Reaction mechanism of fructose-2,6-bisphosphatase: A mutation of nucleophilic catalyst, histidine 256, induces an alteration in the reaction pathway

Journal of Biological Chemistry

Volumn 274, Issue 4, 1999, Pages 2166-2175

  Mizuguchi, Hiroyuki ^a,b   Cook, Paul F ^c   Tai, Chia Hui ^c   Hasemann, Charles A ^b   Uyeda, Kosaku ^a,b  

^a VA NORTH TEXAS HEALTH CARE SYSTEM   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c UNIVERSITY OF OKLAHOMA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FRUCTOSE 2,6 BISPHOSPHATASE;

AMINO ACID ANALYSIS; ARTICLE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME MECHANISM; ENZYME PHOSPHORYLATION; HYDROLYSIS; PRIORITY JOURNAL;

ANIMALS; BINDING SITES; CATALYTIC DOMAIN; HISTIDINE; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; MUTAGENESIS, SITE-DIRECTED; PHOSPHOFRUCTOKINASE-2; PHOSPHORIC MONOESTER HYDROLASES; PHOSPHORYLATION; PROTEIN CONFORMATION; RATS;

FELIS CATUS;

EID: 0033593224     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.4.2166     Document Type: Article

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