Solid-phase synthesis and preliminary evaluation of 1,6,8-trisubstituted tetrahydro-2H-pyrazino[1,2-a]pyrimidine-4,7-diones as a NF-kB inhibitor

Bulletin of the Korean Chemical Society

Volumn 27, Issue 4, 2006, Pages 484-488

  Kim, Jin Woong ^a   Cho, Jung Hyuck ^a   Han, Taehee ^b   Lee, JongBaek ^c   Oh, Chang Hyun ^a,b,c  

^a Korea Institute of Science and Technology   (South Korea)

^b Hawon Pharm Co   (South Korea)

^c Dong Eui University   (South Korea)

Author keywords

Bicyclic turn mimetics; NF kB inhibitor; Solid phase

Indexed keywords

ENZYME INHIBITION; HYDROCARBONS; REACTION KINETICS; SYNTHESIS (CHEMICAL);

BICYCLIC Β-TURN MIMETICS; FLUOROBENZYL; INHIBITION ACTIVITIES; NF-KB INHIBITOR; SOLID PHASE; SOLID-PHASE SYNTHESIS;

ORGANIC COMPOUNDS;

EID: 33646592257     PISSN: 02532964     EISSN: 12295949     Source Type: Journal    
DOI: 10.5012/bkcs.2006.27.4.484     Document Type: Article

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