-
1
-
-
0032483550
-
Specific synergy of multiple substrate-receptor interactions in platelet thrombus formation under flow
-
Savage, B., Almus-Jacobs, F., and Ruggeri, Z. M. (1998) Specific synergy of multiple substrate-receptor interactions in platelet thrombus formation under flow, Cell 94, 657-666.
-
(1998)
Cell
, vol.94
, pp. 657-666
-
-
Savage, B.1
Almus-Jacobs, F.2
Ruggeri, Z.M.3
-
2
-
-
0032523064
-
Integrin signaling: The platelet paradigm
-
Shattil, S. J., Kashiwagi, H., and Pampori, N. (1998) Integrin signaling: the platelet paradigm, Blood 91, 2645-2657.
-
(1998)
Blood
, vol.91
, pp. 2645-2657
-
-
Shattil, S.J.1
Kashiwagi, H.2
Pampori, N.3
-
3
-
-
0037145037
-
Integrins: Bidirectional, allosteric signaling machines
-
Hynes, R. O. (2002) Integrins: bidirectional, allosteric signaling machines, Cell 110, 673-687.
-
(2002)
Cell
, vol.110
, pp. 673-687
-
-
Hynes, R.O.1
-
4
-
-
16644368209
-
Integrin bidirectional signaling: A molecular view
-
Qin, J., Vinogradova, O., and Plow, E. F. (2004) Integrin bidirectional signaling: a molecular view, PLoS Biol. 2, 0726-0729.
-
(2004)
PLoS Biol.
, vol.2
, pp. 726-729
-
-
Qin, J.1
Vinogradova, O.2
Plow, E.F.3
-
5
-
-
0034652205
-
A structural basis for integrin activation by the cytoplasmic tail of the alpha IIb-subunit
-
Vinogradova, O., Haas, T., Plow, E. F., and Qin, J. (2000) A structural basis for integrin activation by the cytoplasmic tail of the alpha IIb-subunit, Proc. Natl. Acad. Sci. U.S.A. 97, 1450-1455.
-
(2000)
Proc. Natl. Acad. Sci. U.S.A.
, vol.97
, pp. 1450-1455
-
-
Vinogradova, O.1
Haas, T.2
Plow, E.F.3
Qin, J.4
-
6
-
-
1642529548
-
Membrane-mediated structural transitions at the cytoplasmic face during integrin activation
-
Vinogradova, O., Vaynberg, J., Kong, X., Haas, T. A., Plow, E. F., and Qin, J. (2004) Membrane-mediated structural transitions at the cytoplasmic face during integrin activation, Proc. Natl. Acad. Sci. U.S.A. 101, 4094-4099.
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 4094-4099
-
-
Vinogradova, O.1
Vaynberg, J.2
Kong, X.3
Haas, T.A.4
Plow, E.F.5
Qin, J.6
-
7
-
-
0029966310
-
Breaking the integrin hinge. A defined structural constraint regulates integrin signaling
-
Hughes, P. E., Diaz-Gonzalez, F., Leong, L., Wu, C., McDonald, J. A., Shattil, S. J., and Ginsberg, M. H. (1996) Breaking the integrin hinge. A defined structural constraint regulates integrin signaling, J. Biol. Chem. 271, 6571-6574.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 6571-6574
-
-
Hughes, P.E.1
Diaz-Gonzalez, F.2
Leong, L.3
Wu, C.4
McDonald, J.A.5
Shattil, S.J.6
Ginsberg, M.H.7
-
8
-
-
0037031551
-
A structural mechanism of integrin αIIbβ3 "inside- out" activation as regulated by its cytoplasmic face
-
Vinogradova, O., Velyvis, A., Velyviene, A., Hu, B., Haas, T. A., Plow, E. F., and Qin, J. (2002) A structural mechanism of integrin αIIbβ3 "inside-out" activation as regulated by its cytoplasmic face, Cell 110, 587-597.
-
(2002)
Cell
, vol.110
, pp. 587-597
-
-
Vinogradova, O.1
Velyvis, A.2
Velyviene, A.3
Hu, B.4
Haas, T.A.5
Plow, E.F.6
Qin, J.7
-
9
-
-
0037197990
-
Solution structures of the cytoplasmic tail complex from platelet integrin αIIb- and β3-subunits
-
Weljie, A. M., Hwang, P. M., and Vogel, H. (2002) Solution structures of the cytoplasmic tail complex from platelet integrin αIIb- and β3-subunits, Proc. Natl. Acad. Sci. U.S.A. 99, 5878-5883.
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 5878-5883
-
-
Weljie, A.M.1
Hwang, P.M.2
Vogel, H.3
-
10
-
-
0033546169
-
3 and to calcium-and integrin-binding protein
-
3 and to calcium-and integrin-binding protein, J. Biol. Chem. 274, 17257-17266.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 17257-17266
-
-
Vallar, L.1
Melchior, C.2
Plancon, S.3
Drobecq, H.4
Lippens, G.5
Regnault, V.6
Kieffer, N.7
-
11
-
-
0029665001
-
3: A ternary complex of the integrin α and β subunits and a divalent cation
-
3: a ternary complex of the integrin α and β subunits and a divalent cation, J. Biol. Chem. 271, 6017-6026.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 6017-6026
-
-
Haas, T.A.1
Plow, E.F.2
-
12
-
-
0035041854
-
C-terminal opening mimics "inside-out" activation of integrin alpha5beta1
-
Takagi, J., Erickson, H. P., and Springer, T. A. (2001) C-terminal opening mimics "inside-out" activation of integrin alpha5beta1, Nat. Struct. Biol. 8, 412-416.
-
(2001)
Nat. Struct. Biol.
, vol.8
, pp. 412-416
-
-
Takagi, J.1
Erickson, H.P.2
Springer, T.A.3
-
13
-
-
0042681786
-
Bidirectional transmembrane signaling by cytoplasmic domain separation in integrins
-
Kim, M., Carman, C. V., and Springer, T. A. (2003) Bidirectional transmembrane signaling by cytoplasmic domain separation in integrins, Science 301, 1720-1725.
-
(2003)
Science
, vol.301
, pp. 1720-1725
-
-
Kim, M.1
Carman, C.V.2
Springer, T.A.3
-
15
-
-
0028954275
-
Regulation of integrin affinity states through an NPXY motif in the β subunit cytoplasmic domain
-
O'Toole, T. E., Ylanne, J., and Culley, B. M. (1995) Regulation of integrin affinity states through an NPXY motif in the β subunit cytoplasmic domain, J. Biol. Chem. 270, 8553-8558.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 8553-8558
-
-
O'Toole, T.E.1
Ylanne, J.2
Culley, B.M.3
-
16
-
-
0028174243
-
Inside-out" signal transduction initiated by isolated integrin cytoplasmic domains
-
Chen, Y. P., O'Toole, T. E., Shipley, T., Forsyth, J., LaFlamme, S. E., Yamada, K. M., Shattil, S. J., and Ginsberg, M. H. (1994) "Inside-out" signal transduction initiated by isolated integrin cytoplasmic domains, J. Biol. Chem. 269, 18307-18310.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 18307-18310
-
-
Chen, Y.P.1
O'Toole, T.E.2
Shipley, T.3
Forsyth, J.4
Laflamme, S.E.5
Yamada, K.M.6
Shattil, S.J.7
Ginsberg, M.H.8
-
17
-
-
0042672885
-
Critical roles for the COOH-terminal NITY and RGT sequences of the integrin beta3 cytoplasmic domain in inside-out and outside-in signaling
-
Xi, X., Bodnar, R. J., Li, Z., Lam, S. C., and Du, X. (2003) Critical roles for the COOH-terminal NITY and RGT sequences of the integrin beta3 cytoplasmic domain in inside-out and outside-in signaling, J. Cell Biol. 162, 329-339.
-
(2003)
J. Cell Biol.
, vol.162
, pp. 329-339
-
-
Xi, X.1
Bodnar, R.J.2
Li, Z.3
Lam, S.C.4
Du, X.5
-
18
-
-
0037238844
-
Structural determinants of integrin recognition by talin
-
Garcia-Alvarez, B., de Pereda, J. M., Calderwood, D. A., Ulmer, T. S., Critchley, D., Campbell, I. D., Ginsberg, M. H., and Liddington, R. C. (2003) Structural determinants of integrin recognition by talin, Mol. Cell 11, 49-58.
-
(2003)
Mol. Cell
, vol.11
, pp. 49-58
-
-
Garcia-Alvarez, B.1
De Pereda, J.M.2
Calderwood, D.A.3
Ulmer, T.S.4
Critchley, D.5
Campbell, I.D.6
Ginsberg, M.H.7
Liddington, R.C.8
-
19
-
-
0141865705
-
Talin binding to integrin β tails: A final common step in integrin activation
-
Tadokoro, S., Shattil, S. J., Eto, K., Tai, V., Liddington, R. C., de Pereda, J. M., Ginsberg, M. H., and Calderwood, D. A. (2003) Talin binding to integrin β tails: a final common step in integrin activation, Science 302, 103-106.
-
(2003)
Science
, vol.302
, pp. 103-106
-
-
Tadokoro, S.1
Shattil, S.J.2
Eto, K.3
Tai, V.4
Liddington, R.C.5
De Pereda, J.M.6
Ginsberg, M.H.7
Calderwood, D.A.8
-
20
-
-
0021364892
-
Autoantibodies against the platelet glycoprotein IIb/IIIa complex in patients with chronic ITP
-
Woods, V. L., Jr., Oh, E. H., Mason, D., and McMillan, R. (1984) Autoantibodies against the platelet glycoprotein IIb/IIIa complex in patients with chronic ITP, Blood 63, 368-375.
-
(1984)
Blood
, vol.63
, pp. 368-375
-
-
Woods Jr., V.L.1
Oh, E.H.2
Mason, D.3
McMillan, R.4
-
21
-
-
0033213922
-
The Talin head domain binds to integrin beta subunit cytoplasmic tails and regulates integrin activation
-
Calderwood, D. A., Zent, R., Grant, R., Rees, D. J., Hynes, R. O., and Ginsberg, M. H. (1999) The Talin head domain binds to integrin beta subunit cytoplasmic tails and regulates integrin activation, J. Biol. Chem. 274, 28071-28074.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 28071-28074
-
-
Calderwood, D.A.1
Zent, R.2
Grant, R.3
Rees, D.J.4
Hynes, R.O.5
Ginsberg, M.H.6
-
22
-
-
0037077282
-
The phosphotyrosine binding (PTB)-like domain of talin activates integrins
-
Calderwood, D. A., Yan, B., de Pereda, J. M., Garcia-Alvarez, B., Fujioka, Y., Liddington, R. C., and Ginsberg, M. H. (2002) The phosphotyrosine binding (PTB)-like domain of talin activates integrins, J. Biol. Chem. 277, 21749-21758.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 21749-21758
-
-
Calderwood, D.A.1
Yan, B.2
De Pereda, J.M.3
Garcia-Alvarez, B.4
Fujioka, Y.5
Liddington, R.C.6
Ginsberg, M.H.7
-
23
-
-
0028285015
-
Integrin cytoplasmic domains mediate inside-out signal transduction
-
O'Toole, T. E., Katagiri, Y., Faull, R. J., Peter, K., Tamura, R., Quaranta, V., Loftus, J. C., Shattil, S. J., and Ginsberg, M. H. (1994) Integrin cytoplasmic domains mediate inside-out signal transduction, J. Cell Biol. 124, 1047-1059.
-
(1994)
J. Cell Biol.
, vol.124
, pp. 1047-1059
-
-
O'Toole, T.E.1
Katagiri, Y.2
Faull, R.J.3
Peter, K.4
Tamura, R.5
Quaranta, V.6
Loftus, J.C.7
Shattil, S.J.8
Ginsberg, M.H.9
-
24
-
-
0029048813
-
The conserved membrane-proximal region of an integrin cytoplasmic domain specifies ligand binding affinity
-
Hughes, P. E., O'Toole, T. E., Ylanne, J., Shattil, S. J., and Ginsberg, M. H. (1995) The conserved membrane-proximal region of an integrin cytoplasmic domain specifies ligand binding affinity, J. Biol. Chem. 270, 12411-12417.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 12411-12417
-
-
Hughes, P.E.1
O'Toole, T.E.2
Ylanne, J.3
Shattil, S.J.4
Ginsberg, M.H.5
-
25
-
-
0026614923
-
3 (GPIIb-IIIa) in a variant of Glanzmann's thrombasthenia
-
3 (GPIIb-IIIa) in a variant of Glanzmann's thrombasthenia, Proc. Natl. Acad. Sci. U.S.A. 89, 10169-10173.
-
(1992)
Proc. Natl. Acad. Sci. U.S.A.
, vol.89
, pp. 10169-10173
-
-
Chen, Y.-P.1
Djaffar, I.2
Pidard, D.3
Steiner, B.4
Cieutat, A.-M.5
Caen, J.P.6
Rosa, J.-P.7
-
26
-
-
16644396938
-
A specific interface between integrin transmembrane helices and affinity for ligand
-
Luo, B. H., Springer, T. A., and Takagi, J. (2004) A specific interface between integrin transmembrane helices and affinity for ligand, PLoS Biol. 2, 776-786.
-
(2004)
PLoS Biol.
, vol.2
, pp. 776-786
-
-
Luo, B.H.1
Springer, T.A.2
Takagi, J.3
-
27
-
-
14844323604
-
Transmembrane domain helix packing stabilizes integrin alphallbbeta3 in the low affinity state
-
Partridge, A. W., Liu, S., Kim, S., Bowie, J. U., and Ginsberg, M. H. (2005) Transmembrane domain helix packing stabilizes integrin alphallbbeta3 in the low affinity state, J. Biol. Chem. 280, 7294-7300.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 7294-7300
-
-
Partridge, A.W.1
Liu, S.2
Kim, S.3
Bowie, J.U.4
Ginsberg, M.H.5
-
28
-
-
18944403970
-
A coiled-coil structure of the alphaIIb-beta3 integrin transmembrane and cytoplasmic domains in its resting state
-
Gottschalk, K. E. (2005) A coiled-coil structure of the alphaIIb-beta3 integrin transmembrane and cytoplasmic domains in its resting state, Structure 13, 703-712.
-
(2005)
Structure
, vol.13
, pp. 703-712
-
-
Gottschalk, K.E.1
-
29
-
-
0037195164
-
Three-dimensional model of the human platelet integrin alpha IIbbeta 3 based on electron cryomicroscopy and X-ray crystallography
-
Adair, B. D., and Yeager, M. (2002) Three-dimensional model of the human platelet integrin alpha IIbbeta 3 based on electron cryomicroscopy and X-ray crystallography, Proc. Natl. Acad. Sci. U.S.A. 99, 14059-14064.
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 14059-14064
-
-
Adair, B.D.1
Yeager, M.2
|