Knockdown of survivin gene by vector-based short hairpin RNA technique induces apoptosis and growth inhibition in Burkitt's lymphoma Raji cell line

Neoplasma

Volumn 53, Issue 3, 2006, Pages 206-212

  Gu, Cong Min ^a   Zhu, You Kai ^b   Ma, Yi Hui ^c   Zhang, Meng ^a   Liao, Bing ^a   Wu, Hong Yang ^a   Lin, Han Liang ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b PEOPLE'S HOSPITAL OF GUANGXI ZHUANG AUTONOMOUS REGION   (China)

^c HENAN PROVINCIAL PEOPLE'S HOSPITAL   (China)

Author keywords

Apoptosis; Non Hodgkin's lymphoma; Raji; RNAi; shRNA; Survivin

Indexed keywords

MESSENGER RNA; SHORT HAIRPIN RNA; TRYPAN BLUE;

APOPTOSIS; ARTICLE; BURKITT LYMPHOMA; CANCER CELL CULTURE; CANCER SURVIVAL; CELL PROLIFERATION; CELL TRANSFER; CONTROLLED STUDY; FLOW CYTOMETRY; GENE EXPRESSION; GENE VECTOR; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; PROTEIN EXPRESSION; RAJI CELL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING;

EID: 33744926722     PISSN: 00282685     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (34)

1. AMBROSINI G, ADIDA C, ALTIERI DC. A novel anti-apoptosis gene, Survivin, expressed in cancer and lymphoma. Nat Med 1997; 3: 917-921.
2. ALTIERI DC. Survivin, versatile modulation of cell division and apoptosis in cancer. Oncogene 2003; 22: 8581-8589.
3. ADIDA C, CROTTY PL, MCGRATH J, BERREBI D, DIEBOLD J et al. Developmentally regulated expression of the novel cancer antiapoptosis gene Survivin in human and mouse differentiation. Am J Pathol 1998; 152: 43-49.
4. TAMM I, WANG Y, SAUSVILLE E, SCUDIERO DA, VIGNA N et al. IAP-family protein Survivin inhibits caspase activity and apoptosis induced by Fas (CD95), Bax, caspases, and anticancer drugs. Cancer Res 1998; 58(23): 5315-5320.
5. LI F, AMBROSINI G, CHU EY, PLESCIA J, TOGNIN S et al. Control of apoptosis and mitotic spindle checkpoint by Survivin. Nature 1998; 396(6711): 580-584.
6. MONZO M, ROSELL R, FELIP E, ASTUDILLO J, SANCHEZ JJ et al. A novel anti-apoptosis gene: Re-expression of Survivin messenger RNA as a prognosis marker in non-small-cell lung cancers. J Clin Oncol 1999; 17(7): 2100-2104.
7. SWANA HS, GROSSMAN D, ANTHONY JN, WEISS RM, ALTIERI DC. Tumor content of the antiapoptosis molecule Survivin and recurrence of bladder cancer. N Engl J Med 1999; 341(6): 452-453.
8. JACOBSON JO, WILKES BM, KWAIATKOWSKI DJ, MEDEIROS IJ, AISENBERG AC et al. bcl-2 rearrangements in de novo diffuse large cell lymphoma. Association with distinctive clinical features. Cancer 1993; 72: 231-236.
9. DIERLAMM J, BAENS M, WLODARSKA I, STEFANOVA-OUZOUNOVA M, HERNANDEZ et al. The apoptosis inhibitor gene API2 and a novel 18q gene, MLT, are recurrently rearranged in the t(11;18)(q21;q21) associated with mucosa-associated lymphoid tissue lymphomas. Blood 1999; 93: 3601-3609.
10. ADIDA C, HAIOUN C, GAULARD P, LEPAGE E, MOREL P et al. Prognostic significance of Survivin expression in diffuse large B-cell lymphomas. Blood 2000; 96(5): 1921-1925.
11. ANSELL SM, ARENDT BK, GROTE DM, JELINEK DF, NOVAK AJ et al. Inhibition of Survivin expression surppresses the growth of aggressive non-Hodgkin's lymphoma. Leukemia 2004; 18(3): 616-623.
12. CARTHEW RW. Gene silencing by double-stranded RNA. Curr Opin Cell Biol 2001; 13(2): 244-248.
13. PADDISON PJ, CAUDY AA, BERNSTEIN E, HANNON GJ, CONKLIN DS. Short hairpin RNAs (shRNA) induce sequence-specific silencing in mammalian cells. Genes Dev 2002; 16: 948-958.
14. BRUMMELKAMP TR, BERNARDS R, AGAMI R. A system for stable expression of short interfering RNAs in mammalian cells. Science 2002; 296: 550-553.
15. XIANG LING, FENGZHI LI. Silencing of antiapoptotic Survivin gene by multiple approaches of RNA interference technology. BioTechniques 2004; 36: 450-460.
16. CZAUDERNA F, FECHTNER M, AYGUN H, AMOLD W, KLIPPEL A et al. Functional studies of the PI(3)-kinase signaling pathway employing synthetic and expressed shRNA. Nucleic Acid Res 2003; 31: 670-682.
17. OLIE RA, SIMES-WÜST AP, BAUMANN B, LEECH SH, FABBRO D et al. A novel antisense oligonucleotide targeting survivin expression induces apoptosis and sensitizes lung cancer cells to chemotherapy. Cancer Res 2000; 60: 2805-2809.
18. AMBROSINI G, ADIDA C, SIRUGO G, ALTIERI, DC. Induction of apoptosis and inhibition of cell proliferation by survivin gene targeting. J Biol Chem 1998; 273: 11177-11182.
19. MESRI M, WALL NR, LI J, KIM RW, ALTIERI DC. Cancer gene therapy using a survivin mutant adneovirus. J Clin Invest 2001; 108: 981-990.
20. PENNATI M, COLELLA G, FOLINI M, CITTI L, DAIDONE MG et al. Ribozyme-mediated attenuation of survivin expression sensitizes human melanoma cells to cisplatin-induced apoptosis. J Clin Invest 2002; 109: 285-286.
21. PENNATI M, CAMPBELL AJ, CURTO M, BINDA M, CHENG Y et al. Potentiation of paclitaxel-induced apoptosis by the novel cyclin-dependent kinase inhibitor NU6140: a possible role for survivin down-regulation. Mol Cancer Ther 2005; 4(9): 1328-1337.
22. CARVALHO A, CARMENA M, SAMBADE C, EARNSHAW WC, WHEATLEY SP. Survivin is required for stable checkpoint activation in taxol-treated HeLa cells. J Cell Sci 2003; 116: 2987-2998.
23. SQCHENG, WL WANG, WEI YAN, QL LI, LI WANG et al. Knockdown of Survivin gene expression by RNAi induces apoptosis in human hepatocellular carcinoma cell line SMMC-7721. World J Gastroenterol 2005; 11(5): 756-769.
24. CARVALHO A, CARMENA M, SAMBADE C, EARNSHAW WC, WHEATLEY SP. Survivin is required for stable checkpoint activation in taxol-treated HeLa cells. J Cell Sci 2003; 116(Pt 14): 2987-2998.
25. WILLIAMS NS, GAYNOR RB, SCOGGIN S, VERMA U, GOKASLAN T et al. Identification and validation of genes involved in the pathogenesis of colorectal cancer using cDNA microarrays and RNA interference. Clin Cancer Res 2003; 9 (3): 931-946.
26. WANG Y, ZHU H, QUAN L, ZHOU C, BAI J et al. Downregulation of Survivin by RNAi inhibits the growth of esophageal carcinoma cells. Cancer Biol Ther 2005; 4(9).
27. CHAWLA-SARKAR M, BAE SI, REU FJ, JACOBS BS, LINDNER DJ. Downregulation of Bcl-2, FLIP or IAPs (XIAP and Survivin) by siRNAs sensitizes resistant melanoma cells to Apo2L/TRAIL-induced apoptosis. Cell Death Differ. 2004; 11(8): 915-923.
28. KAPPLER M, BACHE M, BARTEL F, KOTZSCH M, PANIAN M et al. Knockdown of Survivin expression by small interfering RNA reduces the clonogenic survival of human sarcoma cell lines independently of p53. Cancer Gene Ther 2004; 11(3): 186-193.
29. KAPPLER M, TAUBERT H, BARTEL F et al. Radiosensitization, after a combined treatment of survivin siRNA and irradiation, is correlated with the activation of caspases 3 and 7 in a wtp53 sarcoma cell line, but not in a mt-p53 sarcoma cell line. Oncol Rep 2005; 13: 167-172.
30. BLANC-BRUDE OP, MESRI M, WALL NR, PLESCIA J, DOHI T et al. Therapeutic targeting of the survivin pathway in cancer: initiation of mitochondrial apoptosis and suppression of tumor-associated angiogenesis. Clin Cancer Res 2003; 9(7): 2683-2692.
31. COMA S, NOE V, LAVARINO C, ADAN J, RIVAS M et al. Use of siRNAs and antisense oligonucleotides against Survivin RNA to inhibit steps leading to tumor angiogenesis. Oligonucleotides 2004; 14: 100-113.
32. YU JY, DERUITER SL, TURNER DL. RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells. Proc Natl Acad Sci USA 2002; 99: 6047-6052.
33. SUI G, SOOHOO C, AFFAR B, GAY F, SHI F et al. A DNA vector-based RNAi technology to suppress gene expression in mammalian cells. Proc Natl Acad Sci USA 2002; 99(8): 5515-5520.
34. Database of pSilencer™ 4.1-CMVneo plasmid vector [internet]. Available from http://www.ambion.com.