Neurocognitive models of schizophrenia: The prefrontal cortex role;Modelos neurocognitivos en la esquizofrenia: Rol del córtex prefrontal

Revista Chilena de Neuro-Psiquiatria

Volumn 44, Issue 1, 2006, Pages 39-47

  Orellana V , Gricel ^a,b   Slachevsky Ch , Andrea ^b,c   Silva, Jaime R ^d  

^a UNIVERSITY OF CHILE   (Chile)

^b UNIVERSITY OF CHILE   (Chile)

^c HOSPITAL DEL SALVADOR   (Chile)

^d UNIVERSIDAD MAYOR   (Chile)

Author keywords

Neurocognitive approach; Prefrontal c rtex; Schizophrenia

Indexed keywords

ARTICLE; COGNITION; CONTROLLED STUDY; HUMAN; MENTAL DISEASE; PREFRONTAL CORTEX; SCHIZOPHRENIA; SYMPTOMATOLOGY;

EID: 33646789099     PISSN: 00347388     EISSN: 07179227     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Frith CD. The cognitive neuropsychology of schizophrenia. Hove: Lawrence Erlbaum Ltd., 1992.
2. Goldberg TE, Gold JM. Neurocognitive functioning in patients with schizophrenia en FE Bloom, DJ Kupfer (Editores). Neuropsychopharmacology: the fourth generation of progress. Eds. Raven, New York 2000; 658-671.
3. Andreasen NC. Symptoms, signs, and diagnosis of schizophrenia. Lancet 1995; 346: 477-481.
4. Lezak MD. Neuropsychological Assessment. New York -Oxford, Oxford University Press, 1995.
5. Slachevsky A, Pérez C, Silva J, Orellana G, Prenafreta M, Alegria P, et al. Córtex prefrontal y trastornos del comportamiento: Modelos explicativos y métodos de evaluación. Rev Chilena de Neuro-psiquiatría 2005; 43: 109-121.
6. Pantelis C, Stephen JW, Maruff P. Schizophrenia. Harrison JE y Owen AM. Martín Dunitz. (Editores) Cognitive déficit in brain disorders. Raven Press 2002; 217-248.
7. Andreasen NC, O'Leary DS, Flaum M, Nopoulos P, Watkins GL, Boles Ponto LL, et al. Hypofrontality in schizophrenia: distributed dysfunctional circuits in neurolepticnaive patients. Lancet 1997; 349: 1730-1734.
8. Weinberger DR, Berman KF. Prefrontal function in schizophrenia: confounds and controversies. Editado por Roberts, Robbins y Weiskrantz. En: The Prefrontal Córtex, executive and cognitive functions. Oxford University Press. 1998.
9. Callicott JH, Mattay VS, Verchinski BA, Marenco S, Egan MF, Weinberger DR. Complexity of prefrontal cortical dysfunction in schizophrenia: more than up or down. Am J Psychiatry 2003; 160: 2209-2215.
10. Braver TS, Barch TS, Cohen JD. Cognition and control in schizophrenia: a computational model of dopamine and prefrontal function. Biol Psychiatry 1999; 46: 312-328.
11. Ritter LM, Meador-Woodruff JH, Dalack GW. Neurocognitive measures of prefrontal cortical dysfunction in schizophrenia. Schizophr Res 2004; 68: 65-73.
12. Slachevsky A, Alegría P. Síndrome parietal y occipital. En Nogales-Gaete J, Donoso A, Verdugo R (Editores). Tratado de Neurología Clínica. Santiago, Ediciones Universitaria y SONEPSYN. 2005. pp
13. Andreasen NC. Linking mind and brain in the study of mental illnesses: a Project for a scientific psychopathology. Science 1997; 275: 1586-1593.
14. Nopoulos PC, Ceilley JW, Gailis EA, Andreasen NC. An MRI study of cerebellar vermis morphology in patients with schizophrenia: evidence in support of the cognitive dysmetria concept. Biol Psychiatry 1999; 46: 703-711.
15. Frith CD. The cognitive abnormalities underlying the symptomatology and the disability of patients with schizophrenia. Int Clin Psychopharmacol 1995; 10 Suppl 3: 87-98.
16. Frith CD, Friston KJ, Herold S, Silbersweig D, Fletcher P, Cahill C, et al. Regional brain activity in chronic schizophrenic patients during the performance of a verbal fluency task. Br J Psychiatry 1995; 167: 343-349.
17. Frith CD, Blakemore S, Wolpert DM. Explaining the symptoms of schizophrenia: abnormalities in the awareness of action. Brain Res Brain Res Rev 2000; 31: 357-63.
18. Frith C. The role of the prefrontal córtex in self-consciousness: the case of auditory hallucinations. Philos Trans R Soc Lond B Biol Sci 1996; 351: 1505-1512.
19. Andreasen NC. Schizophrenia: the fundamental questions. Brain Res Rev 2000; 31: 106-112.
20. Pantelis C, Maruff P. The cognitive neuropsychiatric approach to investigating the neurobiology of schizophrenia and other disorders. J Psychosom Res 2002; 53: 655-4.