Crotoxin induces actin reorganization and inhibits tyrosine phosphorylation and activity of small GTPases in rat macrophages

Toxicon

Volumn 47, Issue 8, 2006, Pages 909-919

  Sampaio, S C ^a   Santos, M F ^b   Costa, E P ^b   Rangel Santos, A C ^a   Carneiro, S M ^a   Curi, R ^b   Cury, Y ^a  

^a INSTITUTO BUTANTAN   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Actin cytoskeleton; Crotalus durissus terrificus venom; Crotoxin; Macrophage; Phagocytosis; Rho GTPases

Indexed keywords

ACTIN; CROTOXIN; F ACTIN; GUANOSINE TRIPHOSPHATASE; LIPOXYGENASE INHIBITOR; MEMBRANE ENZYME; PHOSPHOTYROSINE; PROTEIN SUBUNIT; RAC1 PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; SNAKE VENOM; TYROSINE; ZILEUTON; ZYMOSAN;

ACTIN FILAMENT; ANIMAL CELL; ANIMAL MODEL; ARTICLE; CELL LEVEL; CELL SPREADING; CELL SURFACE; CONTROLLED STUDY; CYTOPLASM; CYTOSKELETON; CYTOTOXICITY; ENVENOMATION; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INHIBITION; IMMUNOCYTOCHEMISTRY; MACROPHAGE; MACROPHAGE FUNCTION; MALE; MEMBRANE TRANSPORT; NONHUMAN; OPSONIZATION; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; TRANSMISSION ELECTRON MICROSCOPY;

ACTINS; ANIMALS; CROTALUS; CROTOXIN; MACROPHAGES, PERITONEAL; MALE; PHOSPHOLIPASES A; PHOSPHORYLATION; RATS; RATS, WISTAR; RHO GTP-BINDING PROTEINS; SNAKE VENOMS; TYROSINE;

CROTALUS DURISSUS TERRIFICUS;

EID: 33744924194     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2006.03.004     Document Type: Article

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