IL-12 reduces the severity of Sendai virus-induced bronchiolar inflammation and remodeling

Cytokine

Volumn 24, Issue 3, 2003, Pages 103-113

  Stone, Amy E S ^a   Giguere, Steeve ^a   Castleman, William L ^a  

^a Department of Oral Biology ^*

Author keywords

Fibrosis; IL 12; Inflammation; Lung; Virus

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 12; MESSENGER RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DENDRITIC CELL; DISEASE SEVERITY; GENE EXPRESSION; INFLAMMATION; MACROPHAGE; MALE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SENDAI VIRUS; SMALL AIRWAY DISEASE; TISSUE REGENERATION;

SENDAI VIRUS;

EID: 0242289412     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cyto.2003.07.005     Document Type: Article

References (34)

1. Stern A.S., Magram J., Presky D.H. Interleukin-12 an integral cytokine in the immune response. Life Sci. 58:1996;639-654.
2. Park A.Y., Scott P. IL-12: keeping cell-mediated immunity alive. Scand J Immunol. 53:2001;529-532.
3. Bette M., Jin S.C., Schafer M.K.H., Weihe E., Rude E., Fleischer B. Differential expression of mRNA encoding interleukin-12 p35 and p40 subunits in situ. Eur J Immunol. 15:1994;2435-2440.
4. Romani L., Puccetti P., Bistoni F. Interleukin-12 in infectious diseases. Clin Microbiol Rev. 10:1997;611-636.
5. Biron C.A., Orange J.S. IL-12 in acute viral infectious disease. Res Immunol. 146:(7-8):1995;590-597.
6. Tekkanat K.K., Maassab H., Berlin A.A., Lincoln P.M., Evanoff H.L., Kaplan M.H., et al. Role of interleukin-12 and stat-4 in the regulation of bronchiolar inflammation and hyperreactivity in respiratory syncytial virus infection. Am J Pathol. 159:2001;631-638.
7. Kanangat S., Thomas J., Gangappa S., Babu J.S., Rouse B.T. Herpes simplex virus type 1-mediated up-regulation of IL-12 (p40) mRNA expression. J Immunol. 156:1996;1110-1116.
8. Kumar A., Sorkness R.L., Kaplan M.R., Lemanske R.F. Chronic, episodic, reversible bronchiolar obstruction after viral bronchiolitis in rats. Am J Respir Crit Care Med. 155:1997;130-134.
9. Sorkness R.L., Castleman W.L., Kumar A., Kaplan M.R., Lemanske R.F. Prevention of chronic after bronchiolitis bronchiolar sequelae with IFN-γ treatment in rats. Am J Respir Crit Care Med. 160:1999;705-710.
10. Castleman W.L., Busse W.W., Sorden S.D., Dukes K.R. Hyperresponsiveness of BN rats to virus induced persistent lung dysfunction is associated with delayed viral clearance, high IL-4 and IL-5, and low CD8 cell and gamma-interferon response. Am J Respir Crit Care Med. 153:1996;A866.
11. Castleman W.L., Sorkness R.L., Lemanske R.F., McAllister P.K. Viral bronchiolitis during early like induces increased numbers of bronchiolar mast cells and bronchiolar hyperresponsiveness. Am J Pathol. 137:1990;821-831.
12. Uhl E.W., Castleman W.L., Sorkness R.L., Busse W.W., Lemanske R.F., McAllister P.K. Parainfluenza virus-induced persistence of bronchiolar inflammation, fibrosis, and dysfunction associated with TGF-β1 expression in Brown Norway rats. Am J Respir Crit Care Med. 154:1996;1834-1842.
13. Uhl E.W., Moldawer L.L., Busse W.W., Jack T.J., Castleman W.L. Increased tumor necrosis factor-α (TNF-α) in parainfluenza type 1 (Sendai) virus-induced bronchiolar fibrosis. Am J Pathol. 152:1998;513-522.
14. Sigurs N., Bjarnason R., Sigurbergsson F., Kjellman B., Bjorksten B. Asthma and immunoglobulin E antibodies after respiratory syncytial virus bronchiolitis: a prospective cohort study with matched controls. Pediatrics. 95:1995;500-505.
15. Sly P.D., Hibbert M.E. Childhood asthma following hospitalization with acute viral bronchiolitis in infancy. Pediatr Pulmonol. 7:1989;153-158.
16. Castleman W.L., Owens S.B., Brundage-Anguish L.J. Acute and persistent alterations in pulmonary inflammatory cells and bronchiolar mast cells induced by Sendai virus infection in neonatal rats. Vet Pathol. 26:1989;18-25.
17. Smith T., Hewson A.K., Kingsley C.I., Leonard J.P., Cuzner M.L. Interleukin-12 induces relapse in experimental allergic encephalomyelitis in the Lewis rat. Am J Pathol. 150:1997;1909-1917.
18. Gracie J.A., Bradley J. Interleukin-12 induces interferon-gamma- dependent switching of IgG alloantibody subclass. Eur J Immunol. 26:1996;1217-1221.
19. Mathieson P.W., Gillespie K.M. Cloning of a partial cDNA for rat interleukin-12 (IL-12) and analysis of expression in vitro. Scand J Immunol. 44:1996;11-14.
20. Barnes P.J. Cytokine modulators as novel therapies for asthma. Annu Rev Pharmacol Toxicol. 42:2002;81-98.
21. Puissant C., Hondebine L.M. An improvement of the single-step method of RNA isolation by acid guanidium thiocyanate-phenol chloroform extraction. Biotechniques. 8:1990;148-149.
22. ® polymerase chain reaction. J Vet Immunol Immunopathol. 77:2000;275-287.
23. Seigling A., Lehmann M., Platzer F., Emmrich, Volk H.D. A novel multispecific competitor fragment for quantitative PCR analysis of cytokine gene expression in rats. J Immunol Methods. 177:1994;23-28.
24. Kitchin K.T., Willard A.L., Suematsu. An ELISA assay for heme oxygenase (HO-1). J Immunol Methods. 247:2001;153-161.
25. Heinzel F.P., Hujer A.M., Ahmed F.N., Rerko R.M. In vivo production and function of IL-12 p40 homodimers. J Immunol. 158:1997;4381-4388.
26. Walter M.J., Kajiwara N., Karanja P., Castro M., Holtzman M.J. Interleukin 12 p40 production by barrier epithelial cells during bronchiolar inflammation. J Exp Med. 193:2001;339-351.
27. Arizono N., Koreto O., Nakao S., Iwai Y., Kushima R., Takeoka O. Phenotypic changes in mast cells proliferating in the rat lung following infection with Nipafterrongylus brasiliensis. Virchows Arch B. 54:1987;1-7.
28. Cai X., Castleman W.L. Differential IP-10 gene expression detected by suppressive subtractive hybridization in F344 rats resistant to viral airway injury. Am J Respir Crit Care Med. 163:2001;A198.
29. Fierer J., Walls L., Eckmann L., Yamamoto T., Kirkland T.N. Importance of interleukin-10 in genetic susceptibility of mice to Coccidioides immitis. Infect Immun. 66:1998;4397-4402.
30. Antunúez M.I., Cardoni R.L. IL-12 and IFN-γ production and NK cell activity, in acute and chronic experimental Trypanosoma cruzi infections. Immunol Lett. 71:2000;103-109.
31. Liu T., Nishimura H., Matsuguchi T., Yoshikai Y. Differences in interleukin-12 and -15 production by dendritic cells at the early stage of Listeria monocytogenes infection between BALB/c and C57BL/6 mice. Cell Immunol. 202:2000;31-40.
32. Trinchieri G. Interleukin-12: a cytokine at the interface of inflammation and immunity. Adv Immunol. 70:1998;83-243.
33. Keane M.P., Belperio J.A., Burdick M.D., Strieter R.M. Interleukin-12 attenuates pulmonary fibrosis via induction of Interferon-γ Chest. 120:2001;8S.
34. Gurujeyalakshmi G., Giri S. Molecular mechanisms of antifibrotic effect of interferon gamma in bleomycin-mouse model of lung fibrosis: down regulation of TGF-beta and procollagen I and III gene expression. Exp Lung Res. 21:1995;791-808.