메뉴 건너뛰기




Volumn 26, Issue 11, 2006, Pages 4041-4051

Insulin-like growth factor I controls a mutually exclusive association of RACK1 with protein phosphatase 2A and β1 integrin to promote cell migration

Author keywords

[No Author keywords available]

Indexed keywords

BETA1 INTEGRIN; ENZYME INHIBITOR; FIBRONECTIN; HYBRID PROTEIN; MATRIGEL; MUTANT PROTEIN; OKADAIC ACID; PHOSPHOPROTEIN PHOSPHATASE 2A; RACK1 PROTEIN; RECOMBINANT PROTEIN; REGULATOR PROTEIN; SCAFFOLD PROTEIN; SMALL INTERFERING RNA; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR; TRANSACTIVATOR PROTEIN; UNCLASSIFIED DRUG;

EID: 33646892664     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.01868-05     Document Type: Article
Times cited : (91)

References (43)
  • 1
    • 0034912159 scopus 로고    scopus 로고
    • Insulin-like growth factor axis during embryonic development
    • Allan, G. J., D. J. Flint, and K. Patel. 2001. Insulin-like growth factor axis during embryonic development. Reproduction 122:31-39.
    • (2001) Reproduction , vol.122 , pp. 31-39
    • Allan, G.J.1    Flint, D.J.2    Patel, K.3
  • 2
    • 22744449073 scopus 로고    scopus 로고
    • An Akt/beta-arrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behavior
    • Beaulieu, J. M., T. D. Sotnikova, S. Marion, R. J. Lefkowitz, R. R. Gainetdinov, and M. G. Caron. 2005. An Akt/beta-arrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behavior. Cell 122: 261-273.
    • (2005) Cell , vol.122 , pp. 261-273
    • Beaulieu, J.M.1    Sotnikova, T.D.2    Marion, S.3    Lefkowitz, R.J.4    Gainetdinov, R.R.5    Caron, M.G.6
  • 3
    • 0033664370 scopus 로고    scopus 로고
    • RACK1 is up-regulated in angiogenesis and human carcinomas
    • Berns, H., R. Humar, B. Hengerer, F. N. Kiefer, and E. J. Battegay. 2000. RACK1 is up-regulated in angiogenesis and human carcinomas. FASEB J. 14:2549-2558.
    • (2000) FASEB J. , vol.14 , pp. 2549-2558
    • Berns, H.1    Humar, R.2    Hengerer, B.3    Kiefer, F.N.4    Battegay, E.J.5
  • 4
    • 0037085442 scopus 로고    scopus 로고
    • Protein phosphatase 2A and protein kinase Calpha are physically associated and are involved in Pseudomonas aeruginosa-induced interleukin 6 production by mast cells
    • Boudreau, R. T., R. Garduno, and T. J. Lin. 2002. Protein phosphatase 2A and protein kinase Calpha are physically associated and are involved in Pseudomonas aeruginosa-induced interleukin 6 production by mast cells. J. Biol. Chem. 277:5322-5329.
    • (2002) J. Biol. Chem. , vol.277 , pp. 5322-5329
    • Boudreau, R.T.1    Garduno, R.2    Lin, T.J.3
  • 5
    • 0034996167 scopus 로고    scopus 로고
    • The WD protein Rack1 mediates protein kinase C and integrin-dependent cell migration
    • Buensuceso, C. S., D. Woodside, J. L. Huff, G. E. Plopper, and T. E. O'Toole. 2001. The WD protein Rack1 mediates protein kinase C and integrin-dependent cell migration. J. Cell Sci. 114:1691-1698.
    • (2001) J. Cell Sci. , vol.114 , pp. 1691-1698
    • Buensuceso, C.S.1    Woodside, D.2    Huff, J.L.3    Plopper, G.E.4    O'Toole, T.E.5
  • 6
    • 0031814131 scopus 로고    scopus 로고
    • RACK1, a receptor for activated C kinase and a homolog of the β subunit of G proteins, inhibits activity of Src tyrosine kinases and growth of NIH 3T3 cells
    • Chang, B. Y., K. B. Conroy, E. M. Machleder, and C. A. Cartwright. 1998. RACK1, a receptor for activated C kinase and a homolog of the β subunit of G proteins, inhibits activity of Src tyrosine kinases and growth of NIH 3T3 cells. Mol. Cell. Biol. 18:3245-3256.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 3245-3256
    • Chang, B.Y.1    Conroy, K.B.2    Machleder, E.M.3    Cartwright, C.A.4
  • 7
    • 15744397570 scopus 로고    scopus 로고
    • Dimerize RACK1 upon transformation with oncogenic ras
    • Chu, L. Y., Y. H. Chen, and N. N. Chuang. 2005. Dimerize RACK1 upon transformation with oncogenic ras. Biochem. Biophys. Res. Commun. 330: 474-482.
    • (2005) Biochem. Biophys. Res. Commun. , vol.330 , pp. 474-482
    • Chu, L.Y.1    Chen, Y.H.2    Chuang, N.N.3
  • 8
    • 0038071783 scopus 로고    scopus 로고
    • Minireview: Integral membrane proteins that function coordinately with the insulin-like growth factor I receptor to regulate intracellular signaling
    • Clemmons, D. R., and L. A. Maile. 2003. Minireview: integral membrane proteins that function coordinately with the insulin-like growth factor I receptor to regulate intracellular signaling. Endocrinology 144:1664-1670.
    • (2003) Endocrinology , vol.144 , pp. 1664-1670
    • Clemmons, D.R.1    Maile, L.A.2
  • 9
    • 0037329051 scopus 로고    scopus 로고
    • RACK1 regulates integrin-mediated adhesion, protrusion, and chemotactic cell migration via its Src-binding site
    • Cox, E. A., D. Bennin, A. T. Doan, T. O'Toole, and A. Huttenlocher. 2003. RACK1 regulates integrin-mediated adhesion, protrusion, and chemotactic cell migration via its Src-binding site. Mol. Biol. Cell 14:658-669.
    • (2003) Mol. Biol. Cell , vol.14 , pp. 658-669
    • Cox, E.A.1    Bennin, D.2    Doan, A.T.3    O'Toole, T.4    Huttenlocher, A.5
  • 10
    • 23044482717 scopus 로고    scopus 로고
    • Beta1A integrin expression is required for type 1 insulin-like growth factor receptor mitogenic and transforming activities and localization to focal contacts
    • Goel, H. L., M. Breen, J. Zhang, I. Das, S. Aznavoorian-Cheshire, N. M. Greenberg, A. Elgavish, and L. R. Languino. 2005. beta1A integrin expression is required for type 1 insulin-like growth factor receptor mitogenic and transforming activities and localization to focal contacts. Cancer Res. 65: 6692-6700.
    • (2005) Cancer Res. , vol.65 , pp. 6692-6700
    • Goel, H.L.1    Breen, M.2    Zhang, J.3    Das, I.4    Aznavoorian-Cheshire, S.5    Greenberg, N.M.6    Elgavish, A.7    Languino, L.R.8
  • 11
    • 3543127788 scopus 로고    scopus 로고
    • Selective modulation of type 1 insulin-like growth factor receptor signaling and functions by beta1 integrins
    • Goel, H. L., M. Fornaro, L. Moro, N. Teider, J. S. Rhim, M. King, and L. R. Languino. 2004. Selective modulation of type 1 insulin-like growth factor receptor signaling and functions by beta1 integrins. J. Cell Biol. 166:407-418.
    • (2004) J. Cell Biol. , vol.166 , pp. 407-418
    • Goel, H.L.1    Fornaro, M.2    Moro, L.3    Teider, N.4    Rhim, J.S.5    King, M.6    Languino, L.R.7
  • 12
    • 23144467910 scopus 로고    scopus 로고
    • An expanding role for mTOR in cancer
    • Guertin, D. A., and D. M. Sabatini. 2005. An expanding role for mTOR in cancer. Trends Mol. Med. 11:353-361.
    • (2005) Trends Mol. Med. , vol.11 , pp. 353-361
    • Guertin, D.A.1    Sabatini, D.M.2
  • 13
    • 0036070882 scopus 로고    scopus 로고
    • Ethanol induces gene expression via nuclear compartmentalization of receptor for activated C kinase 1
    • He, D. Y., A. J. Vagts, R. Yaka, and D. Ron. 2002. Ethanol induces gene expression via nuclear compartmentalization of receptor for activated C kinase 1. Mol. Pharmacol. 62:272-280.
    • (2002) Mol. Pharmacol. , vol.62 , pp. 272-280
    • He, D.Y.1    Vagts, A.J.2    Yaka, R.3    Ron, D.4
  • 14
    • 0036124703 scopus 로고    scopus 로고
    • RACK1, an insulin-like growth factor I (IGF-I) receptor-interacting protein, modulates IGF-I-dependent integrin signaling and promotes cell spreading and contact with extracellular matrix
    • Hermanto, U., C. S. Zong, W. Li, and L.-H. Wang. 2002. RACK1, an insulin-like growth factor I (IGF-I) receptor-interacting protein, modulates IGF-I-dependent integrin signaling and promotes cell spreading and contact with extracellular matrix. Mol. Cell. Biol. 22:2345-2365.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 2345-2365
    • Hermanto, U.1    Zong, C.S.2    Li, W.3    Wang, L.-H.4
  • 15
    • 0029883920 scopus 로고    scopus 로고
    • Mutational analysis of the mitogenic and transforming activities of the insulin-like growth factor I receptor
    • Hongo, A., C. D'Ambrosio, M. Miura, A. Morrione, and R. Baserga. 1996. Mutational analysis of the mitogenic and transforming activities of the insulin-like growth factor I receptor. Oncogene 12:1231-1238.
    • (1996) Oncogene , vol.12 , pp. 1231-1238
    • Hongo, A.1    D'Ambrosio, C.2    Miura, M.3    Morrione, A.4    Baserga, R.5
  • 16
    • 17044378112 scopus 로고    scopus 로고
    • Trap RACK1 with Ras to mobilize Src signaling at syndecan-2/p120-GAP upon transformation with oncogenic ras
    • Huang, J. W., C. L. Chen, and N. N. Chuang. 2005. Trap RACK1 with Ras to mobilize Src signaling at syndecan-2/p120-GAP upon transformation with oncogenic ras. Biochem. Biophys. Res. Commun. 330:1087-1094.
    • (2005) Biochem. Biophys. Res. Commun. , vol.330 , pp. 1087-1094
    • Huang, J.W.1    Chen, C.L.2    Chuang, N.N.3
  • 17
    • 0036170771 scopus 로고    scopus 로고
    • Integrin α2β1 promotes activation of protein phosphatase 2A and dephosphorylation of Akt and glycogen synthase kinase 3β
    • Ivaska, J., L. Nissinen, N. Immonen, J. E. Eriksson, V.-M. Kähäri, and J. Heino. 2002. Integrin α2β1 promotes activation of protein phosphatase 2A and dephosphorylation of Akt and glycogen synthase kinase 3β. Mol. Cell. Biol. 22:1352-1359.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 1352-1359
    • Ivaska, J.1    Nissinen, L.2    Immonen, N.3    Eriksson, J.E.4    Kähäri, V.-M.5    Heino, J.6
  • 18
    • 14844293473 scopus 로고    scopus 로고
    • RACK1-mediated integration of adhesion and insulin-like growth factor I (IGF-I) signaling and cell migration are defective in cells expressing an IGF-I receptor mutated at tyrosines 1250 and 1251
    • Kiely, P. A., M. Leahy, D. O'Gorman, and R. O'Connor. 2005. RACK1-mediated integration of adhesion and insulin-like growth factor I (IGF-I) signaling and cell migration are defective in cells expressing an IGF-I receptor mutated at tyrosines 1250 and 1251. J. Biol. Chem. 280:7624-7633.
    • (2005) J. Biol. Chem. , vol.280 , pp. 7624-7633
    • Kiely, P.A.1    Leahy, M.2    O'Gorman, D.3    O'Connor, R.4
  • 19
    • 0037151009 scopus 로고    scopus 로고
    • RACK1 is an insulin-like growth factor I (IGF-I) receptor-interacting protein that can regulate IGF-I-mediated Akt activation and protection from cell death
    • Kiely, P. A., A. Sant, and R. O'Connor. 2002. RACK1 is an insulin-like growth factor I (IGF-I) receptor-interacting protein that can regulate IGF-I-mediated Akt activation and protection from cell death. J. Biol. Chem. 277:22581-22589.
    • (2002) J. Biol. Chem. , vol.277 , pp. 22581-22589
    • Kiely, P.A.1    Sant, A.2    O'Connor, R.3
  • 20
    • 1342282948 scopus 로고    scopus 로고
    • Modulation of Thr phosphorylation of integrin beta1 during muscle differentiation
    • Kim, S. M., M. S. Kwon, C. S. Park, K. R. Choi, J. S. Chun, J. Ahn, and W. K. Song. 2004. Modulation of Thr phosphorylation of integrin beta1 during muscle differentiation. J. Biol. Chem. 279:7082-7090.
    • (2004) J. Biol. Chem. , vol.279 , pp. 7082-7090
    • Kim, S.M.1    Kwon, M.S.2    Park, C.S.3    Choi, K.R.4    Chun, J.S.5    Ahn, J.6    Song, W.K.7
  • 21
    • 0028957113 scopus 로고
    • Molecular and cellular aspects of the insulin-like growth factor I receptor
    • LeRoith, D., H. Werner, D. Beitner-Johnson, and C. T. Roberts, Jr. 1995. Molecular and cellular aspects of the insulin-like growth factor I receptor. Endocr. Rev. 16:143-163.
    • (1995) Endocr. Rev. , vol.16 , pp. 143-163
    • Leroith, D.1    Werner, H.2    Beitner-Johnson, D.3    Roberts Jr., C.T.4
  • 22
    • 0031893954 scopus 로고    scopus 로고
    • Rack1, a receptor for activated protein kinase C, interacts with integrin beta subunit
    • Liliental, J., and D. D. Chang. 1998. Rack1, a receptor for activated protein kinase C, interacts with integrin beta subunit. J. Biol. Chem. 273:2379-2383.
    • (1998) J. Biol. Chem. , vol.273 , pp. 2379-2383
    • Liliental, J.1    Chang, D.D.2
  • 23
    • 11144264646 scopus 로고    scopus 로고
    • Insulin-like growth factor I controls adhesion strength mediated by alpha5beta1 integrins in motile carcinoma cells
    • Lynch, L., P. I. Vodyanik, D. Boettiger, and M. A. Guvakova. 2005. Insulin-like growth factor I controls adhesion strength mediated by alpha5beta1 integrins in motile carcinoma cells. Mol. Biol. Cell 16:51-63.
    • (2005) Mol. Biol. Cell , vol.16 , pp. 51-63
    • Lynch, L.1    Vodyanik, P.I.2    Boettiger, D.3    Guvakova, M.A.4
  • 26
    • 21244493635 scopus 로고    scopus 로고
    • Treatment of hematologic malignancies and solid tumors by inhibiting IGF receptor signaling
    • Mitsiades, C. S., and N. Mitsiades. 2005. Treatment of hematologic malignancies and solid tumors by inhibiting IGF receptor signaling. Expert Rev. Anticancer Ther. 5:487-499.
    • (2005) Expert Rev. Anticancer Ther. , vol.5 , pp. 487-499
    • Mitsiades, C.S.1    Mitsiades, N.2
  • 27
    • 0035719947 scopus 로고    scopus 로고
    • Distinct and overlapping functions of insulin and IGF-I receptors
    • Nakae, J., Y. Kido, and D. Accili. 2001. Distinct and overlapping functions of insulin and IGF-I receptors. Endocr. Rev. 22:818-835.
    • (2001) Endocr. Rev. , vol.22 , pp. 818-835
    • Nakae, J.1    Kido, Y.2    Accili, D.3
  • 28
    • 9644268123 scopus 로고    scopus 로고
    • Mitotic dissociation of IQGAP1 from Rac-bound beta1-integrin is mediated by protein phosphatase 2A
    • Nakajima, E., K. Suzuki, and K. Takahashi. 2005. Mitotic dissociation of IQGAP1 from Rac-bound beta1-integrin is mediated by protein phosphatase 2A. Biochem. Biophys. Res. Commun. 326:249-253.
    • (2005) Biochem. Biophys. Res. Commun. , vol.326 , pp. 249-253
    • Nakajima, E.1    Suzuki, K.2    Takahashi, K.3
  • 29
    • 0031028245 scopus 로고    scopus 로고
    • Identification of domains of the insulin-like growth factor I receptor that are required for protection from apoptosis
    • O'Connor, R., A. Kauffmann-Zeh, Y. Liu, S. Lehar, G. I. Evan, R. Baserga, and W. A. Blattler. 1997. Identification of domains of the insulin-like growth factor I receptor that are required for protection from apoptosis. Mol. Cell. Biol. 17:427-435.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 427-435
    • O'Connor, R.1    Kauffmann-Zeh, A.2    Liu, Y.3    Lehar, S.4    Evan, G.I.5    Baserga, R.6    Blattler, W.A.7
  • 31
    • 18544377343 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-induced migration of multiple myeloma cells is associated with beta 1 integrin- and phosphatidylinositol 3-kinase-dependent PKC alpha activation
    • Podar, K., Y. T. Tai, B. K. Lin, R. P. Narsimhan, M. Sattler, T. Kijima, R. Salgia, D. Gupta, D. Chauhan, and K. C. Anderson. 2002. Vascular endothelial growth factor-induced migration of multiple myeloma cells is associated with beta 1 integrin- and phosphatidylinositol 3-kinase-dependent PKC alpha activation. J. Biol. Chem. 277:7875-7881.
    • (2002) J. Biol. Chem. , vol.277 , pp. 7875-7881
    • Podar, K.1    Tai, Y.T.2    Lin, B.K.3    Narsimhan, R.P.4    Sattler, M.5    Kijima, T.6    Salgia, R.7    Gupta, D.8    Chauhan, D.9    Anderson, K.C.10
  • 32
    • 0028036338 scopus 로고
    • Cloning of an intracellular receptor for protein kinase C: A homolog of the beta subunit of G proteins
    • Ron, D., C. H. Chen, J. Caldwell, L. Jamieson, E. Orr, and D. Mochly-Rosen. 1994. Cloning of an intracellular receptor for protein kinase C: a homolog of the beta subunit of G proteins. Proc. Natl. Acad. Sci. USA 91:839-843.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 839-843
    • Ron, D.1    Chen, C.H.2    Caldwell, J.3    Jamieson, L.4    Orr, E.5    Mochly-Rosen, D.6
  • 33
    • 0028805699 scopus 로고
    • C2 region-derived peptides inhibit translocation and function of beta protein kinase C in vivo
    • Ron, D., J. Luo, and D. Mochly-Rosen. 1995. C2 region-derived peptides inhibit translocation and function of beta protein kinase C in vivo. J. Biol. Chem. 270:24180-24187.
    • (1995) J. Biol. Chem. , vol.270 , pp. 24180-24187
    • Ron, D.1    Luo, J.2    Mochly-Rosen, D.3
  • 34
    • 13844312400 scopus 로고    scopus 로고
    • Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex
    • Sarbassov, D. D., D. A. Guertin, S. M. Ali, and D. M. Sabatini. 2005. Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex. Science 307:1098-1101.
    • (2005) Science , vol.307 , pp. 1098-1101
    • Sarbassov, D.D.1    Guertin, D.A.2    Ali, S.M.3    Sabatini, D.M.4
  • 35
    • 0028332092 scopus 로고
    • Effect of a null mutation of the insulin-like growth factor I receptor gene on growth and transformation of mouse embryo fibroblasts
    • Sell, C., G. Dumenil, C. Deveaud, M. Miura, D. Coppola, T. DeAngelis, R. Rubin, A. Efstratiadis, and R. Baserga. 1994. Effect of a null mutation of the insulin-like growth factor I receptor gene on growth and transformation of mouse embryo fibroblasts. Mol. Cell. Biol. 14:3604-3612.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 3604-3612
    • Sell, C.1    Dumenil, G.2    Deveaud, C.3    Miura, M.4    Coppola, D.5    DeAngelis, T.6    Rubin, R.7    Efstratiadis, A.8    Baserga, R.9
  • 36
    • 4744350970 scopus 로고    scopus 로고
    • Identification of the versatile scaffold protein RACK1 on the eukaryotic ribosome by cryo-EM
    • Sengupta, J., J. Nilsson, R. Gursky, C. M. Spahn, P. Nissen, and J. Frank. 2004. Identification of the versatile scaffold protein RACK1 on the eukaryotic ribosome by cryo-EM. Nat. Struct. Mol. Biol. 11:957-962.
    • (2004) Nat. Struct. Mol. Biol. , vol.11 , pp. 957-962
    • Sengupta, J.1    Nilsson, J.2    Gursky, R.3    Spahn, C.M.4    Nissen, P.5    Frank, J.6
  • 37
    • 18244377646 scopus 로고    scopus 로고
    • Requirement of protein phosphatase 2A for recruitment of IQGAP1 to Rac-bound betal integrin
    • Suzuki, K., Y. Chikamatsu, and K. Takahashi. 2005. Requirement of protein phosphatase 2A for recruitment of IQGAP1 to Rac-bound betal integrin. J. Cell. Physiol. 203:487-492.
    • (2005) J. Cell. Physiol. , vol.203 , pp. 487-492
    • Suzuki, K.1    Chikamatsu, Y.2    Takahashi, K.3
  • 38
    • 3142688531 scopus 로고    scopus 로고
    • Reduced expression of the regulatory a subunit of serine/threonine protein phosphatase 2A in human breast cancer MCF-7 cells
    • Suzuki, K., and K. Takahashi. 2003. Reduced expression of the regulatory A subunit of serine/threonine protein phosphatase 2A in human breast cancer MCF-7 cells. Int. J. Oncol. 23:1263-1268.
    • (2003) Int. J. Oncol. , vol.23 , pp. 1263-1268
    • Suzuki, K.1    Takahashi, K.2
  • 39
    • 3843150519 scopus 로고    scopus 로고
    • Spatial and temporal regulation of RACK1 function and N-methyl-o-aspartate receptor activity through WD40 motif-mediated dimerization
    • Thornton, C., K. C. Tang, K. Phamluong, K. Luong, A. Vagts, D. Nikanjam, R. Yaka, and D. Ron. 2004. Spatial and temporal regulation of RACK1 function and N-methyl-o-aspartate receptor activity through WD40 motif-mediated dimerization. J. Biol. Chem. 279:31357-31364.
    • (2004) J. Biol. Chem. , vol.279 , pp. 31357-31364
    • Thornton, C.1    Tang, K.C.2    Phamluong, K.3    Luong, K.4    Vagts, A.5    Nikanjam, D.6    Yaka, R.7    Ron, D.8
  • 40
    • 4544314719 scopus 로고    scopus 로고
    • Protein phosphatase 2A negatively regulates insulin's metabolic signaling pathway by inhibiting Akt (protein kinase B) activity in 3T3-L1 adipocytes
    • Ugi, S., T. Imamura, H. Maegawa, K. Egawa, T. Yoshizaki, K. Shi, T. Obata, Y. Ebina, A. Kashiwagi, and J. M. Olefsky. 2004. Protein phosphatase 2A negatively regulates insulin's metabolic signaling pathway by inhibiting Akt (protein kinase B) activity in 3T3-L1 adipocytes. Mol. Cell. Biol. 24:8778-8789.
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 8778-8789
    • Ugi, S.1    Imamura, T.2    Maegawa, H.3    Egawa, K.4    Yoshizaki, T.5    Shi, K.6    Obata, T.7    Ebina, Y.8    Kashiwagi, A.9    Olefsky, J.M.10
  • 41
    • 0036122481 scopus 로고    scopus 로고
    • Protein phosphatase 2A forms a molecular complex with She and regulates She tyrosine phosphorylation and downstream mitogenic signaling
    • Ugi, S., T. Imamura, W. Ricketts, and J. M. Olefsky. 2002. Protein phosphatase 2A forms a molecular complex with She and regulates She tyrosine phosphorylation and downstream mitogenic signaling. Mol. Cell. Biol. 22: 2375-2387.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 2375-2387
    • Ugi, S.1    Imamura, T.2    Ricketts, W.3    Olefsky, J.M.4
  • 42
    • 0036229695 scopus 로고    scopus 로고
    • Integrin regulation of growth factor receptors
    • Yamada, K. M., and S. Even-Ram. 2002. Integrin regulation of growth factor receptors. Nat. Cell Biol. 4:E75-E76.
    • (2002) Nat. Cell Biol. , vol.4
    • Yamada, K.M.1    Even-Ram, S.2
  • 43
    • 0347356291 scopus 로고    scopus 로고
    • The role of the IGF-I receptor in the regulation of matrix metalloproteinases, tumor invasion and metastasis
    • Zhang, D., A. A. Samani, and P. Brodt. 2003. The role of the IGF-I receptor in the regulation of matrix metalloproteinases, tumor invasion and metastasis. Horm. Metab. Res. 35:802-808.
    • (2003) Horm. Metab. Res. , vol.35 , pp. 802-808
    • Zhang, D.1    Samani, A.A.2    Brodt, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.