Source of nonlinearity in echo-time-dependent BOLD fMRI

Magnetic Resonance in Medicine

Volumn 55, Issue 6, 2006, Pages 1281-1290

  Jin, Tao ^a   Wang, Ping ^a   Tasker, Michelle ^a   Zhao, Fuqiang ^a   Kim, Seong Gi ^a,b  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

9.4 T; BOLD; fMRI; Gradient echo; Linearity; Spin echo; TE dependence

Indexed keywords

DATA ACQUISITION; SPIN POLARIZATION;

9.4 T; BOLD; FMRI; GRADIENT ECHO; LINEARITY; SPIN ECHO;

PHYSIOLOGY;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CAT; COMPARTMENT MODEL; COMPUTER SIMULATION; CONTRAST ENHANCEMENT; CONTROLLED STUDY; DEVICE; DIFFUSION WEIGHTED IMAGING; ECHO PLANAR IMAGING; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; MATHEMATICAL MODEL; NONHUMAN; OXYGEN BLOOD LEVEL; QUANTITATIVE ANALYSIS;

EID: 33744955983     PISSN: 07403194     EISSN: 15222594     Source Type: Journal    
DOI: 10.1002/mrm.20918     Document Type: Article

References (38)

1. Kim S-G, Ugurbil K. Comparison of blood oxygenation and cerebral blood flow effects in fMRI: estimation of relative oxygen consumption change. Magn Reson Med 1997;38:59-65.
2. Kim S-G, Rostrup E, Larsson HBW, Ogawa S, Paulson OB. Simultaneous measurements of CBF and CMRO2 changes by fMRI: significant increase of oxygen consumption rate during visual stimulation. Magn Reson Med 1999;41:1152-1161.
3. Lu H, Golay X, Pekar J, van Zijl PC. Sustained poststimulus elevation in cerebral oxygen utilization after vascular recovery. J Cereb Blood Flow Metab 2004;24:764-770.
4. Yacoub E, Duong TQ, Van De Moortele P, Lindquist M, Adriany G, Kim S-G, Ugurbil K, Hu X. Spin-echo fMRI in humans using high spatial resolutions and high magnetic fields. Magn Reson Med 2003;49:655-664.
5. Duong TQ, Yacoub E, Adriany G, Hu X, Ugurbil K, Kim S-G. Microvascular BOLD contribution at 4 and 7T in the human brain: gradient-echo and spin-echo fMRI with suppression of blood effects. Magn Reson Med 2003;49:1019-1027.
6. Lee S-P, Silva AC, Ugurbil K, Kim S-G. Diffusion-weighted spin-echo fMRI at 9.4 T: microvascular/tissue contribution to BOLD signal change. Magn Reson Med 1999;42:919-928.
7. Stroman PW, Tomanek B, Krause V, Frankenstein UN, Malisza KL. Functional magnetic resonance imaging of the human brain based on signal enhancement by extravascular protons (SEEP fMRI). Magn Reson Med 2003;49:433-439.
8. Stroman PW, Krause V, Frankenstein UN, Malisza KL, Tomanek B. Characterization of contrast changes in functional MRI of the human. Magn Reson Imaging 2001;19:827.
9. Jochimsen TH, Norris DG, Moller HE. Is there a change in water proton density associated with functional magnetic resonance imaging? Magn Reson Med 2005;53:470.
10. Menon RS, Ogawa S, Tank DW, Ugurbil K. 4 Tesla gradient recalled echo characteristics of photic stimulation-induced signal changes in the human primary visual cortex. Magn Reson Med 1993;30:380-386.
11. Silvennoinen M, Clingman CS, Golay X, Kauppinen RA, van Zijl PC. Comparison of the dependence of blood R2 and R2* on oxygen saturation at 1.5 and 4.7 Tesla. Magn Reson Med 2003;49:47-60.
12. Spees W, Yablonskiy D, Oswood M, Ackerman JH. Water proton MR properties of human blood at 1.5 Tesla: magnetic susceptibility, T1, T2, T*2, and non-Lorentzian signal behavior. Magn Reson Med 2001;45: 533-542.
13. LeBihan D, Breton E, Lallemand D, Grenier P, Cabanis E, Laval-Jeantet M. MR imaging of intravoxel incoherent motions: application to diffusion and perfusion in nerologic disorders. Radiology 1986;161:401-407.
14. Stejskal EO, Tanner JE. Spin diffusion measurements: spin echoes in the presence of a time-dependent field gradient. J Chem Physics 1965; 42:288-292.
15. Boxerman JL, Bandettini PA, Kwong KK, Baker JR, Davis TL, Rosen BR, Weisskoff RM. The intravascular contribution to fMRI signal change: Monte Carlo modeling and diffusion-weighted studies in vivo. Magn Reson Med 1995;34:4-10.
16. Song AW, Wong EC, Tan SG, Hyde JS. Diffusion-weighted fMRI at 1.5T. Magn Reson Med 1996;35:155-158.
17. Tsekos NV, Zhang F, Merkle H, Nagayama M, Iadecola C, Kim S-G. Quantitative measurements of cerebral blood flow in rats using the FAIR technique: correlation with previous iodoantipyrine autoradiographic studies. Magn Reson Med 1998;39:564-573.
18. Luz Z, Meiboom S. Nuclear magnetic resonance study of the protolysis of trimethyammonium ion in aqueous solution-order of the reaction with respect to solvent. J Chem Phys 1963;39:366-370.
19. Carr HY, Purcell EM. Effects of diffusion on free precession in nuclear magnetic resonance experiments. Phys Rev 1954;94:630-638.
20. Thulborn KR, Waterton JC, Mattews PM, Radda GK. Oxygenation dependence of the transverse relaxation time of water protons in whole blood at high field. Biochem Biophys Acta 1982;714:265-270.
21. Jensen JH, Chandra R. NMR relaxation in tissues with weak magnetic inhomogeneities. Magn Reson Med 2000;44:144-156.
22. Silvennoinen J. A study of NMR relaxation in blood-mechanistic considerations and implications for quantitative functional MRI. Kuopio: University of Kuopio; 2002.
23. Meyer M, Yu O, Eclancher B, Grucker D, Chambron J. NMR relaxation rates and blood oxygenation level. Magn Reson Med 1995;34:234-241.
24. Bryant R, Marill K, Blackmore C, Francis C. Magnetic relaxation of blood and blood clots. Magn Reson Med 1990;13:133-144.
25. Wright GA, Hu BS, Macovski A. Estimating oxygen saturation of blood in vivo with MR imaging at 1.5 T. J Magn Reson Imaging 1991;1:275-283.
26. Haacke EM, Lai S, Reichenbach JR, Kuppusamy K, Hoogenraad F, Takeichi H, Lin W. In vivo measurement of blood oxygen saturation using magnetic resonance imaging: a direct validation of the blood oxygen level-dependent concept in functional brain imaging. Hum Brain Mapp 1997;5:341-346.
27. Jochimsen TH, Norris DG, Mildner T, Moller HE. Quantifying the intra- and extravascular contributions to spin-echo fMRI at 3 T. Magn Reson Med 2004;52:724.
28. Harel N, Lee S-P, Nagaoka T, Kim D-S, Kim S-G. Origin of negative blood oxygenation level-dependent fMRI signals. J Cereb Blood Flow Metab 2002;22:908-917.
29. Strupp JP. Stimulate: A GUI based fMRI analysis software package. Neuroimage 1996;3:S607.
30. Zhao F, Wang P, Kim S-G. Cortical depth-dependent gradient-echo and spin-echo BOLD fMRI at 9.4T. Magn Reson Med 2004;51:518-524.
31. 2 measurements on a 1.5 Tesla commercial imager. Radiology 1989;171: 273-276.
32. Hulvershorn J, Bloy L, Gualtiere EE, Leigh JS, Elliott MA. A two compartment model for spin echo BOLD contrast: validation at 3T. In: Proceedings of the 12th Annual Meeting of ISMRM, Kyoto, Japan, 2004. p 1065.
33. Lu H, Golay X, Pekar J, Van Zijl P. Functional magnetic resonance imaging based on changes in vascular space occupancy. Magn Reson Med 2003;50:263-274.
34. Golay X, Silvennoinen M, Zhou J, Clingman CS, Kauppinen RA, Pekar J, van Zijl PC. Measurement of tissue oxygen extraction ratios from venous blood T2: increased precision and validation of principle. Magn Reson Med 2001;46:282-291.
35. Birn R, Bodurka J, Petridou N, Bandettini P. Experimental determination of the effect of T2′ changes in spin-echo EPI. In: Proceedings of the 12th Annual Meeting of ISMRM, Kyoto, Japan, 2004. p 997.
36. Birn R, Bandettini P. The effect of T2′ changes on spin-echo EPI-derived brain activation maps. In: Proceedings of the 10th Annual Meeting of ISMRM, Honolulu, HI, USA, 2002. p 1324.
37. Keilholz SD, Silva AC, Duyn J, Koretsky AP. The contribution of T2* to spin-echo EPI: implications for high-field fMRI studies. In: Proceedings of the 13th Annual Meeting of ISMRM, Miami, FL, USA, 2005. p 32.
38. Herscovitch P, Raichle ME. What is the correct value for the brain-blood partition coefficient for water? J Cereb Blood Flow Metab 1985;5:65-69.