Cotylenin A-induced differentiation is independent of the transforming growth factor-β signaling system in human myeloid leukemia HL-60 cells

Leukemia and Lymphoma

Volumn 47, Issue 4, 2006, Pages 733-740

  Matsunawa, Manabu ^a,b   Ishii, Yuki ^a   Kasukabe, Takashi ^a   Tomoyasu, Shigeru ^b   Ota, Hidekazu ^b   Honma, Yoshio ^a,c  

^a SAITAMA CANCER CENTER   (Japan)

^b SHOWA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c SHIMANE UNIVERSITY FACULTY OF MEDICINE   (Japan)

Author keywords

Cotylenin A; Differentiation; HL 60; Myeloid leukemia; Smad; Transforming growth factor ; Vitamin D3

Indexed keywords

CALCITRIOL; COTYLENIN A; DITERPENOID; RETINOIC ACID; SMAD PROTEIN; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA ANTIBODY; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER GROWTH; CANCER INHIBITION; CELL DIFFERENTIATION; CELL STRAIN HL 60; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DRUG POTENCY; DRUG POTENTIATION; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; MYELOID LEUKEMIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION;

CELL DIFFERENTIATION; CELL LINE, TUMOR; DITERPENES; GENE EXPRESSION REGULATION, NEOPLASTIC; HL-60 CELLS; HUMANS; IMMUNOHISTOCHEMISTRY; LEUKEMIA, MYELOCYTIC, ACUTE; MODELS, BIOLOGICAL; RNA, MESSENGER; SIGNAL TRANSDUCTION; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; U937 CELLS;

EID: 33646776072     PISSN: 10428194     EISSN: 10292403     Source Type: Journal    
DOI: 10.1080/10428190500375839     Document Type: Article

References (36)

1. Sassa, T and Tojyo, T and Munakata, K. (1970) Isolation of a new plant growth substance with cytokinin-like activity Nature, 227, pp. 379.
2. Sassa, T and Togashi, M and Kitaguchi, T. (1975) The structures of cotylenins A, B, C, D and E Agric Biol Chem, 39, pp. 1735-1744.
3. Sassa, T and Ooi, T and Nukina, M and Ikeda, M and Kato, N. (1998) Structural confirmation of cotylenin A, a novel fusicoccane-diterpene glycoside with potent plant growth-regulating activity from Cladosporium fungus sp. 501-7W Biosci Biotechnol Biochem, 62, pp. 1815-1818.
4. Asahi, K and Honma, Y and Hazeki, K and Sassa, T and Kubohara, Y and Sakurai, A and et al. (1997) Cotylenin A, a plant-growth regulator, induces the differentiation in murine and human myeloid leukemia cells Biochem Biophys Res Commun, 238, pp. 758-763.
5. Yamamoto-Yamaguchi, Y and Yamada, K and Ishii, Y and Asahi, K and Tomoyasu, S and Honma, Y. (2001) Induction of the monocytic differentiation of myeloid leukaemia cells by cotylenin A, a plant growth regulator Br J Haematol, 112, pp. 697-705.
6. Yamada, K and Honma, Y and Asahi, K and Sassa, T and Hino, K and Tomoyasu, S. (2001) Differentiation of human acute myeloid leukaemia cells in primary culture in response to cotylenin A, a plant growth regulator Br J Haematol, 114, pp. 814-821.
7. Honma, Y and Ishii, Y and Sassa, T and Asahi, K. (2003) Treatment of human promyelocytic leukemia in the SCID mouse model with cotylenin A, an inducer of myelomonocytic differentiation of leukemia cells Leuk Res, 27, pp. 1019-1025.
8. Yen, A and Roberson, M and Varvayanis, S and Lee, A. (1998) Retinoic acid induced mitogen-activated protein (MAP)/extracellular signal-regulated kinase (ERK) kinase-dependent MAP kinase activation needed to elicit HL-60 cell differentiation and growth arrest Cancer Res, 58, pp. 3163-3172.
9. Bertagnolo, V and Neri, L and Marchisio, M and Mischiati, C and Capitani, S. (1999) Phosphoinositide 3-kinase activity is essential for all-trans retinoic acid-induced granulocytic differentiation of HL-60 cells Cancer Res, 59, pp. 542-546.
10. Ishii, Y and Kiyota, H and Sakai, S and Honma, Y. (2004) Induction of differentiation of human myeloid leukemia cells by jasmonates, plant hormones Leukemia, 18, pp. 1413-1419.
11. Ishii, Y and Sakai, S and Honma, Y. (2003) Cytokinin-induced differentiation of human myeloid leukemia HL-60 cells is associated with the formation of nucleotide, but not with incorporation into DNA or RNA Biochim Biophys Acta, 1643, pp. 11-24.
12. Massague, J. (2000) How cells read TGF-β signals Nature Rev Mol Cell Biol, 1, pp. 169-178.
13. Siegel, P and Massague, J. (2003) Cytostatic and apoptotic actions of TGF-β in homeostasis and cancer Nature Rev Cancer, 3, pp. 807-821.
14. De Benedetti, F and Falk, L and Ellingsworth, L and Ruscetti, F and Faltynek, C. (1990) Synergy between transforming growth factor-β and tumor necrosis factor-α in the induction of monocytic differentiation of human leukemic cell lines Blood, 75, pp. 626-632.
15. Testa, U and Masciulli, R and Tritarelli, E and Pustorino, R and Marian, G and Martucci, R and et al. (1993) Transforming growth factor-β potentiates vitamin D3-induced terminal monocytic differentiation of human leukemic cell lines J Immunol, 150, pp. 2418-2430.
16. Falk, L and De Benedetti, F and Lohrey, N and Birchenall-Roberts, M and Ellingsworth, L and Faltynek, C. (1991) Induction of transforming growth factor-β1 (TGF-β1) receptor expression and TGF-β1 protein production in retinoic acid-treated HL-60 cells: Possible TGF-β1-mediated autocrine inhibition Blood, 77, pp. 1248-1255.
17. Turley, J and Falk, L and Ruscetti, F and Kasper, J and Francomano, T and Fu, T and et al. (1996) Transforming growth factor-β1 functions in monocytic differentiation of hematopoietic cells through autocrine and paracrine mechanisms Cell Growth Differ, 7, pp. 1535-1544.
18. Numes, I and Kojima, S and Rifkin, D. (1996) Effects of endogenously activated transforming growth factor-β on growth and differentiation of retinoic acid-treated HL-60 cells Cancer Res, 56, pp. 495-499.
19. Defacque, H and Piquemal, D and Basset, A and Marti, J and Commes, T. (1999) Transforming growth factor-β1 is an autocrine mediator of U937 cell growth arrest and differentiation induced by vitamin D3 and retinoids J Cell Physiol, 178, pp. 109-119.
20. Cao, Z and Flanders, K and Bertolette, D and Lyakh, L and Wurthner, J and Parks, W and et al. (2003) Levels of phospho-Smad2/3 are sensors of the interplay between effects of TGF-β and retinoic acid on monocytic and granulocytic differentiation of HL-60 cells Blood, 101, pp. 498-507.
21. Makishima, M and Kanatani, Y and Yamamoto-Yamaguchi, Y and Honma, Y. (1996) Enhancement of activity of 1,25-dihydroxyvitamin D3 for growth inhibition and differentiation induction of human myelomonocytic leukemia cells by tretinoin tocoferil, an α-tocopherol ester of all-trans retinoic acid Blood, 87, pp. 3384-3394.
22. Yokoyama, A and Okabe-Kado, J and Sakashita, A and Maseki, N and Kaneko, Y and Hino, K and et al. (1996) Differentiation inhibitory factor nm23 as a new prognostic factor in acute monocytic leukemia Blood, 88, pp. 3555-3561.
23. Derynck, R and Zhang, Y. (2003) Smad-dependent and Smad-independent pathways in TGF-β family signalling Nature, 425, pp. 577-584.
24. Inman, G and Nicolas, F and Callahan, J and Harling, J and Gaster, L and Reith, A and et al. (2002) SB-431542 is a potent and specific inhibitor of transforming growth factor-β superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7 Mol Pharmacol, 62, pp. 65-74.
25. Laping, N and Grygielko, E and Mathur, A and Butter, S and Bomberger, J and Tweed, C and et al. (2002) Inhibition of transforming growth factor (TGF)-β1-induced extracellular matrix with a novel inhibitor of the TGF-β type I receptor kinase activity: SB-431542 Mol Pharmacol, 62, pp. 58-64.
26. Callahan, J and Burgess, J and Fornwald, J and Gaster, L and Harling, J and Harrington, F and et al. (2002) Identification of novel inhibitors of the transforming growth factor β1 (TGF-β1) type 1 receptor (ALK5) J Med Chem, 45, pp. 999-1001.
27. Hjelmeland, M and Hjelmeland, A and Sathornsumetee, S and Reese, E and Herbstreith, M and Laping, N and et al. (2004) SB-431542, a small molecule transforming growth factor-β-receptor antagonist, inhibits human glioma cell line proliferation and motility Mol Cancer Ther, 3, pp. 737-745.
28. 3 and transforming growth factor-β signaling requires binding of VDR and Smad3 proteins to their cognate DNA recognition elements J Biol Chem, 276, pp. 15741-1576.
29. Yanagisawa, J and Yanagi, Y and Masuhiro, Y and Sugawa, M and Watanabe, M and Kashiwagi, K and et al. (1999) Convergence of transforming growth factor-β and vitamin D signaling pathways on SMAD transcriptional coactivators Science, 283, pp. 1317-1321.
30. Hayashi, H and Abdollah, S and Qiu, Y and Cai, J and Xu, X and Grinnell, B and et al. (1997) The MAD-related protein Smad7 associates with the TGFβ receptor and functions as an antagonist of TGFβ signaling Cell, 89, pp. 1165-1173.
31. Imamura, T and Takase, M and Nishihara, A and Oeda, E and Hanai, J and Kawabata, M and et al. (1997) Smad6 inhibits signaling by the TGF-β superfamily Nature, 389, pp. 622-626.
32. Kavsak, P and Rasmussen, R and Causing, C and Bonni, S and Zhu, H and Thomse, G and et al. (2000) Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF β receptor for degradation Mol Cell, 6, pp. 1365-1375.
33. Oecking, C and Eckerskorn, C and Weiler, E. (1994) The fusicoccin receptor of plants is a member of the 14-3-3 superfamily of eukaryotic regulatory proteins FEBS Lett, 352, pp. 163-166.
34. Hermeking, H. (2003) The 14-3-3 cancer connection Nature Rev Cancer, 3, pp. 931-943.
35. McGonigle, S and Beall, M and Pearce, E. (2002) Eukaryotic initiation factor 2α subunit associates with TGFβ receptors and 14-3-3ε and acts as a modulator of the TGFβ response Biochemistry, 41, pp. 579-587.
36. Bunney, T and De Boer, A and Levin, M. (2003) Fusicoccin signaling reveals 14-3-3 protein function as a novel step in left-right patterning during amphibian embryogenesis Development, 130, pp. 4847-4858.