Evolutionary analysis of fructose 2,6-bisphosphate metabolism

IUBMB Life

Volumn 58, Issue 3, 2006, Pages 133-141

  Michels, Paul A M ^a,c   Rigden, Daniel J ^b  

^a DE DUVE INSTITUTE   (Belgium)

^b UNIVERSITY OF LIVERPOOL   (United Kingdom)

^c ICP TROP 7439 ^*  (Belgium)

Author keywords

6 phosphofructo 2 kinase; Domain architecture; Evolution; Fructose 2,6 bisphosphatase; Metabolic regulation; Phylogenetic distribution

Indexed keywords

6 PHOSPHOFRUCTO 2 KINASE; FRUCTOSE 2,6 BISPHOSPHATASE; FRUCTOSE 2,6 BISPHOSPHATE; ISOENZYME;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; BIOINFORMATICS; CARBOHYDRATE METABOLISM; CARBOXY TERMINAL SEQUENCE; CATALYSIS; DATA BASE; DEVELOPMENTAL STAGE; ENZYME ACTIVITY; ENZYME SPECIFICITY; ENZYME SYNTHESIS; EUKARYOTE; GENE DELETION; GENE DUPLICATION; GENOME; GLUCONEOGENESIS; GLYCOLYSIS; HYDROLYSIS; LIGAND BINDING; METABOLIC REGULATION; MOLECULAR EVOLUTION; NONHUMAN; PHYLOGENY; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; REVIEW;

ANIMALS; ENERGY METABOLISM; EVOLUTION, MOLECULAR; FRUCTOSEDIPHOSPHATES; HUMANS; PHOSPHOFRUCTOKINASE-2;

EUKARYOTA; PROTISTA;

EID: 33646871264     PISSN: 15216543     EISSN: 15216551     Source Type: Journal    
DOI: 10.1080/15216540600688280     Document Type: Review

References (37)

1. Van Schaftingen, E., Hue, L., and Hers, H. G. (1980) Fructose 2,6-bisphosphate, the probably structure of the glucose- and glucagon-sensitive stimulator of phosphofructokinase. Biochem. J. 192, 897-901.
2. Van Schaftingen, E., and Hers, H. G. (1981) Inhibition of fructose-1,6-bisphosphatase by fructose 2,6-biphosphate. Proc. Natl. Acad. Sci. USA 78, 2861-2863.
3. Okar, D. A., Manzano, A., Navarro-Sabate, A., Riera, L., Bartrons, R., and Lange, A. J. (2001) PFK-2/FBPase-2: maker and breaker of the essential biofactor fructose-2,6-bisphosphate. Trends Biochem. Sci. 26, 30-35.
4. Rider, M. H., Bertrand, L., Vertommen, D., Michels, P. A. M., Rousseau, G. G., and Hue, L. (2004) 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase: head-to-head with a bifunctional enzyme that controls glycolysis. Biochem. J. 381, 561-579.
5. Nielsen, T. H., Rung, J. H., and Villadsen, D. (2004) Fructose-2,6-bisphosphate: a traffic signal in plant metabolism. Trends Plant Sci. 9, 556-563.
6. Opperdoes, F. R., and Borst, P. (1977) Localization of nine glycolytic enzymes in a microbody-like organelle in Trypanosoma brucei: the glycosome. FEBS Lett. 80, 360-364.
7. Hannaert, V., Bringaud, F., Opperdoes, F. R., and Michels, P. A. M. (2003) Evolution of energy metabolism and its compartmentation in Kinetoplastida. Kinetoplastid Biol. Dis. 2, 11.http://www.kinetoplastids.com/ content/2/1/11
8. Van Schaftingen, E., Opperdoes, F. R., and Hers, G. (1985) Stimulation of Trypanosoma brucei pyruvate kinase by fructose 2,6-bisphosphate. Eur. J. Biochem. 153, 403-406.
9. Van Schaftingen, E., Opperdoes, F. R., and Hers, H. G. (1987) Effects of various metabolic conditions and of the trivalent arsenical melarsen oxide on the intracellular levels of fructose 2,6-bisphosphate and of glycolytic intermediates in Trypanosoma brucei. Eur. J. Biochem. 166, 653-661.
10. Pilkis, S. J., Chrisman, T., Burgress, B., McGrane, M., Colosia, A., Pilkis, J., Claus, T. H., and El-Maghrabi, M. R. (1983) Rat hepatic 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase: a unique bifunctional enzyme. Adv. Enzyme Regul. 21, 147-173.
11. Hasemann, C. A., Istvan, E. S., Uyeda, K., and Deisenhofer, J. (1996) The crystal structure of the bifunctional enzyme 6-phosphofructo-2-kinase/fructose- 2,6-bisphosphatase reveals distinct domain homologies. Structure 4, 1017-1029.
12. Bertrand, L., Vertommen, D., Depiereux, E., Hue, L., Rider, M. H., and Feytmans, E. (1997) Modelling the 2-kinase domain of 6-phosphofructo-2-kinase/ fructose-2,6-bisphosphatase on adenylate kinase. Biochem. J. 321, 615-621.
13. Bazan, J. F., Fletterick, R. J., and Pilkis, S. J. (1989) Evolution of a bifunctional enzyme: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase. Proc. Natl. Acad. Sci. USA 86, 9642-9646.
14. Kretschmer, M., and Fraenkel, D. G. (1991) Yeast 6-phosphofructo-2- kinase: sequence and mutant. Biochemistry 30, 10663-10672.
15. Paravicini, G., and Kretschmer, M. (1992) The yeast FBP26 gene codes for a fructose-2,6-bisphosphatase. Biochemistry 31, 7126-7133.
16. Boles, E., Gohlmann, H. W., and Zimmermann, F. K. (1996) Cloning of a second gene encoding 6-phosphofructo-2-kinase in yeast, and characterization of mutant strains without fructose 2,6-bisphosphate. Mol. Microbiol. 20, 65-76.
17. Chevalier, N., Bertrand, L., Rider, M. H., Opperdoes, F. R., Rigden, D. J., and Michels, P. A. M. (2005) 6-Phosphofructo-2-kinase and fructose-2,6-bisphosphatase in Trypanosomatidae. Molecular characterization, database searches, modelling studies and evolutionary analysis. FEBS J. 272, 3542-3560.
18. Van Schaftingen, E., Mertens, E., and Opperdoes, F. R. (1990) Fructose 2,6-bisphosphate in primitive systems. In Fructose 2,6-bisphosphate (Pilkis S. J., ed.). pp. 229-244, CRC Press, Boca Raton.
19. Marcus, F., Edelstein, I., and Rittenhouse, J. (1984) Inhibition of Escherichia coli fructose-1,6-bisphosphatase by fructose 2,6-bisphosphate. Biochem. Biophys. Res. Commun. 119, 1103-1108.
20. Rittmann, D., Schaffer, S., Wendisch, V. F., and Sahm, H. (2003) Fructose-1,6-bisphosphatase from Corynebacterium glutamicum: expression and deletion of the fbp gene and biochemical characterization of the enzyme. Arch. Microbiol. 180, 285-292.
21. Mizuguchi, H., Cook, P. F., Tai, C. H., Hasemann, C. A., and Uyeda, K. (1999) Reaction mechanism of fructose-2,6-bisphosphatase. A mutation of nucleophilic catalyst, histidine 256, induces an alteration in the reaction pathway. J. Biol. Chem. 274, 2166-2175.
22. Bertrand, L., Deprez, J., Vertommen, D., Di Pietro, A., Hue, L., and Rider, M. H. (1997) Site-directed mutagenesis of Lys-174, Asp-179 and Asp-191 in the 2-kinase domain of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase. Biochem. J. 321, 623-627.
23. Kim, S. G., Manes, N. P., El-Maghrabi, M. R., and Lee, Y. H. (2006) Crystal structure of the hypoxia-inducible form of 6-phosphofructo-2-kinase/ fructose-2,6-bisphosphatase (PFKFB3): a possible new target for cancer therapy. J. Biol. Chem. 281, 2939-2944.
24. Koonin, E. V., Makarova, K. S., and Aravind, L. (2001) Horizontal gene transfer in prokaryotes: quantification and classification. Annu. Rev. Microbiol. 55, 709-742.
25. Calteau, A., Gouy, M., and Perriere, G. (2005) Horizontal transfer of two operons coding for hydrogenases between bacteria and archaea. J. Mol. Evol. 60, 557-565.
26. Poorman, R. A., Randolph, A., Kemp, R. G., and Heinrikson, R. L. (1984) Evolution of phosphofructokinase - gene duplication and creation of new effector sites. Nature 309, 467-469.
27. Fothergill-Gilmore, L. A., and Michels, P. A. M. (1993) Evolution of glycolysis. Prog. Biophys. Mol. Biol. 59, 105-235.
28. Li, Y., Rivera, D., Ru, W., Gunasekera, D., and Kemp, R. G. (1999) Identification of allosteric sites in rabbit phosphofructo-1-kinase. Biochemistry 38, 16407-16412.
29. Meyer, A., and Schartl, M. (1999) Gene and genome duplications in vertebrates: the one-to-four (-to-eight in fish) rule and the evolution of novel gene functions. Curr. Opin. Cell Biol. 11, 699-704.
30. Sedgwick, S. G., and Smerdon, S. J. (1999) The ankyrin repeat: a diversity of interactions on a common structural framework. Trends Biochem. Sci. 24, 311-316.
31. Lee, Y. H., Li, Y., Uyeda, K., and Hasemann, C. A. (2003) Tissue-specific structure/function differentiation of the liver isoform of 6-phosphofructo-2- kinase/fructose-2,6-bisphosphatase. J. Biol. Chem. 278, 523-530.
32. Rigden, D. J., Bagyan, I., Lamani, E., Setlow, P., and Jedrzejas, M. J. (2001) A cofactor-dependent phosphoglycerate mutase homolog from Bacillus stearothermophilus is actually a broad specificity phosphatase. Protein Sci. 10, 1835-1846.
33. Tauler, A., Lange, A. J., El-Maghrabi, M. R., and Pilkis, S. J. (1989) Expression of rat liver 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase and its kinase domain in Escherichia coli. Proc. Natl. Acad. Sci. USA 86, 7316-7320.
34. Liang, J. Y., Huang, S., Zhang, Y., Ke, H., and Lipscomb, W. N. (1992) Crystal structure of the neutral form of fructose 1,6-bisphosphatase complexed with regulatory inhibitor fructose 2,6-bisphosphate at 2.6-Å resolution. Proc. Natl. Acad. Sci. USA 89, 2404-2408.
35. 2+ at 2.0-Å resolution: aspects of synergism between inhibitors. Proc. Natl. Acad. Sci. USA 91, 12482-12486.
36. Kraft, L., Sprenger, G. A., and Lindqvist, Y. (2002) Conformational changes during the catalytic cycle of gluconate kinase as revealed by X-ray crystallography. J. Mol. Biol. 318, 1057-1069.
37. Rigden, D. J., Littlejohn, J. E., Henderson, K., and Jedrzejas, M. J. (2003) Structures of phosphate and trivanadate complexes of Bacillus stearothermophilus phosphatase PhoE: structural and functional analysis in the cofactor-dependent phosphoglycerate mutase superfamily. J. Mol. Biol. 325, 411-420.