Oxidized LDL contains inflammatory PAF-like phospholipids

Trends in Cardiovascular Medicine

Volumn 11, Issue 3-4, 2001, Pages 139-142

  Marathe, Gopal K ^a   Prescott, Stephen M ^a   Zimmerman, Guy A ^a   McIntyre, Thomas M ^a,b  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF UTAH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; CIGARETTE SMOKE; FATTY ACID ESTER; HYDROLASE; LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; OXIDIZED LOW DENSITY LIPOPROTEIN; PHOSPHOLIPID; POLYUNSATURATED FATTY ACID; THROMBOCYTE ACTIVATING FACTOR; THROMBOCYTE ACTIVATING FACTOR RECEPTOR;

ATHEROGENESIS; ATHEROSCLEROSIS; BLOOD; CELL ACTIVATION; CELL METABOLISM; CHEMICAL STRUCTURE; DIET; DISEASE ASSOCIATION; ENDOTHELIUM CELL; ENDOTHELIUM LESION; ENZYME INACTIVATION; HUMAN; INFLAMMATORY CELL; LEUKOCYTE; LIPID METABOLISM; LIPID OXIDATION; LIPOGENESIS; MACROPHAGE ACTIVATION; MONOCYTE; NONHUMAN; OXIDATION; PHOSPHOLIPID MEMBRANE; PRIORITY JOURNAL; REVIEW; SMOOTH MUSCLE FIBER; THROMBOCYTE;

ANIMALS; HUMANS; INFLAMMATION MEDIATORS; LIPOPROTEINS, LDL; OXIDATION-REDUCTION; PHOSPHOLIPIDS; PLATELET ACTIVATING FACTOR;

EID: 0035181804     PISSN: 10501738     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1050-1738(01)00100-1     Document Type: Review

References (25)

1. Increase in fragmented phosphatidylcholine in blood plasma by oxidative stress
2. Absence of monocyte chemoattractant protein-1 reduces atherosclerosis in low-density lipoprotein receptor deficient mice
3. Oxidatively modified LDL contains phospholipids with PAF-like activity and stimulates the growth of smooth muscle cells
4. A mutation in plasma platelet-activating factor acetylhydrolase (Val 279Phe) is a genetic risk factor for stroke
5. Activation of the acetyl-coenzyme A: Lysoplatelet-activating factor acetyltransferase regulates platelet-activating factor synthesis in human endothelial cells
6. Effect of cigarette smoking on the levels of platelet-activating factor-like lipid(s) in plasma lipoproteins
7. Platelet-activating factor (PAF) receptor and genetically engineered PAF receptor mutant mice
8. Impaired anaphylactic responses but intact sensitivity to endotoxin in mice lacking a platelet-activating receptor
9. Vitamin C blocks inflammatory PAF mimetics created by cigarette smoking
10. Inflammatory platelet-activating factor-like phospholipids in oxidized low-density lipoproteins are fragmented alkyl phosphatidylcholines
11. Protection against oxidative stress-induced cell death by intracellular platelet activating factor-acetylhydrolase II
12. Platelet-activating factor mediates acid-induced lung injury in genetically engineered mice
13. Platelet-activating factor and related lipid mediators
14. Platelet-activating factor
15. Platelet-activating factor acetylhydrolase
16. Lipoproteins alter the catalytic behavior of the platelet-activating factor acetylhydrolase in human plasma
17. Platelet-activating factor acetylhydrolase deficiency. A missence mutation near the active site of an anti-inflammatory phospholipase
18. Human plasma platelet-activating factor acetylhydrolase: Oxidatively-fragmented phospholipids as substrates
19. Anti-inflammatory properties of platelet-activating factor acetylhydrolase
20. Structural identification by mass spectrometry of oxidized phospholipids in minimally oxidized low density lipoprotein that induce monocyte/endothelial interactions and evidence for their presence in vivo
21. Monocyte tethering by P-selectin regulates monocyte chemotactic protein-1 and tumor necrosis factor-alpha secretion
22. Correlations between plasma platelet-activating factor acetylhydrolase (PAF-AH) activity and PAF-AH genotype, age and atherosclerosis in a Japanese population
23. Juxtacrine intercellular signaling: Another way to do it
24. Endothelial cell interactions with granulocytes: Tethering and signaling molecules
25. Oxidatively fragmented phospholipids as inflammatory mediators: The dark side of polyunsaturated lipids