Sustained elevation of extracellular adenosine and activation of A 1 receptors underlie the post-ischaemic inhibition of neuronal function in rat hippocampus in vitro

Journal of Neurochemistry

Volumn 97, Issue 5, 2006, Pages 1357-1368

  Pearson, Tim ^a   Damian, Karen ^a   Lynas, Rachel E ^a   Frenguelli, Bruno G ^a,b  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

Adenosine; Epilepsy; Hypoxia; Ischaemia; Neuroprotection; Stroke

Indexed keywords

ADENOSINE; ADENOSINE A1 RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; BRAIN SLICE; CONTROLLED STUDY; EPILEPSY; EXCITATORY POSTSYNAPTIC POTENTIAL; FEMALE; HIPPOCAMPUS; MALE; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PURINE METABOLISM; RAT; RECEPTOR BLOCKING; STROKE;

ADENOSINE; ANIMALS; BRAIN ISCHEMIA; EXCITATORY AMINO ACID ANTAGONISTS; EXCITATORY POSTSYNAPTIC POTENTIALS; EXTRACELLULAR FLUID; FEMALE; HIPPOCAMPUS; MALE; NEURAL INHIBITION; NEURONS; ORGAN CULTURE TECHNIQUES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, ADENOSINE A1; RECEPTORS, N-METHYL-D-ASPARTATE; SYNAPTIC TRANSMISSION;

EID: 33646537781     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2006.03823.x     Document Type: Article

References (59)

1. Aden U Lindstrom K Bona E Hagberg H Fredholm BB 1994 Changes in adenosine receptors in the neonatal rat brain following hypoxic ischemia Brain ResMolBrain Res 23 354 358
2. Anderson WW Collingridge GL 2001 The LTP Program: a data acquisition program for on-line analysis of long-term potentiation and other synaptic events JNeurosciMeth 108 71 83
3. Arlinghaus L Lee KS 1996 Endogenous adenosine mediates the sustained inhibition of excitatory synaptic transmission during moderate hypoxia Brain Res 724 265 268
4. 1 receptors impairs the recovery of synaptic transmission after hypoxia Neuroscience 132 575 580
5. Brambilla D Chapman D Greene R 2005 Adenosine mediation of presynaptic feedback inhibition of glutamate release Neuron 46 275 283
6. Coelho JE de Mendonça A Ribeiro JA 2000 Presynaptic inhibitory receptors mediate the depression of synaptic transmission upon hypoxia in rat hippocampal slices Brain Res 869 158 165
7. Dale N 1998 Delayed production of adenosine underlies temporal modulation of swimming in frog embryo JPhysiol 511 265 272
8. Dale N Pearson T Frenguelli BG 2000 Direct measurement of adenosine release during hypoxia in the CA1 region of the rat hippocampal slice JPhysiol 526 143 155
9. Dale N Gourine AV Llaudet E Bulmer D Thomas T Spyer KM 2002 Rapid adenosine release in the nucleus tractus solitarii during defence response in rats: real-time measurement in vivo JPhysiol 544 149 160
10. DiGeronimo RJ Gegg CA Zuckerman SL 1998 Adenosine depletion alters postictal hypoxic cerebral vasodilation in the newborn pig AmJPhysiol 274 H1495 H1501
11. Dirnagl U Simon RP Hallenbeck JM 2003 Ischemic tolerance and endogenous neuroprotection Trends Neurosci 26 248 254
12. Dunwiddie TV Diao L 1994 Extracellular adenosine concentrations in hippocampal brain slices and the tonic inhibitory modulation of evoked excitatory responses JPharmacolExpTher 268 537 545
13. 1 receptor-mediated responses in rat hippocampus JNeurosci 17 607 614
14. During MJ Spencer DD 1992 Adenosine: a potential mediator of seizure arrest and postictal refractoriness AnnNeurol 32 618 624
15. Dux E Fastbom J Ungerstedt U Rudolphi K Fredholm BB 1990 Protective effect of adenosine and a novel xanthine derivative propentofylline on the cell damage after bilateral carotid occlusion in the gerbil hippocampus Brain Res 516 248 256
16. Etherington LA Frenguelli BG 2004 Endogenous adenosine modulates epileptiform activity in rat hippocampus in a receptor subtype-dependent manner EurJNeurosci 19 2539 2550
17. Fairchild MD Parsons JE Wasterlain CG Rinaldi PC Wallis RA 1988 A hypoxic injury potential in the hippocampal slice Brain Res 453 357 361
18. Ferguson G Watterson KR Palmer TM 2000 Subtype-specific kinetics of inhibitory adenosine receptor internalization are determined by sensitivity to phosphorylation by G protein-coupled receptor kinases MolPharmacol 57 546 552
19. Fowler JC 1989 Adenosine antagonists delay hypoxia-induced depressions of neuronal activity in hippocampal brain slice Brain Res 490 378 384
20. Fredholm BB Chen JF Cunha RA Svenningsson P Vaugeois JM 2005a Adenosine and brain function IntRevNeurobiol 63 191 270
21. Fredholm BB Chen JF Masino SA Vaugeois JM 2005b Actions of adenosine at its receptors in the CNS: insights from knockouts and drugs AnnuRevPharmacolToxicol 45 385 412
22. Frenguelli BG 1997 The effects of metabolic stress on glutamate receptor-mediated depolarisations in the in vitro rat hippocampal slice Neuropharmacology 36 981 991
23. Frenguelli BG Llaudet E Dale N 2003 High-resolution real-time recording with microelectrode biosensors reveals novel aspects of adenosine release during hypoxia in rat hippocampal slices JNeurochem 86 1506 1515
24. Gadalla AE Pearson T Currie AJ et al. 2004 AICA riboside both activates AMP-activated protein kinase and competes with adenosine for the nucleoside transporter in the CA1 region of the rat hippocampus JNeurochem 88 1272 1282
25. Gervitz LM Lutherer LO Davies DG Pirch JH Fowler JC 2001 Adenosine induces initial hypoxic-ischemic depression of synaptic transmission in the rat hippocampus in vivo AmJPhysiolRegulIntegrCompPhysiol 280 R639 R645
26. Gouder N Scheurer L Fritschy JM Boison D 2004 Overexpression of adenosine kinase in epileptic hippocampus contributes to epileptogenesis JNeurosci 24 692 701
27. 1 receptor desensitization after focal long-term delivery of adenosine by encapsulated myoblasts ExpNeurol 193 53 64
28. Hagberg H Anderson P Butcher S Sandberg M Lehmann A Hamberger A 1986 Blockade of N-methyl- d -aspartate-sensitive acidic amino acid receptors inhibits ischemia-induced accumulation of purine catabolites in the rat striatum NeurosciLett 68 311 316
29. + channels in cerebral ischemic preconditioning ProcNatl AcadSciUSA 92 4666 4670
30. 1 receptor ProcNatl AcadSciUSA 98 9407 9412
31. Kirino T 2002 Ischemic tolerance JCerebBlood Flow Metab 22 1283 1296
32. 1 receptor gene expression in cerebral ischemia of Wistar rats NeurosciLett 387 59 61
33. Latini S Pedata F 2001 Adenosine in the central nervous system: release mechanisms and extracellular concentrations JNeurochem 79 463 484
34. Latini S Bordoni F Pedata F Corradetti R 1999 Extracellular adenosine concentrations during in vitro ischaemia in rat hippocampal slices BrJPharmacol 127 729 739
35. Lee KS Tetzlaff W Kreutzberg GW 1986 Rapid down regulation of hippocampal adenosine receptors following brief anoxia Brain Res 380 155 158
36. 1 receptor inhibition Neuroscience 112 319 329
37. Lynch JJ Alexander KM Jarvis MF Kowaluk EA 1998 Inhibition of adenosine kinase during oxygen-glucose deprivation in rat cortical neuronal cultures NeurosciLett 252 207 210
38. de Mendonça A Ribeiro JA 1997 Contribution of metabotropic glutamate receptors to the depression of excitatory postsynaptic potentials during hypoxia Neuroreport 8 3667 3671
39. de Mendonça A Sebastiao AM Ribeiro JA 2000 Adenosine: does it have a neuroprotective role after all? Brain ResRev 33 258 274
40. 1 receptor binding in the post-ischaemic rat brain Neuroreport 5 1453 1456
41. Olah ME Stiles GL 2000 The role of receptor structure in determining adenosine receptor activity PharmacolTher 85 55 75
42. Opitz T Reymann KG 1993 (1S, 3R)-ACPD protects synaptic transmission from hypoxia in hippocampal slices Neuropharmacology 32 103 104
43. Pearson T Frenguelli BG 2000 Volume-regulated anion channels do not contribute extracellular adenosine during the hypoxic depression of excitatory synaptic transmission in area CA1 of rat hippocampus EurJNeurosci 12 3064 3066
44. Pearson T Frenguelli BG 2004 Adrenoceptor subtype-specific acceleration of the hypoxic depression of excitatory synaptic transmission in area CA1 of rat hippocampus EurJNeurosci 20 1555 1565
45. Pearson T Nuritova F Caldwell D Dale N Frenguelli BG 2001 A depletable pool of adenosine in area CA1 of the rat hippocampus JNeurosci 21 2298 2307
46. Pearson T Currie AJ Etherington LA Gadalla AE Damian K Llaudet E Dale N Frenguelli BG 2003 Plasticity of purine release during cerebral ischemia: clinical implications? JCellMolMed 7 362 375
47. Pedata F Latini S Pugliese AM Pepeu G 1993 Investigations into the adenosine outflow from hippocampal slices evoked by ischemia-like conditions JNeurochem 61 284 289
48. Phillis JW O'Regan MH 2003 In vivo studies of the release of adenine 5′-nucleotides, adenosine, and its metabolites from the rat brain Drug DevRes 58 412 419
49. ATP channels JCerebBlood Flow Metab 19 1296 1308
50. Rudolphi KA Schubert P Parkinson FE Fredholm BB 1992 Neuroprotective role of adenosine in cerebral ischaemia Trends PharmacSci 13 439 445
51. 1 receptor in adult mice using an adeno-associated viral vector JNeurosci 23 5762 5770
52. Sebastiao AM de Mendonça A Moreira T Ribeiro JA 2001 Activation of synaptic NMDA receptors by action potential-dependent release of transmitter during hypoxia impairs recovery of synaptic transmission on reoxygenation JNeurosci 21 8564 8571
53. Sick TJ Solow EL Roberts EL 1987 Extracellular potassium ion activity and electrophysiology in the hippocampal slice: paradoxical recovery of synaptic transmission during anoxia Brain Res 418 227 234
54. Stone TW 2002 Purines and neuroprotection AdvExpMedBiol 513 249 280
55. Valtysson J Persson L Hillered L 1998 Extracellular ischaemia markers in repeated global ischaemia and secondary hypoxaemia monitored by microdialysis in rat brain Acta Neurochir(Wien) 140 387 395
56. Wang T Raley-Susman KM Wang J Chambers G Cottrell JE Kass IS 1999 Thiopental attenuates hypoxic changes of electrophysiology, biochemistry, and morphology in rat hippocampal slice CA1 pyramidal cells Stroke 30 2400 2407
57. 1 adenosine receptors JNeurosci 22 1248 1255
58. Zhou AM Li WB Li QJ Liu HQ Feng RF Zhao HG 2004 A short cerebral ischemic preconditioning up-regulates adenosine receptors in the hippocampal CA1 region of rats NeurosciRes 48 397 404
59. Zhu PJ Krnjevic K 1999 Persistent block of CA1 synaptic function by prolonged hypoxia Neuroscience 90 759 770