Impairment of endothelium-dependent aorta relaxation by phospholipid components of oxidized low-density lipoprotein

Endothelium: Journal of Endothelial Cell Research

Volumn 13, Issue 1, 2006, Pages 1-8

  Vasques, Eunice ^a,b   Almeida, Andressa L F ^a   Noya, Vivian ^a   D'Alegria, Bárbara ^a   Marathe, Gopal ^c   McIntyre, Thomas M ^c   Tibiriçá, Eduardo ^a   Bozza, Patrícia T ^a   Silva, Adriana R ^a   Castro Faria Neto, Hugo C ^a  

^a INSTITUTO OSWALDO CRUZ   (Brazil)

^b FLUMINENSE FEDERAL UNIVERSITY   (Brazil)

^c LERNER RESEARCH INSTITUTE   (United States)

Author keywords

Aorta Relaxation; Atherosclerosis; Low Density Lipoprotein; Oxidized Phospholipids; PAF Mimetics

Indexed keywords

1 ALKYL 2 ACETYLGLYCEROPHOSPHOCHOLINE ESTERASE; ACETYLCHOLINE; NITROPRUSSIDE SODIUM; NORADRENALIN; OXIDIZED LOW DENSITY LIPOPROTEIN; PHOSPHOLIPID; THROMBOCYTE ACTIVATING FACTOR;

ANALYSIS OF VARIANCE; ANIMAL TISSUE; AORTA ATHEROSCLEROSIS; AORTA CONSTRICTION; ARTICLE; BLOOD VESSEL REACTIVITY; CONTROLLED STUDY; EVOKED RESPONSE; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; LIPID ANALYSIS; MALE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RABBIT; THORACIC AORTA; VASCULAR ENDOTHELIUM; VASCULAR RING; VASODILATATION;

1-ALKYL-2-ACETYLGLYCEROPHOSPHOCHOLINE ESTERASE; ACETYLCHOLINE; ANIMALS; AORTA; ATHEROSCLEROSIS; ENDOTHELIAL CELLS; FEMALE; HUMANS; LIPOPROTEINS, LDL; MALE; MUSCLE, SMOOTH, VASCULAR; NITROPRUSSIDE; NOREPINEPHRINE; ORGAN CULTURE TECHNIQUES; PHOSPHOLIPIDS; PLATELET ACTIVATING FACTOR; PLATELET MEMBRANE GLYCOPROTEINS; RABBITS; RECEPTORS, G-PROTEIN-COUPLED; VASOCONSTRICTOR AGENTS; VASODILATION; VASODILATOR AGENTS;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 33646506829     PISSN: 10623329     EISSN: 10292373     Source Type: Journal    
DOI: 10.1080/10623320600659948     Document Type: Article

References (48)

1. Aviram, M. (1989) Modified forms of low density lipoprotein affect platelet aggregation in vitro Thrombosis Research Supplement, 53, pp. 561-567. [CSA]
2. Bligh, E. and Dyer, W. (1959) A rapid method of total lipid extraction and purification Canadian Journal of Biochemical Physiology, 37, pp. 911-917. [CSA]
3. Bossaller, C. and Habib, G. and Yamamoto, H. and Williams, C. and Wells, S. and Henry, P. (1987b) Impaired muscarinic endothelium-dependent relaxation and cyclic guanosine 5′-monophosphate formation in atherosclerotic human coronary artery and rabbit aorta Journal of Clinical Investigation, 79, pp. 170-174. [INFOTRIEVE] [CSA]
4. Bossaller, C. and Reither, K. and Hehlert-Friedrich, C. and Auch-Schwelk, W. and Graf, K. and Grafe, M. and Fleck, E. (1992) In vivo measurement of endothelium-dependent vasodilation with substance P in man Herz, 17, pp. 284 - 290. [INFOTRIEVE] [CSA]
5. Bossaller, C. and Yamamoto, H. and Lichtlen, P. and Henry, P. (1987a) Impaired cholinergic vasodilation in the cholesterol-fed rabbit in vivo Basic Research in Cardiology, 82, pp. 396-404. [INFOTRIEVE] [CSA] [CROSSREF]
6. Bredt, D. and Snyder, S. (1992) Nitric oxide, a novel neuronal messenger Neuron, 8, pp. 3-11. [INFOTRIEVE] [CSA] [CROSSREF]
7. Brown, M. and Golstein, J. (1979) Receptors-mediated endocytosis: insights from the lipoprotein receptor system Proceedings National Academy of Sciences of the United States of America, 76, pp. 3330-3337. [CSA]
8. Busse, R. and Mulsch, A. (1990) Induction of nitric oxide synthase by cytokines in vascular smooth muscle cells FEBS Letters, 275, pp. 87-90. [INFOTRIEVE] [CSA] [CROSSREF]
9. Castro-Faria-Neto, H. and Stafforini, D. and Prescott, S. and Zimmerman, G. (2005) Regulating inflammation through the anti-inflammatory enzyme platelet-activating factor-acetylhydrolase Memórias do Instituto Oswaldo Cruz, 100, pp. 83-91. [CSA]
10. Chen, L. and Liang, B. and Froese, D. and Liu, S. and Wong, J. and Tran, K. and Hatch, G. and Mymin, D. and Kroeger, E. and Man, R. and Choy, P. (1997) Oxidative modification of low density lipoprotein in normal and hyperlipidemic patients: Effect of lysophosphatidylcholine composition on vascular relaxation Journal of Lipid Research, 38, pp. 546-553. [INFOTRIEVE] [CSA]
11. de Assis, E. and Silva, A. and Caiado, L. and Marathe, G. and Zimmerman, G. and Prescott, S. and McIntyre, T. and Bozza, P. and de Castro-Faria-Neto, H. (2003) Synergism between platelet-activating factor-like phospholipids and peroxisome proliferator-activated receptor gamma agonists generated during low density lipoprotein oxidation that induces lipid body formation in leukocytes Journal of Immunology, 171, pp. 2090 - 2098. [CSA]
12. Deckert, V. and Persegol, L. and Viens, L. and Lizard, G. and Athias, A. and Lallemant, C. and Gambert, P. and Lagrost, L. (1997) Inhibitors of arterial relaxation among components of human oxidized low-density lipoproteins. Cholesterol derivatives oxidized in position 7 are potent inhibitors of endothelium-dependent relaxation Circulation, 95, pp. 723-731. [INFOTRIEVE] [CSA]
13. Dentan, C. and Lesnik, P. and Chapman, M. and Ninio, E. (1994) PAF-acether-degrading acetylhydrolase in plasma LDL is inactivated by copper- and cell-mediated oxidation Arteriosclerosis Thrombosis and Vascular Biology, 14, pp. 353-360. [CSA]
14. Esterbauer, H. and Gebicki, J. and Puhl, H. and Jurgens, G. (1992) The role of lipid peroxidation and antioxidants in oxidative modification of LDL Free Radical Biology and Medicine, 13, pp. 341-390. [INFOTRIEVE] [CSA] [CROSSREF]
15. Goldstein, J. and Ho, Y. and Basu, S. and Brown, M. (1979) Binding site on macrophage that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition Proceedings National Academy of Sciences of the United States of America, 76, pp. 333-337. [CSA]
16. Gross, S. and Jaffe, E. and Levi, R. and Kilbourn, R. (1991) Cytokine-activated endothelial cells express an isotype of nitric oxide synthase which is tetrahydrobiopterin-dependent, calmodulin-independent and inhibited by arginine analogs with a rank-order of potency characteristic of activated macrophages Biochemical and Biophysical Research Communications, 178, pp. 823-829. [INFOTRIEVE] [CSA] [CROSSREF]
17. Heery, J. and Kozak, M. and Stafforini, D. and Jones, D. and Zimmerman, G. and McIntyre, T. and Prescott, S. (1995) Oxidatively modified LDL contains phospholipids with platelet-activating factor-like activity and stimulates the growth of smooth muscle cells Journal of Clinical Investigation, 96, pp. 2322-2330. [INFOTRIEVE] [CSA]
18. Heiber, M. and Docherty, J. and Shah, G. and Nguyen, T. and Cheng, R. and Heng, H. and Marchese, A. and Tsui, L. and Shi, X. and George, S. and (1995) Isolation of three novel human genes encoding G protein-coupled receptors DNA and Cell Biology, 14, pp. 25-35. [INFOTRIEVE] [CSA]
19. Hibbs, J., Jr and Taintor, R. and Vavrin, Z. and Rachlin, E. (1988) Nitric oxide: A cytotoxic activated macrophage effector molecule Biochemical and Biophysical Research Communications, 157, pp. 87-94. [INFOTRIEVE] [CSA] [CROSSREF]
20. Kabarowski, J. and Zhu, K. and Le, L. and Witte, O. and Xu, Y. (2001) Lysophosphatidylcholine as a ligand for the immunoregulatory receptor G2A Science, 293, pp. 702-705. [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
21. Kaluzny, M. and Duncan, L. and Merritt, M. and Epps, D. (1985) Rapid separation of lipid classes in high yield and purity using bonded phase columns Journal of Lipid Research, 26, pp. 135-140. [INFOTRIEVE] [CSA]
22. Kamido, H. and Eguchi, H. and Ikeda, H. and Imaizumi, T. and Yamana, K. and Hartvigsen, K. and Ravandi, A. and Kuksis, A. (2002) Core aldehydes of alkyl glycerophosphocholines in atheroma induce platelet aggregation and inhibit endothelium-dependent arterial relaxation Journal of Lipid Research, 43, pp. 158-166. [INFOTRIEVE] [CSA]
23. Kawashima, S. (2004) The two faces of endothelial nitric oxide synthase in the pathophysiology of atherosclerosis Endothelium, 11, pp. 99-107. [INFOTRIEVE] [CSA] [CROSSREF]
24. Kugiyama, K. and Kerns, S. and Morriset, J. and Roberts, R. and Henry, P. (1990) Impairment of endothelium-dependent arterial relaxation by lysolecithin in modified low-density lipoproteins Nature, 344, pp. 160-162. [INFOTRIEVE] [CSA] [CROSSREF]
25. Luoma, J. and Stralin, P. and Marklund, S. and Hiltunen, T. and Sarkioja, T. and Yla-Herttuala, S. (1998) Expression of extracellular SOD and iNOS in macrophages and smooth muscle cells in human and rabbit atherosclerosis lesions: Colocalization with epitopes characteristic of oxidized LDL and peroxinitrite-modified proteins Arteriosclerosis Thrombosis and Vascular Biology, 18, pp. 157-167. [CSA]
26. Marathe, G. and Davies, S. and Harrison, K. and Silva, A. and Murphy, R. and Castro-Faria-Neto, H. and Prescott, S. and Zimmerman, G. and McIntyre, T. (1999) Inflammatory PAF-like phospholipids in oxidized low density lipoprotein are fragmented alkyl phosphatidylcholines Journal of Biological Chemistry, 274, pp. 28395-28404. [INFOTRIEVE] [CSA] [CROSSREF]
27. Marathe, G. and Prescott, S. and Zimmerman, G. and McIntyre, T. (2001a) Oxidized LDL contains inflammatory PAF-like phospholipids Trends Cardiovascular Medicine, 11, pp. 139-142. [CSA] [CROSSREF]
28. Marathe, G. and Silva, A. and Castro-Faria-Neto, H. and Tjoelker, L. and Prescott, S. and Zimmerman, G. and McIntyre, T. (2001b) Lysophosphatidylcholine and lyso-PAF display PAF-like activity derived from contaminating phospholipids Journal of Lipid Research, 42, pp. 1430-1437. [INFOTRIEVE] [CSA]
29. 2+ signals and inhibit the phosphorylation of endothelial NO synthase and cytosolic phospholipase A2 Biochemical Journal, 380(Pt 2), pp. 533-539. [INFOTRIEVE] [CSA] [CROSSREF]
30. Murohara, T. and Kugiyama, K. and Ohgushi, M. and Sugiyama, S. and Ohta, Y. and Yasue, H. (1994) LPC in oxidized LDL elicits vasocontraction and inhibits endothelium-dependent relaxation American Journal of Physiology, 267(6 Pt 2), pp. H2441-H2449. [INFOTRIEVE] [CSA]
31. Ogita, H. and Liao, J. (2004) Endothelial function and oxidative stress Endothelium, 11, pp. 123-132. [INFOTRIEVE] [CSA] [CROSSREF]
32. Persegol, L. and Sementa, V. and Athias, A. and Lecerf, J. and Lallemant, C. and Gambert, P. (2000) Coincubation of native and oxidized low-density lipoproteins: Potentiation of relaxation impairment European Journal of Pharmacology, 406, pp. 429-437. [INFOTRIEVE] [CSA] [CROSSREF]
33. Plane, F. and Bruckdorfer, K. and Kerr, P. and Steuer, A. and Jacobs, M. (1992) Oxidative modification of low-density lipoprotein and the inhibition of relaxations mediated by endothelium-derived nitric oxide in rabbit aorta British Journal of Pharmacology, 105, pp. 216-222. [INFOTRIEVE] [CSA]
34. Radu, C. and Yang, L. and Riedinger, M. and Au, M. and Witte, O. (2004) T cell chemotaxis to lysophosphatidylcholine through the G2A receptor Proceedings National Academy of Sciences of the United States of America, 101, pp. 245-250. [CSA] [CROSSREF]
35. Rikitake, Y. and Hirata, K. and Kawashima, S. and Inoue, N. and Akita, H. and Kawai, Y. and Nakagawa, Y. and Yokoyama, M. (2000) Inhibition of endothelium-dependent arterial relaxation by oxidized phosphatidylcholine Atherosclerosis, 152, pp. 79-87. [INFOTRIEVE] [CSA] [CROSSREF]
36. Silva, A. and de Assis, E. and Caiado, L. and Marathe, G. and Bozza, M. and McIntyre, T. and Zimmerman, G. and Prescott, S. and Bozza, P. and Castro-Faria-Neto, H. (2002) MCP-1 and 5-lipoxigenase products recruit leukocytes in response to PAF-like lipids in oxidized LDL Journal of Immunology, 168, pp. 4112-4120. [CSA]
37. Stafforini, D. and Prescott, S. and McIntyre, T. (1987) Human plasma platelet-activating factor acetylhydrolase purification and properties Journal of Biological Chemistry, 262, pp. 4223-4230. [INFOTRIEVE] [CSA]
38. Steinberg, D. (1997) Low density lipoprotein oxidation and its pathobiological significance Journal of Biological Chemistry, 272, pp. 20963-20966. [INFOTRIEVE] [CSA] [CROSSREF]
39. Steinberg, D. and Lewis, A. (1997) Conner Memorial Lecture. Oxidative modification of LDL and atherogenesis Circulation, 95, pp. 1062-1071. [INFOTRIEVE] [CSA]
40. Steinbrecher, U. (1999) Receptors for oxidized low density lipoprotein Biochimica Biophysica Acta, 1436, pp. 279-298. [CSA]
41. Stremler, K. and Stafforini, D. and Prescott, S. and Zimmerman, G. and McIntyre, T. (1989) An oxidized derivative of phosphatidylcholine is a substrate for the platelet-activating factor acetylhydrolase from human plasma Journal of Biological Chemistry, 264, pp. 5331-5334. [INFOTRIEVE] [CSA]
42. Stuehr, D. and Griffith, O. (1992) Mammalian nitric oxide synthases Advances in Enzymology and Related Areas of Molecular Biology, 65, pp. 287-346. [INFOTRIEVE] [CSA]
43. Verbeuren, T. and Jordaens, F. and Van Hove, C. and Van Hoydonck, A. and Herman, A. (1990) Release and vascular activity of endothelium-derived relaxing factor in atherosclerotic rabbit aorta European Journal of Pharmacology, 191, pp. 173-184. [INFOTRIEVE] [CSA] [CROSSREF]
44. Watson, A. and Leitinger, N. and Navab, M. and Faull, K. and Horkko, S. and Witztum, J. and Palinski, W. and Schwenke, D. and Salomon, R. and Sha, W. and Subbanagounder, G. and Fogelman, A. and Berliner, J. (1997) Structural identification by mass spectrometry of oxidized phospholipids in minimally oxidized low density lipoprotein that induce monocyte/ endothelial interactions and evidence for their presence in vivo Journal of Biological Chemistry, 272, pp. 3597-13607. [CSA]
45. Weng, Z. and Fluckiger, A. and Nisitani, S. and Wahl, M. and Le, L. and Hunter, C. and Fernal, A. and Le Beau, M. and Witte, O. (1998) A DNA damage and stress inducible G protein-coupled receptor blocks cells in G2/M Proceedings National Academy of Sciences of the United States of America, 95, pp. 12334-12339. [CSA] [CROSSREF]
46. Witztum, J. and Steinberg, D. (1991) Role of oxidized low density lipoprotein in atherogenesis Journal of Clinical Investigation, 88, pp. 1785-1792. [INFOTRIEVE] [CSA]
47. Yang, L. and Radu, C. and Wang, L. and Riedinger, M. and Witte, O. (2005) Gi-independent macrophage chemotaxis to lysophosphatidylcholine via the immunoregulatory GPCR G2A Blood, 105, pp. 1127-1134. [INFOTRIEVE] [CSA] [CROSSREF]
48. Zhu, K. and Baudhuin, L. and Hong, G. and Williams, F. and Cristina, K. and Kabarowski, J. and Witte, O. and Xu, Y. (2001) Sphingosylphosphorylcholine and lysophosphatidylcholine are ligands for the G protein-coupled receptor GPR4 Journal of Biological Chemistry, 276, pp. 41325-41335. [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]