Retention of structural and functional polarity in cultured skate hepatocytes undergoing in vitro morphogenesis

Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology

Volumn 144, Issue 2, 2006, Pages 167-179

  Ballatori, Nazzareno ^a   Henson, John H ^b   Seward, David J ^a   Cai, Shi Ying ^c   Runnegar, Maria ^d   Fricker, Gert ^e   Miller, David S ^f,g   Boyer, James L ^c  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

^b DICKINSON COLLEGE   (United States)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^e Institut fur Pharmazeutische Technologie und Biopharmazie   (Germany)

^f NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^g MOUNT DESERT ISLAND BIOLOGICAL LABORATORY   (United States)

Author keywords

ATP; Bile secretion; Bsep; Glutathione; Membrane transport; Mrp2; Oatp; Polarized hepatocyte culture model

Indexed keywords

ACTIN; ADENOSINE TRIPHOSPHATE; ANION TRANSPORT PROTEIN; BILE SALT; CYTOCHROME P450; DEXAMETHASONE; FLUORESCEIN; GLUTATHIONE; MESSENGER RNA; METHOTREXATE; MULTIDRUG RESISTANCE PROTEIN 2; POTASSIUM ION; PROPIDIUM IODIDE; TRYPAN BLUE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BILE SECRETION; ELECTRIC FISH; IN VITRO STUDY; LIVER CELL CULTURE; MALE; MAMMAL; MEMBRANE TRANSPORT; MICROTUBULE; MORPHOGENESIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION;

ANIMALIA; LEUCORAJA ERINACEA; MAMMALIA;

EID: 33646673832     PISSN: 10964959     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbpb.2006.02.005     Document Type: Article

References (46)

1. Alpini G., Phillips J.O., Vroman B., and LaRusso N.F. Recent advances in the isolation of liver cells. Hepatology 20 (1994) 494-514
2. Amicone L., Spagnoli F.M., Spath G., Giordano S., Tommasini C., Bernardini S., De Luca V., Della Rocca C., Weiss M.C., Comoglio P.M., and Tripodi M. Transgenic expression in the liver of truncated Met blocks apoptosis and permits immortalization of hepatocytes. EMBO J. 16 (1997) 495-503
3. Baksi S.M., and Frazier J.M. Isolated fish hepatocytes: model systems for toxicology research. Aquat. Toxicol. 16 (1990) 229-256
4. Ballatori N., and Boyer J.L. Characteristics of l-alanine uptake in freshly isolated hepatocytes of elasmobranch Raja erinacea. Am. J. Physiol. 254 (1988) R801-R808
5. Ballatori N., and Boyer J.L. Disruption of cell volume regulation by mercuric chloride is mediated by an increase in sodium permeability and inhibition of an osmolyte channel in skate hepatocytes. Toxicol. Appl. Pharmacol. 140 (1996) 404-410
6. Ballatori N., and Villalobos A.R. Defining the molecular and cellular basis of toxicity using comparative models. Toxicol. Appl. Pharmacol. 183 (2002) 207-220
7. Ballatori N., Simmons T.W., and Boyer J.L. A volume-activated taurine channel in skate hepatocytes: membrane polarity and role of intracellular ATP. Am. J. Physiol. 267 (1994) G285-G291
8. Ballatori N., Truong A.T., Jackson P.S., Strange K., and Boyer J.L. ATP depletion and inactivation of an ATP-sensitive taurine channel by classic ion channel blockers. Mol. Pharmacol. 48 (1995) 472-476
9. Ballatori N., Hager D.N., Nundy S., Miller D.S., and Boyer J.L. Carrier-mediated uptake of lucifer yellow in skate and rat hepatocytes: a fluid-phase marker revisited. Am. J. Physiol. 277 (1999) G896-G904
10. Ballatori N., Connolly G.C., and Boyer J.L. Elasmobranch hepatocytes. In: Berry M.N., and Edwards A.M. (Eds). The Hepatocyte Review (2000), Kluwer, The Netherlands 37-47 Chapter 5
11. Berry M.N., Halls H.J., and Grivell M.B. Techniques for pharmacological and toxicological studies with isolated hepatocyte suspensions. Life Sci. 51 (1992) 1-16
12. Boyer J.L., Schwarz J., and Smith N. Biliary secretion in elasmobranchs. II. Hepatic uptake and biliary excretion of organic anions. Am. J. Physiol. 230 (1976) 974-981
13. Buck L.T., Land S.C., and Hochachka P.W. Anoxia-tolerant hepatocytes: model system for study of reversible metabolic suppression. Am. J. Physiol. 265 (1993) R49-R56
14. Burke M.D., Thompson S., Elcombe C.R., Halpert J., Haaparanta T., and Mayer R.T. Ethoxy-, pentoxy- and benzyloxyphenoxazones and homologues: a series of substrates to distinguish between different induced cytochromes P-450. Biochem. Pharmacol. 34 (1985) 3337-3345
15. Cai S.-Y., Wang L., Ballatori N., and Boyer J.L. Bile salt export pump is highly conserved during vertebrate evolution and its expression is inhibited by PFIC Type II mutations. Am. J. Physiol. 281 (2001) G316-G322
16. Cai S.-Y., Soroka C.J., Ballatori N., and Boyer J.L. Molecular characterization of a multidrug resistance-associated protein from the little skate, Raja erinacea. Am. J. Physiol. 284 (2003) R125-R130
17. Dranoff J.A., O'Neill A.F., Franco A.M., Cai S.-Y., Connolly G.C., Ballatori N., Boyer J.L., and Nathanson M.H. A primitive ATP receptor from the little skate Raja erinacea. J. Biol. Chem. 275 (2000) 30701-30706
18. Ferraris M., Radice S., Catalani P., Francolini M., Marabini L., and Chiesara E. Early oxidative damage in primary cultured trout hepatocytes: a time course study. Aquat. Toxicol. 59 (2002) 283-296
19. Fricker G., Dubost V., Finsterwald K., and Boyer J.L. Characteristics of bile salt uptake into skate hepatocytes. Biochem. J. 299 (1994) 665-670
20. Gjessing R., and Seglen P.O. Adsorption, simple binding and complex binding of rat hepatocytes to various in vitro substrata. Exp. Cell Res. 129 (1980) 239-249
21. Griffith O.W. Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine. Anal. Biochem. 106 (1980) 207-212
22. Grant M.H., Melvin M.A., Shaw P., Melvin W.T., and Burke M.D. Studies on the maintenance of cytochromes P-450 and b5, monooxygenases and cytochrome reductases in primary cultures of rat hepatocytes. FEBS Lett. 190 (1985) 99-103
23. Habig W.H., Pabst M.J., and Jakoby W.B. Glutathione S-transferases. The first enzymatic step in mercapturic acid formation. J. Biol. Chem. 249 (1974) 7130-7139
24. Henson J.H., Capuano S., Nesbitt D., Hager D.N., Nundy S., Miller D.S., Ballatori N., and Boyer J.L. Cytoskeletal organization in clusters of isolated polarized skate hepatocytes: structural and functional evidence for microtubule-dependent transcytosis. J. Exp. Zool. 271 (1995) 273-284
25. Hill M., Dupaix A., Volfin P., Kurkdjian A., and Arrio B. High performance liquid chromatography for simultaneous kinetic measurements of adenine nucleotides in isolated vacuoles. Methods Enzymol. 148 (1987) 132-141
26. Jackson P.S., Churchwell K., Ballatori N., Boyer J.L., and Strange K. Swelling-activated anion conductance in skate hepatocytes: regulation by cell chloride and ATP. Am. J. Physiol. 270 (1996) C57-C66
27. Klaunig J.E., Ruch R.J., and Goldblatt P.J. Trout hepatocyte culture: isolation and primary culture. In Vitro Cell. Dev. Biol. 21 (1985) 221-228
28. LeCluyse E.L., Audus K.L., and Hochman J.H. Formation of extensive canalicular networks by rat hepatocytes cultured in collagen-sandwich configuration. Am. J. Physiol. 266 (1994) C1764-C1774
29. Lee C.H., Bradley G., Zhang J.T., and Ling V. Differential expression of P-glycoprotein genes in primary rat hepatocyte culture. J. Cell. Physiol. 157 (1993) 392-402
30. Lowry O.H., Rosebrough N.J., Farr A.L., and Randall R.J. Protein measurement with the folin phenol reagent. J. Biol. Chem. 193 (1951) 265-275
31. Luttringer O., Theil F.P., Lave T., Wernli-Kuratli K., Guentert T.W., and de Saizieu A. Influence of isolation procedure, extracellular matrix and dexamethasone on the regulation of membrane transporters gene expression in rat hepatocytes. Biochem. Pharmacol. 64 (2002) 1637-1650
32. Milkiewicz P., Roma M.G., Elias E., and Coleman R. Pathobiology and experimental therapeutics in hepatocellular cholestasis: lessons from the hepatocyte couplet model. Clin. Sci. (Lond.) 102 (2002) 603-614
33. Miller D.S., Fricker G., Henson J.H., Hager D.N., Nundy S., Ballatori N., and Boyer J.L. Active, microtubule-dependent secretion of a fluorescent bile salt derivative in skate hepatocyte clusters. Am. J. Physiol. 270 (1996) G887-G896
34. Moon T.W., Walsh P.J., and Mommsen T.P. Fish hepatocytes: a model metabolic system. Can. J. Fish Aquat. Sci. 42 (1985) 1772-1782
35. Otsu K., Ito K., Kuzumaki T., and Iuchi Y. Differential regulation of liver-specific and ubiquitously-expressed genes in primary rat hepatocytes by the extracellular matrix. Cell. Physiol. Biochem. 11 (2001) 33-40
36. Plass J.R., Mol O., Heegsma J., Geuken M., Faber K.N., Jansen P.L., and Muller M. Farnesoid X receptor and bile salts are involved in transcriptional regulation of the gene encoding the human bile salt export pump. Hepatology 35 (2002) 589-596
37. Rippin S.J., Hagenbuch B., Meier P.J., and Stieger B. Cholestatic expression pattern of sinusoidal and canalicular organic anion transport systems in primary cultured rat hepatocytes. Hepatology 33 (2001) 776-782
38. Runnegar M., Seward D.J., Ballatori N., Crawford J.M., and Boyer J.L. Hepatic toxicity and persistence of ser/thr protein phosphatase inhibition by microcystin in the little skate Raja erinacea. Toxicol. Appl. Pharmacol. 161 (1999) 40-49
39. Schneider S., Schramm U., Schreyer A., Buscher H.P., Gerok W., and Kurz G. Fluorescent derivatives of bile salts. I. Synthesis and properties of NBD-amino derivatives of bile salts. J. Lipid Res. 32 (1991) 1769-1779
40. Schuetz J.D., and Schuetz E.G. Extracellular matrix regulation of multidrug resistance in primary monolayer cultures of adult rat hepatocytes. Cell Growth Differ. 4 (1993) 31-40
41. Seglen P.O. Preparation of isolated rat liver cells. Methods Cell Biol. 13 (1976) 29-83
42. Segner H., and Cravedi J.P. Metabolic activity in primary cultures of fish hepatocytes. Altern. Lab. Anim. 29 (2001) 251-257
43. Schippers I.J., Moshage H., Roelofsen H., Muller M., Heymans H.S., Ruiters M., and Kuipers F. Immortalized human hepatocytes as a tool for the study of hepatocytic de-differentiation. Cell Biol. Toxicol. 13 (1997) 375-386
44. Smith D.J., Grossbard M., Gordon E.R., and Boyer J.L. Isolation and characterization of a polarized isolated hepatocyte preparation in the skate (Raja erinacea). J. Exp. Zool. 241 (1987) 291-296
45. Tietze F. Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues. Anal. Biochem. 27 (1969) 502-522
46. Valentich J.D. Primary cultures of shark rectal gland epithelial cells: a model for hormone-sensitive chloride transport. J. Tissue Cult. Methods 13 (1991) 149-163