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Volumn 38, Issue 3, 1997, Pages 443-446

A simple and highly efficient synthesis of β-amino-α, β-unsaturated ester via sonochemical Blaise reaction

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID DERIVATIVE; BETA AMINO ACID; ESTER;

EID: 0031023976     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(96)02321-0     Document Type: Article
Times cited : (72)

References (30)
  • 11
    • 0343874528 scopus 로고    scopus 로고
    • The bath should be filled with water containing some 3-5% detergent. In our laboratory, we use Decon 90 which permits much more even cavitation in the bath water
    • The bath should be filled with water containing some 3-5% detergent. In our laboratory, we use Decon 90 which permits much more even cavitation in the bath water.
  • 13
    • 0003467672 scopus 로고
    • March, John Wiley & Sons: New York
    • March, J. Advanced Organic Chemistry, 4th ed., John Wiley & Sons: New York, 1992, 931. The formation and structure of the condensation compound is described and shown on this page.
    • (1992) Advanced Organic Chemistry, 4th Ed. , vol.931
    • March, J.1
  • 26
    • 0343874526 scopus 로고    scopus 로고
    • note
    • A solution of zinc (5.0 mmol), 1,2-dibromoethane (1.1 mmol), acetonitrile (1.0 mmol) and ethyl bromoacetate (1.2 mmol) in 4 mL dry THF was sonicated for two hours and the major product was a self-condensation compound as well as the desired product which had a 15% yield.
  • 27
    • 0342568749 scopus 로고    scopus 로고
    • 1H-NMR
    • 1H-NMR.
  • 30
    • 0343874521 scopus 로고    scopus 로고
    • note
    • 2 (0.5 mmol), 2-bromobenzonitrile (1.0 mmol) and ethyl bromoacetate (1.0 mmol) in 4 mL dry THF was sonicated for two hours and β-amino ester (Entry 8) was produced with a 60% yield and a small amount of self-condensation compound.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.