Copper(II)-mediated cross-coupling of arylboronic acids and 2(1H)-pyrazinones facilitated by microwave irradiation with simultaneous cooling

Organic Letters

Volumn 8, Issue 9, 2006, Pages 1863-1866

  Singh, Brajendra Kumar ^a,b   Appukkuttan, Prasad ^a   Claerhout, Stijn ^a   Parmar, Virinder Singh ^b   Van Der Eycken, Erik ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b UNIVERSITY OF DELHI   (India)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 33646450914     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol060422z     Document Type: Article

References (24)

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20. Experiments were carried out in an open and cooled vial applying a dedicated CEM-Discover-Coolmate monomode microwave apparatus operating at a frequency of 2.45 GHz with continuous irradiation power from 0 to 300 W (CEM Corporation, P.O. Box 200, Matthews, NC 28106).
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23. 2 (2 mL) were added all reagents as to perform the arylation according to the procedure described in footnote 14. This mixture was brought to 50 °C by conventional heating or microwave irradiation and checked by TLC after 5 and 60 min; partial decomposition of 3a was noticed.
24. 2 (1:1)] to furnish the products 3a-f,i,j.