The binding of actin to p38 MAPK and inhibiting its kinase activity in vitro

Science in China, Series C: Life Sciences

Volumn 46, Issue 1, 2003, Pages 87-94

  Yang, Kun ^a   Jiang, Yong ^b   Han, Jiahuai ^c   Gu, Jun ^d  

^a SUN YAT SEN UNIVERSITY   (China)

^b SOUTHERN MEDICAL UNIVERSITY   (China)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

^d PEKING UNIVERSITY   (China)

Author keywords

Actin; Mitogen activated protein kinase (MAP kinase, MAPK); p38 MAPK; Protein protein interaction; Signal transduction

Indexed keywords

ACTIN; MITOGEN-ACTIVATED PROTEIN KINASE (MAP KINASE, MAPK); P38 MAPK; PROTEIN-PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

CELLS; MASS SPECTROMETERS; PATHOLOGY; PHYSIOLOGY; ULTRAVIOLET RADIATION;

ENZYMES;

ACTIN; ACTIVATING TRANSCRIPTION FACTOR 2; ATF2 PROTEIN, MOUSE; MITOGEN ACTIVATED PROTEIN KINASE P38; RECOMBINANT PROTEIN;

ANIMAL; ARTICLE; CELL LINE; DRUG ANTAGONISM; FEEDBACK SYSTEM; IN VITRO STUDY; METABOLISM; MOUSE; PHOSPHORYLATION; PROTEIN BINDING; SIGNAL TRANSDUCTION;

ACTINS; ACTIVATING TRANSCRIPTION FACTOR 2; ANIMALS; CELL LINE; FEEDBACK, PHYSIOLOGICAL; MAP KINASE SIGNALING SYSTEM; MICE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTEIN BINDING; RECOMBINANT PROTEINS;

EID: 33646781558     PISSN: 10069305     EISSN: None     Source Type: Journal    
DOI: 10.1360/03yc9010     Document Type: Article

References (34)

1. Chang, L., Karin, M., Mammalian MAP kinase signalling cascades, Nature, 2001, 410(6824): 37-40.
2. Ono, K., Han, J., The p38 signal transduction pathway: activation and function, Cell Signal, 2000, 12(1): 1-13.
3. New, L., Han, J., The p38 MAP kinase pathway and its biological function, Trends Cardiovasc. Med., 1998, 8(5): 220-228.
4. Lee, J. C., Kumar, S., Griswold, D. E. et al., Inhibition of p38 MAP kinase as a therapeutic strategy, Immunopharmacology, 2000, 47(2-3): 185-201.
5. Lee, J. C., Kassis, S., Kumar, S. et al., p38 mitogen-activated protein kinase inhibitors-mechanisms and therapeutic potentials, Pharmacol. Ther., 1999, 82(2-3): 389-397.
6. Badger, A. M., Griswold, D. E., Kapadia, R. et al., Disease-modifying activity of SB 242235, a selective inhibitor of p38 mitogen-activated protein kinase, in rat adjuvant-induced arthritis, Arthritis Rheum, 2000, 43(1): 175-183.
7. Wadsworth, S. A., Cavender, D. E., Beers, S. A. et al., RWJ 67657, a potent, orally active inhibitor of p38 mitogen-activated protein kinase, J. Pharmacol. Exp. Ther., 1999, 291(2): 680-687.
8. Zhang, Z., Xin, S. M., Wu, G. X. et al., Endogenous delta-opioid and ORL1 receptors couple to phosphorylation and activation of p38 MAPK in NG108-15 cells and this is regulated by protein kinase A and protein kinase C, J. Neurochem., 999, 73(4): 1502-1509.
9. Jun, C. D., Oh, C. D., Kwak, H. J. et al., Overexpression of protein kinase C isoforms protects RAW264.7 macrophages from nitric oxide-induced apoptosis: involvement of c-Jun N-terminal kinase/stress-activated protein kinase, p38 kinase, and CPP-32 protease pathways, J. Immunol., 1999, 162(6): 3395-3401.
10. Zhang, Y., Neo, S. Y., Han, J. et al., RGS16 attenuates galphaq-dependent p38 mitogen-activated protein kinase activation by platelet-activating factor, J. Biol. Chem., 1999, 274(5): 2851-2857.
11. Zimmermann, B., Herberg, F. W., Interactions of 6×His-tagged protein kinase A catalytic subunit examined using Ni-NTA magnetic agarose beads, QIAGEN News, 1998, 4: 9-10.
12. Landry, J., Huot, J., Modulation of actin dynamics during stress and physiological stimulation by a signaling pathway involving p38 MAP kinase and heat-shock protein 27, Biochem. Cell Biol., 1995, 73(9-10): 703-707.
13. Jiang, Y., Chen, C., Li, Z. et al., Characterization of the structure and function of a new mitogen-activated protein kinase (p38beta), J. Biol. Chem., 1996, 271(30): 17920-17926.
14. Han, J., Lee, J. D., Jiang, Y. et al., Characterization of the structure and function of a novel MAP kinase kinase (MKK6), J. Biol. Chem., 1996, 271(6): 2886-2891.
15. Guan, K. L., Dixon, J. E., Eukaryotic proteins expressed in Escherichia coli: an improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase, Anal. Biochem., 1991, 192(2): 262-267.
16. Virca, G. D., Kim, S. Y., Glaser, K. B. et al., Lipopolysaccharide induces hyporesponsiveness to its own action in RAW 264.7 cells, J. Biol. Chem., 1989, 264(36): 21951-21956.
17. Jiang, Y., Gram, H., Zhao, M. et al., Characterization of the structure and function of the fourth member of p38 group mitogen-activated protein kinases, p38delta, J. Biol. Chem., 1997, 272(48): 30122-30128.
18. Pappin, D. J., Peptide mass fingerprinting using MALDI-TOF mass spectrometry, Methods Mol. Biol., 1997, 64: 165-173.
19. Zhang, W., Chait, B. T., ProFound: An expert system for protein identification using mass spectrometric peptide mapping information, Analytical Chemistry, 2000, 72(11): 2482-2489.
20. Phizicky, E. M., Fields, S., Protein-protein interactions: methods for detection and analysis, Microbiol. Rev., 1995, 59(1): 94-123.
21. Machesky, L. M., Insall, R. H., Signaling to actin dynamics, J. Cell Biol., 1999, 146(2): 267-272.
22. Zigmond, S. H., Signal transduction and actin filament organization, Curr. Opin. Cell Biol., 1996, 8(1): 66-73.
23. Tsakiridis, T., Wang, Q., Taha, C. et al., Involvement of the actin network in insulin signalling, Soc. Gen. Physiol. Ser., 1997, 52: 257-271.
24. Peppelenbosch, M., Boone, E., Jones, G. E. et al., Multiple signal transduction pathways regulate TNF-induced actin reorganization in macrophages: inhibition of Cdc42-mediated filopodium formation by TNF, J. Immunol., 1999, 162(2): 837 -845.
25. Zhu, P., Xiong, W., Rodgers, G et al., Regulation of interleukin 1 signalling through integrin binding and actin reorganization: disparate effects on NF-kappaB and stress kinase pathways, Biochem. J., 1998, 330(Pt 2): 975-981.
26. Sotiropoulos, A., Gineitis, D., Copeland, J. et al., Signal-regulated activation of serum response factor is mediated by changes in actin dynamics, Cell, 1999, 98(2): 159-169.
27. Goebel, J., Franks, A., Robey, F. et al., Attenuation of IL-2 receptor signaling by CD4-ligation requires polymerized cytoskeletal actin but not P56LCK, Transplant Proc., 1999, 31(1-2): 822-824.
28. Holsinger, L. J., Graef, I. A., Swat, W. et al., Defects in actin-cap formation in Vav-deficient mice implicate an actin requirement for lymphocyte signal transduction, Curr. Biol., 1998, 8(10): 563-572.
29. Edwards, D. C., Sanders, L. C., Bokoch, G. M. et al., Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics, Nat. Cell Biol., 1999, 1(5): 253-259.
30. Chakravortty, D., Nanda-Kumar, K. S., Bacterial lipopolysaccharide induces cytoskeletal rearrangement in small intestinal lamina propria fibroblasts: actin assembly is essential for lipopolysaccharide signaling, Biochim. Biophys. Acta, 2000, 1500(1): 125-136.
31. Maekawa, T. L., Takahashi, T. A., Fujihara, M. et al., Effects of ultraviolet B irradiation on cell-cell interaction; implication of morphological changes and actin filaments in irradiated cells, Clin. Exp. Immunol., 1996, 105(2): 389-396.
32. Schafer, C., Ross, S. E., Bragado, M. J. et al., A role for the p38 mitogen-activated protein kinase/Hsp 27 pathway in cholecystokinin-induced changes in the actin cytoskeleton in rat pancreatic acini, J. Biol. Chem., 1998, 273(37): 24173-24180.
33. den-Hartigh, J. C., van-Bergen-en-Henegouwen, P. M., Verkleij, A. J. et al., The EGF receptor is an actin-binding protein, J. Cell Biol., 1992, 119(2): 349-355.
34. Rijken, P. J., van-Hal, G. J., van-der-Heyden, M. A. et al., Actin polymerization is required for negative feedback regulation of epidermal growth factor-induced signal transduction, Exp. Cell Res., 1998, 243(2): 254-262.