메뉴 건너뛰기




Volumn 74, Issue 6, 2006, Pages 3305-3313

Borrelia burgdorferi lacking BBK32, a fibronectin-binding protein, retains full pathogenicity

Author keywords

[No Author keywords available]

Indexed keywords

BBK32 PROTEIN; FIBRONECTIN BINDING PROTEIN; UNCLASSIFIED DRUG;

EID: 33646950247     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.02035-05     Document Type: Article
Times cited : (83)

References (61)
  • 1
    • 0032919853 scopus 로고    scopus 로고
    • The immunoglobulin (IgG) antibody response to OspA and OspB correlates with severe and prolonged Lyme arthritis and the IgG response to P35 correlates with mild and brief arthritis
    • Akin, E., G. L. McHugh, R. A. Flavell, E. Fikrig, and A. C. Steere. 1999. The immunoglobulin (IgG) antibody response to OspA and OspB correlates with severe and prolonged Lyme arthritis and the IgG response to P35 correlates with mild and brief arthritis. Infect. Immun. 67:173-181.
    • (1999) Infect. Immun. , vol.67 , pp. 173-181
    • Akin, E.1    McHugh, G.L.2    Flavell, R.A.3    Fikrig, E.4    Steere, A.C.5
  • 4
    • 0141756140 scopus 로고    scopus 로고
    • Bacterial pathogenesis: Exploiting cellular adherence
    • Boyle, E. C., and B. B. Finlay. 2003. Bacterial pathogenesis: exploiting cellular adherence. Curr. Opin. Cell Biol. 15:633-639.
    • (2003) Curr. Opin. Cell Biol. , vol.15 , pp. 633-639
    • Boyle, E.C.1    Finlay, B.B.2
  • 5
    • 0038104769 scopus 로고    scopus 로고
    • Global analysis of Borrelia burgdorferi genes regulated by mammalian host-specific signals
    • Brooks, C. S., P. S. Hefty, S. E. Jolliff, and D. R. Akins. 2003. Global analysis of Borrelia burgdorferi genes regulated by mammalian host-specific signals. Infect. Immun. 71:3371-3383.
    • (2003) Infect. Immun. , vol.71 , pp. 3371-3383
    • Brooks, C.S.1    Hefty, P.S.2    Jolliff, S.E.3    Akins, D.R.4
  • 6
    • 18844363955 scopus 로고    scopus 로고
    • Multicomponent Lyme vaccine: Three is not a crowd
    • Brown, E. L., J. H. Kim, E. S. Reisenbichler, and M. Hook. 2005. Multicomponent Lyme vaccine: three is not a crowd. Vaccine 23:3687-3696.
    • (2005) Vaccine , vol.23 , pp. 3687-3696
    • Brown, E.L.1    Kim, J.H.2    Reisenbichler, E.S.3    Hook, M.4
  • 8
    • 23344436798 scopus 로고    scopus 로고
    • Borrelia burgdorferi rel is responsible for generation of guanosine-3′-diphosphate-5′-triphosphate and growth control
    • Bugrysheva, J. V., A. V. Bryksin, H. P. Godfrey, and F. C. Cabello. 2005. Borrelia burgdorferi rel is responsible for generation of guanosine-3′- diphosphate-5′-triphosphate and growth control. Infect. Immun. 73:4972-4981.
    • (2005) Infect. Immun. , vol.73 , pp. 4972-4981
    • Bugrysheva, J.V.1    Bryksin, A.V.2    Godfrey, H.P.3    Cabello, F.C.4
  • 10
    • 7044233312 scopus 로고    scopus 로고
    • RpoS is not central to the general stress response in Borrelia burgdorferi but does control expression of one or more essential virulence determinants
    • Caimano, M. J., C. H. Eggers, K. R. Hazlett, and J. D. Radolf. 2004. RpoS is not central to the general stress response in Borrelia burgdorferi but does control expression of one or more essential virulence determinants. Infect. Immun. 72:6433-6445.
    • (2004) Infect. Immun. , vol.72 , pp. 6433-6445
    • Caimano, M.J.1    Eggers, C.H.2    Hazlett, K.R.3    Radolf, J.D.4
  • 12
    • 0033233457 scopus 로고    scopus 로고
    • Characterization of a candidate Borrelia burgdorferi beta3-chain integrin ligand identified using a phage display library
    • Coburn, J., W. Chege, L. Magoun, S. C. Bodary, and J. M. Leong. 1999. Characterization of a candidate Borrelia burgdorferi beta3-chain integrin ligand identified using a phage display library. Mol. Microbiol. 34:926-940.
    • (1999) Mol. Microbiol. , vol.34 , pp. 926-940
    • Coburn, J.1    Chege, W.2    Magoun, L.3    Bodary, S.C.4    Leong, J.M.5
  • 13
    • 0038809086 scopus 로고    scopus 로고
    • Targeted mutation of the outer membrane protein P66 disrupts attachment of the Lyme disease agent, Borrelia burgdorferi, to integrin alphavbeta3
    • Coburn, J., and C. Cugini. 2003. Targeted mutation of the outer membrane protein P66 disrupts attachment of the Lyme disease agent, Borrelia burgdorferi, to integrin alphavbeta3. Proc. Natl. Acad. Sci. USA 100:7301-7306.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 7301-7306
    • Coburn, J.1    Cugini, C.2
  • 14
    • 23844515087 scopus 로고    scopus 로고
    • Solving a sticky problem: New genetic approaches to host cell adhesion by the Lyme disease spirochete
    • Coburn, J., J. R. Fischer, and J. M. Leong. 2005. Solving a sticky problem: new genetic approaches to host cell adhesion by the Lyme disease spirochete. Mol. Microbiol. 57:1182-1195.
    • (2005) Mol. Microbiol. , vol.57 , pp. 1182-1195
    • Coburn, J.1    Fischer, J.R.2    Leong, J.M.3
  • 15
    • 0030025949 scopus 로고    scopus 로고
    • Borrelia burgdorferi OspA is an arthropod-specific transmission-blocking Lyme disease vaccine
    • de Silva, A. M., S. R. Telford, L. R. Brunet, S. W. Barthold, and E. Fikrig. 1996. Borrelia burgdorferi OspA is an arthropod-specific transmission-blocking Lyme disease vaccine. J. Exp. Med. 183:271-275.
    • (1996) J. Exp. Med. , vol.183 , pp. 271-275
    • De Silva, A.M.1    Telford, S.R.2    Brunet, L.R.3    Barthold, S.W.4    Fikrig, E.5
  • 16
    • 0034060506 scopus 로고    scopus 로고
    • Altered stationary-phase response in a Borrelia burgdorferi rpoS mutant
    • Elias, A. F., J. L. Bono, J. A. Carroll, P. Stewart, K. Tilly, and P. Rosa. 2000. Altered stationary-phase response in a Borrelia burgdorferi rpoS mutant. J. Bacteriol. 182:2909-2918.
    • (2000) J. Bacteriol. , vol.182 , pp. 2909-2918
    • Elias, A.F.1    Bono, J.L.2    Carroll, J.A.3    Stewart, P.4    Tilly, K.5    Rosa, P.6
  • 17
    • 0030983397 scopus 로고    scopus 로고
    • Borrelia burgdorferi P35 and P37 proteins, expressed in vivo, elicit protective immunity
    • Fikrig, E., S. W. Barthold, W. Sun, W. Feng, S. R. Telford, and R. A. Flavell. 1997. Borrelia burgdorferi P35 and P37 proteins, expressed in vivo, elicit protective immunity. Immunity 6:531-539.
    • (1997) Immunity , vol.6 , pp. 531-539
    • Fikrig, E.1    Barthold, S.W.2    Sun, W.3    Feng, W.4    Telford, S.R.5    Flavell, R.A.6
  • 18
    • 0034657179 scopus 로고    scopus 로고
    • Arthropod- and host-specific Borrelia burgdorferi bbk32 expression and the inhibition of spirochete transmission
    • Fikrig, E., W. Feng, S. W. Barthold, S. R. Telford, and R. A. Flavell. 2000. Arthropod- and host-specific Borrelia burgdorferi bbk32 expression and the inhibition of spirochete transmission. J. Immunol. 164:5344-5351.
    • (2000) J. Immunol. , vol.164 , pp. 5344-5351
    • Fikrig, E.1    Feng, W.2    Barthold, S.W.3    Telford, S.R.4    Flavell, R.A.5
  • 19
    • 0030790687 scopus 로고    scopus 로고
    • Common themes in microbial pathogenicity revisited
    • Finlay, B. B., and S. Falkow. 1997. Common themes in microbial pathogenicity revisited. Microbiol. Mol. Biol. Rev. 61:136-169.
    • (1997) Microbiol. Mol. Biol. Rev. , vol.61 , pp. 136-169
    • Finlay, B.B.1    Falkow, S.2
  • 20
    • 29644446929 scopus 로고    scopus 로고
    • Fibronectin binding protein BBK32 of the Lyme disease spirochete promotes bacterial attachment to glycosaminoglycans
    • Fischer, J. R., K. T. LeBlanc, and J. M. Leong. 2006. Fibronectin binding protein BBK32 of the Lyme disease spirochete promotes bacterial attachment to glycosaminoglycans. Infect. Immun. 74:435-441.
    • (2006) Infect. Immun. , vol.74 , pp. 435-441
    • Fischer, J.R.1    LeBlanc, K.T.2    Leong, J.M.3
  • 21
    • 0038132181 scopus 로고    scopus 로고
    • Decorinbinding proteins A and B confer distinct mammalian cell type-specific attachment by Borrelia burgdorferi, the Lyme disease spirochete
    • Fischer, J. R., N. Parveen, L. Magoun, and J. M. Leong. 2003. Decorinbinding proteins A and B confer distinct mammalian cell type-specific attachment by Borrelia burgdorferi, the Lyme disease spirochete. Proc. Natl. Acad. Sci. USA 100:7307-7312.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 7307-7312
    • Fischer, J.R.1    Parveen, N.2    Magoun, L.3    Leong, J.M.4
  • 22
    • 17044399341 scopus 로고    scopus 로고
    • Borrelia burgdorferi sigma54 is required for mammalian infection and vector transmission but not for tick colonization
    • Fisher, M. A., D. Grimm, A. K. Henion, A. F. Elias, P. E. Stewart, P. A. Rosa, and F. C. Gherardini. 2005. Borrelia burgdorferi sigma54 is required for mammalian infection and vector transmission but not for tick colonization. Proc. Natl. Acad. Sci. USA 102:5162-5167.
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 5162-5167
    • Fisher, M.A.1    Grimm, D.2    Henion, A.K.3    Elias, A.F.4    Stewart, P.E.5    Rosa, P.A.6    Gherardini, F.C.7
  • 27
    • 0242416998 scopus 로고    scopus 로고
    • Expression of a luxS gene is not required for Borrelia burgdorferi infection of mice via needle inoculation
    • Hubner, A., A. T. Revel, D. M. Nolen, K. E. Hagman, and M. V. Norgard. 2003. Expression of a luxS gene is not required for Borrelia burgdorferi infection of mice via needle inoculation. Infect. Immun. 71:2892-2896.
    • (2003) Infect. Immun. , vol.71 , pp. 2892-2896
    • Hubner, A.1    Revel, A.T.2    Nolen, D.M.3    Hagman, K.E.4    Norgard, M.V.5
  • 29
    • 0037099692 scopus 로고    scopus 로고
    • Molecular adaptation of Borrelia burgdorferi in the murine host
    • Liang, F. T., F. K. Nelson, and E. Fikrig. 2002. Molecular adaptation of Borrelia burgdorferi in the murine host. J. Exp. Med. 196:275-280.
    • (2002) J. Exp. Med. , vol.196 , pp. 275-280
    • Liang, F.T.1    Nelson, F.K.2    Fikrig, E.3
  • 30
    • 0030048119 scopus 로고    scopus 로고
    • Direct demonstration of antigenic substitution of Borrelia burgdorferi ex vivo: Exploration of the paradox of the early immune response to outer surface proteins A and C in Lyme disease
    • Montgomery, R. R., S. E. Malawista, K. J. Feen, and L. K. Bockenstedt. 1996. Direct demonstration of antigenic substitution of Borrelia burgdorferi ex vivo: exploration of the paradox of the early immune response to outer surface proteins A and C in Lyme disease. J. Exp. Med. 183:261-269.
    • (1996) J. Exp. Med. , vol.183 , pp. 261-269
    • Montgomery, R.R.1    Malawista, S.E.2    Feen, K.J.3    Bockenstedt, L.K.4
  • 36
    • 1642336137 scopus 로고    scopus 로고
    • Pleiotropic effects of inactivating a carboxyl-terminal protease, CtpA, in Borrelia burgdorferi
    • Ostberg, Y., J. A. Carroll, M. Pinne, J. G. Krum, P. Rosa, and S. Bergstrom. 2004. Pleiotropic effects of inactivating a carboxyl-terminal protease, CtpA, in Borrelia burgdorferi. J. Bacteriol. 186:2074-2084.
    • (2004) J. Bacteriol. , vol.186 , pp. 2074-2084
    • Ostberg, Y.1    Carroll, J.A.2    Pinne, M.3    Krum, J.G.4    Rosa, P.5    Bergstrom, S.6
  • 37
    • 0036947229 scopus 로고    scopus 로고
    • Elimination of channel-forming activity by insertional inactivation of the p13 gene in Borrelia burgdorferi
    • Ostberg, Y., M. Pinne, R. Benz, P. Rosa, and S. Bergstrom. 2002. Elimination of channel-forming activity by insertional inactivation of the p13 gene in Borrelia burgdorferi. J. Bacteriol. 184:6811-6819.
    • (2002) J. Bacteriol. , vol.184 , pp. 6811-6819
    • Ostberg, Y.1    Pinne, M.2    Benz, R.3    Rosa, P.4    Bergstrom, S.5
  • 40
    • 0034096379 scopus 로고    scopus 로고
    • Identification of a candidate glycosaminoglycan-binding adhesin of the Lyme disease spirochete Borrelia burgdorferi
    • Pärveen, N., and J. M. Leong. 2000. Identification of a candidate glycosaminoglycan-binding adhesin of the Lyme disease spirochete Borrelia burgdorferi. Mol. Microbiol. 35:1220-1234.
    • (2000) Mol. Microbiol. , vol.35 , pp. 1220-1234
    • Pärveen, N.1    Leong, J.M.2
  • 41
    • 0031769859 scopus 로고    scopus 로고
    • Identification of a 47 kDa fibronectin-binding protein expressed by Borrelia burgdorferi isolate B31
    • Probert, W. S., and B. J. Johnson. 1998. Identification of a 47 kDa fibronectin-binding protein expressed by Borrelia burgdorferi isolate B31. Mol. Microbiol. 30:1003-1015.
    • (1998) Mol. Microbiol. , vol.30 , pp. 1003-1015
    • Probert, W.S.1    Johnson, B.J.2
  • 42
    • 0035007253 scopus 로고    scopus 로고
    • Mapping the ligand-binding region of Borrelia burgdorferi fibronectin-binding protein BBK32
    • Probert, W. S., J. H. Kim, M. Hook, and B. J. Johnson. 2001. Mapping the ligand-binding region of Borrelia burgdorferi fibronectin-binding protein BBK32. Infect. Immun. 69:4129-4133.
    • (2001) Infect. Immun. , vol.69 , pp. 4129-4133
    • Probert, W.S.1    Kim, J.H.2    Hook, M.3    Johnson, B.J.4
  • 43
    • 0034610332 scopus 로고    scopus 로고
    • Correlation between plasmid content and infectivity in Borrelia burgdorferi
    • Purser, J. E., and S. J. Norris. 2000. Correlation between plasmid content and infectivity in Borrelia burgdorferi. Proc. Natl. Acad. Sci. USA 97:13865-13870.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 13865-13870
    • Purser, J.E.1    Norris, S.J.2
  • 46
    • 0037022354 scopus 로고    scopus 로고
    • DNA microarray analysis of differential gene expression in Borrelia burgdorferi, the Lyme disease spirochete
    • Revel, A. T., A. M. Talaat, and M. V. Norgard. 2002. DNA microarray analysis of differential gene expression in Borrelia burgdorferi, the Lyme disease spirochete. Proc. Natl. Acad. Sci. USA 99:1562-1567.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 1562-1567
    • Revel, A.T.1    Talaat, A.M.2    Norgard, M.V.3
  • 47
    • 13444293534 scopus 로고    scopus 로고
    • The burgeoning molecular genetics of the Lyme disease spirochaete
    • Rosa, P. A., K. Tilly, and P. E. Stewart. 2005. The burgeoning molecular genetics of the Lyme disease spirochaete. Nat. Rev. Microbiol. 3:129-143.
    • (2005) Nat. Rev. Microbiol. , vol.3 , pp. 129-143
    • Rosa, P.A.1    Tilly, K.2    Stewart, P.E.3
  • 48
    • 0029200874 scopus 로고
    • Electro transformation of the spirochete Borrelia burgdorferi
    • J. A. Nickioff (ed.). Humana Press, Totowa, N.J.
    • Samuels, D. S. 1995. Electro transformation of the spirochete Borrelia burgdorferi, p. 253-259. In J. A. Nickioff (ed.), Electroporation protocols for microorganisms, vol. 47. Humana Press, Totowa, N.J.
    • (1995) Electroporation Protocols for Microorganisms , vol.47 , pp. 253-259
    • Samuels, D.S.1
  • 49
    • 0028109046 scopus 로고
    • Genetic transformation of the Lyme disease agent Borrelia burgdorferi with coumarin-resistant gyrB
    • Samuels, D. S., K. E. Mach, and C. F. Garon. 1994. Genetic transformation of the Lyme disease agent Borrelia burgdorferi with coumarin-resistant gyrB. J. Bacteriol. 176:6045-6049.
    • (1994) J. Bacteriol. , vol.176 , pp. 6045-6049
    • Samuels, D.S.1    Mach, K.E.2    Garon, C.F.3
  • 50
    • 0033984294 scopus 로고    scopus 로고
    • Temporal changes in outer surface proteins A and C of the Lyme disease-associated spirochete, Borrelia burgdorferi, during the chain of infection in ticks and mice
    • Schwan, T. G., and J. Piesman. 2000. Temporal changes in outer surface proteins A and C of the Lyme disease-associated spirochete, Borrelia burgdorferi, during the chain of infection in ticks and mice. J. Clin. Microbiol. 38:382-388.
    • (2000) J. Clin. Microbiol. , vol.38 , pp. 382-388
    • Schwan, T.G.1    Piesman, J.2
  • 51
    • 0028926240 scopus 로고
    • Induction of an outer surface protein on Borrelia burgdorferi during tick feeding
    • Schwan, T. G., J. Piesman, W. T. Golde, M. C. Dolan, and P. A. Rosa. 1995. Induction of an outer surface protein on Borrelia burgdorferi during tick feeding. Proc. Natl. Acad. Sci. USA 92:2909-2913.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 2909-2913
    • Schwan, T.G.1    Piesman, J.2    Golde, W.T.3    Dolan, M.C.4    Rosa, P.A.5
  • 53
    • 0028641494 scopus 로고
    • The emergence of Lyme disease and human babesiosis in a changing environment
    • Spielman, A. 1994. The emergence of Lyme disease and human babesiosis in a changing environment. Ann. N. Y. Acad. Sci. 740:145-156.
    • (1994) Ann. N. Y. Acad. Sci. , vol.740 , pp. 145-156
    • Spielman, A.1
  • 56
    • 3543070597 scopus 로고    scopus 로고
    • Infectious cycle analysis of a Borrelia burgdorferi mutant defective in transport of chitobiose, a tick cuticle component
    • Tilly, K., D. Grimm, D. M. Bueschel, J. G. Krum, and P. Rosa. 2004. Infectious cycle analysis of a Borrelia burgdorferi mutant defective in transport of chitobiose, a tick cuticle component. Vector Borne Zoonotic Dis. 4:159-168.
    • (2004) Vector Borne Zoonotic Dis. , vol.4 , pp. 159-168
    • Tilly, K.1    Grimm, D.2    Bueschel, D.M.3    Krum, J.G.4    Rosa, P.5
  • 57
    • 4544350205 scopus 로고    scopus 로고
    • Combined effects of blood and temperature shift on Borrelia burgdorferi gene expression as determined by whole genome DNA array
    • Tokarz, R., J. M. Anderton, L. I. Katona, and J. L. Benach. 2004. Combined effects of blood and temperature shift on Borrelia burgdorferi gene expression as determined by whole genome DNA array. Infect. Immun. 72:5419-5432.
    • (2004) Infect. Immun. , vol.72 , pp. 5419-5432
    • Tokarz, R.1    Anderton, J.M.2    Katona, L.I.3    Benach, J.L.4
  • 59
    • 27744483876 scopus 로고    scopus 로고
    • Association of linear plasmid 28-1 with an arthritic phenotype of Borrelia burgdorferi
    • Xu, Q., S. V. Seemanapalli, L. Lomax, K. McShan, X. Li, E. Fikrig, and F. T. Liang. 2005. Association of linear plasmid 28-1 with an arthritic phenotype of Borrelia burgdorferi. Infect. Immun. 73:7208-7215.
    • (2005) Infect. Immun. , vol.73 , pp. 7208-7215
    • Xu, Q.1    Seemanapalli, S.V.2    Lomax, L.3    McShan, K.4    Li, X.5    Fikrig, E.6    Liang, F.T.7
  • 60
    • 0141814623 scopus 로고    scopus 로고
    • The response regulator Rrp2 is essential for the expression of major membrane lipoproteins in Borrelia burgdorferi
    • Yang, X. F., S. M. Alani, and M. V. Norgard. 2003. The response regulator Rrp2 is essential for the expression of major membrane lipoproteins in Borrelia burgdorferi. Proc. Natl. Acad. Sci. USA 100:11001-11006.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 11001-11006
    • Yang, X.F.1    Alani, S.M.2    Norgard, M.V.3
  • 61
    • 1542283705 scopus 로고    scopus 로고
    • Essential role for OspA/B in the life cycle of the Lyme disease spirochete
    • Yang, X. F., U. Pal, S. M. Alani, E. Fikrig, and M. V. Norgard. 2004. Essential role for OspA/B in the life cycle of the Lyme disease spirochete. J. Exp. Med. 199:641-648.
    • (2004) J. Exp. Med. , vol.199 , pp. 641-648
    • Yang, X.F.1    Pal, U.2    Alani, S.M.3    Fikrig, E.4    Norgard, M.V.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.