-
1
-
-
0034715822
-
Association of the human papillomavirus type 11 E1()E4 protein with cornified cell envelopes derived from infected genital epithelium
-
Bryan J.T., and Brown D.R. Association of the human papillomavirus type 11 E1()E4 protein with cornified cell envelopes derived from infected genital epithelium. Virology 277 2 (2000) 262-269
-
(2000)
Virology
, vol.277
, Issue.2
, pp. 262-269
-
-
Bryan, J.T.1
Brown, D.R.2
-
2
-
-
0034653991
-
The human papillomavirus type 11 E1E4 protein is phosphorylated in genital epithelium
-
Bryan J.T., Han A., Fife K.H., and Brown D.R. The human papillomavirus type 11 E1E4 protein is phosphorylated in genital epithelium. Virology 268 2 (2000) 430-439
-
(2000)
Virology
, vol.268
, Issue.2
, pp. 430-439
-
-
Bryan, J.T.1
Han, A.2
Fife, K.H.3
Brown, D.R.4
-
3
-
-
0036305474
-
Distinct roles for cyclins E and A during DNA replication complex assembly and activation
-
Coverley D., Laman H., and Laskey R.A. Distinct roles for cyclins E and A during DNA replication complex assembly and activation. Nat. Cell Biol. 4 7 (2002) 523-528
-
(2002)
Nat. Cell Biol.
, vol.4
, Issue.7
, pp. 523-528
-
-
Coverley, D.1
Laman, H.2
Laskey, R.A.3
-
4
-
-
0025024373
-
Coexpression of the human papillomavirus type 16 E4 and L1 open reading frames in early cervical neoplasia
-
Crum C.P., Barber S., Symbula M., Snyder K., Saleh A.M., and Roche J.K. Coexpression of the human papillomavirus type 16 E4 and L1 open reading frames in early cervical neoplasia. Virology 178 (1990) 238-246
-
(1990)
Virology
, vol.178
, pp. 238-246
-
-
Crum, C.P.1
Barber, S.2
Symbula, M.3
Snyder, K.4
Saleh, A.M.5
Roche, J.K.6
-
5
-
-
0036776321
-
Identification of a G (2) arrest domain in the E1 wedge E4 protein of human papillomavirus type 16
-
Davy C.E., Jackson D.J., Wang Q., Raj K., Masterson P.J., Fenner N.F., Southern S., Cuthill S., Millar J.B., and Doorbar J. Identification of a G (2) arrest domain in the E1 wedge E4 protein of human papillomavirus type 16. J. Virol. 76 19 (2002) 9806-9818
-
(2002)
J. Virol.
, vol.76
, Issue.19
, pp. 9806-9818
-
-
Davy, C.E.1
Jackson, D.J.2
Wang, Q.3
Raj, K.4
Masterson, P.J.5
Fenner, N.F.6
Southern, S.7
Cuthill, S.8
Millar, J.B.9
Doorbar, J.10
-
6
-
-
20144380152
-
Human papillomavirus type 16 E1 E4-induced G2 arrest is associated with cytoplasmic retention of active Cdk1/cyclin B1 complexes
-
Davy C.E., Jackson D.J., Raj K., Peh W.L., Southern S.A., Das P., Sorathia R., Laskey P., Middleton K., Nakahara T., Wang Q., Masterson P.J., Lambert P.F., Cuthill S., Millar J.B., and Doorbar J. Human papillomavirus type 16 E1 E4-induced G2 arrest is associated with cytoplasmic retention of active Cdk1/cyclin B1 complexes. J. Virol. 79 7 (2005) 3998-4011
-
(2005)
J. Virol.
, vol.79
, Issue.7
, pp. 3998-4011
-
-
Davy, C.E.1
Jackson, D.J.2
Raj, K.3
Peh, W.L.4
Southern, S.A.5
Das, P.6
Sorathia, R.7
Laskey, P.8
Middleton, K.9
Nakahara, T.10
Wang, Q.11
Masterson, P.J.12
Lambert, P.F.13
Cuthill, S.14
Millar, J.B.15
Doorbar, J.16
-
7
-
-
10044284508
-
Cyclin/CDK regulates the nucleocytoplasmic localization of the human papillomavirus E1 DNA helicase
-
Deng W., Lin B.Y., Jin G., Wheeler C.G., Ma T., Harper J.W., Broker T.R., and Chow L.T. Cyclin/CDK regulates the nucleocytoplasmic localization of the human papillomavirus E1 DNA helicase. J. Virol. 78 24 (2004) 13954-13965
-
(2004)
J. Virol.
, vol.78
, Issue.24
, pp. 13954-13965
-
-
Deng, W.1
Lin, B.Y.2
Jin, G.3
Wheeler, C.G.4
Ma, T.5
Harper, J.W.6
Broker, T.R.7
Chow, L.T.8
-
8
-
-
0025148460
-
Detection of novel splicing patterns in a HPV 16-containing keratinocyte cell line
-
Doorbar J., Parton A., Hartley K., Banks L., Crook T., Stanley M., and Crawford L. Detection of novel splicing patterns in a HPV 16-containing keratinocyte cell line. Virology 178 (1990) 254-262
-
(1990)
Virology
, vol.178
, pp. 254-262
-
-
Doorbar, J.1
Parton, A.2
Hartley, K.3
Banks, L.4
Crook, T.5
Stanley, M.6
Crawford, L.7
-
9
-
-
0025819651
-
Specific interaction between HPV-16 E1-E4 and cytokeratins results in collapse of the epithelial cell intermediate filament network
-
Doorbar J., Ely S., Sterling J., McLean C., and Crawford L. Specific interaction between HPV-16 E1-E4 and cytokeratins results in collapse of the epithelial cell intermediate filament network. Nature 352 6338 (1991) 824-827
-
(1991)
Nature
, vol.352
, Issue.6338
, pp. 824-827
-
-
Doorbar, J.1
Ely, S.2
Sterling, J.3
McLean, C.4
Crawford, L.5
-
10
-
-
0026560424
-
Epitope-mapped monoclonal antibodies against the HPV16E1-E4 protein
-
Doorbar J., Ely S., Coleman N., Hibma M., Davies D.H., and Crawford L. Epitope-mapped monoclonal antibodies against the HPV16E1-E4 protein. Virology 187 1 (1992) 353-359
-
(1992)
Virology
, vol.187
, Issue.1
, pp. 353-359
-
-
Doorbar, J.1
Ely, S.2
Coleman, N.3
Hibma, M.4
Davies, D.H.5
Crawford, L.6
-
11
-
-
0031564066
-
Characterization of events during the late stages of HPV16 infection in vivo using high-affinity synthetic Fabs to E4
-
Doorbar J., Foo C., Coleman N., Medcalf L., Hartley O., Prospero T., Napthine S., Sterling J., Winter G., and Griffin H. Characterization of events during the late stages of HPV16 infection in vivo using high-affinity synthetic Fabs to E4. Virology 238 1 (1997) 40-52
-
(1997)
Virology
, vol.238
, Issue.1
, pp. 40-52
-
-
Doorbar, J.1
Foo, C.2
Coleman, N.3
Medcalf, L.4
Hartley, O.5
Prospero, T.6
Napthine, S.7
Sterling, J.8
Winter, G.9
Griffin, H.10
-
12
-
-
0033623193
-
The E1E4 protein of human papillomavirus type 16 associates with a putative RNA helicase through sequences in its C terminus
-
Doorbar J., Elston R.C., Napthine S., Raj K., Medcalf E., Jackson D., Coleman N., Griffin H.M., Masterson P., Stacey S., Mengistu Y., and Dunlop J. The E1E4 protein of human papillomavirus type 16 associates with a putative RNA helicase through sequences in its C terminus. J. Virol. 74 21 (2000) 10081-10095
-
(2000)
J. Virol.
, vol.74
, Issue.21
, pp. 10081-10095
-
-
Doorbar, J.1
Elston, R.C.2
Napthine, S.3
Raj, K.4
Medcalf, E.5
Jackson, D.6
Coleman, N.7
Griffin, H.M.8
Masterson, P.9
Stacey, S.10
Mengistu, Y.11
Dunlop, J.12
-
13
-
-
8844286090
-
Cyclin-dependent kinase inhibitor indirubin-3′-oxime selectively inhibits human papillomavirus type 16 E7-induced numerical centrosome anomalies
-
Duensing S., Duensing A., Lee D.C., Edwards K.M., Piboonniyom S.O., Manuel E., Skaltsounis L., Meijer L., and Munger K. Cyclin-dependent kinase inhibitor indirubin-3′-oxime selectively inhibits human papillomavirus type 16 E7-induced numerical centrosome anomalies. Oncogene 23 50 (2004) 8206-8215
-
(2004)
Oncogene
, vol.23
, Issue.50
, pp. 8206-8215
-
-
Duensing, S.1
Duensing, A.2
Lee, D.C.3
Edwards, K.M.4
Piboonniyom, S.O.5
Manuel, E.6
Skaltsounis, L.7
Meijer, L.8
Munger, K.9
-
14
-
-
0032728975
-
Human cyclin A is required for mitosis until mid prophase
-
Furuno N., den Elzen N., and Pines J. Human cyclin A is required for mitosis until mid prophase. J. Cell Biol. 147 2 (1999) 295-306
-
(1999)
J. Cell Biol.
, vol.147
, Issue.2
, pp. 295-306
-
-
Furuno, N.1
den Elzen, N.2
Pines, J.3
-
15
-
-
0026320075
-
Cyclin A is required for the onset of DNA replication in mammalian fibroblasts
-
Girard F., Strausfeld U., Fernandez A., and Lamb N.J. Cyclin A is required for the onset of DNA replication in mammalian fibroblasts. Cell 67 6 (1991) 1169-1179
-
(1991)
Cell
, vol.67
, Issue.6
, pp. 1169-1179
-
-
Girard, F.1
Strausfeld, U.2
Fernandez, A.3
Lamb, N.J.4
-
16
-
-
0024591788
-
Phosphorylation of the human papillomavirus type 1 E4 proteins in vivo and in vitro
-
Grand R.J., Doorbar J., Smith K.J., Coneron I., and Gallimore P.H. Phosphorylation of the human papillomavirus type 1 E4 proteins in vivo and in vitro. Virology 170 1 (1989) 201-213
-
(1989)
Virology
, vol.170
, Issue.1
, pp. 201-213
-
-
Grand, R.J.1
Doorbar, J.2
Smith, K.J.3
Coneron, I.4
Gallimore, P.H.5
-
17
-
-
0033166064
-
Translocation of cyclin B1 to the nucleus at prophase requires a phosphorylation-dependent nuclear import signal
-
Hagting A., Jackman M., Simpson K., and Pines J. Translocation of cyclin B1 to the nucleus at prophase requires a phosphorylation-dependent nuclear import signal. Curr. Biol. 9 13 (1999) 680-689
-
(1999)
Curr. Biol.
, vol.9
, Issue.13
, pp. 680-689
-
-
Hagting, A.1
Jackman, M.2
Simpson, K.3
Pines, J.4
-
18
-
-
0141856272
-
Direct activation of cyclin-dependent kinase 2 by human papillomavirus E7
-
He W., Staples D., Smith C., and Fisher C. Direct activation of cyclin-dependent kinase 2 by human papillomavirus E7. J. Virol. 77 19 (2003) 10566-10574
-
(2003)
J. Virol.
, vol.77
, Issue.19
, pp. 10566-10574
-
-
He, W.1
Staples, D.2
Smith, C.3
Fisher, C.4
-
19
-
-
0037034870
-
The subcellular localization of cyclin dependent kinase 2 determines the fate of mesangial cells: role in apoptosis and proliferation
-
Hiromura K., Pippin J.W., Blonski M.J., Roberts J.M., and Shankland S.J. The subcellular localization of cyclin dependent kinase 2 determines the fate of mesangial cells: role in apoptosis and proliferation. Oncogene 21 11 (2002) 1750-1758
-
(2002)
Oncogene
, vol.21
, Issue.11
, pp. 1750-1758
-
-
Hiromura, K.1
Pippin, J.W.2
Blonski, M.J.3
Roberts, J.M.4
Shankland, S.J.5
-
20
-
-
0001414735
-
Papillomaviruses and their replication
-
Fields B.N., Knipe D.M., and Howley P.M. (Eds), Lippincott Williams and Wilkins, Philadelphia, New York 2 vols
-
Howley P.M., and Lowy D.R. Papillomaviruses and their replication. In: Fields B.N., Knipe D.M., and Howley P.M. (Eds). Virology vol. 2 (2001), Lippincott Williams and Wilkins, Philadelphia, New York 2197-2229 2 vols
-
(2001)
Virology
, vol.2
, pp. 2197-2229
-
-
Howley, P.M.1
Lowy, D.R.2
-
21
-
-
0036201059
-
Cyclin A- and cyclin E-Cdk complexes shuttle between the nucleus and the cytoplasm
-
Jackman M., Kubota Y., den Elzen N., Hagting A., and Pines J. Cyclin A- and cyclin E-Cdk complexes shuttle between the nucleus and the cytoplasm. Mol. Biol. Cell 13 3 (2002) 1030-1045
-
(2002)
Mol. Biol. Cell
, vol.13
, Issue.3
, pp. 1030-1045
-
-
Jackman, M.1
Kubota, Y.2
den Elzen, N.3
Hagting, A.4
Pines, J.5
-
22
-
-
0028209073
-
Interaction of the E6 protein of human papillomavirus with cellular proteins
-
Keen N., Elston R., and Crawford L. Interaction of the E6 protein of human papillomavirus with cellular proteins. Oncogene 9 5 (1994) 1493-1499
-
(1994)
Oncogene
, vol.9
, Issue.5
, pp. 1493-1499
-
-
Keen, N.1
Elston, R.2
Crawford, L.3
-
23
-
-
10044250283
-
Cooperation between different forms of the human papillomavirus type 1 E4 protein to block cell cycle progression and cellular DNA synthesis
-
Knight G.L., Grainger J.R., Gallimore P.H., and Roberts S. Cooperation between different forms of the human papillomavirus type 1 E4 protein to block cell cycle progression and cellular DNA synthesis. J. Virol. 78 24 (2004) 13920-13933
-
(2004)
J. Virol.
, vol.78
, Issue.24
, pp. 13920-13933
-
-
Knight, G.L.1
Grainger, J.R.2
Gallimore, P.H.3
Roberts, S.4
-
24
-
-
0001450101
-
Papillomaviruses
-
Fields B.N., Knipe D.M., and Howley P.M. (Eds), Lippincott Williams and Wilkins, Philadelphia, New York 2 vols
-
Lowy D.R., and Howley P.M. Papillomaviruses. In: Fields B.N., Knipe D.M., and Howley P.M. (Eds). Virology vol. 2 (2001), Lippincott Williams and Wilkins, Philadelphia, New York 2231-2264 2 vols
-
(2001)
Virology
, vol.2
, pp. 2231-2264
-
-
Lowy, D.R.1
Howley, P.M.2
-
25
-
-
0033582278
-
Interaction between cyclin-dependent kinases and human papillomavirus replication-initiation protein E1 is required for efficient viral replication
-
Ma T., Zou N., Lin B.Y., Chow L.T., and Harper J.W. Interaction between cyclin-dependent kinases and human papillomavirus replication-initiation protein E1 is required for efficient viral replication. Proc. Natl. Acad. Sci. U. S. A. 96 2 (1999) 382-387
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, Issue.2
, pp. 382-387
-
-
Ma, T.1
Zou, N.2
Lin, B.Y.3
Chow, L.T.4
Harper, J.W.5
-
26
-
-
0141632854
-
Organization of human papillomavirus productive cycle during neoplastic progression provides a basis for selection of diagnostic markers
-
Middleton K., Peh W., Southern S., Griffin H., Sotlar K., Nakahara T., El-Sherif A., Morris L., Seth R., Hibma M., Jenkins D., Lambert P., Coleman N., and Doorbar J. Organization of human papillomavirus productive cycle during neoplastic progression provides a basis for selection of diagnostic markers. J. Virol. 77 19 (2003) 10186-10201
-
(2003)
J. Virol.
, vol.77
, Issue.19
, pp. 10186-10201
-
-
Middleton, K.1
Peh, W.2
Southern, S.3
Griffin, H.4
Sotlar, K.5
Nakahara, T.6
El-Sherif, A.7
Morris, L.8
Seth, R.9
Hibma, M.10
Jenkins, D.11
Lambert, P.12
Coleman, N.13
Doorbar, J.14
-
27
-
-
0036838212
-
Modulation of the cell division cycle by human papillomavirus type 18 E4
-
Nakahara T., Nishimura A., Tanaka M., Ueno T., Ishimoto A., and Sakai H. Modulation of the cell division cycle by human papillomavirus type 18 E4. J. Virol. 76 21 (2002) 10914-10920
-
(2002)
J. Virol.
, vol.76
, Issue.21
, pp. 10914-10920
-
-
Nakahara, T.1
Nishimura, A.2
Tanaka, M.3
Ueno, T.4
Ishimoto, A.5
Sakai, H.6
-
28
-
-
26444441402
-
Human papillomavirus type 16 E1{wedge}E4 contributes to multiple facets of the papillomavirus life cycle
-
Nakahara T., Peh W.L., Doorbar J., Lee D., and Lambert P.F. Human papillomavirus type 16 E1{wedge}E4 contributes to multiple facets of the papillomavirus life cycle. J. Virol. 79 20 (2005) 13150-13165
-
(2005)
J. Virol.
, vol.79
, Issue.20
, pp. 13150-13165
-
-
Nakahara, T.1
Peh, W.L.2
Doorbar, J.3
Lee, D.4
Lambert, P.F.5
-
29
-
-
0036784584
-
Life cycle heterogeneity in animal models of human papillomavirus-associated disease
-
Peh W.L., Middleton K., Christensen N., Nicholls P., Egawa K., Sotlar K., Brandsma J., Percival A., Lewis J., Liu W.J., and Doorbar J. Life cycle heterogeneity in animal models of human papillomavirus-associated disease. J. Virol. 76 20 (2002) 10401-10416
-
(2002)
J. Virol.
, vol.76
, Issue.20
, pp. 10401-10416
-
-
Peh, W.L.1
Middleton, K.2
Christensen, N.3
Nicholls, P.4
Egawa, K.5
Sotlar, K.6
Brandsma, J.7
Percival, A.8
Lewis, J.9
Liu, W.J.10
Doorbar, J.11
-
30
-
-
0842325980
-
The viral E4 protein is required for the completion of the cottontail rabbit papillomavirus productive cycle in vivo
-
Peh W.L., Brandsma J.L., Christensen N.D., Cladel N.M., Wu X., and Doorbar J. The viral E4 protein is required for the completion of the cottontail rabbit papillomavirus productive cycle in vivo. J. Virol. 78 4 (2004) 2142-2151
-
(2004)
J. Virol.
, vol.78
, Issue.4
, pp. 2142-2151
-
-
Peh, W.L.1
Brandsma, J.L.2
Christensen, N.D.3
Cladel, N.M.4
Wu, X.5
Doorbar, J.6
-
31
-
-
0026014878
-
Human cyclins A and B1 are differentially located in the cell and undergo cell cycle-dependent nuclear transport
-
Pines J., and Hunter T. Human cyclins A and B1 are differentially located in the cell and undergo cell cycle-dependent nuclear transport. J. Cell Biol. 115 1 (1991) 1-17
-
(1991)
J. Cell Biol.
, vol.115
, Issue.1
, pp. 1-17
-
-
Pines, J.1
Hunter, T.2
-
32
-
-
2942665475
-
E1 empty set E4 protein of human papillomavirus type 16 associates with mitochondria
-
Raj K., Berguerand S., Southern S., Doorbar J., and Beard P. E1 empty set E4 protein of human papillomavirus type 16 associates with mitochondria. J. Virol. 78 13 (2004) 7199-7207
-
(2004)
J. Virol.
, vol.78
, Issue.13
, pp. 7199-7207
-
-
Raj, K.1
Berguerand, S.2
Southern, S.3
Doorbar, J.4
Beard, P.5
-
33
-
-
0027152108
-
Localization of cyclin A at the sites of cellular DNA replication
-
Sobczak-Thepot J., Harper F., Florentin Y., Zindy F., Brechot C., and Puvion E. Localization of cyclin A at the sites of cellular DNA replication. Exp. Cell Res. 206 1 (1993) 43-48
-
(1993)
Exp. Cell Res.
, vol.206
, Issue.1
, pp. 43-48
-
-
Sobczak-Thepot, J.1
Harper, F.2
Florentin, Y.3
Zindy, F.4
Brechot, C.5
Puvion, E.6
-
34
-
-
0034090780
-
Evidence for keratinocyte immortalization in high-grade squamous intraepithelial lesions of the cervix infected with high-risk human papillomaviruses
-
Southern S.A., McDicken I.W., and Herrington C.S. Evidence for keratinocyte immortalization in high-grade squamous intraepithelial lesions of the cervix infected with high-risk human papillomaviruses. Lab. Invest. 80 4 (2000) 539-544
-
(2000)
Lab. Invest.
, vol.80
, Issue.4
, pp. 539-544
-
-
Southern, S.A.1
McDicken, I.W.2
Herrington, C.S.3
-
35
-
-
0032840918
-
Human papillomavirus is a necessary cause of invasive cervical cancer worldwide
-
Walboomers J., Jacobs M., Manos M.M., Bosch F., Kummer J., Shah K., Snijders P., Peto J., Meijer C., and Munoz N. Human papillomavirus is a necessary cause of invasive cervical cancer worldwide. J. Pathol. 189 1 (1999) 12-19
-
(1999)
J. Pathol.
, vol.189
, Issue.1
, pp. 12-19
-
-
Walboomers, J.1
Jacobs, M.2
Manos, M.M.3
Bosch, F.4
Kummer, J.5
Shah, K.6
Snijders, P.7
Peto, J.8
Meijer, C.9
Munoz, N.10
-
36
-
-
9144271383
-
Functional analysis of the human papillomavirus type 16 E1 (wedge)E4 protein provides a mechanism for in vivo and in vitro keratin filament reorganization
-
Wang Q., Griffin H., Southern S., Jackson D., Martin A., McIntosh P., Davy C., Masterson P.J., Walker P.A., Laskey P., Omary M.B., and Doorbar J. Functional analysis of the human papillomavirus type 16 E1 (wedge)E4 protein provides a mechanism for in vivo and in vitro keratin filament reorganization. J. Virol. 78 2 (2004) 821-833
-
(2004)
J. Virol.
, vol.78
, Issue.2
, pp. 821-833
-
-
Wang, Q.1
Griffin, H.2
Southern, S.3
Jackson, D.4
Martin, A.5
McIntosh, P.6
Davy, C.7
Masterson, P.J.8
Walker, P.A.9
Laskey, P.10
Omary, M.B.11
Doorbar, J.12
-
37
-
-
18744369062
-
Role of the E1-E4 protein in the differentiation-dependent life cycle of human papillomavirus type 31
-
Wilson R., Fehrmann F., and Laimins L.A. Role of the E1-E4 protein in the differentiation-dependent life cycle of human papillomavirus type 31. J. Virol. 79 11 (2005) 6732-6740
-
(2005)
J. Virol.
, vol.79
, Issue.11
, pp. 6732-6740
-
-
Wilson, R.1
Fehrmann, F.2
Laimins, L.A.3
-
38
-
-
0034235839
-
Early development of mouse embryos null mutant for the cyclin A2 gene occurs in the absence of maternally derived cyclin A2 gene products
-
Winston N., Bourgain-Guglielmetti F., Ciemerych M.A., Kubiak J.Z., Senamaud-Beaufort C., Carrington M., Brechot C., and Sobczak-Thepot J. Early development of mouse embryos null mutant for the cyclin A2 gene occurs in the absence of maternally derived cyclin A2 gene products. Dev. Biol. 223 1 (2000) 139-153
-
(2000)
Dev. Biol.
, vol.223
, Issue.1
, pp. 139-153
-
-
Winston, N.1
Bourgain-Guglielmetti, F.2
Ciemerych, M.A.3
Kubiak, J.Z.4
Senamaud-Beaufort, C.5
Carrington, M.6
Brechot, C.7
Sobczak-Thepot, J.8
-
39
-
-
0026605974
-
Cyclin A is required in S phase in normal epithelial cells
-
Zindy F., Lamas E., Chenivesse X., Sobczak J., Wang J., Fesquet D., Henglein B., and Brechot C. Cyclin A is required in S phase in normal epithelial cells. Biochem. Biophys. Res. Commun. 182 3 (1992) 1144-1154
-
(1992)
Biochem. Biophys. Res. Commun.
, vol.182
, Issue.3
, pp. 1144-1154
-
-
Zindy, F.1
Lamas, E.2
Chenivesse, X.3
Sobczak, J.4
Wang, J.5
Fesquet, D.6
Henglein, B.7
Brechot, C.8
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