Engineering human IL-18 with increased bioactivity and bioavailability

Cytokine

Volumn 34, Issue 1-2, 2006, Pages 114-124

  Swencki Underwood, Bethany ^a   Cunningham, Mark R ^a   Heavner, George A ^a   Blasie, Cheryl ^a   McCarthy, Stephen G ^a   Dougherty, Tara ^a   Brigham Burke, Mike ^a   Gunn, George R ^a   Goletz, Theresa J ^a   Snyder, Linda A ^b  

^a CENTOCOR INC   (United States)

^b Oncology Research   (United States)

Author keywords

Adjuvant; DNA vaccine; IL 18; IL 18 receptor

Indexed keywords

GAMMA INTERFERON; RECOMBINANT INTERLEUKIN 18;

ANTIGEN EXPRESSION; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG BIOAVAILABILITY; EMBRYO; HUMAN; HUMAN CELL; MAMMAL CELL; MOLECULAR DYNAMICS; MONONUCLEAR CELL; NUCLEOTIDE SEQUENCE; PLASMID; PREDICTION; PRIORITY JOURNAL; RECEPTOR BINDING; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; BASE SEQUENCE; CLONING, MOLECULAR; HUMANS; INTERFERON TYPE II; INTERLEUKIN-18; LEUKOCYTES, MONONUCLEAR; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PLASMIDS; PROTEIN ENGINEERING; PROTEIN STRUCTURE, TERTIARY; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TRANSFECTION; VACCINES, DNA; VARIATION (GENETICS);

MAMMALIA;

EID: 33744548704     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cyto.2006.04.004     Document Type: Article

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