Extension of the single amino acid chelate concept (SAAC) to bifunctional biotin analogues for complexation of the M(CO)3 +1 core (M = Tc and Re): Syntheses, characterization, biotinidase stability, and avidin binding

Bioconjugate Chemistry

Volumn 17, Issue 3, 2006, Pages 579-589

  James, Shelly ^a   Maresca, Kevin P ^c   Allis, Damian G ^a   Valliant, John F ^b   Eckelman, William ^c   Babich, John W ^c   Zubieta, Jon ^a  

^a SYRACUSE UNIVERSITY   (United States)

^b MCMASTER UNIVERSITY   (Canada)

^c A Subsidiary of Lantheus Holdings   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHELATION; COENZYMES; GLYCOPROTEINS; MEDICAL APPLICATIONS; SYNTHESIS (CHEMICAL); TECHNETIUM; TUMORS;

AMINO-ACIDS; BI-FUNCTIONAL; BIOMEDICAL APPLICATIONS; ELEVATED TEMPERATURE; IN-VIVO; STABLE COMPLEXES; TARGETED RADIOTHERAPY; TARGETING MOLECULES; THERAPEUTIC APPLICATION; TUMOR MODELS;

AMINO ACIDS;

AMIDE; AMINO ACID DERIVATIVE; AVIDIN; BIOTIN DERIVATIVE; BIOTINIDASE; CARBOXYLIC ACID; CHELATE; CYSTEINE; HISTIDINE; LYSINE; LYSINE DERIVATIVE; RADIOISOTOPE; RHENIUM COMPLEX; TECHNETIUM 99M; TECHNETIUM COMPLEX; TRANSITION ELEMENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BETA SHEET; BINDING SITE; BIOACCUMULATION; CALCULATION; COMPLEX FORMATION; ENZYME STABILITY; ISOTOPE LABELING; MOLECULAR STABILITY; NONHUMAN; PROTEIN BINDING; RADIOCHEMISTRY; RAT; SIMULATION; SYNTHESIS; TEMPERATURE DEPENDENCE; TUMOR LOCALIZATION; TUMOR MODEL;

EID: 33744933696     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc050297w     Document Type: Article

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