Acute treatment with pentobarbital alters the kinetics of in vivo receptor binding in the mouse brain

Nuclear Medicine and Biology

Volumn 33, Issue 4, 2006, Pages 535-541

  Sakiyama, Yojiro ^a   Saito, Masao ^b   Inoue, Osamu ^c  

^a NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

Author keywords

Benzodiazepine; In vivo; Kinetics; Pentobarbital; Receptors; Ro 15 1788 (flumazenil)

Indexed keywords

BENZODIAZEPINE RECEPTOR; FLUMAZENIL; FLUMAZENIL 3 H; PENTOBARBITAL; TRACER; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING SITE; BRAIN CORTEX; CEREBELLUM; COMPARTMENT MODEL; CONTROLLED STUDY; DISSOCIATION CONSTANT; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; IN VIVO STUDY; KINETICS; MALE; MEDULLA OBLONGATA; MOUSE; NONHUMAN; PONS; RADIOACTIVITY; RECEPTOR BINDING;

ANIMALS; BRAIN; DOSE-RESPONSE RELATIONSHIP, DRUG; FLUMAZENIL; HYPNOTICS AND SEDATIVES; KINETICS; MALE; METABOLIC CLEARANCE RATE; MICE; MICE, INBRED STRAINS; PENTOBARBITAL; PROTEIN BINDING; RADIOISOTOPE DILUTION TECHNIQUE; RADIOPHARMACEUTICALS; RECEPTORS, GABA-A; TISSUE DISTRIBUTION; TRITIUM;

EID: 33646543684     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nucmedbio.2006.02.002     Document Type: Article

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