Crystal structure of the T state of allosteric yeast chorismate mutase and comparison with the R State

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 8, 1996, Pages 3330-3334

  Sträter, Norbert ^a   Håkansson, Kjell ^a,c   Schnappauf, Georg ^b   Braus, Gerhard ^b   Lipscomb, William N ^a  

^a HARVARD UNIVERSITY   (United States)

^b UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^c UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

allosteric enzyme; conformational change; enzyme regulation; heterotropic effector; x ray diffraction

Indexed keywords

ARGININE; CHORISMATE MUTASE; GLYCINE; SERINE; THREONINE; TRYPTOPHAN; TYROSINE;

ALLOSTERISM; ARTICLE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME REGULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; SACCHAROMYCES CEREVISIAE; X RAY DIFFRACTION; YEAST;

ALLOSTERIC SITE; BINDING SITES; CHORISMATE MUTASE; CRYSTALLIZATION; MODELS, MOLECULAR; MOLECULAR STRUCTURE; POINT MUTATION; PROTEIN CONFORMATION; SACCHAROMYCES CEREVISIAE;

EID: 0029867028     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.8.3330     Document Type: Article

References (22)

1. Weiss, U. & Edwards, J. M. (1980) The Biosynthesis of Aromatic Amino Compounds (Wiley, New York).
2. Braus, G. H. (1991) Microbiol. Rev. 55, 349-370.
3. Sogo, S. G., Widlanski, T. S., Hoare, J. H., Grimshaw, C. E., Berchthold, G. A. & Knowles, J. R. (1984) J. Am. Chem. Soc. 106, 2701-2703.
4. Copley, S. D. & Knowles, J. R. (1985) J. Am. Chem. Soc. 107, 5306-5308.
5. Hilvert, D., Carpenter, S. H., Nared, K. D. & Auditor, M.-T. M. (1988) Proc. Natl. Acad. Sci. USA 85, 4953-4955.
6. Jackson, D. Y., Jacobs, J. W., Sugaswara, R., Reich, S. H., Bartlett, P. A. & Schultz, P. G. (1988) J. Am. Chem. Soc. 119, 4841-4842.
7. Chook, Y. M., Gray, J. V., Ke, H. & Lipscomb, W. N. (1994) J. Mol. Biol. 240, 476-500.
8. Gray, J. V. & Knowles, J. R. (1994) Biochemistry 33, 9953-9959.
9. Xue, Y., Lipscomb, W. N., Gray, R., Schnappauf, G. & Braus, G. (1994) Proc. Natl. Acad. Sci. USA 91, 10814-10818.
10. Lee, A. Y., Karplus, P. A., Ganem, B. & Clardy, J. (1995) J. Am. Chem. Soc. 117, 3627-3628.
11. Lee, A. Y., Stewart, J. D., Clardy, J. & Ganem, B. (1995) Curr. Biol. 2, 196-203.
12. Xue, Y. & Lipscomb, W. N. (1995) Proc. Natl Acad. Sci. USA 92, 10595-10598.
13. Schmidhcini, T., Mosch, H.-U., Evans, J. N. S. & Braus, G. (1990) Biochemistry 29, 3660-3668.
14. Kabsch, W. (1988) J. Appl. Crystallogr. 21, 916-924.
15. Navaza, J. (1994) Acta Crystallogr. A 50, 157-163.
16. Brünger, A. T. (1992) X-PLOR Manual (Yale Univ., New Haven, CT), Version 3.1.
17. Brünger, A. T. (1992) Nature (London) 355, 472-475.
18. Brünger, A. T., Krukowski, A. & Erickson, J. W. (1990) Acta Crystallogr. A 46, 585-593.
19. Jones, T. A. & Kjeldgaard, M. (1994) in From First Map to Final Model: Proceedings of the CCP4 Study Weekend, eds. Bailey, S., Hubbard, R. & Waller, D. (Daresbury Lab., Warrington, U.K.), pp. 1-13.
20. Luzzati, V. (1952) Acta Crystallogr. A 5, 801-810.
21. Kraulis, P. (1991) J. Appl. Crystallogr. 24, 946-950.
22. Eberhard, J., Raescckc, H.-R., Schmid, J. & Amrhein, N. (1993) FEBS Lett. 334, 233-236.