Clustering class I MHC modulates sensitivity of T cell recognition

Journal of Immunology

Volumn 176, Issue 11, 2006, Pages 6673-6680

  Fooksman, David R ^a   Grönvall, Gigi Kwik ^a,b   Tang, Qing ^a,c   Edidin, Michael ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^c Leica Microsystems Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; CHOLESTEROL; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; PEPTIDE;

ANIMAL CELL; ANTIGEN RECOGNITION; ARTICLE; CONTROLLED STUDY; DIMERIZATION; HUMAN; HUMAN CELL; IMMUNOSTIMULATION; MOLECULAR RECOGNITION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CROSS LINKING; SURFACE PROPERTY; T LYMPHOCYTE ACTIVATION;

EID: 33646885101     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.176.11.6673     Document Type: Article

References (30)

1. Sykulev, Y., Y. Vugmeyster, A. Brunmark, H. L. Ploegh, and H. N. Eisen. 1998. Peptide antagonism and T cell receptor interactions with peptide-MHC complexes. Immunity 9: 475-483.
2. Sykulev, Y., M. Joo, I. Vturina, T. J. Tsomides, and H. N. Eisen. 1996. Evidence that a single peptide-MHC complex on a target cell can elicit a cytolytic T cell response. Immunity 4: 565-571.
3. Wülfing, C., C. Sumen, M. D. Sjaastad, L. C. Wu, M. L. Dustin, and M. M. Davis. 2002. Costimulation and endogenous MHC ligands contribute to T cell recognition. Nat. Immunol. 3: 42-47.
4. Purbhoo, M. A., D. J. Irvine, J. B. Huppa, and M. M. Davis. 2004. T cell killing does not require the formation of a stable mature immunological synapse. Nat. Immunol. 5: 524-530.
5. Yachi, P. P., J. Ampudia, N. R. Gascoigne, and T. Zal. 2005. Nonstimulatory peptides contribute to antigen-induced CD8-T cell receptor interaction at the immunological synapse. Nat. Immunol. 6: 785-792.
6. Matko, J., Y. Bushkin, T. Wei, and M. Edidin. 1994. Clustering of class I HLA molecules on the surfaces of activated and transformed human cells. J. Immunol. 152: 3353-3360.
7. Vereb, G., J. Matko, G. Vamosi, S. M. Ibrahim, E. Magyar, S. Varga, J. Szollosi, A. Jenei, R. Gaspar, Jr., T. A. Waldmann, and S. Damjanovich. 2000. Cholesterol-dependent clustering of IL-2Rα and its colocalization with HLA and CD48 on T lymphoma cells suggest their functional association with lipid rafts. Proc. Natl. Acad. Sci. USA 97: 6013-6018.
8. 2-microglobulin: implications in activation of cytotoxic T lymphocytes. Int. Immunol. 15: 331-339.
9. Bodnár, A., A. Jenei, L. Bene, S. Damjanovich, and J. Matko. 1996. Modification of membrane cholesterol level affects expression and clustering of class I HLA molecules at the surface of JY human lymphoblasts. Immunol. Lett. 54: 221-226.
10. Kwik, J., S. Boyle, D. Fooksman, L. Margolis, M. P. Sheetz, and M. Edidin. 2003. Membrane cholesterol, lateral mobility, and the phosphatidylinositol 4,5-bisphosphate-dependent organization of cell actin. Proc. Natl. Acad. Sci. USA 100: 13964-13969.
11. Gheber, L. A., and M. Edidin. 1999. A model for membrane patchiness: lateral diffusion in the presence of barriers and vesicle traffic. Biophys. J. 77: 3163-3175.
12. Ritchie, K., R. Iino, T. Fujiwara, K. Murase, and A. Kusumi. 2003. The fence and picket structure of the plasma membrane of live cells as revealed by single molecule techniques (review). Mol. Membr. Biol. 20: 13-18.
13. Salter, R. D., and P. Cresswell. 1986. Impaired assembly and transport of HLA-A and -B antigens in a mutant TxB cell hybrid. EMBO J. 5: 943-949.
14. Chen, W., F. R. Carbone, and J. McCluskey. 1993. Electroporation and commercial liposomes efficiently deliver soluble protein into the MHC class I presentation pathway: priming in vitro and in vivo for class I-restricted recognition of soluble antigen. J. Immunol. Methods 160: 49-57.
15. Sykulev, Y., A. Brunmark, T. J. Tsomides, S. Kageyama, M. Jackson, P. A. Peterson, and H. N. Eisen. 1994. High-affinity reactions between antigen-specific T-cell receptors and peptides associated with allogeneic and syngeneic major histocompatibility complex class I proteins. Proc. Natl. Acad. Sci. USA 91: 11487-11491.
16. Spiliotis, E. T., T. Pentcheva, and M. Edidin. 2002. Probing for membrane domains in the endoplasmic reticulum: retention and degradation of unassembled MHC class I molecules. Mol. Biol. Cell 13: 1566-1581.
17. Zacharias, D. A., J. D. Violin, A. C. Newton, and R. Y. Tsien. 2002. Partitioning of lipid-modified monomeric GFPs into membrane microdomains of live cells. Science 296: 913-916.
18. Pentcheva, T., and M. Edidin. 2001. Clustering of peptide-loaded MHC class I molecules for endoplasmic reticulum export imaged by fluorescence resonance energy transfer. J. Immunol. 166: 6625-6632.
19. Taffs, R., and M. V. Sitkovsky. 1998. Granzyme enzyme exocytosis assay for cytotoxic T lymphocyte activation. In Current Protocols In Immunology. John Wiley & Sons, p. 3.16.1-3.16.3.
20. b haplotype reveal genetic control of isotype expression. J. Immunol. 126: 317-321.
21. b antigens determined with monoclonal antibodies and H-2 mutant mice. Proc. Natl. Acad. Sci. USA 79: 4737-4741.
22. Unruh, T. L., H. Li, C. M. Mutch, N. Shariat, L. Grigoriou, R. Sanyal, C. B. Brown, and J. P. Deans. 2005. Cholesterol depletion inhibits src family kinase-dependent calcium mobilization and apoptosis induced by rituximab crosslinking. Immunology 116: 223-232.
23. Clackson, T., W. Yang, L. W. Rozamus, M. Hatada, J. F. Amara, C. T. Rollins, L. F. Stevenson, S. R. Magari, S. A. Wood, N. L. Courage, et al. 1998. Rede-signing an FKBP-ligand interface to generate chemical dimerizers with novel specificity. Proc. Natl. Acad. Sci. USA 95: 10437-10442.
24. Stroynowski, I., J. Forman, R. S. Goodenow, S. G. Schiffer, M. McMillan, S. O. Sharrow, D. H. Sachs, and L. Hood. 1985. Expression and T cell recognition of hybrid antigens with amino-terminal domains encoded by Qa-2 region of major histocompatibility complex and carboxyl termini of transplantation antigens. J. Exp. Med. 161: 935-952.
25. Makkerh, J. P., C. Ceni, D. S. Auld, F. Vaillancourt, G. Dorval, and P. A. Barker. 2005. p75 neurotrophin receptor reduces ligand-induced Trk receptor ubiquitination and delays Trk receptor internalization and degradation. EMBO Rep. 6: 936-941.
26. Grasberger, B., A. P. Minton, C. DeLisi, and H. Metzger. 1986. Interaction between proteins localized in membranes. Proc. Natl. Acad. Sci. USA 83: 6258-6262.
27. Krogsgaard, M., Q. J. Li, C. Sumen, J. B. Huppa, M. Huse, and M. M. Davis. 2005. Agonist/endogenous peptide-MHC heterodimers drive T cell activation and sensitivity. Nature 434: 238-243.
28. Bacsó, Z., L. Bene, L. Damjanovich, and S. Damjanovich. 2002. IFN-γ rear-ranges membrane topography of MHC-I and ICAM-1 in colon carcinoma cells. Biochem. Biophys. Res. Commun. 290: 635-640.
29. Bene, L., A. Bodnár, S. Damjanovich, G. Vámosi, Z. Bacsó, J. Aradi, A. Berta, and J. Damjanovich. 2004. Membrane topography of HLA I, HLA II, and ICAM-1 is affected by IFN-γ in lipid rafts of uveal melanomas. Biochem. Biophys. Res. Commun. 322: 678-683.
30. Dudley, M. E., J. R. Wunderlich, T. E. Shelton, J. Even, and S. A. Rosenberg. 2003. Generation of tumor-infiltrating lymphocyte cultures for use in adoptive transfer therapy for melanoma patients. J. Immunother. 26: 332-342.