Novel Reductive Amination of Nitriles: An Efficient Route to 5-Hydroxypiperidone-Derived N,N-Acetals

Advanced Synthesis and Catalysis

Volumn 345, Issue 4, 2003, Pages 483-487

  Vink, Mandy K S ^a   Schortinghuis, Christien A ^b   Mackova Zabelinskaja, Antonina ^c   Fechter, Martin ^c   Pöchlauer, Peter ^d   Castelijns, A Marianne C F ^e   Van Maarseveen, Jan H ^a   Hiemstra, Henk ^a   Griengl, Herfried ^c   Schoemaker, Hans E ^e   Rutjes, Floris P J T ^b  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b RADBOUD UNIVERSITY NIJMEGEN   (Netherlands)

^c GRAZ UNIVERSITY OF TECHNOLOGY   (Austria)

^d DSM Fine Chemicals Austria Nfg GmbH & Co KG   (Netherlands)

^e DSM RESEARCH   (Netherlands)

Author keywords

(S) HbHNL; Cyanohydrin; Hydroxylactam; N,N acetals; Nitrile hydrogenation

Indexed keywords

5 HYDROXYPIPERIDIN 2 ONE; ACETAL DERIVATIVE; CYANOHYDRIN; PIPERIDONE DERIVATIVE; UNCLASSIFIED DRUG;

AMINATION; ARTICLE; BIOCATALYST; ENANTIOSELECTIVITY; REDUCTION; SYNTHESIS;

EID: 0242522450     PISSN: 16154150     EISSN: None     Source Type: Journal    
DOI: 10.1002/adsc.200390054     Document Type: Article

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