Microwave assisted free radical cyclisation of alkenyl and alkynyl isocyanides with thiols

Tetrahedron Letters

Volumn 44, Issue 7, 2003, Pages 1347-1349

  Lamberto, Massimiliano ^a   Corbett, David F ^b   Kilburn, Jeremy D ^a  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CYANIDE; FREE RADICAL; MERCAPTOETHANOL; PYROGLUTAMIC ACID; PYRROLINE DERIVATIVE; THIOL DERIVATIVE; THIOPHENOL;

ARTICLE; COMBINATORIAL CHEMISTRY; CYCLIZATION; HEATING; INTERMETHOD COMPARISON; MICROWAVE RADIATION; SYNTHESIS;

EID: 0037429019     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(02)02888-5     Document Type: Article

References (10)

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2. Lew A., Krutzik P.O., Hart M.E., Chamberlin A.R. J. Comb. Chem. 4:2002;95-105.
3. Olofsson K., Kim S.-Y., Larhed M., Curran D.P., Hallberg A. J. Org. Chem. 64:1999;4539-4541.
4. Bachi M.D., Balanov A., Bar-Ner N. J. Org. Chem. 59:1994;7752-7758.
5. Bachi M.D., Lasanow D.G. Synlett. 1990;551-553.
6. Kotha S., Sreenivasachary N., Brahmachary E. Tetrahedron Lett. 39:1998;2805-2808.
7. Schollkopf U., Hoppe D., Jentsch R. Chem. Ber. 108:1975;1580-1592.
8. Wade H., Scanlan T.S. J. Am. Chem. Soc. 121:1999;1434-1443.
9. All microwave reactions were performed using the Smith Synthesiser™.
10. AIBN: N,N′-azobisisobutyronitrile; ACN: N,N′-cyclohexylcarbonitrile.