The 2.15 Å crystal structure of Mycobacterium tuberculosis chorismate mutase reveals an unexpected gene duplication and suggests a role in host-pathogen interactions

Biochemistry

Volumn 45, Issue 23, 2006, Pages 6997-7005

  Qamra, Rohini ^a   Prakash, Prachee ^b   Aruna, Bandi ^b   Hasnain, Seyed E ^b,c,d   Mande, Shekhar C ^b  

^a UNIVERSITY OF DELHI   (India)

^b CENTRE FOR DNA FINGERPRINTING AND DIAGNOSTICS   (India)

^c JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH   (India)

^d UNIVERSITY OF HYDERABAD   (India)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA; CELLS; CRYSTAL STRUCTURE; GENES; GENETIC ENGINEERING; PATHOLOGY;

BIOSYNTHETIC PATHWAY; CHORISMATE MUTASE; EXTRACELLULAR MEDIUM; HOST-PATHOGEN INTERACTIONS;

ENZYMES;

AROMATIC AMINO ACID; CHORISMATE MUTASE; PHENYLALANINE; TRYPTOPHAN; TYROSINE;

ARTICLE; CRYSTAL STRUCTURE; CYTOPLASM; ENZYME INHIBITION; ENZYME RELEASE; ENZYME STRUCTURE; GENE DUPLICATION; HOST PATHOGEN INTERACTION; LIGAND BINDING; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; AMINO ACID SEQUENCE; BACTERIAL GENE; CHEMICAL STRUCTURE; CHEMISTRY; ENZYMOLOGY; GENETICS; MOLECULAR GENETICS; PATHOGENICITY; SEQUENCE HOMOLOGY; X RAY CRYSTALLOGRAPHY;

ESCHERICHIA COLI; MYCOBACTERIUM TUBERCULOSIS; SACCHAROMYCES CEREVISIAE;

AMINO ACID SEQUENCE; CHORISMATE MUTASE; CRYSTALLOGRAPHY, X-RAY; GENE DUPLICATION; GENES, BACTERIAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; MYCOBACTERIUM TUBERCULOSIS; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 33745029514     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0606445     Document Type: Article

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