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Volumn 88, Issue 5, 2006, Pages 1053-1065

Up-regulation of bone morphogenetic proteins in cultured murine bone cells with use of specific electric fields

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 4; BONE MORPHOGENETIC PROTEIN 5; BONE MORPHOGENETIC PROTEIN 6; GREMLIN; NOGGIN; OSTEOGENIC PROTEIN 1; OSTEOGENIN; UNCLASSIFIED DRUG;

EID: 33646443845     PISSN: 00219355     EISSN: None     Source Type: Journal    
DOI: 10.2106/JBJS.E.00443     Document Type: Article
Times cited : (76)

References (60)
  • 1
    • 0001406145 scopus 로고
    • On the piezoelectric effect of bone
    • Fukuda E, Yasuda I. On the piezoelectric effect of bone. J Physiol Soc Jpn. 1957;12:1158-62.
    • (1957) J Physiol Soc Jpn , vol.12 , pp. 1158-1162
    • Fukuda, E.1    Yasuda, I.2
  • 2
    • 0002022932 scopus 로고
    • Electrical effects in bone
    • Bassett CA. Electrical effects in bone. Sei Am. 1965;213:18-25.
    • (1965) Sei Am , vol.213 , pp. 18-25
    • Bassett, C.A.1
  • 5
    • 1442329152 scopus 로고    scopus 로고
    • Treatment of nonunions with electric and electromagnetic fields
    • Aaron RK, Ciombor DM, Simon BJ. Treatment of nonunions with electric and electromagnetic fields. Clin Orthop Relat Res. 2004;419:21-9.
    • (2004) Clin Orthop Relat Res , vol.419 , pp. 21-29
    • Aaron, R.K.1    Ciombor, D.M.2    Simon, B.J.3
  • 7
    • 0026038907 scopus 로고
    • Enhancement of fracture healing by specific pulsed capacitively-coupled electric field stimulation
    • Chang WH, Hwang IM, Liu HC. Enhancement of fracture healing by specific pulsed capacitively-coupled electric field stimulation. Front Med Biol Eng. 1991;3:57-64.
    • (1991) Front Med Biol Eng , vol.3 , pp. 57-64
    • Chang, W.H.1    Hwang, I.M.2    Liu, H.C.3
  • 8
    • 0034252660 scopus 로고    scopus 로고
    • Pulsed electromagnetic fields promote bone formation around dental implants inserted into the femur of rabbits
    • Matsumoto H, Ochi M, Abiko Y, Hirose Y, Kaku T, Sakaguchi K. Pulsed electromagnetic fields promote bone formation around dental implants inserted into the femur of rabbits. Clin Oral Implants Res. 2000;11:354-60.
    • (2000) Clin Oral Implants Res , vol.11 , pp. 354-360
    • Matsumoto, H.1    Ochi, M.2    Abiko, Y.3    Hirose, Y.4    Kaku, T.5    Sakaguchi, K.6
  • 9
    • 0035515857 scopus 로고    scopus 로고
    • Enhancing osseointegration by capacitively coupled electric field: A pilot study on early occlusal loading in the dog mandible
    • Shigino T, Ochi M, Hirose Y, Hirayama H, Sakaguchi K. Enhancing osseointegration by capacitively coupled electric field: a pilot study on early occlusal loading in the dog mandible, lnt J Oral Maxillofac Implants. 2001;16:841-50.
    • (2001) Lnt J Oral Maxillofac Implants , vol.16 , pp. 841-850
    • Shigino, T.1    Ochi, M.2    Hirose, Y.3    Hirayama, H.4    Sakaguchi, K.5
  • 10
    • 0021888164 scopus 로고
    • Treatment of recalcitrant non-union with a capacitively coupled electrical field. A preliminary report
    • Brighton CT, Pollack SR. Treatment of recalcitrant non-union with a capacitively coupled electrical field. A preliminary report. J Bone Joint Surg Am. 1985;67:577-85.
    • (1985) J Bone Joint Surg Am , vol.67 , pp. 577-585
    • Brighton, C.T.1    Pollack, S.R.2
  • 11
    • 0033912666 scopus 로고    scopus 로고
    • Electrical stimulation in lumbar spinal fusion
    • Bush JL, Vaccaro AR. Electrical stimulation in lumbar spinal fusion. Orthopedics. 2000;23:737-45.
    • (2000) Orthopedics , vol.23 , pp. 737-745
    • Bush, J.L.1    Vaccaro, A.R.2
  • 12
    • 0033169020 scopus 로고    scopus 로고
    • A doubleblind study of capacitively coupled electrical stimulation as an adjunct to lumbar spinal fusions
    • Goodwin CB, Brighton CT, Guyer RD, Johnson JR, Light KI, Yuan HA. A doubleblind study of capacitively coupled electrical stimulation as an adjunct to lumbar spinal fusions. Spine. 1999;24:1349-57.
    • (1999) Spine , vol.24 , pp. 1349-1357
    • Goodwin, C.B.1    Brighton, C.T.2    Guyer, R.D.3    Johnson, J.R.4    Light, K.I.5    Yuan, H.A.6
  • 13
    • 0029737070 scopus 로고    scopus 로고
    • Bone morphogenetic proteins: Multifunctional regulators of vertebrate development
    • Hogan BL. Bone morphogenetic proteins: multifunctional regulators of vertebrate development. Genes Dev. 1996;10;1580-94.
    • (1996) Genes Dev , vol.10 , pp. 1580-1594
    • Hogan, B.L.1
  • 14
    • 13444291335 scopus 로고    scopus 로고
    • BMP signaling in skeletal development
    • Wan M, Cao X. BMP signaling in skeletal development. Biochem Biophys Res Commun. 2005;328:651-7,
    • (2005) Biochem Biophys Res Commun , vol.328 , pp. 651-657
    • Wan, M.1    Cao, X.2
  • 15
    • 0031733871 scopus 로고    scopus 로고
    • Expression of bone morphogenetic proteins in fracture healing
    • Bostrom MR Expression of bone morphogenetic proteins in fracture healing. Clin Orthop Relat Res. 1998;355 Suppl:S116-23.
    • (1998) Clin Orthop Relat Res , vol.355 , Issue.SUPPL.
    • Bostrom, M.R.1
  • 16
    • 0036181393 scopus 로고    scopus 로고
    • Differential temporal expression of members of the transforming growth factor beta superfamily during murine fracture healing
    • Cho TJ, Gerstenfeld LC, Einhorn TA. Differential temporal expression of members of the transforming growth factor beta superfamily during murine fracture healing. J Bone Miner Res. 2002;17:513-20.
    • (2002) J Bone Miner Res , vol.17 , pp. 513-520
    • Cho, T.J.1    Gerstenfeld, L.C.2    Einhorn, T.A.3
  • 17
    • 0034128748 scopus 로고    scopus 로고
    • The family of bone morphogenetic proteins
    • Ducy P, Karsenty G. The family of bone morphogenetic proteins. Kidney Int. 2000;57:2207-14.
    • (2000) Kidney Int , vol.57 , pp. 2207-2214
    • Ducy, P.1    Karsenty, G.2
  • 18
    • 0034777917 scopus 로고    scopus 로고
    • BMP signaling pathways in cartilage and bone formation
    • Hoffmann A, Gross G. BMP signaling pathways in cartilage and bone formation. Crit Rev Eukaryot Gene Expr. 2001;11:23-45.
    • (2001) Crit Rev Eukaryot Gene Expr , vol.11 , pp. 23-45
    • Hoffmann, A.1    Gross, G.2
  • 19
    • 0002071012 scopus 로고    scopus 로고
    • Bone morphogenetic proteins; from basic science to clinical applications
    • Reddi AH. Bone morphogenetic proteins; from basic science to clinical applications. J Bone Joint Surg Am. 2001;83 Suppl 1:S1-6.
    • (2001) J Bone Joint Surg Am , vol.83 , Issue.SUPPL. 1
    • Reddi, A.H.1
  • 20
    • 0031608330 scopus 로고    scopus 로고
    • The bone morphogenetic protein family: Multifunctional cellular regulators in the embryo and adult
    • Wozney JM. The bone morphogenetic protein family: multifunctional cellular regulators in the embryo and adult. Eur J Oral Sci. 1998;106 Suppl 1:160-6.
    • (1998) Eur J Oral Sci , vol.106 , Issue.SUPPL. 1 , pp. 160-166
    • Wozney, J.M.1
  • 22
    • 33645697787 scopus 로고    scopus 로고
    • Erratum
    • Erratum in: J Bone Joint Surg Am. 2004;86:141.
    • (2004) J Bone Joint Surg Am , vol.86 , pp. 141
  • 23
    • 0033975065 scopus 로고    scopus 로고
    • Bone morphogenetic proteins in human bone regeneration
    • Groeneveld EH, Burger EH. Bone morphogenetic proteins in human bone regeneration. Eur J Endocrinol. 2000;142:9-21.
    • (2000) Eur J Endocrinol , vol.142 , pp. 9-21
    • Groeneveld, E.H.1    Burger, E.H.2
  • 24
    • 0032101214 scopus 로고    scopus 로고
    • Bone morphogenetic proteins: From basic studies to clinical approaches
    • Sakou T, Bone morphogenetic proteins: from basic studies to clinical approaches. Bone. 1998;22:591-603.
    • (1998) Bone , vol.22 , pp. 591-603
    • Sakou, T.1
  • 25
    • 0033636449 scopus 로고    scopus 로고
    • Capacitively coupled electric fields acceler-ate proliferation of osteoblast-like primary cells and increase bone extracellular matrix formation in vitro
    • Hartig M, Joos U, Wiesmann HP Capacitively coupled electric fields acceler-ate proliferation of osteoblast-like primary cells and increase bone extracellular matrix formation in vitro. Eur Biophys J. 2000;29:499-506.
    • (2000) Eur Biophys J , vol.29 , pp. 499-506
    • Hartig, M.1    Joos, U.2    Wiesmann, H.P.3
  • 26
    • 0026475607 scopus 로고
    • In vitro bone-cell response to a capacitively coupled electrical field. The role of field strength, pulse pattern, and duty cycle
    • Brighton CT, Okereke E, Pollack SR, Clark CC. In vitro bone-cell response to a capacitively coupled electrical field. The role of field strength, pulse pattern, and duty cycle. Clin Orthop Relat Res. 1992;285:255-62.
    • (1992) Clin Orthop Relat Res , vol.285 , pp. 255-262
    • Brighton, C.T.1    Okereke, E.2    Pollack, S.R.3    Clark, C.C.4
  • 27
    • 0023912058 scopus 로고
    • Response of cultured bone cells to a capacitively coupled electric field: Inhibition of cAMP response to parathyroid hormone
    • Brighton CT, McCluskey WP Response of cultured bone cells to a capacitively coupled electric field: inhibition of cAMP response to parathyroid hormone. J Orthop Res. 1988;6:567-71.
    • (1988) J Orthop Res , vol.6 , pp. 567-571
    • Brighton, C.T.1    McCluskey, W.P.2
  • 28
    • 0028520802 scopus 로고
    • Pulsating electromagnetic field stimulates mRNA expression of bone morphogenetic protein-2 and -4
    • Nagai M, Ota M. Pulsating electromagnetic field stimulates mRNA expression of bone morphogenetic protein-2 and -4. J Dent Res. 1994;73:1601-5.
    • (1994) J Dent Res , vol.73 , pp. 1601-1605
    • Nagai, M.1    Ota, M.2
  • 29
    • 0032544350 scopus 로고    scopus 로고
    • Pulsed electromagnetic fields simultaneously induce osteogenesis and upregulate transcription of bone morphogenetic proteins 2 and 4 in rat osteoblasts in vitro
    • Bodamyali T, Bhatt B, Hughes FJ, Winrow VR, Kanczler JM, Simon B, Abbott J, Blake DR, Stevens CR. Pulsed electromagnetic fields simultaneously induce osteogenesis and upregulate transcription of bone morphogenetic proteins 2 and 4 in rat osteoblasts in vitro. Biochem Biophys Res Commun, 1998;250:458-61.
    • (1998) Biochem Biophys Res Commun , vol.250 , pp. 458-461
    • Bodamyali, T.1    Bhatt, B.2    Hughes, F.J.3    Winrow, V.R.4    Kanczler, J.M.5    Simon, B.6    Abbott, J.7    Blake, D.R.8    Stevens, C.R.9
  • 30
    • 0020678843 scopus 로고
    • In vitro differentiation and calcification in a new clonal osteogenic cell line derived from newborn mouse calvaria
    • Sudo H, Kodama HA, Amagai Y, Yamamoto S, Kasai S. In vitro differentiation and calcification in a new clonal osteogenic cell line derived from newborn mouse calvaria. J Cell Biol. 1983;96:191-8.
    • (1983) J Cell Biol , vol.96 , pp. 191-198
    • Sudo, H.1    Kodama, H.A.2    Amagai, Y.3    Yamamoto, S.4    Kasai, S.5
  • 31
    • 0026690364 scopus 로고
    • Distinct proliferative and differentiated stages of murine MC3T3-E1 cells in culture: An in vitro model of osteoblast development
    • Quarles LD, Yohay DA, Lever LW, Caton R, Wenstrup RJ. Distinct proliferative and differentiated stages of murine MC3T3-E1 cells in culture: an in vitro model of osteoblast development. J Bone Miner Res, 1992;7:683-92.
    • (1992) J Bone Miner Res , vol.7 , pp. 683-692
    • Quarles, L.D.1    Yohay, D.A.2    Lever, L.W.3    Caton, R.4    Wenstrup, R.J.5
  • 32
    • 5444228750 scopus 로고    scopus 로고
    • Up-regulation of chondrocyte matrix genes and products by electric fields
    • Wang W, Wang Z, Zhang G, Clark CC, Brighton CT. Up-regulation of chondrocyte matrix genes and products by electric fields. Clin Orthop Relat Res. 2004;427 Suppl:S163-73.
    • (2004) Clin Orthop Relat Res , vol.427 , Issue.SUPPL.
    • Wang, W.1    Wang, Z.2    Zhang, G.3    Clark, C.C.4    Brighton, C.T.5
  • 34
    • 0031577458 scopus 로고    scopus 로고
    • Electrical stimulation induces the level of TGF-beta1 mRNA in osteoblastic cells by a mechanism involving calcium/calmodulin pathway
    • Zhuang H, Wang W, Seldes RM, Tahernia AD, Fan H, Brighton CT. Electrical stimulation induces the level of TGF-beta1 mRNA in osteoblastic cells by a mechanism involving calcium/calmodulin pathway. Biochem Biophys Res Commun. 1997;237:225-9.
    • (1997) Biochem Biophys Res Commun , vol.237 , pp. 225-229
    • Zhuang, H.1    Wang, W.2    Seldes, R.M.3    Tahernia, A.D.4    Fan, H.5    Brighton, C.T.6
  • 35
    • 0030976489 scopus 로고    scopus 로고
    • Rapid isolation of total RNA from small samples of hypocellular, dense connective tissues
    • Reno C, Marchuk L, Sciore P Frank CB, Hart DA. Rapid isolation of total RNA from small samples of hypocellular, dense connective tissues. Biotechniques, 1997;22:1082-6.
    • (1997) Biotechniques , vol.22 , pp. 1082-1086
    • Reno, C.1    Marchuk, L.2    Sciore, P.3    Frank, C.B.4    Hart, D.A.5
  • 36
    • 0035090483 scopus 로고    scopus 로고
    • Quantitative analysis of gene expression in human articular cartilage from normal and osteoarthritic joints
    • Martin I, Jakob M, Schafer D, Dick W, Spagnoli G, Heberer M. Quantitative analysis of gene expression in human articular cartilage from normal and osteoarthritic joints. Osteoarthritis Cartilage, 2001;9:112-8.
    • (2001) Osteoarthritis Cartilage , vol.9 , pp. 112-118
    • Martin, I.1    Jakob, M.2    Schafer, D.3    Dick, W.4    Spagnoli, G.5    Heberer, M.6
  • 37
    • 0036278859 scopus 로고    scopus 로고
    • Gene quantification using real-time quantitative PCR: An emerging technology hits the mainstream
    • Ginzinger DG. Gene quantification using real-time quantitative PCR: an emerging technology hits the mainstream. Exp Hematol, 2002;30:503-12.
    • (2002) Exp Hematol , vol.30 , pp. 503-512
    • Ginzinger, D.G.1
  • 38
    • 0004503871 scopus 로고
    • Dissociative extraction and reconstitution of extracellular matrix components involved in local bone differentiation
    • Sampath TK, Reddi AH. Dissociative extraction and reconstitution of extracellular matrix components involved in local bone differentiation. Proc Natl Acad Sci USA. 1981;78:7599-603.
    • (1981) Proc Natl Acad Sci USA , vol.78 , pp. 7599-7603
    • Sampath, T.K.1    Reddi, A.H.2
  • 40
  • 41
    • 0018850985 scopus 로고
    • A simple, rapid, and sensitive DNA assay procedure
    • Labarca C, Paigen K. A simple, rapid, and sensitive DNA assay procedure. Anal Biochem. 1980;102:344-52.
    • (1980) Anal Biochem , vol.102 , pp. 344-352
    • Labarca, C.1    Paigen, K.2
  • 42
    • 0026068646 scopus 로고
    • Bone morphogenetic protein-2 stimulates alkaline phosphatase activity and collagen synthesis in cultured osteoblastic cells, MC3T3-E1
    • Takuwa Y, Ohse C, Wang EA, Wozney JM, Yamashita K. Bone morphogenetic protein-2 stimulates alkaline phosphatase activity and collagen synthesis in cultured osteoblastic cells, MC3T3-E1. Biochem Biophys Res Commun. 1991;174:96-101.
    • (1991) Biochem Biophys Res Commun , vol.174 , pp. 96-101
    • Takuwa, Y.1    Ohse, C.2    Wang, E.A.3    Wozney, J.M.4    Yamashita, K.5
  • 43
    • 0030995947 scopus 로고    scopus 로고
    • Interaction between soluble type I receptor for bone morphogenetic protein and bone morphogenetic protein-4
    • Natsume T, Tomita S, Iemura S, Kinto N, Yamaguchi A, Ueno N. Interaction between soluble type I receptor for bone morphogenetic protein and bone morphogenetic protein-4. J Biol Chem. 1997;272:11535-40,
    • (1997) J Biol Chem , vol.272 , pp. 11535-11540
    • Natsume, T.1    Tomita, S.2    Iemura, S.3    Kinto, N.4    Yamaguchi, A.5    Ueno, N.6
  • 45
    • 0033547411 scopus 로고    scopus 로고
    • Serial passage of MC3T3-E1 cells alters osteoblastic function and responsiveness to transforming growth factor-beta1 and bone morphogenetic protein-2
    • Chung CY, Iida-Klein A, Wyatt LE, Rudkin GH, Ishida K, Yamaguchi DT, Miller TA. Serial passage of MC3T3-E1 cells alters osteoblastic function and responsiveness to transforming growth factor-beta1 and bone morphogenetic protein-2. Biochem Biophys Res Commun. 1999;265:246-51.
    • (1999) Biochem Biophys Res Commun , vol.265 , pp. 246-251
    • Chung, C.Y.1    Iida-Klein, A.2    Wyatt, L.E.3    Rudkin, G.H.4    Ishida, K.5    Yamaguchi, D.T.6    Miller, T.A.7
  • 46
    • 0142122975 scopus 로고    scopus 로고
    • Bone morphogenetic protein-2 restores mineralization in glucocorticoid-inhibited MC3T3-E1 osteoblast cultures
    • Luppen CA, Smith E, Spevak L, Boskey AL, Frenkel B. Bone morphogenetic protein-2 restores mineralization in glucocorticoid-inhibited MC3T3-E1 osteoblast cultures, J Bone Miner Res. 2003;18:1186-97.
    • (2003) J Bone Miner Res , vol.18 , pp. 1186-1197
    • Luppen, C.A.1    Smith, E.2    Spevak, L.3    Boskey, A.L.4    Frenkel, B.5
  • 48
    • 0036655035 scopus 로고    scopus 로고
    • Effects of pulsed electromagnetic field (PEMF) stimulation on bone tissue like formation are dependent on the maturation stages of the osteoblasts
    • Diniz Ff Shomura K, Soejima K, Ito G. Effects of pulsed electromagnetic field (PEMF) stimulation on bone tissue like formation are dependent on the maturation stages of the osteoblasts. Bioelectromagnetics. 2002;23:398-405.
    • (2002) Bioelectromagnetics , vol.23 , pp. 398-405
    • Diniz, F.1    Shomura, K.2    Soejima, K.3    Ito, G.4
  • 49
    • 0033341949 scopus 로고    scopus 로고
    • Extracellular matrix-associated bone morphogenetic proteins are essential for differentiation of murine osteoblastic cells in vitro
    • Suzawa M, Takeuchi Y, Fukumoto S, Kato S, Ueno N, Miyazono K, Matsumoto T, Fujita T. Extracellular matrix-associated bone morphogenetic proteins are essential for differentiation of murine osteoblastic cells in vitro. Endocrinology, 1999;140:2125-33.
    • (1999) Endocrinology , vol.140 , pp. 2125-2133
    • Suzawa, M.1    Takeuchi, Y.2    Fukumoto, S.3    Kato, S.4    Ueno, N.5    Miyazono, K.6    Matsumoto, T.7    Fujita, T.8
  • 50
    • 0026543172 scopus 로고
    • Relationship between collagen synthesis and expression of the osteoblast phenotype in MC3T3-E1 cells
    • Franceschi RT, lyer BS. Relationship between collagen synthesis and expression of the osteoblast phenotype in MC3T3-E1 cells. J Bone Miner Res, 1992:7:235-46.
    • (1992) J Bone Miner Res , vol.7 , pp. 235-246
    • Franceschi, R.T.1    Lyer, B.S.2
  • 51
    • 0028242767 scopus 로고
    • Effects of ascorbic acid on collagen matrix formation and osteoblast differentiation in murine MC3T3-E1 cells
    • Franceschi RT, Iyer BS, Cui Y. Effects of ascorbic acid on collagen matrix formation and osteoblast differentiation in murine MC3T3-E1 cells. J Bone Miner Res. 1994;9:843-54.
    • (1994) J Bone Miner Res , vol.9 , pp. 843-854
    • Franceschi, R.T.1    Iyer, B.S.2    Cui, Y.3
  • 52
    • 0036133374 scopus 로고    scopus 로고
    • Bone morphogenetic proteins, extracellular matrix, and mitogen-activated protein kinase signaling pathways are required for osteoblast-specific gene expression and differentiation in MC3T3-E1 cells
    • Xiao G, Gopalakrishnan R, Jiang D, Reith E, Benson MD, Franceschi RT. Bone morphogenetic proteins, extracellular matrix, and mitogen-activated protein kinase signaling pathways are required for osteoblast-specific gene expression and differentiation in MC3T3-E1 cells. J Bone Miner Res. 2002;17:101-10.
    • (2002) J Bone Miner Res , vol.17 , pp. 101-110
    • Xiao, G.1    Gopalakrishnan, R.2    Jiang, D.3    Reith, E.4    Benson, M.D.5    Franceschi, R.T.6
  • 54
    • 0001783646 scopus 로고    scopus 로고
    • Bone morphogenetic proteins
    • Bilezikian JP, Raisz LG, Rodan GA, editors. San Diego: Academic Press
    • Rosen V, Wozney JM. Bone morphogenetic proteins. In: Bilezikian JP, Raisz LG, Rodan GA, editors. Principles of bone biology. 2nd ed. San Diego: Academic Press; 2002. p 919-28.
    • (2002) Principles of Bone Biology. 2nd Ed. , pp. 919-928
    • Rosen, V.1    Wozney, J.M.2
  • 55
    • 0035082809 scopus 로고    scopus 로고
    • BMP3: To be or not to be a BMRJ
    • Bahamonde ME, Lyons KM. BMP3: to be or not to be a BMRJ Bone Joint Surg Am. 2001;83 Suppl 1:356-62.
    • (2001) Bone Joint Surg Am , vol.83 , Issue.SUPPL. 1 , pp. 356-362
    • Bahamonde, M.E.1    Lyons, K.M.2
  • 56
    • 0031974284 scopus 로고    scopus 로고
    • Bone morphogenetic protein and bone morphogenetic protein gene family in bone formation and repair
    • Wozney JM, Rosen V, Bone morphogenetic protein and bone morphogenetic protein gene family in bone formation and repair. Clin Orthop Relat Res. 1998;346:26-37.
    • (1998) Clin Orthop Relat Res , vol.346 , pp. 26-37
    • Wozney, J.M.1    Rosen, V.2
  • 57
    • 0036258546 scopus 로고    scopus 로고
    • BMP-7 in orthopedic applications: A review
    • Giltaij LR. BMP-7 in orthopedic applications: a review, J Musculoskeletal Res, 2002;6:55-62.
    • (2002) J Musculoskeletal Res , vol.6 , pp. 55-62
    • Giltaij, L.R.1
  • 58
    • 22844432930 scopus 로고    scopus 로고
    • Bone morphogenetic proteins. Development and clinical efficacy in the treatment of fractures and bone defects
    • Termaat MF, Den Boer FC, Bakker FC, Patka P, Haarman HJ. Bone morphogenetic proteins. Development and clinical efficacy in the treatment of fractures and bone defects. J Bone Joint Surg Am, 2005;87:1367-78.
    • (2005) J Bone Joint Surg Am , vol.87 , pp. 1367-1378
    • Termaat, M.F.1    Den Boer, F.C.2    Bakker, F.C.3    Patka, P.4    Haarman, H.J.5


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