-
1
-
-
33744462778
-
-
World Health Organisation.
-
World Health Organisation. 2005. http://www.who.int/en/.
-
(2005)
-
-
-
2
-
-
2342466734
-
Global prevalence of diabetes: Estimates for the year 2000 and projections for 2030
-
Wild, S. et al. 2004. Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care 27 : 1047 1053.
-
(2004)
Diabetes Care
, vol.27
, pp. 1047-1053
-
-
Wild, S.1
-
3
-
-
17044386953
-
Type 2 diabetes: Principles of pathogenesis and therapy
-
&
-
Stumvoll, M., B.J. Goldstein & T.W. Van Haeften. 2005. Type 2 diabetes: principles of pathogenesis and therapy. Lancet 365 : 1333 1346.
-
(2005)
Lancet
, vol.365
, pp. 1333-1346
-
-
Stumvoll, M.1
Goldstein, B.J.2
Van Haeften, T.W.3
-
4
-
-
1542573343
-
PPAR ligands for metabolic disorders
-
&
-
Etgen, G.H. & N. Mantlo. 2003. PPAR ligands for metabolic disorders. Curr. Top. Med. Chem. 3 : 1649 1661.
-
(2003)
Curr. Top. Med. Chem.
, vol.3
, pp. 1649-1661
-
-
Etgen, G.H.1
Mantlo, N.2
-
5
-
-
0030062325
-
The structure-activity relationship between peroxisome proliferator-activated receptor gamma agonism and the antihyperglycemic activity of thiazolidinediones
-
Willson, T.M. et al. 1996. The structure-activity relationship between peroxisome proliferator-activated receptor gamma agonism and the antihyperglycemic activity of thiazolidinediones. J. Med. Chem. 39 : 665 668.
-
(1996)
J. Med. Chem.
, vol.39
, pp. 665-668
-
-
Willson, T.M.1
-
6
-
-
1942518840
-
PPARs and the complex journey to obesity
-
&
-
Evans, R.M., G.D. Barish & Y.X. Wang. 2004. PPARs and the complex journey to obesity. Nat. Med. 10 : 355 361.
-
(2004)
Nat. Med.
, vol.10
, pp. 355-361
-
-
Evans, R.M.1
Barish, G.D.2
Wang, Y.X.3
-
7
-
-
0842263981
-
The biology of peroxisome proliferator-activated receptors: Relationship with lipid metabolism and insulin sensitivity
-
Ferre, P. 2004. The biology of peroxisome proliferator-activated receptors: relationship with lipid metabolism and insulin sensitivity. Diabetes 53 Suppl 1 S43 S50.
-
(2004)
Diabetes
, vol.53
, Issue.1
-
-
Ferre, P.1
-
9
-
-
21644436821
-
Peroxisome proliferator-activated receptor (PPAR)-alpha: A (PPAR)-alpha: A pharmacological target with a promising future
-
Van Raalte, D.H. et al. 2004. Peroxisome proliferator-activated receptor (PPAR)-alpha: a (PPAR)-alpha: a pharmacological target with a promising future. Pharm. Res. 21 : 1531 1538.
-
(2004)
Pharm. Res.
, vol.21
, pp. 1531-1538
-
-
Raalte, V.D.H.1
-
10
-
-
2542491213
-
Peroxisome proliferator-activated receptor gamma in diabetes and metabolism
-
&
-
Rangwala, S.M. & M.A. Lazar. 2004. Peroxisome proliferator-activated receptor gamma in diabetes and metabolism. Trends Pharmacol. Sci. 25 : 331 336.
-
(2004)
Trends Pharmacol. Sci.
, vol.25
, pp. 331-336
-
-
Rangwala, S.M.1
Lazar, M.A.2
-
11
-
-
0035851187
-
PPARgamma: A nuclear regulator of metabolism, differentiation, and cell growth
-
&
-
Rosen, E.D. & B.M. Spiegelman. 2001. PPARgamma: a nuclear regulator of metabolism, differentiation, and cell growth. J. Biol. Chem. 276 : 37731 37734.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 37731-37734
-
-
Rosen, E.D.1
Spiegelman, B.M.2
-
12
-
-
14744267131
-
PPARdelta: An incompletely known PPAR nuclear receptor
-
&
-
Fredenrich, A. & P.A. Grimaldi. 2005. PPARdelta: an incompletely known PPAR nuclear receptor. Diabetes Metab. 31 : 23 27.
-
(2005)
Diabetes Metab.
, vol.31
, pp. 23-27
-
-
Fredenrich, A.1
Grimaldi, P.A.2
-
13
-
-
0035942162
-
A selective peroxisome proliferator-activated receptor delta agonist promotes reverse cholesterol transport
-
Oliver, W.R. et al. 2001. A selective peroxisome proliferator-activated receptor delta agonist promotes reverse cholesterol transport. Proc. Natl. Acad. Sci.USA 98 : 5306 5311.
-
(2001)
Proc. Natl. Acad. Sci.USA
, vol.98
, pp. 5306-5311
-
-
Oliver, W.R.1
-
14
-
-
0028972025
-
15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma
-
Forman, B.M. et al. 1995. 15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma. Cell 83 : 803 812.
-
(1995)
Cell
, vol.83
, pp. 803-812
-
-
Forman, B.M.1
-
15
-
-
0028972026
-
A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation
-
Kliewer, S.A. et al. 1995. A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation. Cell 83 : 813 819.
-
(1995)
Cell
, vol.83
, pp. 813-819
-
-
Kliewer, S.A.1
-
16
-
-
0041321275
-
Oleylethanolamide regulates feeding and body weight through activation of the nuclear receptor PPAR-alpha
-
Fu, J. et al. 2003. Oleylethanolamide regulates feeding and body weight through activation of the nuclear receptor PPAR-alpha. Nature 425 : 90 93.
-
(2003)
Nature
, vol.425
, pp. 90-93
-
-
Fu, J.1
-
17
-
-
11244328917
-
The nuclear receptor peroxisome proliferator-activated receptor-alpha mediates the anti-inflammatory actions of palmitoylethanolamide
-
Lo Verme, J. et al. 2004. The nuclear receptor peroxisome proliferator-activated receptor-alpha mediates the anti-inflammatory actions of palmitoylethanolamide. Mol. Pharmacol. 67 : 15 19.
-
(2004)
Mol. Pharmacol.
, vol.67
, pp. 15-19
-
-
Verme, L.J.1
-
18
-
-
33744459134
-
-
& Martin Dunitz Ltd. Taylor & Francis, London.
-
English, P. & G. Williams. 2001. Type 2 diabetes. Martin Dunitz Ltd. Taylor & Francis, London.
-
(2001)
Type 2 Diabetes
-
-
English, P.1
Williams, G.2
-
19
-
-
0037075146
-
Novel tricyclic-α-alkyloxyphenylpropionic acids: Dual PPARalpha/gamma agonists with hypolipidemic and antidiabetic activity
-
Sauerberg, P. et al. 2002. Novel tricyclic-α- alkyloxyphenylpropionic acids: dual PPARalpha/gamma agonists with hypolipidemic and antidiabetic activity. J. Med. Chem. 45 : 789 804.
-
(2002)
J. Med. Chem.
, vol.45
, pp. 789-804
-
-
Sauerberg, P.1
-
20
-
-
18744385217
-
Design and synthesis of novel PPARalpha/gamma/delta triple activators using a known PPARalpha/gamma dual activator as structural template
-
Mogensen, J.P. et al. 2003. Design and synthesis of novel PPARalpha/gamma/delta triple activators using a known PPARalpha/gamma dual activator as structural template. Bioorg. Med. Chem. Lett. 13 : 257 260.
-
(2003)
Bioorg. Med. Chem. Lett.
, vol.13
, pp. 257-260
-
-
Mogensen, J.P.1
-
21
-
-
0035797363
-
(-)3-[4-[2-(Phenoxazin-10-yl)ethoxy]phenyl]-2-ethoxypropanoic acid [(-)DRF 2725]: A dual PPAR agonist with potent antihyperglycemic and lipid modulating activity
-
Lohray, B.B. et al. 2001. (-)3-[4-[2-(Phenoxazin-10-yl)ethoxy]phenyl]-2- ethoxypropanoic acid [(-)DRF 2725]: a dual PPAR agonist with potent antihyperglycemic and lipid modulating activity. J. Med. Chem. 44 : 2675 2678.
-
(2001)
J. Med. Chem.
, vol.44
, pp. 2675-2678
-
-
Lohray, B.B.1
-
22
-
-
0242299587
-
Large dimeric ligands with favorable pharmacokinetic properties and peroxisome proliferator-activated receptor agonist activity in vitro and in vivo
-
Sauerberg, P. et al. 2003. Large dimeric ligands with favorable pharmacokinetic properties and peroxisome proliferator-activated receptor agonist activity in vitro and in vivo. J. Med. Chem. 46 : 4883 4894.
-
(2003)
J. Med. Chem.
, vol.46
, pp. 4883-4894
-
-
Sauerberg, P.1
-
23
-
-
13944262810
-
Structure-activity relationships of dimeric PPAR agonists
-
Sauerberg, P. et al. 2005. Structure-activity relationships of dimeric PPAR agonists. Bioorg. Med. Chem. Lett. 15 : 1497 1500.
-
(2005)
Bioorg. Med. Chem. Lett.
, vol.15
, pp. 1497-1500
-
-
Sauerberg, P.1
|