메뉴 건너뛰기




Volumn 15, Issue 3, 2006, Pages 251-265

Neural repair strategies for Parkinson's disease: Insights from primate models

Author keywords

Animal models; Nonhuman primates; Parkinson's disease; Therapeutics

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; DOPAMINE; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; MANEB; OXIDOPAMINE; PARAQUAT; ROTENONE;

EID: 33646576182     PISSN: 09636897     EISSN: None     Source Type: Journal    
DOI: 10.3727/000000006783982025     Document Type: Review
Times cited : (45)

References (124)
  • 1
    • 0035353725 scopus 로고    scopus 로고
    • Frequency of levodopa-related dyskinesias and motor fluctuations as estimated from the cumulative literature
    • Ahlskog, J. E.; Muenter, M. D. Frequency of levodopa-related dyskinesias and motor fluctuations as estimated from the cumulative literature. Mov. Disord. 16(3):448-458; 2001.
    • (2001) Mov. Disord. , vol.16 , Issue.3 , pp. 448-458
    • Ahlskog, J.E.1    Muenter, M.D.2
  • 2
    • 0027236406 scopus 로고
    • Chronic administration of 1-methyl-4-phenyl-1,1,2,3,6-tetrahydropyrindine to monkeys: Behavioral, morphological and biochemical correlates
    • Albanese, A.; Granata, R.; Gregori, B.; Piccardi, M.; Colosimo, C.; Tonali, P. Chronic administration of 1-methyl-4-phenyl-1,1,2,3,6- tetrahydropyrindine to monkeys: behavioral, morphological and biochemical correlates. Neuroscience 55:823-832; 1993.
    • (1993) Neuroscience , vol.55 , pp. 823-832
    • Albanese, A.1    Granata, R.2    Gregori, B.3    Piccardi, M.4    Colosimo, C.5    Tonali, P.6
  • 3
    • 33646582054 scopus 로고    scopus 로고
    • Pharmacologic management of parkinsonism and other movement disorders
    • Katzung, B. G., ed. New York: McGraw Hill
    • Aminoff, M. J. Pharmacologic management of parkinsonism and other movement disorders. In: Katzung, B. G., ed. Basic and clinical pharmacology, 9th ed. New York: McGraw Hill; 2004.
    • (2004) Basic and Clinical Pharmacology, 9th Ed.
    • Aminoff, M.J.1
  • 4
    • 0028220186 scopus 로고
    • Behavioral assessment of the effects of embryonic nigral grafts in marmosets with unilateral 6-OHDA lesions of the nigrostriatal pathway
    • Annett, L. E.; Martel, F. L.; Rogers, D. C.; Ridley, R. M.; Baker, H. F.; Dunnett, S. B. Behavioral assessment of the effects of embryonic nigral grafts in marmosets with unilateral 6-OHDA lesions of the nigrostriatal pathway. Exp. Neurol. 125(2):228-246; 1994.
    • (1994) Exp. Neurol. , vol.125 , Issue.2 , pp. 228-246
    • Annett, L.E.1    Martel, F.L.2    Rogers, D.C.3    Ridley, R.M.4    Baker, H.F.5    Dunnett, S.B.6
  • 5
    • 0028940027 scopus 로고
    • A comparison of the behavioural effects of embryonic nigral grafts in the caudate nucleus and in the putamen of marmosets with unilateral 6-OHDA lesions
    • Annett, L. E.; Torres, E. M.; Ridley, R. M.; Baker, H. F.; Dunnett, S. B. A comparison of the behavioural effects of embryonic nigral grafts in the caudate nucleus and in the putamen of marmosets with unilateral 6-OHDA lesions. Exp. Brain Res. 103(3):355-371; 1995.
    • (1995) Exp. Brain Res. , vol.103 , Issue.3 , pp. 355-371
    • Annett, L.E.1    Torres, E.M.2    Ridley, R.M.3    Baker, H.F.4    Dunnett, S.B.5
  • 6
    • 0031455188 scopus 로고    scopus 로고
    • Survival of nigral grafts within the striatum of marmosets with 6-OHDA lesions depends critically on donor embryo age
    • Annett, L. E.; Torres, E. M.; Clarke, D. J.; Ishida, Y.; Barker, R. A.; Ridley, R. M.; Baker, H. F.; Dunnett, S. B. Survival of nigral grafts within the striatum of marmosets with 6-OHDA lesions depends critically on donor embryo age. Cell Transplant. 6(6):557-569; 1997.
    • (1997) Cell Transplant. , vol.6 , Issue.6 , pp. 557-569
    • Annett, L.E.1    Torres, E.M.2    Clarke, D.J.3    Ishida, Y.4    Barker, R.A.5    Ridley, R.M.6    Baker, H.F.7    Dunnett, S.B.8
  • 8
    • 0023634115 scopus 로고
    • Biochemical and behavioral correction of MPTP Parkinson-like syndrome by fetal cell transplantation
    • Bakay, R. A.; Barrow, D. L.; Fiandaca, M. S.; Iuvone, P. M.; Schiff, A.; Collins, D. C. Biochemical and behavioral correction of MPTP Parkinson-like syndrome by fetal cell transplantation. Ann. NY Acad. Sci. 495:623-640; 1987.
    • (1987) Ann. NY Acad. Sci. , vol.495 , pp. 623-640
    • Bakay, R.A.1    Barrow, D.L.2    Fiandaca, M.S.3    Iuvone, P.M.4    Schiff, A.5    Collins, D.C.6
  • 10
    • 0027937973 scopus 로고
    • Reversal of hemiparkinsonian syndrome in nonhuman primates by amnion implantation into caudate nucleus
    • Bankiewicz, K.; Palmatier, M.; Plunkett, R. J.; Cummins, A.; Oldfield, E. H. Reversal of hemiparkinsonian syndrome in nonhuman primates by amnion implantation into caudate nucleus. J. Neurosurg. 81:869-876; 1994.
    • (1994) J. Neurosurg. , vol.81 , pp. 869-876
    • Bankiewicz, K.1    Palmatier, M.2    Plunkett, R.J.3    Cummins, A.4    Oldfield, E.H.5
  • 12
    • 7444270637 scopus 로고    scopus 로고
    • Modulation of antioxidant defense systems by the environmental pesticide maneb in dopaminergic cells
    • Barlow, B. K.; Lee, D. W.; Cory-Slechta, D. A.; Opanashuk, L. A. Modulation of antioxidant defense systems by the environmental pesticide maneb in dopaminergic cells. Neurotoxicology 26(1):63-75; 2005.
    • (2005) Neurotoxicology , vol.26 , Issue.1 , pp. 63-75
    • Barlow, B.K.1    Lee, D.W.2    Cory-Slechta, D.A.3    Opanashuk, L.A.4
  • 14
    • 0035449393 scopus 로고    scopus 로고
    • Relationship between the appearance of symptoms and the level of nigrostriatal degeneration in a progressive 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine-lesioned macaque model of Parkinson's disease
    • Bezard, E.; Dovero, S.; Prunier, C.; Ravenscroft, P.; Chalon, S.; Guilloteau, D.; Crossman, A. R.; Bioulac, B.; Brotchie, J. M.; Gross, C. E. Relationship between the appearance of symptoms and the level of nigrostriatal degeneration in a progressive 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine- lesioned macaque model of Parkinson's disease. J. Neurosci. 21(17):6853-6861; 2001.
    • (2001) J. Neurosci. , vol.21 , Issue.17 , pp. 6853-6861
    • Bezard, E.1    Dovero, S.2    Prunier, C.3    Ravenscroft, P.4    Chalon, S.5    Guilloteau, D.6    Crossman, A.R.7    Bioulac, B.8    Brotchie, J.M.9    Gross, C.E.10
  • 15
    • 0017119186 scopus 로고
    • Growth of transplanted monoaminergic neurons into the adult hippocampus along the perforant path
    • Björklund, A.; Stenevi, U.; Svendgaard, N. Growth of transplanted monoaminergic neurons into the adult hippocampus along the perforant path. Nature 262(5571):787-790; 1976.
    • (1976) Nature , vol.262 , Issue.5571 , pp. 787-790
    • Björklund, A.1    Stenevi, U.2    Svendgaard, N.3
  • 16
    • 0037096220 scopus 로고    scopus 로고
    • Neural transplantation for treatment of Parkinson's disease
    • Borlongan, C. V.; Sanberg, P. R. Neural transplantation for treatment of Parkinson's disease. Drug Discov. Today 7(12):674-682; 2002.
    • (2002) Drug Discov. Today , vol.7 , Issue.12 , pp. 674-682
    • Borlongan, C.V.1    Sanberg, P.R.2
  • 20
    • 0001496694 scopus 로고
    • A primate model of parkinsonism: Selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3, 6-tetrahydorpyridine
    • Burns, R. S.; Chiueh, C. C.; Markey, S. P.; Ebert, M. H.; Jacobowitz, D. M.; Kopin, I. J. A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydorpyridine. Proc. Natl. Acad. Sci. USA 80:4546-4550; 1983.
    • (1983) Proc. Natl. Acad. Sci. USA , vol.80 , pp. 4546-4550
    • Burns, R.S.1    Chiueh, C.C.2    Markey, S.P.3    Ebert, M.H.4    Jacobowitz, D.M.5    Kopin, I.J.6
  • 21
    • 0028835734 scopus 로고
    • Increased dopamine clearance in the non-lesioned striatum of rhesus monkeys with unilateral 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) striatal lesions
    • Cass, W.; Gerhardt, G. A.; Zhang, Z.; Ovadia, A.; Gash, D. M. Increased dopamine clearance in the non-lesioned striatum of rhesus monkeys with unilateral 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) striatal lesions. Neurosci. Lett. 185:52-55; 1995.
    • (1995) Neurosci. Lett. , vol.185 , pp. 52-55
    • Cass, W.1    Gerhardt, G.A.2    Zhang, Z.3    Ovadia, A.4    Gash, D.M.5
  • 22
    • 20444380333 scopus 로고    scopus 로고
    • Subthalamic nucleus lesion reverses motor abnormalities and striatal glutamatergic overactivity in experimental parkinsonism
    • Centonze, D.; Gubellini, P.; Rossi, S.; Picconi, B.; Pisani, A.; Bernardi, G.; Calabresi, P.; Baunez, C. Subthalamic nucleus lesion reverses motor abnormalities and striatal glutamatergic overactivity in experimental parkinsonism. Neuroscience 133:831-840; 2005.
    • (2005) Neuroscience , vol.133 , pp. 831-840
    • Centonze, D.1    Gubellini, P.2    Rossi, S.3    Picconi, B.4    Pisani, A.5    Bernardi, G.6    Calabresi, P.7    Baunez, C.8
  • 23
    • 0036147103 scopus 로고    scopus 로고
    • Topographical localization of glial cell line-derived neurotrophic factor in the human brain stem: An immunohistochemical study of prenatal, neonatal and adult brains
    • Del Fiacco, M.; Quarto, M.; Serra, M. P.; Follesa, P.; Lai, M. L.; Bachis, A. Topographical localization of glial cell line-derived neurotrophic factor in the human brain stem: An immunohistochemical study of prenatal, neonatal and adult brains. J. Chem. Neuroanat. 23(1):29-48; 2002.
    • (2002) J. Chem. Neuroanat. , vol.23 , Issue.1 , pp. 29-48
    • Del Fiacco, M.1    Quarto, M.2    Serra, M.P.3    Follesa, P.4    Lai, M.L.5    Bachis, A.6
  • 24
    • 18844404686 scopus 로고    scopus 로고
    • Rotenone induces aggregation of gamma-tubulin protein and subsequent disorganization of the centrosome: Relevance to formation of inclusion bodies and neurodegeneration
    • Diaz-Corrales, F.; Asanuma, M.; Miyazaki, I.; Miyoshi, K.; Ogawa, N. Rotenone induces aggregation of gamma-tubulin protein and subsequent disorganization of the centrosome: Relevance to formation of inclusion bodies and neurodegeneration. Neuroscience 133(1):117-135; 2005.
    • (2005) Neuroscience , vol.133 , Issue.1 , pp. 117-135
    • Diaz-Corrales, F.1    Asanuma, M.2    Miyazaki, I.3    Miyoshi, K.4    Ogawa, N.5
  • 25
    • 0034114557 scopus 로고    scopus 로고
    • Relationship among nigrostriatal denervation, parkinsonism, and dyskinesias in the MPTP primate model
    • DiMonte, D. A.; McCormack, A.; Petzinger, G.; Janson, A. M.; Quik, M.; Langsten, W. J. Relationship among nigrostriatal denervation, parkinsonism, and dyskinesias in the MPTP primate model. Mov. Disord. 15(3):459-466; 2000.
    • (2000) Mov. Disord. , vol.15 , Issue.3 , pp. 459-466
    • Dimonte, D.A.1    McCormack, A.2    Petzinger, G.3    Janson, A.M.4    Quik, M.5    Langsten, W.J.6
  • 27
    • 0035839562 scopus 로고    scopus 로고
    • Subthalamic GAD gene transfer in Parkinson disease patients who are candidates for deep brain stimulation
    • During, M. J.; Kaplitt, M. G.; Stern, M. B.; Eidelberg, D. Subthalamic GAD gene transfer in Parkinson disease patients who are candidates for deep brain stimulation. Hum. Gene Ther. 12(12):1589-1591; 2001.
    • (2001) Hum. Gene Ther. , vol.12 , Issue.12 , pp. 1589-1591
    • During, M.J.1    Kaplitt, M.G.2    Stern, M.B.3    Eidelberg, D.4
  • 28
    • 0032738101 scopus 로고    scopus 로고
    • Striatal dopaminergic correlates of stable parkinsonism and degree of recovery in old-world primates one year after MPTP treatment
    • Elsworth, J. D.; Taylor, J. R.; Sladek, J. R.; Collier, T. J.; Redmond, D. E.; Roth, R. H. Striatal dopaminergic correlates of stable parkinsonism and degree of recovery in old-world primates one year after MPTP treatment. Neuroscience 95(2):399-408; 2000.
    • (2000) Neuroscience , vol.95 , Issue.2 , pp. 399-408
    • Elsworth, J.D.1    Taylor, J.R.2    Sladek, J.R.3    Collier, T.J.4    Redmond, D.E.5    Roth, R.H.6
  • 29
    • 0037204595 scopus 로고    scopus 로고
    • Migration patterns and phenotypic differentiation of long-term expanded human neural progenitor cells after transplantation into the adult rat brain
    • Englund, U.; Björklund, A.; Wictorin, K. Migration patterns and phenotypic differentiation of long-term expanded human neural progenitor cells after transplantation into the adult rat brain. Brain Res. Dev Brain Res. 134(1-2):123-141; 2002.
    • (2002) Brain Res. Dev. Brain Res. , vol.134 , Issue.1-2 , pp. 123-141
    • Englund, U.1    Björklund, A.2    Wictorin, K.3
  • 30
    • 0141449053 scopus 로고    scopus 로고
    • Sensorimotor deficits in a unilateral intrastriatal 6-OHDA partial lesion model of Parkinson's disease in marmoset monkeys
    • Eslamboli, A.; Baker, H.; Ridley, R.; Annett, L. Sensorimotor deficits in a unilateral intrastriatal 6-OHDA partial lesion model of Parkinson's disease in marmoset monkeys. Exp. Neurol. 183:418-429; 2003.
    • (2003) Exp. Neurol. , vol.183 , pp. 418-429
    • Eslamboli, A.1    Baker, H.2    Ridley, R.3    Annett, L.4
  • 31
    • 0345257314 scopus 로고    scopus 로고
    • Recombinant adeno-associated viral vector (rAAV) delivery of GDNF provides protection against 6-OHDA lesion in the common marmoset monkey (Callithrix jacchus)
    • Eslamboli, A.; Cummings, R. M.; Ridley, R. M.; Baker, H. F.; Muzyczka, N.; Burger, C.; Mandel, R. J.; Kirik, D.; Annett, L. E. Recombinant adeno-associated viral vector (rAAV) delivery of GDNF provides protection against 6-OHDA lesion in the common marmoset monkey (Callithrix jacchus). Exp. Neurol. 184(1):536-548; 2003.
    • (2003) Exp. Neurol. , vol.184 , Issue.1 , pp. 536-548
    • Eslamboli, A.1    Cummings, R.M.2    Ridley, R.M.3    Baker, H.F.4    Muzyczka, N.5    Burger, C.6    Mandel, R.J.7    Kirik, D.8    Annett, L.E.9
  • 32
    • 28144449393 scopus 로고    scopus 로고
    • Marmoset monkey models of Parkinson's disease. Which model, when and why?
    • Eslamboli, A. Marmoset monkey models of Parkinson's disease. Which model, when and why? Brain Res. Bull. 68:140-149; 2005.
    • (2005) Brain Res. Bull. , vol.68 , pp. 140-149
    • Eslamboli, A.1
  • 33
    • 0024042235 scopus 로고
    • Adrenal medullary tissue grafting in Parkinson's disease
    • Fiandaca, M. S.; Kordower, J. H.; Hansen, J. T.; Gash, D. M. Adrenal medullary tissue grafting in Parkinson's disease. J. Neurosurg. 69(1):150-152; 1988.
    • (1988) J. Neurosurg. , vol.69 , Issue.1 , pp. 150-152
    • Fiandaca, M.S.1    Kordower, J.H.2    Hansen, J.T.3    Gash, D.M.4
  • 35
    • 2342662120 scopus 로고    scopus 로고
    • Behavioral and immunohistochemical effects of chronic intravenous and subcutaneous infusions of varying doses of rotenone
    • Fleming, S. M.; Zhu, C.; Femagut, P. O.; Mehta, A.; Dicarlo, C. D.; Seaman, R. L.; Chesselet, M. F. Behavioral and immunohistochemical effects of chronic intravenous and subcutaneous infusions of varying doses of rotenone. Exp. Neurol. 187(2):418-429; 2004.
    • (2004) Exp. Neurol. , vol.187 , Issue.2 , pp. 418-429
    • Fleming, S.M.1    Zhu, C.2    Femagut, P.O.3    Mehta, A.4    Dicarlo, C.D.5    Seaman, R.L.6    Chesselet, M.F.7
  • 40
    • 0036787532 scopus 로고    scopus 로고
    • Chronic, controlled GDNF infusion promotes structural and functional recovery in advanced parkinsonian monkeys
    • Grondin, R.; Zhang, Z.; Yi, A.; Cass, W. A.; Maswood, N.; Andersen, A. H.; Elsberry, D. D.; Klein, M. C.; Gerhardt, G. A.; Gash, D. M. Chronic, controlled GDNF infusion promotes structural and functional recovery in advanced parkinsonian monkeys. Brain 125(Pt. 10):2191-2201; 2002.
    • (2002) Brain , vol.125 , Issue.PART 10 , pp. 2191-2201
    • Grondin, R.1    Zhang, Z.2    Yi, A.3    Cass, W.A.4    Maswood, N.5    Andersen, A.H.6    Elsberry, D.D.7    Klein, M.C.8    Gerhardt, G.A.9    Gash, D.M.10
  • 42
    • 0037338225 scopus 로고    scopus 로고
    • Stimulation of the subthalamic nucleus changes the firing pattern of pallidal neurons
    • Hashimoto, T.; Hder, C. M.; Okun, M. S.; Patrick, S. K.; Vitek, J. L. Stimulation of the subthalamic nucleus changes the firing pattern of pallidal neurons. J. Neurosci. 23(5):1916-1923; 2003.
    • (2003) J. Neurosci. , vol.23 , Issue.5 , pp. 1916-1923
    • Hashimoto, T.1    Hder, C.M.2    Okun, M.S.3    Patrick, S.K.4    Vitek, J.L.5
  • 44
    • 0025284697 scopus 로고
    • Does adrenal graft enhance recovery of dopaminergic neurons in Parkinson's disease?
    • Hirsch, E. C.; Duyckaerts, C.; Javoy-Agid, F.; Hauw, J. J.; Agid, Y. Does adrenal graft enhance recovery of dopaminergic neurons in Parkinson's disease? Ann. Neurol. 27(6):676-682; 1990.
    • (1990) Ann. Neurol. , vol.27 , Issue.6 , pp. 676-682
    • Hirsch, E.C.1    Duyckaerts, C.2    Javoy-Agid, F.3    Hauw, J.J.4    Agid, Y.5
  • 45
    • 0028619005 scopus 로고
    • Stereotactic neural transplantation
    • Hitchcock, E. Stereotactic neural transplantation. Stereotact. Funct. Neurosurg. 62(1-4):120-133; 1994.
    • (1994) Stereotact. Funct. Neurosurg. , vol.62 , Issue.1-4 , pp. 120-133
    • Hitchcock, E.1
  • 46
    • 0016140538 scopus 로고
    • Electrophysiological and cytological studies of brain homografts in the anterior chamber of the eye: Maturation of cerbellar cortex in oculo
    • Hoffer, B.; Seiger, A.; Ljungberg, T.; Olson, L. Electrophysiological and cytological studies of brain homografts in the anterior chamber of the eye: Maturation of cerbellar cortex in oculo. Brain Res. 79(2):165-184; 1974.
    • (1974) Brain Res. , vol.79 , Issue.2 , pp. 165-184
    • Hoffer, B.1    Seiger, A.2    Ljungberg, T.3    Olson, L.4
  • 47
    • 0017326472 scopus 로고
    • Electrophysiology and cytology of hippocampal formation transplants in the anterior chamber of the eye. II. Cholinergic mechanisms
    • Hoffer, B.; Seiger, A.; Freedman, R.; Olson, L.; Taylor, D. Electrophysiology and cytology of hippocampal formation transplants in the anterior chamber of the eye. II. Cholinergic mechanisms. Brain Res. 119(1):107-132; 1977.
    • (1977) Brain Res. , vol.119 , Issue.1 , pp. 107-132
    • Hoffer, B.1    Seiger, A.2    Freedman, R.3    Olson, L.4    Taylor, D.5
  • 48
    • 0242624508 scopus 로고    scopus 로고
    • Quantitative analysis of dopaminergic loss in relation to functional territories in MPTP-treated monkeys
    • Jan, C.; Pessiglione, M.; Tremblay, L.; Tande, D.; Hirsch, E. C.; Francois, C. Quantitative analysis of dopaminergic loss in relation to functional territories in MPTP-treated monkeys. Eur. J. Neurosci. 18:2082-2086; 2003.
    • (2003) Eur. J. Neurosci. , vol.18 , pp. 2082-2086
    • Jan, C.1    Pessiglione, M.2    Tremblay, L.3    Tande, D.4    Hirsch, E.C.5    Francois, C.6
  • 49
    • 20444489689 scopus 로고    scopus 로고
    • Motor fluctuations and dyskinesias in Parkinson's disease: Clinical manifestations
    • Jankovic, J. Motor fluctuations and dyskinesias in Parkinson's disease: Clinical manifestations. Mov. Disord. 20(Suppl. 11):S11-16; 2005.
    • (2005) Mov. Disord. , vol.20 , Issue.SUPPL. 11
    • Jankovic, J.1
  • 50
    • 0037269421 scopus 로고    scopus 로고
    • The contribution of the MPTP-treated primate model to the development of new treatment strategies for Parkinson's disease
    • Jenner, P. The contribution of the MPTP-treated primate model to the development of new treatment strategies for Parkinson's disease. Parkinsonism Relat. Disord. 9:131-137; 2003.
    • (2003) Parkinsonism Relat. Disord. , vol.9 , pp. 131-137
    • Jenner, P.1
  • 52
    • 0032143368 scopus 로고    scopus 로고
    • Characterization of behavioral and neurodegenerative changes following partial lesions of the nigrostriatal dopamine system induced by intrastriatal 6-hydroxydopamine in the rat
    • Kirik, D.; Rosenblad, C.; Björklund, A. Characterization of behavioral and neurodegenerative changes following partial lesions of the nigrostriatal dopamine system induced by intrastriatal 6-hydroxydopamine in the rat. Exp. Neurol. 152:259-277; 1998.
    • (1998) Exp. Neurol. , vol.152 , pp. 259-277
    • Kirik, D.1    Rosenblad, C.2    Björklund, A.3
  • 53
    • 0036550101 scopus 로고    scopus 로고
    • Parkinson-like neurodegeneration induced by targeted overexpression of α-synuclein in the nigrostriatal system
    • Kirik, D.; Rosenblad, C.; Burger, C.; Lundberg, C.; Johansen, T.; Muzycka, N.; Mandel, R.; Björklund, A. Parkinson-like neurodegeneration induced by targeted overexpression of α-synuclein in the nigrostriatal system. J. Neurosci. 22(7):2780-2791; 2002.
    • (2002) J. Neurosci. , vol.22 , Issue.7 , pp. 2780-2791
    • Kirik, D.1    Rosenblad, C.2    Burger, C.3    Lundberg, C.4    Johansen, T.5    Muzycka, N.6    Mandel, R.7    Björklund, A.8
  • 54
    • 0345269757 scopus 로고    scopus 로고
    • Nigrostriatal α-synucleinopathy induced by viral vector-mediated overexpression of human α-synuclein: A new primate model of Parkinson's disease
    • Kirik, D.; Annett, L.; Burger, C.; Muzyczka, N.; Mandel, R.; Björklund, A. Nigrostriatal α-synucleinopathy induced by viral vector-mediated overexpression of human α-synuclein: A new primate model of Parkinson's disease. Proc. Natl. Acad. Sci. USA 100(5):2884-2889; 2003.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , Issue.5 , pp. 2884-2889
    • Kirik, D.1    Annett, L.2    Burger, C.3    Muzyczka, N.4    Mandel, R.5    Björklund, A.6
  • 55
    • 0025757290 scopus 로고
    • Putative chromaffin cell survival and enhanced host-derived TH-fiber innervation following a functional adrenal medulla autograft for Parkinson's disease
    • Kordower, J. H.; Cochran, E.; Penn, R. D.; Goetz, C. G. Putative chromaffin cell survival and enhanced host-derived TH-fiber innervation following a functional adrenal medulla autograft for Parkinson's disease. Ann. Neurol. 29(4):405-412; 1991.
    • (1991) Ann. Neurol. , vol.29 , Issue.4 , pp. 405-412
    • Kordower, J.H.1    Cochran, E.2    Penn, R.D.3    Goetz, C.G.4
  • 58
    • 0034676997 scopus 로고    scopus 로고
    • MPTP induces alpha-synuclein aggregation in the substantia nigra of baboons
    • Kowall, N.; Hantraye, P.; Brouillet, E.; Beal, M. F.; McKee, A.; Ferrante, R. MPTP induces alpha-synuclein aggregation in the substantia nigra of baboons. Neuroreport 11(1):211-213; 2000.
    • (2000) Neuroreport , vol.11 , Issue.1 , pp. 211-213
    • Kowall, N.1    Hantraye, P.2    Brouillet, E.3    Beal, M.F.4    McKee, A.5    Ferrante, R.6
  • 59
    • 0034638413 scopus 로고    scopus 로고
    • Immunohistochemical localization of glial cell line-derived neurotrophic factor in the human central nervous system
    • Kowamoto, Y.; Nakamura, S.; Matsuo, A.; Akiguchi, I.; Shibasaki, H. Immunohistochemical localization of glial cell line-derived neurotrophic factor in the human central nervous system. Neuroscience 100(4):701-712; 2000.
    • (2000) Neuroscience , vol.100 , Issue.4 , pp. 701-712
    • Kowamoto, Y.1    Nakamura, S.2    Matsuo, A.3    Akiguchi, I.4    Shibasaki, H.5
  • 61
    • 0142152949 scopus 로고    scopus 로고
    • Parkinson's disease: Deep brain stimulation
    • Krack, P. Parkinson's disease: Deep brain stimulation. Rev. Neurol. (Paris) 158(122):135-141; 2002.
    • (2002) Rev. Neurol. (Paris) , vol.158 , Issue.122 , pp. 135-141
    • Krack, P.1
  • 62
    • 0034871806 scopus 로고    scopus 로고
    • Monoamine oxidase-inhibition and MPTP-induced neurotoxicity in the non-human primate: Comparison of rasagiline (TVP 1012) with segegiline
    • Kupsch, A.; Sautter, J.; Gotz, M. E.; Breithaupt, W.; Schwarz, J.; Youdim, M. B. H.; Riederer, P.; Gerlach, M.; Oertel, W. H. Monoamine oxidase-inhibition and MPTP-induced neurotoxicity in the non-human primate: Comparison of rasagiline (TVP 1012) with segegiline. J. Neural Transm. 108:985-1009; 2001.
    • (2001) J. Neural Transm. , vol.108 , pp. 985-1009
    • Kupsch, A.1    Sautter, J.2    Gotz, M.E.3    Breithaupt, W.4    Schwarz, J.5    Youdim, M.B.H.6    Riederer, P.7    Gerlach, M.8    Oertel, W.H.9
  • 63
    • 0020680904 scopus 로고
    • Chronic parkinsonism in humans due to a product of meperidine-analog synthesis
    • Langston, J.; Ballard, P.; Irwin, I. Chronic parkinsonism in humans due to a product of meperidine-analog synthesis. Science 219:979-980; 1983.
    • (1983) Science , vol.219 , pp. 979-980
    • Langston, J.1    Ballard, P.2    Irwin, I.3
  • 64
    • 0023807537 scopus 로고
    • The use of adrenal medullary and fetal grafts as a treatment for Parkinson disease
    • Lieberman, A. N. The use of adrenal medullary and fetal grafts as a treatment for Parkinson disease. NY State J. Med. 88(6):287-289; 1988.
    • (1988) NY State J. Med. , vol.88 , Issue.6 , pp. 287-289
    • Lieberman, A.N.1
  • 68
    • 0036679197 scopus 로고    scopus 로고
    • α-synucleinopathy and selective dopaminergic neuron loss in a rat lentiviral-based model of Parkinson's disease
    • Lo Bianco, C.; Ridet, J.; Schenider, B.; Deglon, N.; Aebischer, P. α-Synucleinopathy and selective dopaminergic neuron loss in a rat lentiviral-based model of Parkinson's disease. Proc. Natl. Acad. Sci. USA 99(16):10813-10818; 2002.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , Issue.16 , pp. 10813-10818
    • Lo Bianco, C.1    Ridet, J.2    Schenider, B.3    Deglon, N.4    Aebischer, P.5
  • 69
    • 5144225578 scopus 로고    scopus 로고
    • Lentiviral nigral delivery of GDNF does not prevent neurodegeneration in a genetic rat model of Parkinson's disease
    • Lo Bianco, C.; Deglon, N.; Pralong, W.; Aebischer, P. Lentiviral nigral delivery of GDNF does not prevent neurodegeneration in a genetic rat model of Parkinson's disease. Neurobiol. Dis. 17(2):283-289; 2004.
    • (2004) Neurobiol. Dis. , vol.17 , Issue.2 , pp. 283-289
    • Lo Bianco, C.1    Deglon, N.2    Pralong, W.3    Aebischer, P.4
  • 71
    • 0037127197 scopus 로고    scopus 로고
    • The herbicide paraquat causes up-regulation and aggregation of α-synuclein in mice
    • Manning-Bog, A.; McCormack, A.; Li, J.; Uversky, V.; Fink, A.; Di Monte, D. The herbicide paraquat causes up-regulation and aggregation of α-synuclein in mice. J. Biochem. 277(3):1641-1644; 2002.
    • (2002) J. Biochem. , vol.277 , Issue.3 , pp. 1641-1644
    • Manning-Bog, A.1    McCormack, A.2    Li, J.3    Uversky, V.4    Fink, A.5    Di Monte, D.6
  • 72
    • 0242693208 scopus 로고    scopus 로고
    • Spontaneous and evoked activity of substantia nigra pars reticulata neurons during high-frequency stimulation of subthalamic nucleus
    • Maurice, N.; Thierry, A. M.; Glowinski, J.; Deniau, J. M. Spontaneous and evoked activity of substantia nigra pars reticulata neurons during high-frequency stimulation of subthalamic nucleus. J. Neurosci. 23(30): L9929-9936; 2003.
    • (2003) J. Neurosci. , vol.23 , Issue.30
    • Maurice, N.1    Thierry, A.M.2    Glowinski, J.3    Deniau, J.M.4
  • 73
    • 26044453539 scopus 로고    scopus 로고
    • Subthalamic high frequency stimulation resets subthalamic firing and reduces abnormal oscillations
    • Meissner, W.; Leblois, A.; Hansel, D.; Bioulac, B.; Gross, C. E.; Benazzouz, A.; Boraud, T. Subthalamic high frequency stimulation resets subthalamic firing and reduces abnormal oscillations. Brain 128(Pt. 10):2372-2382; 2005.
    • (2005) Brain , vol.128 , Issue.PART 10 , pp. 2372-2382
    • Meissner, W.1    Leblois, A.2    Hansel, D.3    Bioulac, B.4    Gross, C.E.5    Benazzouz, A.6    Boraud, T.7
  • 74
    • 0032581386 scopus 로고    scopus 로고
    • Spontaneous regeneration of nigrostriatal dopaminergic neurons in MPTP-treated C57BL/6 mice
    • Mitsumoto, Y.; Watanabe, A.; Mori, A.; Koga, N. Spontaneous regeneration of nigrostriatal dopaminergic neurons in MPTP-treated C57BL/6 mice. Biochem. Biophys. Res. Commun. 248(3):660-663; 1998.
    • (1998) Biochem. Biophys. Res. Commun. , vol.248 , Issue.3 , pp. 660-663
    • Mitsumoto, Y.1    Watanabe, A.2    Mori, A.3    Koga, N.4
  • 75
    • 0021190231 scopus 로고
    • Adrenal medulla grafts survive and exhibit catecholamine-specific fluorescence in the primate brain
    • Morihisa, J. M.; Nakamura, R. K.; Freed, W. J.; Mishkin, M.; Wyatt, R. J. Adrenal medulla grafts survive and exhibit catecholamine-specific fluorescence in the primate brain. Exp. Neurol. 84(3):643-653; 1984.
    • (1984) Exp. Neurol. , vol.84 , Issue.3 , pp. 643-653
    • Morihisa, J.M.1    Nakamura, R.K.2    Freed, W.J.3    Mishkin, M.4    Wyatt, R.J.5
  • 76
    • 0028084486 scopus 로고
    • Improved graft survival and striatal reinnervation by microtransplantation of fetal nigral cell suspensions in the rat Parkinson model
    • Nikkhah, G.; Cunningham, M. G.; Jodicke, A.; Knappe, U.; Björklund, A. Improved graft survival and striatal reinnervation by microtransplantation of fetal nigral cell suspensions in the rat Parkinson model. Brain Res. 633(1-2):133-143; 1994.
    • (1994) Brain Res. , vol.633 , Issue.1-2 , pp. 133-143
    • Nikkhah, G.1    Cunningham, M.G.2    Jodicke, A.3    Knappe, U.4    Björklund, A.5
  • 77
    • 0028138846 scopus 로고
    • A microtransplantation approach for cell suspension grafting in the rat Parkinson model: A detailed account of the methodology
    • Nikkhah, G.; Olsson, M.; Eberhard, J. A microtransplantation approach for cell suspension grafting in the rat Parkinson model: A detailed account of the methodology. Neuroscience 63:57-72; 1994.
    • (1994) Neuroscience , vol.63 , pp. 57-72
    • Nikkhah, G.1    Olsson, M.2    Eberhard, J.3
  • 78
    • 0030768929 scopus 로고    scopus 로고
    • Genetics of Parkinson's disease
    • Nussbaum, R.; Polymeropoulous, M. Genetics of Parkinson's disease. Hum. Mol. Genet. 6(10):1687-1691; 1997.
    • (1997) Hum. Mol. Genet. , vol.6 , Issue.10 , pp. 1687-1691
    • Nussbaum, R.1    Polymeropoulous, M.2
  • 80
    • 0034703621 scopus 로고    scopus 로고
    • FGF-20, a novel neurotrophic factor, preferentially expressed in the substantia nigra pars compacta of rat brain
    • Ohmachi, S.; Watanabe, Y.; Mikami, T.; Kusu, N.; Ibi, T.; Akaike, A.; Itoh, N. FGF-20, a novel neurotrophic factor, preferentially expressed in the substantia nigra pars compacta of rat brain. Biochem. Biophys. Res. Commun. 277(2):355-360; 2000.
    • (2000) Biochem. Biophys. Res. Commun. , vol.277 , Issue.2 , pp. 355-360
    • Ohmachi, S.1    Watanabe, Y.2    Mikami, T.3    Kusu, N.4    Ibi, T.5    Akaike, A.6    Itoh, N.7
  • 81
    • 4043111360 scopus 로고    scopus 로고
    • Overlesioned hemiparkinsonian nonhuman primate model: Correlation between clinical, neurochemical and histochemical changes
    • Oiwa, Y.; Eberling, J. L.; Nigy, D.; Pivirotto, P.; Emborg, M. E.; Bankiewicz, K. Overlesioned hemiparkinsonian nonhuman primate model: Correlation between clinical, neurochemical and histochemical changes. Front. Biosci. 8:a155-166; 2003.
    • (2003) Front. Biosci. , vol.8
    • Oiwa, Y.1    Eberling, J.L.2    Nigy, D.3    Pivirotto, P.4    Emborg, M.E.5    Bankiewicz, K.6
  • 82
    • 0032936755 scopus 로고    scopus 로고
    • Etiology and pathogenesis of Parkinson's disease
    • Olanow, C. W.; Tatton, W. G. Etiology and pathogenesis of Parkinson's disease. Annu. Rev. Neurosci. 22:123-144; 1999.
    • (1999) Annu. Rev. Neurosci. , vol.22 , pp. 123-144
    • Olanow, C.W.1    Tatton, W.G.2
  • 84
    • 0015441424 scopus 로고
    • Early prenatal ontogeny of central monoamine neurons in the rat: Fluorescence histochemical observations
    • Olson, L.; Seiger, A. Early prenatal ontogeny of central monoamine neurons in the rat: Fluorescence histochemical observations. Z. Anat. Entwicklungsgesetz 137(3):301-316; 1972.
    • (1972) Z. Anat. Entwicklungsgesetz , vol.137 , Issue.3 , pp. 301-316
    • Olson, L.1    Seiger, A.2
  • 85
    • 0017232309 scopus 로고
    • Locus coeruleus: Fiber growth regulation in oculo
    • Olson, L.; Seiger, A. Locus coeruleus: fiber growth regulation in oculo. Med. Biol. 54(2):142-145; 1976.
    • (1976) Med. Biol. , vol.54 , Issue.2 , pp. 142-145
    • Olson, L.1    Seiger, A.2
  • 86
    • 29644447278 scopus 로고    scopus 로고
    • Rotenone model of Parkinson disease: Multiple brain mitochondria dysfunctions after short term systemic rotenone intoxication
    • Panov, A.; Dikalov, S.; Shalbuyeva, N.; Taylor, G.; Sherer, T.; Greenamyre, J. Rotenone model of Parkinson disease: Multiple brain mitochondria dysfunctions after short term systemic rotenone intoxication. J. Biol. Chem. 280(51):42026-42035; 2005.
    • (2005) J. Biol. Chem. , vol.280 , Issue.51 , pp. 42026-42035
    • Panov, A.1    Dikalov, S.2    Shalbuyeva, N.3    Taylor, G.4    Sherer, T.5    Greenamyre, J.6
  • 88
    • 33646539545 scopus 로고    scopus 로고
    • Parkinson's Disease Foundation, www.pdf.org; 2005.
    • (2005)
  • 89
    • 13144282676 scopus 로고    scopus 로고
    • Intraputamenal infusion of glial cell line-derived neurotrophic factor in PD: A two-year outcome study
    • Patel, N. K.; Bunnage, M.; Plaha, P.; Svendsen, C. N.; Heywood, P.; Gill, S. S. Intraputamenal infusion of glial cell line-derived neurotrophic factor in PD: A two-year outcome study. Ann. Neurol. 57(2):298-302; 2005.
    • (2005) Ann. Neurol. , vol.57 , Issue.2 , pp. 298-302
    • Patel, N.K.1    Bunnage, M.2    Plaha, P.3    Svendsen, C.N.4    Heywood, P.5    Gill, S.S.6
  • 90
    • 0023719445 scopus 로고
    • The adrenal medullary transplant operation for Parkinson's disease: Clinical observations in five patients
    • Penn, R. D.; Goetz, C. G.; Tanner, C. M.; Klawans, H. L.; Shannon, K. M.; Comella, C. L. The adrenal medullary transplant operation for Parkinson's disease: Clinical observations in five patients. Neurosurgery 22(6 Pt. 1):999-1004; 1988.
    • (1988) Neurosurgery , vol.22 , Issue.6 PART 1 , pp. 999-1004
    • Penn, R.D.1    Goetz, C.G.2    Tanner, C.M.3    Klawans, H.L.4    Shannon, K.M.5    Comella, C.L.6
  • 91
    • 0001418286 scopus 로고    scopus 로고
    • The MPTP-lesioned non-human primate: A model for Parkinson's disease
    • Marwah, J.; Teiltelbaum, H., eds. Scottsdale: Prominent Press
    • Petzinger, G.; Langston, J. The MPTP-lesioned non-human primate: A model for Parkinson's disease. In: Marwah, J.; Teiltelbaum, H., eds. Advances in neurodegenerative disorders: Parkinson's disease. Scottsdale: Prominent Press; 1998.
    • (1998) Advances in Neurodegenerative Disorders: Parkinson's Disease
    • Petzinger, G.1    Langston, J.2
  • 92
    • 0023778626 scopus 로고
    • The neurotoxin MPTP does not reproduce in the rhesus monkey the interregional pattern of striatal dopamine loss typical of human idieopathic Parkinson's disease
    • Pifl, C.; Schingnitz, G.; Hornykiewicz, O. The neurotoxin MPTP does not reproduce in the rhesus monkey the interregional pattern of striatal dopamine loss typical of human idieopathic Parkinson's disease. Neurosci. Lett. 92(2):228-233; 1988.
    • (1988) Neurosci. Lett. , vol.92 , Issue.2 , pp. 228-233
    • Pifl, C.1    Schingnitz, G.2    Hornykiewicz, O.3
  • 94
    • 0027452130 scopus 로고
    • Differential localization of A2a adenosine receptor mRNA with D1 and D2 dopamine receptor mRNA in striatal output pathways following a selective lesion of striatonigral neurons
    • Pollack, A. E.; Harrison, M. B.; Wooten, G. F.; Fink, J. S. Differential localization of A2a adenosine receptor mRNA with D1 and D2 dopamine receptor mRNA in striatal output pathways following a selective lesion of striatonigral neurons. Brain Res. 631(1):161-166; 1993.
    • (1993) Brain Res. , vol.631 , Issue.1 , pp. 161-166
    • Pollack, A.E.1    Harrison, M.B.2    Wooten, G.F.3    Fink, J.S.4
  • 95
    • 0029015394 scopus 로고
    • Dose-dependent lesions of the dopaminergic nigrostriatal pathway induced by intrastriatal injection of 6-hydroxydopamine
    • Przedborski, S.; Levivier, M.; Jiang, H.; Ferreira, M.; Jackson-Lewis, V.; Donaldson, D.; Togasaki, D. Dose-dependent lesions of the dopaminergic nigrostriatal pathway induced by intrastriatal injection of 6-hydroxydopamine. Neuroscience 67:631-647; 1995.
    • (1995) Neuroscience , vol.67 , pp. 631-647
    • Przedborski, S.1    Levivier, M.2    Jiang, H.3    Ferreira, M.4    Jackson-Lewis, V.5    Donaldson, D.6    Togasaki, D.7
  • 96
    • 0035091767 scopus 로고    scopus 로고
    • The parkinsonian toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): A technical review of its utility and safety
    • Przedborski, S.; Jackson-Lewis, V.; Naini, A. B.; Jakowec, M.; Petzinger, G.; Miller, R.; Akram, M. The parkinsonian toxin 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine (MPTP): A technical review of its utility and safety. J. Neurochem. 76(5):1265-1274; 2001.
    • (2001) J. Neurochem. , vol.76 , Issue.5 , pp. 1265-1274
    • Przedborski, S.1    Jackson-Lewis, V.2    Naini, A.B.3    Jakowec, M.4    Petzinger, G.5    Miller, R.6    Akram, M.7
  • 97
    • 27744450270 scopus 로고    scopus 로고
    • Alpha-synuclein expression in the substantia nigra of MPTP-lesioned non-human primates
    • Purisai, M. G.; McCormack, A. L.; Langsten, W. J.; Johnston, L. C.; DiMonte, D. A. Alpha-synuclein expression in the substantia nigra of MPTP-lesioned non-human primates. Neurobiol. Dis. 20(3):898-906; 2005.
    • (2005) Neurobiol. Dis. , vol.20 , Issue.3 , pp. 898-906
    • Purisai, M.G.1    McCormack, A.L.2    Langsten, W.J.3    Johnston, L.C.4    Dimonte, D.A.5
  • 98
    • 0002057279 scopus 로고
    • 6-Hydroxydopamine lesions of nigrostriatal neurons as an animal model of Parkinson's disease
    • Woodruf, M.; Nonneman, A., eds. New York: Plenum Press
    • Reading, P.; Dunnett, S. 6-Hydroxydopamine lesions of nigrostriatal neurons as an animal model of Parkinson's disease. In: Woodruf, M.; Nonneman, A., eds. Toxin-induced models of neuroglogical disorders. New York: Plenum Press; 1994.
    • (1994) Toxin-induced Models of Neuroglogical Disorders
    • Reading, P.1    Dunnett, S.2
  • 100
    • 27644459974 scopus 로고    scopus 로고
    • Paraquat neurotoxicity is distinct from that of MPTP and rotenone
    • Richardson, J.; Quan, Y.; Sherer, T.; Greenamyre, J.; Miller, G. Paraquat neurotoxicity is distinct from that of MPTP and rotenone. Toxicol. Sci. 88(1):193-201; 2005.
    • (2005) Toxicol. Sci. , vol.88 , Issue.1 , pp. 193-201
    • Richardson, J.1    Quan, Y.2    Sherer, T.3    Greenamyre, J.4    Miller, G.5
  • 102
    • 0016411549 scopus 로고
    • Mechanisms of action of 6-hydroxydopamine
    • Sachs, C.; Jonsson, G. Mechanisms of action of 6-hydroxydopamine. Biochem. Pharmacol. 24:1-8; 1975.
    • (1975) Biochem. Pharmacol. , vol.24 , pp. 1-8
    • Sachs, C.1    Jonsson, G.2
  • 103
    • 23044486663 scopus 로고    scopus 로고
    • Acute intranigral infusion of rotenone in rats causes progressive biochemical lesions in the striatum similar to Parkinson's disease
    • Saravanan, K. S.; Sindhu, K. M.; Mohanakumar, K. P. Acute intranigral infusion of rotenone in rats causes progressive biochemical lesions in the striatum similar to Parkinson's disease. Brain Res. 1049(2):147-155; 2005.
    • (2005) Brain Res. , vol.1049 , Issue.2 , pp. 147-155
    • Saravanan, K.S.1    Sindhu, K.M.2    Mohanakumar, K.P.3
  • 104
    • 0027330986 scopus 로고
    • Robust survival of isolated bovine adrenal chromaffinn cells following intrastriatal transplantation: A novel hypothesis of adrenal graft viability
    • Schueler, S. B.; Ortega, J. D.; Sagen, J.; Kordower, J. H. Robust survival of isolated bovine adrenal chromaffinn cells following intrastriatal transplantation: A novel hypothesis of adrenal graft viability. J. Neurosci. 13(10):4496-4510; 1993.
    • (1993) J. Neurosci. , vol.13 , Issue.10 , pp. 4496-4510
    • Schueler, S.B.1    Ortega, J.D.2    Sagen, J.3    Kordower, J.H.4
  • 105
    • 0023855541 scopus 로고
    • MPTP-induced parkinsonism in monkeys: Mechanism of action, selectivity and pathophysiology
    • Schultz, W. MPTP-induced parkinsonism in monkeys: Mechanism of action, selectivity and pathophysiology. Gen. Pharmacol. 19:153-161; 1988.
    • (1988) Gen. Pharmacol. , vol.19 , pp. 153-161
    • Schultz, W.1
  • 106
    • 0030175258 scopus 로고    scopus 로고
    • The unilateral 6-hydroxydopamine lesions of meso-striatal dopamine neurons and their physiological sequelae
    • Schwarting, R.; Huston, J. The unilateral 6-hydroxydopamine lesions of meso-striatal dopamine neurons and their physiological sequelae. Prog. Neurobiol. 49(3):215-266; 1996.
    • (1996) Prog. Neurobiol. , vol.49 , Issue.3 , pp. 215-266
    • Schwarting, R.1    Huston, J.2
  • 108
    • 0023993161 scopus 로고
    • Transplantation of fetal neurons in primates
    • Sladek, Jr., J. R.; Redmond, Jr., D. E.; Roth, R. H. Transplantation of fetal neurons in primates. Clin. Res. 36(3):200-204; 1988.
    • (1988) Clin. Res. , vol.36 , Issue.3 , pp. 200-204
    • Sladek Jr., J.R.1    Redmond Jr., D.E.2    Roth, R.H.3
  • 109
    • 0027291317 scopus 로고
    • Fetal dopamine cell survival after transplantation is dramatically improved at a critical donor gestational age in nonhuman primates
    • Sladek, Jr., J. R.; Elsworth, J. D.; Roth, R. H.; Evans, L. E.; Collier, T. J.; Cooper, S. J.; Taylor, J. R.; Redmond, Jr., D. E. Fetal dopamine cell survival after transplantation is dramatically improved at a critical donor gestational age in nonhuman primates. Exp. Neurol. 122(1):16-27; 1993.
    • (1993) Exp. Neurol. , vol.122 , Issue.1 , pp. 16-27
    • Sladek Jr., J.R.1    Elsworth, J.D.2    Roth, R.H.3    Evans, L.E.4    Collier, T.J.5    Cooper, S.J.6    Taylor, J.R.7    Redmond Jr., D.E.8
  • 110
    • 0031944244 scopus 로고    scopus 로고
    • Intrastriatal grafts from multiple donors do not result in a proportional increase in survival of dopamine neurons in non-human primates
    • Sladek, Jr., J. R.; Collier, T. J.; Elsworth, J. D.; Roth, R. H.; Taylor, J. R.; Redmond, Jr., D. E. Intrastriatal grafts from multiple donors do not result in a proportional increase in survival of dopamine neurons in non-human primates. Cell Transplant. 7(2):87-96; 1998.
    • (1998) Cell Transplant. , vol.7 , Issue.2 , pp. 87-96
    • Sladek Jr., J.R.1    Collier, T.J.2    Elsworth, J.D.3    Roth, R.H.4    Taylor, J.R.5    Redmond Jr., D.E.6
  • 111
    • 0017158756 scopus 로고
    • Transplantation of central and peripheral monoamine neurons to the adult rat brain: Techniques and conditions for survival
    • Stenevi, U.; Björklund, A.; Svendgaard, N. A. Transplantation of central and peripheral monoamine neurons to the adult rat brain: Techniques and conditions for survival. Brain Res. 114(1):1-20; 1976.
    • (1976) Brain Res. , vol.114 , Issue.1 , pp. 1-20
    • Stenevi, U.1    Björklund, A.2    Svendgaard, N.A.3
  • 112
    • 0031265935 scopus 로고    scopus 로고
    • Long-term survival of human central nervous system progenitor cells transplanted into a rat model of Parkinson's disease
    • Svendsen, C. N.; Caldwell, M. A.; Shen, J.; ter Borg, M. G.; Rosser, A. E.; Tyers, P.; Karmiol, S.; Dunnett, S. B. Long-term survival of human central nervous system progenitor cells transplanted into a rat model of Parkinson's disease. Exp. Neurol. 148(1):135-146; 1997.
    • (1997) Exp. Neurol. , vol.148 , Issue.1 , pp. 135-146
    • Svendsen, C.N.1    Caldwell, M.A.2    Shen, J.3    Ter Borg, M.G.4    Rosser, A.E.5    Tyers, P.6    Karmiol, S.7    Dunnett, S.B.8
  • 115
    • 0028859322 scopus 로고
    • Sham surgery does not ameliorate MPTP-induced behavioral deficits in monkeys
    • Taylor, J. R.; Schmieder, G. J.; Shimizu, T.; Tie, C.; Streilein, J. W. Sham surgery does not ameliorate MPTP-induced behavioral deficits in monkeys. Cell Transplant. 4(1):13-26; 1995.
    • (1995) Cell Transplant. , vol.4 , Issue.1 , pp. 13-26
    • Taylor, J.R.1    Schmieder, G.J.2    Shimizu, T.3    Tie, C.4    Streilein, J.W.5
  • 116
    • 0031587263 scopus 로고    scopus 로고
    • Severe long-term 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in the vervet monkey (Cercopithecus aethiops sabaeus)
    • Taylor, J.; Elsworth, J.; Roth, R.; Sladek, Jr., J.; Redmond, Jr., D. Severe long-term 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in the vervet monkey (Cercopithecus aethiops sabaeus). Neuroscience 81(3):745-755; 1997.
    • (1997) Neuroscience , vol.81 , Issue.3 , pp. 745-755
    • Taylor, J.1    Elsworth, J.2    Roth, R.3    Sladek Jr., J.4    Redmond Jr., D.5
  • 118
    • 0034637267 scopus 로고    scopus 로고
    • A. Potentiated and preferential effects of combined paraquat and maneb on nigrostriatal dopamine systems: Environmental risk factors for Parkinson's disease
    • Thiruchelvam, M.; Brockel, B. J.; Richfield, E. K.; Baggs, R. B.; Cory-Slechta, D. A. Potentiated and preferential effects of combined paraquat and maneb on nigrostriatal dopamine systems: Environmental risk factors for Parkinson's disease. Brain Res. 873(2):225-234; 2000.
    • (2000) Brain Res. , vol.873 , Issue.2 , pp. 225-234
    • Thiruchelvam, M.1    Brockel, B.J.2    Richfield, E.K.3    Baggs, R.B.4    Cory-Slechta, D.5
  • 119
    • 0014376793 scopus 로고
    • 6-Hydroxydopamine induced degeneration of central monoamine neurons
    • Ungerstedt, U. 6-Hydroxydopamine induced degeneration of central monoamine neurons. Eur. J. Pharmacol. 5:107-110; 1968.
    • (1968) Eur. J. Pharmacol. , vol.5 , pp. 107-110
    • Ungerstedt, U.1
  • 120
    • 5444255433 scopus 로고    scopus 로고
    • Neurotoxicant-induced animal models of Parkinson's disease; Understanding the role of rotenone, maneb and paraquat in neurodegeneration
    • Uversky, V. Neurotoxicant-induced animal models of Parkinson's disease; Understanding the role of rotenone, maneb and paraquat in neurodegeneration. Cell Tissue Res. 318(1):225-241; 2004.
    • (2004) Cell Tissue Res. , vol.318 , Issue.1 , pp. 225-241
    • Uversky, V.1
  • 121
    • 0028048579 scopus 로고
    • The primate subthalamic nucleus. I. Functional properties in intact animals
    • Wichmann, T.; Bergman, H.; DeLong, M. R. The primate subthalamic nucleus. I. Functional properties in intact animals. J. Neurophysiol. 72(2):494-506; 1994.
    • (1994) J. Neurophysiol. , vol.72 , Issue.2 , pp. 494-506
    • Wichmann, T.1    Bergman, H.2    Delong, M.R.3
  • 122
    • 28844448703 scopus 로고    scopus 로고
    • The bipyridyl herbicide paraquat produces oxidative stress-mediated toxicity in human neuroblastoma SH-SY5Y cells: Relevance to the dopaminergic pathogenesis
    • Yang, W.; Tiffany-Castiglioni, E. The bipyridyl herbicide paraquat produces oxidative stress-mediated toxicity in human neuroblastoma SH-SY5Y cells: Relevance to the dopaminergic pathogenesis. J. Toxicol. Environ. Health A 68(22):1939-1961; 2005.
    • (2005) J. Toxicol. Environ. Health A , vol.68 , Issue.22 , pp. 1939-1961
    • Yang, W.1    Tiffany-Castiglioni, E.2
  • 123
    • 0037265974 scopus 로고    scopus 로고
    • Manganese ethylene-bis-dithiocarbamate and selective dopaminergic neurodegeneration in rat: A link through mitochondrial dysfunction
    • Zhang, J.; Fitsanakis, V.; Gu, G.; Jing, D.; Ao, M.; Amarnath, V.; Montine, T. Manganese ethylene-bis-dithiocarbamate and selective dopaminergic neurodegeneration in rat: A link through mitochondrial dysfunction. J. Neurochem. 84(2):336-346; 2003.
    • (2003) J. Neurochem. , vol.84 , Issue.2 , pp. 336-346
    • Zhang, J.1    Fitsanakis, V.2    Gu, G.3    Jing, D.4    Ao, M.5    Amarnath, V.6    Montine, T.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.