Evidence for functional protein interactions required for poliovirus RNA replication

Journal of Virology

Volumn 80, Issue 11, 2006, Pages 5327-5337

  Teterina, Natalya L ^a   Levenson, Eric ^a   Rinaudo, Mario S ^a   Egger, Denise ^b   Bienz, Kurt ^b   Gorbalenya, Alexander E ^c   Ehrenfeld, Ellie ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b UNIVERSITY OF BASEL   (Switzerland)

^c LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS PROTEIN;

ANIMAL CELL; ARTICLE; CELL STRAIN COS1; CHIMERA; COMPLEX FORMATION; HELA CELL; NONHUMAN; POLIOMYELITIS VIRUS; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; RHINOVIRUS; RNA REPLICATION; TWO HYBRID SYSTEM; VIROGENESIS; VIRUS GENOME; VIRUS MUTATION; VIRUS REPLICATION;

ANIMALS; CARRIER PROTEINS; CERCOPITHECUS AETHIOPS; COS CELLS; GENOME, VIRAL; POLIOVIRUS; RNA, VIRAL; VIRAL NONSTRUCTURAL PROTEINS;

HUMAN RHINOVIRUS SP.; MAMMALIA; POLIOVIRUS;

EID: 33646747895     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.02684-05     Document Type: Article

References (43)

1. Banerjee, R., A. Echeverri, and A. Dasgupta. 1997. Polioviras-encoded 2C polypeptide specifically binds to the 3′-terminal sequences of viral negative-strand RNA. J. Virol. 71:9570-9578.
2. Barco, A., and L. Carrasco. 1998. Identification of regions of poliovirus 2BC protein that are involved in cytotoxicity. J. Virol. 72:3560-3570.
3. Carrasco, L., R. Guinea, A. Irurzun, and A. Barco. 2002. Effects of viral replication on cellular membrane metabolism and function, p. 337-354. In B. L. Semler and E. Wimmer (ed.), Molecular biology of picornaviruses. ASM Press, Washington, D.C.
4. Cho, M. W., N. Teterina, D. Egger, K. Bienz, and E. Ehrenfeld. 1994. Membrane rearrangement and vesicle induction by recombinant poliovirus 2C and 2BC in human cells. Virology 202:129-145.
5. Cuconati, A., W. Xiang, F. Lahser, T. Pfister, and E. Wimmer. 1998. A protein linkage map of the P2 nonstructural proteins of poliovirus. J. Virol. 72:1297-1307.
6. de Jong, A. S., I. W. Schrama, P. H. Willems, J. M. Galama, W. J. Melchers, and F. J. van Kuppeveld. 2002. Multimerization reactions of coxsackievirus proteins 2B, 2C and 2BC: a mammalian two-hybrid analysis. J. Gen. Virol. 83:783-793.
7. Doedens, J. R., T. H. Giddings, Jr., and K. Kirkegaard. 1997. Inhibition of endoplasmic reticulum-to-Golgi traffic by poliovirus protein 3A: genetic and ultrastructural analysis. J. Virol. 71:9054-9064.
8. Doedens, J. R., and K. Kirkegaard. 1995. Inhibition of cellular protein secretion by poliovirus proteins 2B and 3A. EMBO J. 14:894-907.
9. Echeverri, A., R. Banerjee, and A. Dasgupta. 1998. Amino-terminal region of poliovirus 2C protein is sufficient for membrane binding. Virus Res. 54:217-223.
10. Echeverri, A. C., and A. Dasgupta. 1995. Amino terminal regions of poliovirus 2C protein mediate membrane binding. Virology 208:540-553.
11. Egger, D., R. Gosert, and K. Bienz. 2002. Role of cellular structures in viral RNA replication, p. 247-253. In B. L. Semler and E. Wimmer (ed.), Molecular biology of picornaviruses. ASM Press, Washington, D.C.
12. Egger, D., L. Pasamontes, R. Bolten, V. Boyko, and K. Bienz. 1996. Reversible dissociation of the poliovirus replication complex: functions and interactions of its components in viral RNA synthesis. J. Virol. 70:8675-8683.
13. Gorbalenya, A. E., E. V. Koonin, and Y. I. Wolf. 1990. A new superfamily of putative NTP-binding domains encoded by genomes of small DNA and RNA viruses. FEBS Lett. 262:145-148.
14. Haller, A. A., and B. L. Semler. 1995. Stem-loop structure synergy in binding cellular proteins to the 5′ noncoding region of poliovirus RNA. Virology 206:923-934.
15. Harris, J. R., and V. R. Racaniello. 2003. Changes in rhinovirus protein 2C allow efficient replication in mouse cells. J. Virol. 77:4773-4780.
16. Jurgens, C., and J. B. Flanegan. 2003. Initiation of poliovirus negative-strand RNA synthesis requires precursor forms of P2 proteins. J. Virol. 77:1075-1083.
17. Li, J.-P., and D. Baltimore. 1990. An intragenic revenant of a poliovirus 2C mutant has an uncoating defect. J. Virol. 64:1102-1107.
18. Miller, D. J., M. D. Schwartz, and P. Ahlquist. 2001. Flock house virus RNA replicates on outer mitochondrial membranes in Drosophila cells. J. Virol. 75:11664-11676.
19. Mirzayan, C., and E. Wimmer. 1994. Biochemical studies on poliovirus polypeptide 2C: evidence for ATPase activity. Virology 199:176-187.
20. Molla, A., K. S. Harris, A. V. Paul, S. H. Shin, J. Mugavero, and E. Wimmer. 1994. Stimulation of poliovirus proteinase 3Cpro-related proteolysis by the genome-linked protein VPg and its precursor 3AB. J. Biol. Chem. 269:27015-27020.
21. Paul, A. V. 2002. Possible unifying mechanism of picornavirus genome replication, p. 227-246. In B. L. Semler and E. Wimmer (ed.), Molecular biology of picornaviruses. ASM Press, Washington, D.C.
22. Paul, A. V., A. Molla, and E. Wimmer. 1994. Studies of a putative amphipathic helix in the N-terminus of poliovirus protein 2C. Virology 199:188-199.
23. Pfister, T., and E. Wimmer. 1999. Characterization of the nucleoside triphosphatase activity of poliovirus protein 2C reveals a mechanism by which guanidine inhibits poliovirus replication. J. Biol. Chem. 274:6992-7001.
24. Rodriguez, P. L., and L. Carrasco. 1995. Poliovirus protein 2C contains two regions involved in RNA binding activity. J. Biol. Chem. 270:10105-10112.
25. Rodriguez, P. L., and L. Carrasco. 1993. Poliovirus protein 2C has ATPase and GTPase activities. J. Biol. Chem. 268:8105-8110.
26. Rust, R. C., L. Landmann, R. Gosert, B. L. Tang, W. Hong, H. P. Hauri, D. Egger, and K. Bienz. 2001. Cellular COP11 proteins are involved in production of the vesicles that form the poliovirus replication complex. J. Virol. 75:9808-9818.
27. Strauss, D. M., L. W. Glustrom, and D. S. Wuttke. 2003. Towards an understanding of the poliovirus replication complex: the solution structure of the soluble domain of the poliovirus 3A protein. J. Mol. Biol. 330:225-234.
28. Suhy, D. A., T. H. Giddings, Jr., and K. Kirkegaard. 2000. Remodeling the endoplasmic reticulum by poliovirus infection and by individual viral proteins: an autophagy-like origin for virus-induced vesicles. J. Virol. 74:8953-8965.
29. Teterina, N. L., D. Egger, K. Bienz, D. M. Brown, B. L. Semler, and E. Ehrenfeld. 2001. Requirements for assembly of poliovirus replication complexes and negative-strand RNA synthesis. J. Virol. 75:3841-3850.
30. Teterina, N. L., A. E. Gorbalenya, D. Egger, K. Bienz, and E. Ehrenfeld. 1997. Poliovirus 2C protein determinants of membrane binding and rearrangements in mammalian cells. J. Virol. 71:8962-8972.
31. Teterina, N. L., A. E. Gorbalenya, D. Egger, K. Bienz, M. S. Rinaudo, and E. Ehrenfeld. 2006. Testing the modularity of the N-terminal amphipathic helix conserved in picornavirus 2C proteins and hepatitis C NS5A protein. Virology 344:453-467.
32. Teterina, N. L., W. D. Zhou, M. W. Cho, and E. Ehrenfeld. 1995. Inefficient complementation activity of poliovirus 2C and 3D proteins for rescue of lethal mutations. J. Virol. 69:4245-4254.
33. Tolskaya, E. A., L. I. Romanova, M. S. Kolesnikova, A. P. Gmyl, A. E. Gorbalenya, and V. I. Agol. 1994. Genetic studies on the poliovirus 2C protein, an NTPase-a plausible mechanism of guanidine effect on the 2C function and evidence for the importance of 2C oligomerization. J. Mol. Biol. 236:1310-1323.
34. Towner, J. S., D. M. Brown, J. H. Nguyen, and B. L. Semler. 2003. Functional conservation of the hydrophobic domain of polypeptide 3AB between human rhinovirus and poliovirus. Virology 314:432-442.
35. Towner, J. S., M. M. Mazanet, and B. L. Semler. 1998. Rescue of defective poliovirus RNA replication by 3AB-containing precursor polyproteins. J. Virol. 72:7191-7200.
36. Vance, L. M., N. Moscufo, M. Chow, and B. A. Heinz. 1997. Poliovirus 2C region functions during encapsidation of viral RNA. J. Virol. 71:8759-8765.
37. van Kuppeveld, F. J., W. J. Melchers, K. Kirkegaard, and J. R. Doedens. 1997. Structure-function analysis of coxsackie B3 virus protein 2B. Virology 227:111-118.
38. van Kuppeveld, F. J., P. J. van den Hurk, W. van der Vliet, J. M. Galama, and W. J. Melchers. 1997. Chimeric coxsackie B3 virus genomes that express hybrid coxsackievirus-poliovirus 2B proteins: functional dissection of structural domains involved in RNA replication. J. Gen. Virol. 78:1833-1840.
39. van Kuppeveld, F. J. M., J. M. D. Galama, J. Zoll, and W. J. G. Melchers. 1995. Genetic analysis of a hydrophobic domain of coxsackie B3 virus protein 2B; a moderate degree of hydrophobicity is required for a cis-acting function in viral RNA synthesis. J. Virol. 69:7782-7790.
40. van Kuppeveld, F. J. M., J. M. D. Galama, J. Zoll, P. J. J. C. van der Hurk, and W. J. G. Melchers. 1996. Coxsackie B3 virus protein 2B contains a cationic amphipathic helix that is required for viral replication. J. Virol. 70:3876-3886.
41. Vaynberg, J., T. Fukuda, K. Chen, O. Vinogradova, A. Velyvis, Y. Tu, L. Ng, C. Wu, and J. Qin. 2005. Structure of an ultraweak protein-protein complex and its crucial role in regulation of cell morphology and motility. Mol. Cell 17:513-523.
42. Xiang, W., A. Cuconati, D. Hope, K. Kirkegaard, and E. Wimmer. 1998. Complete protein linkage map of poliovirus P3 proteins: interaction of polymerase 3Dpol with VPg and with genetic variants of 3AB. J. Virol. 72:6732-6741.
43. Zell, R., S. Seitz, A. Henke, T. Munder, and P. Wutzler. 2005. Linkage map of protein-protein interactions of porcine teschovirus. J. Gen. Virol. 86:2763-2768.