Novel synthesis of sterically hindered N-substituted lactams from imides

Tetrahedron Letters

Volumn 47, Issue 28, 2006, Pages 4877-4880

  Sannigrahi, Mousumi ^a   Pinto, Patrick ^a   Chan, T M ^a   Shih, Neng Yang ^a   George Njoroge, F ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETAL DERIVATIVE; IMIDE; LACTAM DERIVATIVE; PYRIDONE DERIVATIVE;

ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS; MATERIALS; STEREOCHEMISTRY; STEREOSPECIFICITY; SUBSTITUTION REACTION;

EID: 33744823292     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2006.05.037     Document Type: Article

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16. 3): δ ppm: 0.97 (s, 12H); 1.38 (s, 9H); 1.57 (s, 3H); 2.14 (s, 2H); 2.62 (m, 1H); 3.15 (m, 1H); 3.51 (m, 1H); 3.71 (9m, 1H); 4.30 (t, 1H, J = 12.8 Hz); 4.71 (d, 1H, J = 10.2 Hz).