Respiratory dysfunction and proinflammatory chemokines in the pneumonia virus of mice (PVM) model of viral bronchiolitis

Virology

Volumn 349, Issue 1, 2006, Pages 87-95

  Bonville, Cynthia A ^a   Bennett, Nicholas J ^a   Koehnlein, Melissa ^b   Haines, Deborah M ^b   Ellis, John A ^b   DelVecchio, Alfred M ^c   Rosenberg, Helene F ^d   Domachowske, Joseph B ^a  

^a SUNY UPSTATE MEDICAL UNIVERSITY   (United States)

^b UNIVERSITY OF SASKATCHEWAN   (Canada)

^c CENTOCOR INC   (United States)

^d NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

Bronchiolitis; Chemokine; Inflammation; Pneumovirus

Indexed keywords

CHEMOKINE; GAMMA INTERFERON; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 5; MACROPHAGE INFLAMMATORY PROTEIN 1; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 2;

ACUTE DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRONCHUS MUCOSA; CLINICAL FEATURE; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; EXPERIMENTAL MODEL; EXPERIMENTAL MOUSE; INOCULATION; LUNG PARENCHYMA; MEDIATOR RELEASE; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PNEUMONIA; PNEUMOVIRINAE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RESPIRATORY FAILURE; SURVIVAL; SYMPTOM; TISSUE DISTRIBUTION; VIRAL BRONCHIOLITIS; VIRUS INACTIVATION; VIRUS REPLICATION;

ANIMALS; BRONCHIOLITIS, VIRAL; CHEMOKINE CCL2; CHEMOKINES; DISEASE MODELS, ANIMAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; INTERFERON TYPE II; LUNG; MACROPHAGE INFLAMMATORY PROTEIN-1; MICE; MICE, INBRED C57BL; MURINE PNEUMONIA VIRUS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PLETHYSMOGRAPHY, WHOLE BODY; PNEUMOVIRUS INFECTIONS; RESPIRATORY MECHANICS; RESPIRATORY MUCOSA; RNA, MESSENGER;

ANIMALIA; MURINE PNEUMONIA VIRUS; PNEUMOVIRINAE; PNEUMOVIRUS; POTATO VIRUS M; RODENTIA;

EID: 33646502819     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2006.02.017     Document Type: Article

References (45)

1. Blanco J.C., Richardson J.Y., Darnell M.E., Rowzee M.E., Pletneva L., Porter D.D., and Prince G.A. Cytokine and chemokine gene expression after primary and secondary respiratory syncytial virus infection in cotton rats. J. Infect. Dis. 185 (2002) 1780-1785
2. Bonville C.A., Easton A.J., Rosenberg H.F., and Domachowske J.B. Altered pathogenesis of severe pneumovirus infection in response to combined antiviral and specific immunomodulatory agents. J. Virol. 77 (2003) 1237-1244
3. Bonville C.A., Lau V.K., DeLeon J.M., Gao J.L., Easton A.J., Rosenberg H.F., and Domachowske J.B. Functional antagonism of chemokine receptor CCR1 reduces mortality in acute pneumovirus infection in vivo. J. Virol. 78 (2004) 7984-7989
4. Cai X., and Castleman W.L. Increased IFN-gamma protein in bronchoalveolar lavage fluid of anti-IP-10 antibody-treated F344 rats following Sendai viral infection. J. Interferon Cytokine Res. 22 (2002) 1175-1179
5. Cai X., and Castleman W.L. Early high expression of IL-10 in F344 rats resistant to Sendai virus-induced airway injury. Am. J. Physiol.: Lung Cell. Mol. Physiol. 285 (2003) L1263-L1269
6. Chavez-Bueno S., Mejias A., Gomez A.M., Olsen K.D., Rios A.M., Fonseca-Aten M., Ramilo O., and Jafri H.S. RSV-induced acute and chronic airway disease is independent of genetic background: an experimental murine model. J. Virol. 2 (2005) 46
7. Collins P.L., Chanock R.M., and Murphy B.R. Respiratory syncytial virus. In: Knipe D.M., and Howley P.M. (Eds). Fields Virology. 4th ed. vol. 1 (2001), Lippincott-Raven Publishers, Philadelphia 1443-1486
8. Cook P.M., Eglin R.P., and Easton A.J. Pathogenesis of pneumovirus infections in mice: detection of pneumonia virus of mice and human respiratory syncytial virus mRNA in lungs of infected mice by in situ hybridization. J. Gen. Virol. 79 (1998) 2411-2417
9. Domachowske J.B., Bonville C.A., Gao J.L., Murphy P.M., Easton A.J., and Rosenberg H.F. The chemokine macrophage-inflammatory protein-1 alpha and its receptor CCR1 control pulmonary inflammation and antiviral host defense in paramyxovirus infection. J. Immunol. 165 (2000) 2677-2682
10. Domachowske J.B., Bonville C.A., Ali-Ahmad D., Dyer K.D., Easton A.J., and Rosenberg H.F. Glucocorticoid administration accelerates mortality of pneumovirus-infected mice. J. Infect. Dis. 184 (2001) 1518-1523
11. Domachowske J.B., Bonville C.A., Easton A.J., and Rosenberg H.F. Differential expression of proinflammatory cytokine genes in vivo in response to pathogenic and nonpathogenic pneumovirus infections. J. Infect. Dis. 186 (2002) 8-14
12. Domachowske J.B., Bonville C.A., and Rosenberg H.F. Animal models for studying respiratory syncytial virus infection and its long term effects on lung function. Pediatr. Infect. Dis. J. 23 (2004) S228-S234
13. Durbin J.E., Johnson T.R., Durbin R.K., Mertz S.E., Morotti R.A., Peebles R.S., and Graham B.S. The role of IFN in respiratory syncytial virus pathogenesis. J. Immunol. 168 (2002) 2944-2952
14. Garofalo R.P., Patti J., Hintz K.A., Hill V., Ogra P.L., and Welliver R.C. Macrophage inflammatory protein-1 alpha (not T helper type 2 cytokines) is associated with severe forms of respiratory syncytial virus bronchiolitis. J. Infect. Dis. 184 (2001) 393-399
15. Haeberle H.A., Kuziel W.A., Dieterich H.J., Casola A., Gatalica Z., and Garofalo R.P. Inducible expression of inflammatory chemokines in respiratory syncytial virus-infected mice: role of MIP-1α in lung pathology. J. Virol. 75 (2001) 878-890
16. Haines D.M., and Chelack B.J. Technical considerations for developing immunohistochemical staining procedures on formalin-fixed paraffin-embedded tissues for diagnostic pathology. J. Vet. Diag. Invest. 3 (1991) 101-112
17. Harrison A.M., Bonville C.A., Rosenberg H.F., and Domachowske J.B. Respiratory syncytical virus-induced chemokine expression in the lower airways: eosinophil recruitment and degranulation. Am. J. Respir. Crit. Care Med. 159 (1999) 1918-1924
18. Hou S., and Doherty P.C. Clearance of Sendai virus by CD8+ T cells requires direct targeting to virus-infected epithelium. Eur. J. Immunol. 25 (1995) 111-116
19. Hou S., Hyland L., Ryan K.W., Portner A., and Doherty P.C. Virus-specific CD8+ T-cell memory determined by clonal burst size. Nature 369 (1994) 652-654
20. Hyland L., Hou S., Coleclough C., Takimoto T., and Doherty P.C. Mice lacking CD8+ T cells develop greater numbers of IgA-producing cells in response to a respiratory virus infection. Virology 204 (1994) 234-241
21. Ikemura T., Schwarze J., Makela M., Kanehiro A., Joetham A., Ohmori K., and Gelfand E.W. Type 4 phosphodiesterase inhibitors attenuate respiratory syncytial virus-induced airway hyperresponsiveness and lung eosinophilia. Pharmacol. Exper. Ther. 294 (2000) 701-706
22. Jafri H.S., Chavez-Bueno S., Mejias A., Gomez A.M., Rios A.M., Nassi S.S., Yusuf M., Kapur P., Hardy R.D., Hatfield J., Rogers B.B., Krisher K., and Ramilo O. Respiratory syncytial virus induces pneumonia, cytokine response, airway obstruction, and chronic inflammatory infiltrates associated with long-term airway hyperresponsiveness in mice. J. Infect. Dis. 189 (2004) 1856-1865
23. Mehta H., Sorkness R., Kaplan M.R., Castleman W.L., and Lemanske Jr. R.F. Effects of dexamethasone on acute virus-induced airway dysfunction in adult rats. Pediatr. Res. 41 (1997) 872-877
24. Mejias A., Chavez-Bueno S., Rios A.M., Saavedra-Lozano J., Fonseca-Aten M., Hatfield J., Kapur P., Gomez A.M., Jafri H.S., and Ramilo O. Anti-RSV neutralizing antibody decreases lung inflammation, airway obstruction and airway hyperresponsiveness in a murine RSV model. AAC 48 (2004) 1811-1822
25. Miller A.L., Bowlin T.L., and Lukacs N.W. Respiratory syncytial virus-induced chemokine production: linking viral replication to chemokine production in vitro and in vivo. J. Infect. Dis. 189 (2004) 1419-1430
26. Mo X.Y., Sarawar S.R., and Doherty P.C. Induction of cytokines in mice with parainfluenza pneumonia. J. Virol. 69 (1995) 1288-1291
27. Mo X.Y., Sangster M., Sarawar S., Coleclough C., and Doherty P.C. Differential antigen burden modulates the gamma interferon but not the immunoglobulin response in mice that vary in susceptibility to Sendai virus pneumonia. J. Virol. 69 (1995) 5592-5598
28. Noah T.L., and Becker S. Chemokines in nasal secretions of normal adults experimentally infected with respiratory syncytial virus. Clin. Immunol. 97 (2000) 43-49
29. Oh J.W., Lee H.B., Park I.K., and Kang J.O. Interleukin-6, interleukin-8, interleukin-11, and interferon-gamma levels in nasopharyngeal aspirates from wheezing children with respiratory syncytial virus or influenza A virus infection. Pediatr. Allergy Immunol. 13 (2002) 350-356
30. Rosenberg H.F., Bonville C.A., Easton A.J., and Domachowske J.B. The pneumonia virus of mice infection model for severe respiratory syncytial virus infection: identifying novel targets for therapeutic intervention. Pharmacol. Ther. 105 (2005) 1-6
31. Rosenthal L.A., Mikus L.D., Tuffaha A., Mosser A.G., Sorkness R.L., and Lemanske Jr. R.F. Attenuated innate mechanisms of interferon-gamma production in rats susceptible to postviral airway dysfunction. Am. J. Respir. Cell Mol. Biol. 30 (2004) 702-709
32. Schwarze J., and Schauer U. Enhanced virulence, airway inflammation and impaired lung function induced by RSV deficient in secreted G protein. Thorax 59 (2004) 517-521
33. Schwarze J., Cieslewicz G., Hamelmann E., Joetham A., Shultze A., Lamers M.C., and Gelfand E.W. IL-5 and eosinophils are essential for the development of airway hyperresponsiveness following acute RSV infection. J. Immunol. 162 (1999) 2997-3004
34. Schwarze J., Makela M., Cieslewicz G., Dakhama A., Lahn M., Ikemura T., Joetham A., and Gelfand E.W. Transfer of the enhancing effect of RSV infection on subsequent allergic airway sensitization by T lymphocytes. J. Immunol. 163 (1999) 5729-5734
35. Smyth R.L., Mobbs K.J., O'Hea U., Ashby D., and Hart C.A. Respiratory syncytial virus bronchiolitis: disease severity, interleukin-8, and virus genotype. Pediatr. Pulmonol. 33 (2002) 339-346
36. Sorkness R., Lemanske Jr. R.F., and Castleman W.L. Persistent airway hyperresponsiveness after neonatal viral bronchiolitis in rats. J. Appl. Physiol. 70 (1991) 375-383
37. Sorkness R.L., Castleman W.L., Mikus L.D., Mosser A.G., and Lemanske Jr. R.F. Chronic postbronchiolitis airway instability induced with anti-IFN-gamma antibody in F344 rats. Pediatr. Res. 52 (2002) 382-386
38. Sorkness R.L., Gern J.E., Grindle K.A., Mosser A.G., Rosenthal L.A., Mikus L.D., and Lemanske Jr. R.F. Persistance of viral RNA in two rat strains differing in susceptibility to postbronchiolitis airway dysfunction. J. Allergy Clin. Immunol. 110 (2002) 607-609
39. Stokes J.R., Sorkness R.L., Kaplan M.R., Castleman W.L., Tomai M.A., Miller R.L., and Lemanske Jr. R.F. Attenuation of virus-induced airway dysfunction in rats treated with imiquimod. Eur. Respir. J. 11 (1998) 324-329
40. Stone A.E., Giguere S., and Castleman W.L. IL-12 reduces the severity of Sendai virus-induced bronchiolar inflammation and remodeling. Cytokine 24 (2003) 103-113
41. Topham D.J., and Doherty P.C. Longitudinal analysis of the acute Sendai virus-specific CD4+ T cell response and memory. J. Immunol. 161 (1998) 4530-4535
42. Tripp R.A., Dakhama A., Jones L.P., Barskey A., Gelfand E.W., and Anderson L.J. The G glycoprotein of respiratory syncytial virus depresses respiratory rates through the CX3C motif and substance P. J. Virol. 77 (2003) 6580-6584
43. van Schaik S.M., Obot M., Einhorning G., Hintz K., Gross K., Hancock G.E., Stack A.M., and Welliver R.C. Role of interferon gamma in the pathogenesis of primary respiratory syncytial virus infection in BALB/c mice. J. Med. Virol. 62 (2000) 257-266
44. Welliver R.C., Garofalo R.P., and Ogra P.L. Beta-chemokines, but neither T helper type 1 nor T helper type 2 cytokines, correlate with severity of illness during respiratory syncytial virus infection. Pediatr. Infect. Dis. J. 21 (2002) 457-461
45. Zhang Y., Luxon B.A., Casola A., Garofalo R.P., Jamaluddin M., and Brasier A.R. Expression of respiratory syncytial virus-induced chemokine gene networks in lower airway epithelial cells revealed by cDNA microarrays. J. Virol. 75 (2001) 9044-9058