A yeast assay probes the interaction between botulin neurotoxin serotype B and its SNARE substrate

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 18, 2006, Pages 6958-6963

  Fang, Hong ^a   Luo, Wentian ^a   Henkel, Jim ^b   Barbieri, Joseph ^b   Green, Neil ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

Endopeptidase; Endoprotease; Substrate specificity; Synaptic vesicle

Indexed keywords

BINDING PROTEIN; BOTULINUM TOXIN B; PROTEIN SNC2P; PROTEINASE; SNARE PROTEIN; SYNAPTOBREVIN; UNCLASSIFIED DRUG; ZINC;

ARTICLE; CHIMERA; CONTROLLED STUDY; DISULFIDE BOND; ENZYME ACTIVITY; FLACCID PARALYSIS; INTOXICATION; INTRACELLULAR MEMBRANE; LIGHT CHAIN; MEMBRANE FUSION; MONITORING; MOTONEURON; NONHUMAN; PRESYNAPTIC MEMBRANE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; RECEPTOR BINDING; SEROTYPE; SYNAPSE VESICLE; TECHNOLOGY; YEAST;

AMINO ACID SEQUENCE; ANIMALS; BIOLOGICAL ASSAY; BOTULINUM TOXINS; CELL MEMBRANE; CELL-FREE SYSTEM; CYTOPLASMIC VESICLES; HUMANS; MICE; MOLECULAR SEQUENCE DATA; MUTATION; NEURONS; RECOMBINANT FUSION PROTEINS; SACCHAROMYCES CEREVISIAE; SEQUENCE ALIGNMENT; SNARE PROTEINS;

EID: 33646476127     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0510816103     Document Type: Article

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