Selective hydroxylation of highly branched fatty acids and their derivatives by CYP102A1 from Bacillus megaterium

ChemBioChem

Volumn 7, Issue 5, 2006, Pages 789-794

  Budde, Michael ^a   Morr, Michael ^b   Schmid, Rolf D ^a   Urlacher, Vlada B ^a  

^a UNIVERSITY OF STUTTGART   (Germany)

^b HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

Author keywords

Binding spectra; Cytochromes; Fatty acids; Monooxygenases; P450 BM 3; Polyketides

Indexed keywords

ALKANE; ALKANOIC ACID; CYTOCHROME P450; CYTOCHROME P450 102A2; CYTOCHROME P450 102A3; CYTOCHROME P450 BM3; FATTY ACID DERIVATIVE; UNCLASSIFIED DRUG; UNSPECIFIC MONOOXYGENASE;

ARTICLE; BACILLUS MEGATERIUM; ENZYME ANALYSIS; ENZYME BINDING; HYDROXYLATION; PRIORITY JOURNAL; WILD TYPE;

BACILLUS MEGATERIUM; BACTERIAL PROTEINS; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; CYTOCHROME P-450 ENZYME SYSTEM; FATTY ACIDS; HYDROXYLATION; MIXED FUNCTION OXYGENASES; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MUTATION;

ANSER ANSER; BACILLUS MEGATERIUM; BACILLUS SUBTILIS; CAIRINA MOSCHATA;

EID: 33646806119     PISSN: 14394227     EISSN: 14397633     Source Type: Journal    
DOI: 10.1002/cbic.200500444     Document Type: Article

References (24)

1. D. Werck-Reichhart, R. Feyereisen, Genome Biol. 2000, 1, reviews 3003.1-3003.9.
2. L. L. Wong, Curr. Opin. Chem. Biol. 1998, 2, 263.
3. K. J. McLean, M. Sabri, K. R. Marshall, R. J. Lawson, D. G. Lewis, D. Clift, P. R. Balding, A. J. Dunford, A. J. Warman, J. P. McVey, A. M. Quinn, M. J. Sutcliffe, N. S. Scrutton, A. W. Munro, Biochem. Soc Trans. 2005, 33, 796.
4. C. N. A. Palmer, E. Axen, V. Hughes, C. R. Wolf, J. Biol. Chem. 1998, 273, 18109.
5. M. C. Gustafsson, C. N. Palmer, C. R. Wolf, C. von Wachenfeldt, Arch. Microbiol. 2001, 176, 459.
6. M. C. Gustafsson, O. Roitel, K. R. Marshall, M. A. Noble, S. K. Chapman, A. Pessegueiro, A. J. Fulco, M. R. Cheesman, C. von Wachenfeldt, A. W. Munro, Biochemistry 2004, 43, 5474.
7. T. Kaneda, Microbiol. Rev. 1991, 55, 288.
8. M. Morr, V. Wray, J. Fortkamp, R. D. Schmid, Liebigs Ann. Chem. 1992, 433.
9. Y. J. Yoon, B. J. Beck, B. S. Kim, H. Y. Kang, K. A. Reynolds, D. H. Sherman, Chem. Biol. 2002, 9, 203.
10. Y. Q. Xue, D. Wilson, L. S. Zhao, H. W. Liu, D. H. Sherman, Chem. Biol. 1998, 5, 661.
11. B. G. Vong, S. Abraham, A. X. Xiang, E. A. Theodorakis, Org. Lett. 2003, 5, 1617.
12. D. Appel, S. Lutz-Wahl, P. Fischer, U. Schwaneberg, R. D. Schmid, J. Biotechnol. 2001, 88, 167.
13. U. Schwaneberg, A. Sprauer, C. Schmidt-Dannert, R. D. Schmid, J. Chromatogr. A 1999, 848, 149.
14. G. Truan, M. R. Komandla, J. R. Falck, J. A. Peterson, Arch. Biochem. Biophys. 1999, 366, 192.
15. A. Glieder, E. T. Farinas, F. H. Arnold, Nat. Biotechnol. 2002, 20, 1135.
16. Y. Miura, A. J. Fulco, Biochim. Biophys. Acta 1975, 388, 305.
17. S. A. Maves, H. Yeom, M. A. McLean, S. G. Sugar, FEBS Lett. 1997, 414, 213.
18. J. B. Schenkman, S. G. Sugar, D. L. Cinti, Pharmacol. Ther. 1981, 12, 43.
19. Q.-S. Li, U. Schwaneberg, M. Fischer, J. Schmitt, J. Pleiss, S. Lutz-Wahl, R. D. Schmid, Biochim. Biophys. Acta 2001, 1545, 114.
20. H. Li, T. L. Poulos, Nat. Struct, Biol. 1997, 4, 140.
21. M. Budde, S. C. Maurer, R. D. Schmid, V. B. Urlacher, Appl. Microbiol. Biotechnol. 2004, 66, 180.
22. Q.-S. Li, U. Schwaneberg, P. Fischer, R. D. Schmid, Chem. Eur. J. 2000, 6, 1481.
23. T. Omura, R. J. Sato, J. Biol. Chem. 1964, 239, 2370.
24. M. A. Noble, C. S. Miles, S. K. Chapman, D. A. Lysek, A. C. MacKay, G. A. Reid, R. P. Hanzlik, A. W. Munro, Biochem. J. 1999, 339, 371.