Substrate residues N-terminal to the cleavage site of botulinum type B neurotoxin play a role in determining the specificity of its endopeptidase activity

FEBS Letters

Volumn 386, Issue 2-3, 1996, Pages 133-136

  Wictome, Matthew ^a   Rossetto, Ornella ^b   Montecucco, Cesare ^b   Shone, Clifford C ^a  

^a PUBLIC HEALTH ENGLAND   (United Kingdom)

^b UNIVERSITY OF PADOVA   (Italy)

Author keywords

Botulinum; Neurotoxin; Peptide substrate; Synaptobrevin; VAMP; Zinc endopeptidase

Indexed keywords

BOTULINUM TOXIN B;

ARTICLE; BINDING SITE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME BINDING; ENZYME SPECIFICITY; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

EID: 0029891288     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-5793(96)00431-0     Document Type: Article

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