-
1
-
-
9244244135
-
192Ir intraluminal brachytherapy in treatment of malignant obstructive jaundice
-
192Ir intraluminal brachytherapy in treatment of malignant obstructive jaundice. World J Gastroenterol 10: 3506-3510, 2004.
-
(2004)
World J Gastroenterol
, vol.10
, pp. 3506-3510
-
-
Chen, Y.1
Wang, X.L.2
Yan, Z.P.3
Cheng, J.M.4
Wang, J.H.5
Gong, G.C.6
Qian, S.7
Luo, J.J.8
Liu, Q.X.9
-
2
-
-
0033608993
-
The ErbB-2/HER2 oncoprotein of human carcinoma may function solely as a shared coreceptor for multiple stroma-drived growth factors
-
Klapper LN, Glathe S, Vaisman N, Hynes NE, Andrews GC, Sela M and Yarden Y: The ErbB-2/HER2 oncoprotein of human carcinoma may function solely as a shared coreceptor for multiple stroma-drived growth factors. Proc Natl Acad Sci USA 96: 4995-5000, 1999.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 4995-5000
-
-
Klapper, L.N.1
Glathe, S.2
Vaisman, N.3
Hynes, N.E.4
Andrews, G.C.5
Sela, M.6
Yarden, Y.7
-
3
-
-
78650403683
-
Biliary metalic stenting and chemoradiation therapy for unresectable bile duct carcinoma
-
Suzuki M, Umino T, Katayo T, Takeuchi H, Oikawa M, Ono K, Hayashi Y, Satou T and Matsuno M: Biliary metalic stenting and chemoradiation therapy for unresectable bile duct carcinoma. J Biliary Tract Pancreas 22: 255-259, 2001.
-
(2001)
J Biliary Tract Pancreas
, vol.22
, pp. 255-259
-
-
Suzuki, M.1
Umino, T.2
Katayo, T.3
Takeuchi, H.4
Oikawa, M.5
Ono, K.6
Hayashi, Y.7
Satou, T.8
Matsuno, M.9
-
4
-
-
0027353561
-
Protein tyrosine kinase growth factor receptors and their ligands in development, differentiation, and cancer
-
Wilks AF: Protein tyrosine kinase growth factor receptors and their ligands in development, differentiation, and cancer. Adv Cancer Res 60: 43-73, 1993.
-
(1993)
Adv Cancer Res
, vol.60
, pp. 43-73
-
-
Wilks, A.F.1
-
5
-
-
0033063774
-
The epidermal growth factor receptor and its inhibition cancer therapy
-
Woodburn JR: The epidermal growth factor receptor and its inhibition cancer therapy. Pharmacol Ther 82: 241-250, 1999.
-
(1999)
Pharmacol Ther
, vol.82
, pp. 241-250
-
-
Woodburn, J.R.1
-
6
-
-
0035118561
-
Expression and clinical significance of the erbB family in intrahepatic cholangiocellular carcinoma
-
Ito Y, Takeda T, Sasaki T, Yamada T, Ishiguro S, Imaoka S, Tsujimoto M, Sakon M, Higashiyama S, Monden M and Matsuura N: Expression and clinical significance of erbB family in intrahepatic cholangiocellular carcinoma. Pathol Res Pract 197: 95-100, 2001. (Pubitemid 32194502)
-
(2001)
Pathology Research and Practice
, vol.197
, Issue.2
, pp. 95-100
-
-
Ito, Y.1
Ito, Y.2
Takeda, T.3
Sasaki, Y.4
Sakon, M.5
Yamada, T.6
Ishiguro, S.7
Imaoka, S.8
Tsujimoto, M.9
Higashiyama, S.10
Monden, M.11
Matsuura, N.12
-
7
-
-
37049183697
-
Human breast cancer: Correlation of relapse and survival with amplification of the HER2/neu oncogene
-
Slamon DJ, Clark GM, Wong SG, Levin WJ, Ullrich A and McGuire WL: Human breast cancer: correlation of relapse and survival with amplification of the HER2/neu oncogene. Science 235: 177-182, 1987.
-
(1987)
Science
, vol.235
, pp. 177-182
-
-
Slamon, D.J.1
Clark, G.M.2
Wong, S.G.3
Levin, W.J.4
Ullrich, A.5
McGuire, W.L.6
-
8
-
-
0033649626
-
Comoparative clinicopathological study of resected intrahepatic cholangiocarcinoma in northeast Thailand and Japan
-
Suzuki H, Isaji S, Pairojkul C and Uttaravichien T: Comoparative clinicopathological study of resected intrahepatic cholangiocarcinoma in northeast Thailand and Japan. J Hepatobiliary Pancreat Surg 7: 206-211, 2000.
-
(2000)
J Hepatobiliary Pancreat Surg
, vol.7
, pp. 206-211
-
-
Suzuki, H.1
Isaji, S.2
Pairojkul, C.3
Uttaravichien, T.4
-
9
-
-
0028869784
-
Significance of c-erbB-2 expression in normal and neoplastic epithelium of biliary tract
-
Chow NH, Huang SM, Chan SH, Mo LR, Hwang MH and Su WC: Significance of c-erbB-2 expression in normal and neoplastic epithelium of biliary tract. Anticancer Res 15: 1055-1060, 1995.
-
(1995)
Anticancer Res
, vol.15
, pp. 1055-1060
-
-
Chow, N.H.1
Huang, S.M.2
Chan, S.H.3
Mo, L.R.4
Hwang, M.H.5
Su, W.C.6
-
10
-
-
0036322129
-
ERBB-2 overexpression and cyclooxygenase-2 up-regulation in human chorangiocarcinoma and risk condition
-
Endo K, Yoon BI, Pairojkul C, Demetris AJ and Sirica AE: ERBB-2 overexpression and cyclooxygenase-2 up-regulation in human chorangiocarcinoma and risk condition. Hepatology 36: 439-450, 2002.
-
(2002)
Hepatology
, vol.36
, pp. 439-450
-
-
Endo, K.1
Yoon, B.I.2
Pairojkul, C.3
Demetris, A.J.4
Sirica, A.E.5
-
11
-
-
0027936755
-
A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells
-
Han J, Lee JD, Bibbs L and Ulevitch RJ: A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells. Science 265: 808-811, 1994.
-
(1994)
Science
, vol.265
, pp. 808-811
-
-
Han, J.1
Lee, J.D.2
Bibbs, L.3
Ulevitch, R.J.4
-
12
-
-
0028605318
-
A protein kinase involved in the regulation of inflammatory cytokinase biosynthesis
-
Lee JC, Laydon JT, McDonnnell PC, Gallagher TF, Kumar S, Green D, McNulty D, Blumenthal MJ, Heys JR and Landvatter SW: A protein kinase involved in the regulation of inflammatory cytokinase biosynthesis. Nature 372: 739-746, 1994.
-
(1994)
Nature
, vol.372
, pp. 739-746
-
-
Lee, J.C.1
Laydon, J.T.2
McDonnnell, P.C.3
Gallagher, T.F.4
Kumar, S.5
Green, D.6
McNulty, D.7
Blumenthal, M.J.8
Heys, J.R.9
Landvatter, S.W.10
-
13
-
-
0032815618
-
Radiation-induced release of transformating growth factor alpha activates the epidermal growth factor receptor and mitogen-activated protein kinase pathway in carcinoma cells, leading to increased proliferation and protection from radiation-induced cell death
-
Dent P, Reardon DB, Park JS, Bowers G, Logsdon C, Valerie K and Schmidt-Ullrich R: Radiation-induced release of transformating growth factor alpha activates the epidermal growth factor receptor and mitogen-activated protein kinase pathway in carcinoma cells, leading to increased proliferation and protection from radiation-induced cell death. Mol Biol Cell 10: 2493-2506, 1999.
-
(1999)
Mol Biol Cell
, vol.10
, pp. 2493-2506
-
-
Dent, P.1
Reardon, D.B.2
Park, J.S.3
Bowers, G.4
Logsdon, C.5
Valerie, K.6
Schmidt-Ullrich, R.7
-
14
-
-
0034029550
-
Ionizing radiation-induced mitogen-activated protein (MAP) kinase activation in DU145 prostate carcinoma cells: MAP kinase inhibition enhances radiation-induced cell killing and G2/M-phase arrest
-
Hagan M, Wang L, Hanley JR, Park JS and Dent P: Ionizing radiation-induced mitogen-activated protein (MAP) kinase activation in DU145 prostate carcinoma cells: MAP kinase inhibition enhances radiation-induced cell killing and G2/M-phase arrest. Radiat Res 153: 371-383, 2000.
-
(2000)
Radiat Res
, vol.153
, pp. 371-383
-
-
Hagan, M.1
Wang, L.2
Hanley, J.R.3
Park, J.S.4
Dent, P.5
-
15
-
-
0036467486
-
p38 and Chk1 kinases: Different conductors for the G(2)/M checkpoint symphony
-
Bulavin DV, Amundson SA and Fornace AJ: p38 and Chk1 kinases: different conductors for the G(2)/M checkpoint symphony. Curr Opin Genet Dev 12: 92-97, 2002.
-
(2002)
Curr Opin Genet Dev
, vol.12
, pp. 92-97
-
-
Bulavin, D.V.1
Amundson, S.A.2
Fornace, A.J.3
-
16
-
-
0033932013
-
RAS-mediated radiation resistance is not linked to MAP kinase activation in two bladder carcinoma cell lines
-
Gupta AK, Bakanauskas VJ, Cerniglia GJ, Cheng Y, Bernhard EJ, Muschel RJ and McKenna WG: RAS-mediated radiation resistance is not linked to MAP kinase activation in two bladder carcinoma cell lines. Radiat Res 154: 64-72, 2000.
-
(2000)
Radiat Res
, vol.154
, pp. 64-72
-
-
Gupta, A.K.1
Bakanauskas, V.J.2
Cerniglia, G.J.3
Cheng, Y.4
Bernhard, E.J.5
Muschel, R.J.6
McKenna, W.G.7
-
17
-
-
0033794712
-
MEK1 and ERK1/2 kinases as targets for the modulation of radiation responses
-
Claus B, Paul K, Justine R, Heidrun F, Michael B and Wilfried B: MEK1 and ERK1/2 kinases as targets for the modulation of radiation responses. Anticancer Res 20: 3243-3250, 2000.
-
(2000)
Anticancer Res
, vol.20
, pp. 3243-3250
-
-
Claus, B.1
Paul, K.2
Justine, R.3
Heidrun, F.4
Michael, B.5
Wilfried, B.6
-
18
-
-
0037099522
-
Ras mediates radiaoresistance through both phosphatidylinositol 3-kinase-dependent and Raf-dependent but mitogen-activated protein kinase/extracellular signal-regulated kinase kinase-independent signaling pathways
-
Grana TM, Rusyn EV, Zhou H, Sartor CI and Cox AD: Ras mediates radiaoresistance through both phosphatidylinositol 3-kinase-dependent and Raf-dependent but mitogen-activated protein kinase/extracellular signal-regulated kinase kinase-independent signaling pathways. Cancer Res 62: 4142-4150, 2002.
-
(2002)
Cancer Res
, vol.62
, pp. 4142-4150
-
-
Grana, T.M.1
Rusyn, E.V.2
Zhou, H.3
Sartor, C.I.4
Cox, A.D.5
-
19
-
-
0034745353
-
Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER2/neu-overexpressing cells
-
Zhou BP, Liao Y, Xia W, Spohn B, Lee MH and Hung MC: Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER2/neu-overexpressing cells. Nat Cell Biol 3: 245-252, 2001.
-
(2001)
Nat Cell Biol
, vol.3
, pp. 245-252
-
-
Zhou, B.P.1
Liao, Y.2
Xia, W.3
Spohn, B.4
Lee, M.H.5
Hung, M.C.6
-
20
-
-
0034941567
-
Akt-dependent phosphorylation of p21Cip1 regulates PCNA binding and proliferation of endothelial cells
-
Rossig L, Jadidi AS, Urbich C, Badorff C, Zeiher AM and Dimmeler S: Akt-dependent phosphorylation of p21Cip1 regulates PCNA binding and proliferation of endothelial cells. Mol Cell Biol 21: 5644-5657, 2001.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 5644-5657
-
-
Rossig, L.1
Jadidi, A.S.2
Urbich, C.3
Badorff, C.4
Zeiher, A.M.5
Dimmeler, S.6
-
21
-
-
0034852195
-
Akt/PKB promotes cancer cell invasion via increased motility and metalloprotease production
-
Kim D, Kim S, Koh H, Yoon SO, Chung AS, Cho KS and Chung J: Akt/PKB promotes cancer cell invasion via increased motility and metalloprotease production. FASEB J 15: 1953-1962, 2001.
-
(2001)
FASEB J
, vol.15
, pp. 1953-1962
-
-
Kim, D.1
Kim, S.2
Koh, H.3
Yoon, S.O.4
Chung, A.S.5
Cho, K.S.6
Chung, J.7
-
22
-
-
0035872443
-
The Ras radiation resistance pathway
-
Gupta AK, Bakanauskas VJ, Cerniglia GC, Cheng Y, Bernhard EJ, Muschel RJ and McKenna WG: The Ras radiation resistance pathway. Cancer Res 61: 4278-4282, 2001.
-
(2001)
Cancer Res
, vol.61
, pp. 4278-4282
-
-
Gupta, A.K.1
Bakanauskas, V.J.2
Cerniglia, G.C.3
Cheng, Y.4
Bernhard, E.J.5
Muschel, R.J.6
McKenna, W.G.7
-
23
-
-
0038281227
-
Radiation sensitization of human cancer cells in vivo by inhibiting the activity of PI3K using LY294002
-
Gupta AK, Cerniglia GJ, Mick R, Ahmed MS, Bakanauskas VJ, Muschel RJ and McKenna WG: Radiation sensitization of human cancer cells in vivo by inhibiting the activity of PI3K using LY294002. Int J Radiat Oncol Biol Phys 56: 846-853, 2003.
-
(2003)
Int J Radiat Oncol Biol Phys
, vol.56
, pp. 846-853
-
-
Gupta, A.K.1
Cerniglia, G.J.2
Mick, R.3
Ahmed, M.S.4
Bakanauskas, V.J.5
Muschel, R.J.6
McKenna, W.G.7
-
24
-
-
0037102157
-
Phosphatidylinositol 3-kinase/Akt signaling in the response of vascular endothelium to ionizing radiation
-
Edwards E, Geng L, Tan J, Onishko H, Donnelly E and Hallahan DE: Phosphatidylinositol 3-kinase/Akt signaling in the response of vascular endothelium to ionizing radiation. Cancer Res 62: 4671-4677, 2002.
-
(2002)
Cancer Res
, vol.62
, pp. 4671-4677
-
-
Edwards, E.1
Geng, L.2
Tan, J.3
Onishko, H.4
Donnelly, E.5
Hallahan, D.E.6
-
25
-
-
2442689399
-
Serine/threonine kinase AKT is frequently activated in human bile duct cancer and is association with increased radioresistance
-
Tanno S, Yanagawa N, Habiro A, Koizumi K, Nakano Y, Osanai M, Mizukami Y, Okumura T, Testa JR and Kohgo Y: Serine/threonine kinase AKT is frequently activated in human bile duct cancer and is association with increased radioresistance. Cancer Res 64: 3486-3490, 2004.
-
(2004)
Cancer Res
, vol.64
, pp. 3486-3490
-
-
Tanno, S.1
Yanagawa, N.2
Habiro, A.3
Koizumi, K.4
Nakano, Y.5
Osanai, M.6
Mizukami, Y.7
Okumura, T.8
Testa, J.R.9
Kohgo, Y.10
-
26
-
-
0035476803
-
The tyrosine kinase inhibitor ZD1839 ('Iressa') inhibits HER2-driven signaling and suppresses the growth of HER2-overexpressing tumor cells
-
Moasser MM, Basso A, Averbunch SD and Rosen N: The tyrosine kinase inhibitor ZD1839 ('Iressa') inhibits HER2-driven signaling and suppresses the growth of HER2-overexpressing tumor cells. Cancer Res 61: 7184-7188, 2001.
-
(2001)
Cancer Res
, vol.61
, pp. 7184-7188
-
-
Moasser, M.M.1
Basso, A.2
Averbunch, S.D.3
Rosen, N.4
-
27
-
-
13244251056
-
Differential radiosensitisation by ZD1839 (Iressa), a highly selective epidermal growth factor receptor tyrosine kinase inhibitor in two related bladder cancer cell lines
-
Maddineni SB, Sangar VK, Hendry JH, Margison GP and Clake NW: Differential radiosensitisation by ZD1839 (Iressa), a highly selective epidermal growth factor receptor tyrosine kinase inhibitor in two related bladder cancer cell lines. Br J Cancer 92: 125-130, 2005.
-
(2005)
Br J Cancer
, vol.92
, pp. 125-130
-
-
Maddineni, S.B.1
Sangar, V.K.2
Hendry, J.H.3
Margison, G.P.4
Clake, N.W.5
-
28
-
-
0036304685
-
Local recurrence in head and neck cancer: Relationship to radiation resistance and signal transduction
-
Gupta AK, McKenna WG, Weber CN, Feldman MD, Goldmith JD, Mick R, Machtay M, Rosenthal DI, Bakanauskas VJ, Cerniglia GJ, Bernhard EJ, Weber RS and Muschel RJ: Local recurrence in head and neck cancer: relationship to radiation resistance and signal transduction. Clin Cancer Res 8: 885-892, 2002.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 885-892
-
-
Gupta, A.K.1
McKenna, W.G.2
Weber, C.N.3
Feldman, M.D.4
Goldmith, J.D.5
Mick, R.6
Machtay, M.7
Rosenthal, D.I.8
Bakanauskas, V.J.9
Cerniglia, G.J.10
Bernhard, E.J.11
Weber, R.S.12
Muschel, R.J.13
-
29
-
-
0344430039
-
Time and dose-dependent radiosensitization of the glioblastoma multiple U251 cells by the EGF receptor tyrosine kinase inhibitor ZD1839 ('Iressa')
-
Stea B, Falsey R, Kislin K, Patel J, Glanzberg H, Carey S, Ambrad AA, Meuillet EJ and Martinez JD: Time and dose-dependent radiosensitization of the glioblastoma multiple U251 cells by the EGF receptor tyrosine kinase inhibitor ZD1839 ('Iressa'). Cancer Lett 202: 43-51, 2003.
-
(2003)
Cancer Lett
, vol.202
, pp. 43-51
-
-
Stea, B.1
Falsey, R.2
Kislin, K.3
Patel, J.4
Glanzberg, H.5
Carey, S.6
Ambrad, A.A.7
Meuillet, E.J.8
Martinez, J.D.9
-
30
-
-
85047696958
-
ZD1839 ('Iressa'), a specific oral epidermal growth factor receptor-tyrosine kinase inhibitor, potentiates radiotherapy in a human colorectal cancer xenograft model
-
Williams KJ, Telfer BA, Stratford IJ and Wedge SR: ZD1839 ('Iressa'), a specific oral epidermal growth factor receptor-tyrosine kinase inhibitor, potentiates radiotherapy in a human colorectal cancer xenograft model. Br J Cancer 86: 1157-1161, 2002.
-
(2002)
Br J Cancer
, vol.86
, pp. 1157-1161
-
-
Williams, K.J.1
Telfer, B.A.2
Stratford, I.J.3
Wedge, S.R.4
-
31
-
-
0036681995
-
Modulation of radiation response and tumor-induced angiogenesis after epidermal growth factor receptor inhibition by ZD1839 (Iressa)
-
Huang SM, Li J, Armstrong EA and Harari PM: Modulation of radiation response and tumor-induced angiogenesis after epidermal growth factor receptor inhibition by ZD1839 (Iressa). Cancer Res 62: 4300-4306, 2002.
-
(2002)
Cancer Res
, vol.62
, pp. 4300-4306
-
-
Huang, S.M.1
Li, J.2
Armstrong, E.A.3
Harari, P.M.4
-
32
-
-
0347928791
-
EGFR blockade with ZD1839 ('Iressa') potentiates the antitumor effects of single and multiple fractions of ionizing radiation in human A431 squamous cell carcinoma
-
Solomon B, Hagekyriakou J, Trivett MK, Stacker SA, McArthur GA and Cullinane C: EGFR blockade with ZD1839 ('Iressa') potentiates the antitumor effects of single and multiple fractions of ionizing radiation in human A431 squamous cell carcinoma. Int J Oncol Biol Phys 55: 713-723, 2003.
-
(2003)
Int J Oncol Biol Phys
, vol.55
, pp. 713-723
-
-
Solomon, B.1
Hagekyriakou, J.2
Trivett, M.K.3
Stacker, S.A.4
McArthur, G.A.5
Cullinane, C.6
-
33
-
-
0037276771
-
Expanding the therapeutic repertoire of epidermal growth factor receptor blockade: Radiosensitization
-
Gee JM and Nicholson RI: Expanding the therapeutic repertoire of epidermal growth factor receptor blockade: radiosensitization. Breast Cancer Res 5: 126-129, 2003.
-
(2003)
Breast Cancer Res
, vol.5
, pp. 126-129
-
-
Gee, J.M.1
Nicholson, R.I.2
-
34
-
-
0042399368
-
Targeting the phosphatidylinositol 3-kinase/Akt pathway for enhancing breast cancer cells to radiotherapy
-
Liang K, Jin W, Knuefermann C, Schmidt M, Mills GB, Ang KK, Milas L and Fan Z: Targeting the phosphatidylinositol 3-kinase/Akt pathway for enhancing breast cancer cells to radiotherapy. Mol Cancer Ther 2: 353-360, 2003.
-
(2003)
Mol Cancer Ther
, vol.2
, pp. 353-360
-
-
Liang, K.1
Jin, W.2
Knuefermann, C.3
Schmidt, M.4
Mills, G.B.5
Ang, K.K.6
Milas, L.7
Fan, Z.8
-
35
-
-
0032719534
-
Inverse relationship between epidermal growth factor receptor expression and radiocurability of murine carcinomas
-
Akimoto T, Hunter NR, Buchmiller L, Mason K, Ang KK and Milas L: Inverse relationship between epidermal growth factor receptor expression and radiocurability of murine carcinomas. Clin Cancer Res 5: 2884-2890, 1999.
-
(1999)
Clin Cancer Res
, vol.5
, pp. 2884-2890
-
-
Akimoto, T.1
Hunter, N.R.2
Buchmiller, L.3
Mason, K.4
Ang, K.K.5
Milas, L.6
-
36
-
-
78650374980
-
Radiation-induced signal transduction pathways: DNA double-strand break repair and radiation-induced activation of EGFR
-
Hosoi Y: Radiation-induced signal transduction pathways: DNA double-strand break repair and radiation-induced activation of EGFR. Jpn J Cancer Clin 50: 1055-1060, 2004.
-
(2004)
Jpn J Cancer Clin
, vol.50
, pp. 1055-1060
-
-
Hosoi, Y.1
-
37
-
-
0029804116
-
Mechanism of activation of protein kinase B by insulin and IGF-1
-
Alessi DR, Andjelkovic M, Caudwell B, Cron P, Morrice N, Cohen P and Hemmings BA: Mechanism of activation of protein kinase B by insulin and IGF-1. EMBO J 15: 6541-6551, 1996.
-
(1996)
EMBO J
, vol.15
, pp. 6541-6551
-
-
Alessi, D.R.1
Andjelkovic, M.2
Caudwell, B.3
Cron, P.4
Morrice, N.5
Cohen, P.6
Hemmings, B.A.7
-
38
-
-
12644301164
-
3-Phosphoinositide-dependent protein kinase-1 (PDK1): Structural and functional homology with the Drosophila DSTPK61 kinase
-
Alessi DR, Deak M, Casamayor A, Caudwell FB, Morrice N, Norman DG, Gaffney P, Reese CB, MacDougall CN, Harbison D, Ashworth A and Bownes M: 3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase. Curr Biol 7: 776-789, 1997.
-
(1997)
Curr Biol
, vol.7
, pp. 776-789
-
-
Alessi, D.R.1
Deak, M.2
Casamayor, A.3
Caudwell, F.B.4
Morrice, N.5
Norman, D.G.6
Gaffney, P.7
Reese, C.B.8
MacDougall, C.N.9
Harbison, D.10
Ashworth, A.11
Bownes, M.12
-
39
-
-
0033551070
-
New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway
-
Cantley LC and Neel BG: New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway. Proc Natl Acad Sci USA 96: 4240-4245, 1999.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 4240-4245
-
-
Cantley, L.C.1
Neel, B.G.2
-
40
-
-
0035949699
-
AKT plays a central role in tumorigenesis
-
Testa JR and Bellacosa A: AKT plays a central role in tumorigenesis. Proc Natl Acad Sci USA 98: 10983-10985, 2001.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 10983-10985
-
-
Testa, J.R.1
Bellacosa, A.2
-
41
-
-
0030907987
-
PI3K: Downstream AKTion blocks apoptosis
-
Franke TF, Kaplan DR and Cantley LC: PI3K: downstream AKTion blocks apoptosis. Cell 88: 435-437, 1997.
-
(1997)
Cell
, vol.88
, pp. 435-437
-
-
Franke, T.F.1
Kaplan, D.R.2
Cantley, L.C.3
-
42
-
-
0032053709
-
Mechanisms and consequences of activation of protein kinase B/Akt
-
Downward J: Mechanisms and consequences of activation of protein kinase B/Akt. Curr Opin Cell Biol 10: 262-267, 1998.
-
(1998)
Curr Opin Cell Biol
, vol.10
, pp. 262-267
-
-
Downward, J.1
-
43
-
-
0035893560
-
Epidermal growth factor receptor (HER1) tyrosine kinase inhibitor ZD1839 (Iressa) inhibits HER2/neu (erbB2)-overexpressing breast cancer cells in vitro and in vivo
-
Moulder SL, Yakes FM, Muthuswamy SK, Bianco R, Simpson JF and Arteaga CL: Epidermal growth factor receptor (HER1) tyrosine kinase inhibitor ZD1839 (Iressa) inhibits HER2/neu (erbB2)-overexpressing breast cancer cells in vitro and in vivo. Cancer Res 61: 8887-8895, 2001. (Pubitemid 34013905)
-
(2001)
Cancer Research
, vol.61
, Issue.24
, pp. 8887-8895
-
-
Moulder, S.L.1
Yakes, F.M.2
Muthuswamy, S.K.3
Bianco, R.4
Simpson, J.F.5
Arteaga, C.L.6
-
44
-
-
0037388251
-
ZD1839, a specific epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, induces the formation of inactive EGFR/HER2 and EGFR/HER3 heterodimers and prevents heregulin signaling in HER2-overexpressing breast cancer cells
-
Anido J, Matar P, Albanell J, Guzman M, Rojo F, Arrbas J, Averbuch S and Baselga J: ZD1839, a specific epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, induces the formation of inactive EGFR/HER2 and EGFR/HER3 heterodimers and prevents heregulin signaling in HER2-overexpressing breast cancer cells. Clin Cancer Res 9: 1274-1283, 2003.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 1274-1283
-
-
Anido, J.1
Matar, P.2
Albanell, J.3
Guzman, M.4
Rojo, F.5
Arrbas, J.6
Averbuch, S.7
Baselga, J.8
-
45
-
-
0034600849
-
The ErbB signaling network: Receptor heterodimerization in development and cancer
-
Olayioye MA, Neve RM, Lane HA and Hynes NE: The ErbB signaling network: receptor heterodimerization in development and cancer. EMBO J 19: 3159-3167, 2000.
-
(2000)
EMBO J
, vol.19
, pp. 3159-3167
-
-
Olayioye, M.A.1
Neve, R.M.2
Lane, H.A.3
Hynes, N.E.4
|