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Volumn 8, Issue 9, 2006, Pages 1875-1878

Isonitrile trapping reactions under thermolysis of alkoxyamines for the synthesis of quinolines

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EID: 33646449642     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol0604421     Document Type: Article
Times cited : (81)

References (43)
  • 1
    • 0004269715 scopus 로고    scopus 로고
    • Renaud, P., Sibi, M. P., Eds.; Wiley-VCH: Weinheim, Germany
    • For reviews on radical chemistry, see: (a) Renaud, P., Sibi, M. P., Eds.; Radicals in Organic Synthesis; Wiley-VCH: Weinheim, Germany, 2001; Vois. 1 and 2.
    • (2001) Radicals in Organic Synthesis , vol.1-2
  • 4
    • 0002002167 scopus 로고    scopus 로고
    • Renaud, P., Sibi, M. P., Eds.; Wiley-VCH: Weinheim, Germany
    • Nanni, D. In Radicals in Organic Synthesis; Renaud, P., Sibi, M. P., Eds.; Wiley-VCH: Weinheim, Germany, 2001; Vol. 2, p 44.
    • (2001) Radicals in Organic Synthesis , vol.2 , pp. 44
    • Nanni, D.1
  • 33
    • 0035781101 scopus 로고    scopus 로고
    • (d) Review: Fischer, H. Chem. Rev. 2001, 101, 3581.
    • (2001) Chem. Rev. , vol.101 , pp. 3581
    • Fischer, H.1
  • 34
    • 33646441542 scopus 로고    scopus 로고
    • note
    • We thank a referee for this suggestion.
  • 36
    • 33646462395 scopus 로고    scopus 로고
    • note
    • The microwave experiments were conducted using professional laboratory microwave equipment. A MLS-Ethos 1600 Mikrowellen System (Milestone) was used for the present studies. The reactions were run in 40 mL MLS-reaction high-pressure vessels (up to 15 bar) which contain pressure-control valves. An advanced temperature control system from MLS allowing direct contactless temperature monitoring was used. The microwave power is continuously and dynamically adjusted to follow the defined temperature profile. Temperature profile for the quinoline synthesis: from 25 to 100 °C in 10 s; from 100 to 150 °C in 10 s; from 150 to 180 °C in 10 s and then keep the temperature at 180 °C for 30 min.
  • 41
    • 33646459269 scopus 로고    scopus 로고
    • note
    • As compared to the alkene-terminated alkoxyamines, compound 13 turned out to be thermally less stable for unknown reasons. This may lead to the lower yields observed.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.