageman, K S ^a   Musch, T I ^a   Poole, D C ^a  

^a KANSAS STATE UNIVERSITY   (United States)

Author keywords

Blood myocyte oxygen exchange; Exercise hyperaemia; L nitro arginine methyl ester; Oxygen delivery; Sodium nitroprusside; Spinotrapezius muscle

Indexed keywords

N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITROPRUSSIDE SODIUM; OXYGEN;

AGING; ANIMAL TISSUE; ARTICLE; BODY MASS; CHRONIC DISEASE; CHRONOLOGY; COMPARATIVE STUDY; CONTROLLED STUDY; FEMALE; HYPOTHESIS; KINETICS; MEAN ARTERIAL PRESSURE; MICROVASCULATURE; MUSCLE BLOOD VESSEL; MUSCLE CONTRACTION; NONHUMAN; OXYGEN TENSION; OXYGENATION; PHOSPHORESCENCE; PRIORITY JOURNAL; RAT; REST; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; STEADY STATE; TRAPEZIUS MUSCLE;

ANIMALS; BLOOD PRESSURE; ELECTRIC STIMULATION; FEMALE; MUSCLE CONTRACTION; MUSCLE, SKELETAL; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITROPRUSSIDE; OXYGEN; OXYGEN CONSUMPTION; PARTIAL PRESSURE; RATS; RATS, SPRAGUE-DAWLEY; VASODILATOR AGENTS;

EID: 33745067293     PISSN: 17481708     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1748-1716.2006.01523.x     Document Type: Article

References (67)

1. Adams V. Spate U. Krankel N. et al. 2003. Nuclear factor-kappa B activation in skeletal muscle of patients with chronic heart failure: correlation with the expression of inducible nitric oxide synthase. Eur J Cardiovasc Prev Rehabil 10, 273 277.
2. Bagi Z. Koller A. 2003. Lack of nitric oxide mediation of flow-dependent arteriolar dilation in type I diabetes is restored by sepiapterin. J Vasc Res 40, 47 57.
3. Bangsbo J. Krustrup P. Gonzalez-Alonso J. Boushel R. Saltin B. 2000. Muscle oxygen kinetics at onset of intense dynamic exercise in humans. Am J Physiol 279, R899 R906.
4. Behnke B. Kindig C. Musch T. Koga S. Poole D. 2001. Dynamics of microvascular oxygen pressure across the rest-exercise transition in rat skeletal muscle. Respir Physiol 126, 53 63.
5. Behnke B. Barstow T. Kindig C. McDonough P. Musch T. Poole D. 2002a. Dynamics of oxygen uptake following exercise onset in rat skeletal muscle. Respir Physiolo Neurobiol 133, 229 239.
6. Behnke B. Kindig C. McDonough P. Poole D. Sexton W. 2002b. Dynamics of microvascular oxygen pressure during rest-contraction transition in skeletal muscle of diabetic rats. Am J Physiol 283, H926 H932.
7. Behnke B. McDonough P. Padilla D. Musch T. Poole D. 2003. Oxygen exchange profile in rat muscles of contrasting fibre types. J Physiol 549, 597 605.
8. Behnke B. Delp M. Dougherty P. Musch T. Poole D. 2005. Effects of aging on microvascular oxygen pressures in rat skeletal muscle. Respir Physiol Neurobiol 146, 259 268.
9. Bell C. Paterson D. Kowalchuk J. Cunningham D. 1999. Oxygen uptake kinetics of older humans are slowed with age but are unaffected by hyperoxia. Exp Physiol 84, 747 759.
10. Bojunga J. Dresar-Mayert B. Usadel K. Kusterer K. Zeuzem S. 2004. Antioxidative treatment reverses imbalances of nitric oxide synthase isoform expression and attenuates tissue-cGMP activation in diabetic rats. Biochem Biophys Res Commun 316, 771 780.
11. Brown G. 2000. Nitric oxide as a competitive inhibitor of oxygen consumption in the mitochondrial respiratory chain. Acta Physiol Scand 168, 667 674.
12. Burnley M. Doust J.H. Ball D. Jones A.M. 2002. Effects of prior heavy exercise on o2 kinetics during heavy exercise are related to changes in muscle activity. J Appl Physiol 93, 167 174.
13. De Vriese A. Verbeuren T. Van de Voorde J. Lameire N. Vanhoutte P.M. 2000. Endothelial dysfunction in diabetes. Br J Pharmacol 130, 963 974.
14. DeLorey D. Kowalchuk J. Paterson D. 2003. Relationship between pulmonary O2 uptake kinetics and muscle deoxygenation during moderate-intensity exercise. J Appl Physiol 95, 113 120.
15. Didion S. Mayhan W. 1997. Effect of chronic myocardial infarction on in vivo reactivity of skeletal muscle arterioles. Am J Physiol 272, H2403 H2408.
16. Diederich E. Behnke B. McDonough P. et al. 2002. Dynamics of microvascular oxygen partial pressure in contracting skeletal muscle of rats with chronic heart failure. Cardiovasc Res 56, 479 486.
17. Dobson J. Gladden L. 2003. Effect of rhythmic tetanic skeletal muscle contractions on peak muscle perfusion. J Appl Physiol 94, 11 19.
18. Drexler H. Hayoz D. Munzel T. et al. 1992. Endothelial function in chronic congestive heart failure. Am J Cardiol 69, 1596 1601.
19. Ferreira L. Poole D. Barstow T. 2005. Muscle blood flow-O2 uptake interaction and their relation to on-exercise dynamics of O2 exchange. Respir Physiol Neurobiol 147, 91 103.
20. Geer C. Behnke B. McDonough P. Poole D. 2002. Dynamics of microvascular oxygen pressure in the rat diaphragm. J Appl Physiol 93, 227 232.
21. Gielen S. Adams V. Linke A. et al. 2005. Exercise training in chronic heart failure: correlation between reduced local inflammation and improved oxidative capacity in the skeletal muscle. Eur J Cardiovasc Prev Rehabil 12, 393 400.
22. Grassi B. Poole D. Richardson R. Knight D. Erickson B. Wagner P. 1996. Muscle O2 uptake kinetics in humans: implications for metabolic control. J Appl Physiol 80, 988 998.
23. Grassi B. Hogan M. Greenhaff L. et al. 2002. Oxygen uptake on-kinetics in dog gastrocnemius in situ following activation of pyruvate dehydrogenase by dichloroacetate. J Physiol 538, 195 207.
24. Grassi B. Pogliaghi S. Rampichini S. et al. 2003. Muscle oxygenation and pulmonary gas exchange kinetics during cycling exercise on-transients in humans. J Appl Physiol 95, 149 158.
25. Grassi B. Hogan M. Kelley K. Howlett R. Gladden B. 2005. Effects of NOS inhibition by l-NAME on oxygen uptake kinetics in isolated canine muscle in situ. J Physiol 568, 1021 1033.
26. Hamann J. Valic Z. Buckwalter J. Clifford P. 2003. Muscle pump does not enhance blood flow in exercising skeletal muscle. J Appl Physiol 94, 6 10.
27. Hambrecht R. Adams V. Gielen S. et al. 1999. Exercise intolerance in patients with chronic heart failure and increased expression of inducible nitric oxide synthase in the skeletal muscle. J Am Coll Cardiol 33, 174 179.
28. Hepple R. Liu P. Plyley M. Goodman J. 1999. Oxygen uptake kinetics during exercise in chronic heart failure: influence of peripheral vascular reserve. Clin Sci (London) 97, 569 577.
29. Hirai T. Musch T.I. Morgan D.A. et al. 1995a. Differential sympathetic responses to nitric oxide inhibition in anesthetized rats. Am J Physiol 269, R807 R813
30. Musch T. 1995b. Effects of nitric oxide synthase inhibition on the muscle blood flow response to exercise in rats with heart failure. Cardiovasc Res 30, 469 476.
31. Hogan M. Arthur P. Bebout D. Hochachka P. Wagner P. 1992. Role of O2 in regulating tissue respiration in dog muscle working in situ. J Appl Physiol 73, 728 736.
32. Jones A. Wilkerson D. Koppo K. Wilmshurst S. Campbell I. 2003. Inhibition of nitric oxide synthase by l-NAME speeds phase II pulmonary o2 kinetics in the transition to moderate-intensity exercise in man. J Physiol 552, 265 272.
33. Jones A. Wilkerson D. Wilmshurst S. Campbell I. 2004. Influence of l-NAME on pulmonary O2 uptake kinetics during heavy-intensity cycle exercise. J Appl Physiol 96, 1033 1038.
34. Joyner M. Dietz N. 1997. Nitric oxide and vasodilation in human limbs. J Appl Physiol 83, 1785 1796.
35. Kindig C. Gallatin L. Erickson H. Fedde M. Poole D. 2000. Cardiorespiratory impact of the nitric oxide synthase inhibitor l-NAME in the exercising horse. Respir Physiol 120, 151 166.
36. Kindig C. McDonough P. Erickson H. Poole D. 2001. Effect of l-NAME on oxygen uptake kinetics during heavy-intensity exercise in the horse. J Appl Physiol 91, 891 896.
37. Kindig C. McDonough P. Erickson H. Poole D. 2002a. Nitric oxide synthase inhibition speeds oxygen uptake kinetics in horses during moderate domain running. Respir Physiol Neurobiol 132, 169 178.
38. Kindig C. Richardson T. Poole D. 2002b. Skeletal muscle capillary hemodynamics from rest to contractions: implications for oxygen transfer. J Appl Physiol 92, 2513 2520.
39. Koga S. Poole D. Shiojiri T. et al. 2005. Comparison of oxygen uptake kinetics during knee extension and cycle exercise. Am J Physiol 288, R212 R220.
40. Lahiri S. Rumsey W. Wilson D. Iturriaga R. 1993. Contribution of in vivo microvascular Po2 in the cat carotid body chemotransduction. J Appl Physiol 75, 1035 1043.
41. Lo L. Vinogradov S. Koch C. Wilson DF. 1997. A new, water soluble, phosphor for oxygen measurements in vivo. Adv Exp Med Biol 428, 651 656.
42. MacDonald M. Shoemaker J. Tschakovsky M. Hughson R. 1998. Alveolar oxygen uptake and femoral artery blood flow dynamics in upright and supine leg exercise in humans. J Appl Physiol 85, 1622 1628.
43. McDonough P. Behnke B. Padilla D. Musch T. Poole D. 2005. Control of microvascular oxygen pressures in rat muscles comprised of different fibre types. J Physiol 563, 903 913.
44. Meakins J. Long C. 1927. Oxygen consumption, oxygen debt and lactic acid in circulatory failure. J Clin Invest 4, 273 293.
45. Naik J. Valic Z. Buckwalter J. Clifford P. 1999. Rapid vasodilation in response to a brief tetanic contraction. J Appl Physiol 87, 1741 1746.
46. Nishikawa Y. Stepp D. Chilian W. 2000. Nitric oxide exerts feedback inhibition on EDHF-induced coronary arteriolar dilation in vivo. Am J Physiol 279, H459 H465.
47. Pawlowski M. Wilson D. 1992. Monitoring of the oxygen pressure in the blood of live animals using the oxygen dependent quenching of phosphorescence. Adv Exp Med Biol 316, 179 185.
48. Poole D. Wagner P. Wilson DF. 1995. Diaphragm microvascular plasma Po2 measured in vivo. J Appl Physiol 79, 2050 2057.
49. Poole D. Behnke B. McDonough P. McAllister R. Wilson DF. 2004. Measurement of muscle microvascular oxygen pressures: compartmentalization of phosphorescent probe. Microcirculation 11, 317 326.
50. Radegran G. Saltin B. 1999. Nitric oxide in the regulation of vasomotor tone in human skeletal muscle. Am J Physiol 276, H1951 H1960.
51. Regensteiner J. Bauer T. Reusch J. et al. 1998. Abnormal oxygen uptake kinetic responses in women with type II diabetes mellitus. J Appl Physiol 85, 310 317.
52. Riley M. Porszasz J. Stanford C. Nicholls D. 1994. Gas exchange responses to constant work rate exercise in chronic cardiac failure. Br Heart J 72, 150 155.
53. Rumsey W. Vanderkooi J. Wilson D.F. 1988. Imaging of phosphorescence: a novel method for measuring oxygen distribution in perfused tissue. Science 241, 1649 1651.
54. Scheuermann B. Bell C. Paterson D. Barstow T. Kowalchuk J. 2002. Oxygen uptake kinetics for moderate exercise are speeded in older humans by prior heavy exercise. J Appl Physiol 92, 609 616.
55. Segal S. 2000. Integration of blood flow control to skeletal muscle: key role of feed arteries. Acta Physiol Scand 168, 511 518.
56. Shen W. Xu X. Ochoa M. Zhao G. Wolin M. Hintze T. 1994. Role of nitric oxide in the regulation of oxygen consumption in conscious dogs. Circ Res 75, 1086 1095.
57. Sheriff D. Hakeman A. 2001. Role of speed vs. grade in relation to muscle pump function at locomotion onset. J Appl Physiol 91, 269 276.
58. Shoemaker J. Hughson R. 1999. Adaptation of blood flow during the rest to work transition in humans. Med Sci Sports Exerc 31, 1019 1026.
59. Taddei S. Virdis A. Mattei P. et al. 1995. Aging and endothelial function in normotensive subjects and patients with essential hypertension. Circulation 91, 1981 1987.
60. Tanabe T. Maeda S. Miyauchi T. et al. 2003. Exercise training improves ageing-induced decrease in eNOS expression of the aorta. Acta Physiol Scand 178, 3 10.
61. Thomas G. Victor R. 1998. Nitric oxide mediates contraction-induced attenuation of sympathetic vasoconstriction in rat skeletal muscle. J Physiol 506, 817 826.
62. Tschakovsky M. Sheriff D. 2004. Immediate exercise hyperemia: contributions of the muscle pump vs. rapid vasodilation. J Appl Physiol 97, 739 747.
63. Varin R. Mulder P. Richard V. et al. 1999 Exercise improves flow-mediated vasodilation of skeletal muscle arteries in rats with chronic heart failure. Circulation 99, 2951 2957.
64. Vinogradov S. Fernandez-Seara M. Dupan B. Wilson D. 2002. A method for measuring oxygen distributions in tissue using frequency domain phosphorometry. Comp Biochem Physiol A 132, 147 152.
65. Wagner P.D. 1996. Determinants of maximal oxygen transport and utilization. Annu Rev Physiol 58, 21 50.
66. Wilson D. Erecinska M. Drown C. Silver I. 1977. Effect of oxygen tension on cellular energetics. Am J Physiol 233, C135 C140.
67. Woodman C. Price E. Laughlin M. 2002. Aging induces muscle-specific impairment of endothelium-dependent dilation in skeletal muscle feed arteries. J Appl Physiol 93, 1685 1690.