Blaise reaction of ethyl 3-bromodifluoromethyl-3-benzyloxyacrylate with nitriles: A convenient synthesis of α-difluorovinyl-substituted β-enaminoesters and β-ketoesters

Synthesis

Volumn , Issue 9, 2006, Pages 1470-1474

  Peng, Weimin ^a,b   Zhao, Jingwei ^a   Zhu, Shizheng ^a  

^a SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY   (China)

^b UNIVERSITY OF KANSAS   (United States)

Author keywords

enaminoesters; ketoester; Blaise reaction; Nitrile; Zinc dienolate

Indexed keywords

ACYLATION; ESTERS; ETHYLENE; HYDROLYSIS; NITRILE RESINS; OXYGEN; REACTION KINETICS; SYNTHESIS (CHEMICAL); ZINC;

Β-ENAMINOESTERS; Β-KETOESTER; BLAISE REACTION; ZINC DIENOLATE;

BROMINE COMPOUNDS;

ACRYLIC ACID DERIVATIVE; ALPHA DIFLUOROVINYL BETA ENAMINOESTER DERIVATIVE; BETA KETOESTER DERIVATIVE; CHLORIDE; ESTER DERIVATIVE; ETHYL 3 BROMODIFLUOROMETHYL 3 BENZYLOXYACRYLATE; ETHYLENE DERIVATIVE; NITRILE; TETRAKIS(DIMETHYLAMINO)ETHYLENE; UNCLASSIFIED DRUG; ZINC DERIVATIVE; ZINC DIENOLATE;

ADDITION REACTION; ARTICLE; CHEMICAL REACTION; CHEMICAL STRUCTURE; HYDROLYSIS; SYNTHESIS;

EID: 33646590030     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2006-926436     Document Type: Article

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