Neisseria meningitidis infection of human endothelial cells interferes with leukocyte transmigration by preventing the formation of endothelial docking structures

Journal of Cell Biology

Volumn 173, Issue 4, 2006, Pages 627-637

  Doulet, Nicolas ^a,b,c,d   Donnadieu, Emmanuel ^a,b,c,d   Laran Chich, Marie Pierre ^a,b,c,d   Niedergang, Florence ^a,b,c,d   Nassif, Xavier ^b   Couraud, Pierre Olivier ^a,b,c,d   Bourdoulous, Sandrine ^a,b,c,d  

^a INSTITUT COCHIN   (France)

^b INSERM   (France)

^c CNRS   (France)

^d UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; CELL ADHESION MOLECULE; DOCKING PROTEIN; EZRIN; LIPID BINDING PROTEIN; MOESIN; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE;

ACTIN POLYMERIZATION; AMINO TERMINAL SEQUENCE; ARTICLE; BACTERIUM ADHERENCE; BACTERIUM COLONY; CELL ADHESION; CELL INTERACTION; CELL STRUCTURE; CELL SURFACE; CONTROLLED STUDY; ENDOTHELIUM CELL; GROWTH INHIBITION; HUMAN; HUMAN CELL; LEUKOCYTE ADHERENCE; LEUKOCYTE MIGRATION; LEUKOCYTE MOTILITY; MONOLAYER CULTURE; NEISSERIA MENINGITIDIS; NEISSERIACEAE INFECTION; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION;

CELL ADHESION; CELL ADHESION MOLECULES; CELL COMMUNICATION; CELL MEMBRANE; CELLS, CULTURED; CHEMOTAXIS, LEUKOCYTE; CYTOSKELETAL PROTEINS; ENDOTHELIAL CELLS; HUMANS; IMMUNE TOLERANCE; INTERCELLULAR JUNCTIONS; LEUKOCYTES; MENINGITIS, MENINGOCOCCAL; MICROFILAMENT PROTEINS; NEISSERIA MENINGITIDIS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY;

BACTERIA (MICROORGANISMS); NEISSERIA MENINGITIDIS;

EID: 33646806054     PISSN: 00219525     EISSN: 00219525     Source Type: Journal    
DOI: 10.1083/jcb.200507128     Document Type: Article

References (30)

1. Barreiro, O., M. Yanez-Mo, J.M. Serrador, M.C. Montoya, M. Vicente-Manzanares, R. Tejedor, H. Furthmayr, and F. Sanchez-Madrid. 2002. Dynamic interaction of VCAM-1 and ICAM-1 with moesin and ezrin in a novel endothelial docking structure for adherent leukocytes. J. Cell Biol. 157:1233-1245.
2. Barreiro, O., M. Yanez-Mo, M. Sala-Valdes, M.D. Gutierrez-Lopez, S. Ovalle, A. Higginbottom, P.N. Monk, C. Cabanas, and F. Sanchez-Madrid. 2005. Endothelial tetraspanin microdomains regulate leukocyte firm adhesion during extravasation. Blood. 105:2852-2861.
3. 2-terminal domain of ezrin correlates with its altered cellular distribution. J. Cell Biol. 151:1067-1080.
4. Bazzoni, G. 2003. The JAM family of junctional adhesion molecules. Curr. Opin. Cell Biol. 15:525-530.
5. Beekhuizen, H., J.S. van de Gevel, B. Olsson, I.J. van Benten, and R. van Furth. 1997. Infection of human vascular endothelial cells with Staphylococcus aureus induces hyperadhesiveness for human monocytes and granulocytes. J. Immunol. 158:774-782.
6. Bretscher, A., K. Edwards, and R.G. Fehon. 2002. ERM proteins and merlin: integrators at the cell cortex. Nat. Rev. Mol. Cell Biol. 3:586-599.
7. Carman, C.V., and T.A. Springer. 2004. A transmigratory cup in leukocyte diapedesis both through individual vascular endothelial cells and between them. J. Cell Biol. 167:377-388.
8. Carman, C.V., C.D. Jun, A. Salas, and T.A. Springer. 2003. Endothelial cells proactively form microvilli-like membrane projections upon intercellular adhesion molecule 1 engagement of leukocyte LFA-1. J. Immunol. 171:6135-6144.
9. Cinamon, G., V. Shinder, R. Shamri, and R. Alon. 2004. Chemoattractant signals and beta 2 integrin occupancy at apical endothelial contacts combine with shear stress signals to promote transendothelial neutrophil migration. J. Immunol. 173:7282-7291.
10. Cook-Mills, J.M., and T.L. Deem. 2005. Active participation of endothelial cells in inflammation. J. Leukoc. Biol. 77:487-495.
11. Cook-Mills, J.M., J.D. Johnson, T.L. Deem, A. Ochi, L. Wang, and Y. Zheng. 2004. Calcium mobilization and Rac1 activation are required for VCAM-1 (vascular cell adhesion molecule-1) stimulation of NADPH oxidase activity. Biochem. J. 378:539-547.
12. Crepaldi, T., A. Gautreau, P.M. Comoglio, D. Louvard, and M. Arpin. 1997. Ezrin is an effector of hepatocyte growth factor-mediated migration and morphogenesis in epithelial cells. J. Cell Biol. 138:423-434.
13. Edwards, R.J., G.W. Taylor, M. Ferguson, S. Murray, N. Rendell, A. Wrigley, Z. Bai, J. Boyle, S.J. Finney, A. Jones, et al. 2005. Specific C-terminal cleavage and inactivation of interleukin-8 by invasive disease isolates of Streptococcus pyogenes. J. Infect. Dis. 192:783-790.
14. Etienne-Manneville, S., J.B. Manneville, P. Adamson, B. Wilbourn, J. Greenwood, and P.O. Couraud. 2000. ICAM-1-coupled cytoskeletal rearrangements and transendothelial lymphocyte migration involve intracellular calcium signaling in brain endothelial cell lines. J. Immunol. 165:3375-3383.
15. Eugene, E., I. Hoffmann, C. Pujol, P.O. Couraud, S. Bourdoulous, and X. Nassif. 2002. Microvilli-like structures are associated with the internalization of virulent capsulated Neisseria meningitidis into vascular endothelial cells. J. Cell Sci. 115:1231-1241.
16. Fievet, B.T., A. Gautreau, C. Roy, L. Del Maestro, P. Mangeat, D. Louvard, and M. Arpin. 2004. Phosphoinositide binding and phosphorylation act sequentially in the activation mechanism of ezrin. J. Cell Biol. 164:653-659.
17. Gautreau, A., D. Louvard, and M. Arpin. 2002. ERM proteins and NF2 tumor suppressor: the Yin and Yang of cortical actin organization and cell growth signaling. Curr. Opin. Cell Biol. 14:104-109.
18. Hoffmann, I., E. Eugene, X. Nassif, P.O. Couraud, and S. Bourdoulous. 2001. Activation of ErbB2 receptor tyrosine kinase supports invasion of endothelial cells by Neisseria meningitidis. J. Cell Biol. 155:133-143.
19. Hornef, M.W., M.J. Wick, M. Rhen, and S. Normark. 2002. Bacterial strategies for overcoming host innate and adaptive immune responses. Nat. Immunol. 3:1033-1040.
20. Krull, M., R. Nost, S. Hippenstiel, E. Domann, T. Chakraborty, and N. Suttorp. 1997. Listeria monocytogenes potently induces up-regulation of endothelial adhesion molecules and neutrophil adhesion to cultured human endothelial cells. J. Immunol. 159:1970-1976.
21. Lambotin, M., I. Hoffmann, M. Laran-chich, X. Nassif, P.O. Couraud, and S. Bourdoulous. 2005. Invasion of endothelial cells by Neisseria meningitidis requires cortactin recruitment by a PI3-kinase/Rac1 signalling pathway triggered by the lipo-oligosaccharide. J. Cell Sci. 118:3805-3816.
22. Millan, J., and A.J. Ridley. 2005. Rho GTPases and leucocyte-induced endothelial remodelling. Biochem. J. 385:329-337.
23. Nassif, X., S. Bourdoulous, E. Eugene, and P.O. Couraud. 2002. How do extracellular pathogens cross the blood-brain barrier? Trends Microbiol. 10:227-232.
24. Rosenberger, C.M., and B.B. Finlay. 2003. Phagocyte sabotage: disruption of macrophage signalling by bacterial pathogens. Nat. Rev. Mol. Cell Biol. 4:385-396.
25. Schenkel, A.R., Z. Mamdouh, and W.A. Muller. 2004. Locomotion of monocytes on endothelium is a critical step during extravasation. Nat. Immunol. 5:393-400.
26. Shaw, S.K., S. Ma, M.B. Kim, R.M. Rao, C.U. Hartman, R.M. Froio, L. Yang, T. Jones, Y. Liu, A. Nusrat, et al. 2004. Coordinated redistribution of leukocyte LFA-1 and endothelial cell ICAM-1 accompany neutrophil transmigration. J. Exp. Med. 200:1571-1580.
27. Trautmann, A., and S. Valitutti. 2003. The diversity of immunological synapses. Curr. Opin. Immunol. 15:249-254.
28. van Deuren, M., P. Brandtzaeg, and J.W. van der Meer. 2000. Update on meningococcal disease with emphasis on pathogenesis and clinical management. Clin. Microbiol. Rev. 13:144-166 (table of contents.).
29. Wojciak-Stothard, B., L. Williams, and A.J. Ridley. 1999. Monocyte adhesion and spreading on human endothelial cells is dependent on Rho-regulated receptor clustering. J. Cell Biol. 145:1293-1307.
30. Yang, L., R.M. Froio, T.E. Sciuto, A.M. Dvorak, R. Alon, and F.W. Luscinskas. 2005. ICAM-1 regulates neutrophil adhesion and transcellular migration of TNF-alpha-activated vascular endothelium under flow. Blood. 106:584-592.