메뉴 건너뛰기




Volumn 1, Issue 2, 2005, Pages 149-159

Zoledronic acid: Past, present and future roles in cancer treatment

Author keywords

bisphosphonates; breast cancer; lung cancer; myeloma; prostate cancer

Indexed keywords

ANTINEOPLASTIC AGENT; BISPHOSPHONIC ACID DERIVATIVE; BONE DENSITY CONSERVATION AGENT; IMIDAZOLE DERIVATIVE; ZOLEDRONIC ACID;

EID: 33646443708     PISSN: 14796694     EISSN: 17448301     Source Type: Journal    
DOI: 10.1517/14796694.1.2.149     Document Type: Article
Times cited : (14)

References (66)
  • 2
    • 84875936880 scopus 로고    scopus 로고
    • The use of bisphosphonates in breast cancer
    • Morrow PKH, Theriault RL: The use of bisphosphonates in breast cancer. Dis. Breast 7(1), 1-14 (2004)
    • (2004) Dis. Breast , vol.7 , Issue.1 , pp. 1-14
    • Morrow, P.K.H.1    Theriault, R.L.2
  • 3
    • 0035010803 scopus 로고    scopus 로고
    • Metastatic bone disease: Clinical features, pathophysiology and treatment strategies
    • Coleman RE: Metastatic bone disease: clinical features, pathophysiology and treatment strategies. Cancer Treat. Rev. 27(3), 165-176 (2001)
    • (2001) Cancer Treat. Rev. , vol.27 , Issue.3 , pp. 165-176
    • Coleman, R.E.1
  • 4
    • 0030749321 scopus 로고    scopus 로고
    • Skeletal complications of malignancy
    • Coleman RE: Skeletal complications of malignancy. Cancer 80(8 Suppl.), 1588-1594 (1997)
    • (1997) Cancer , vol.80 , Issue.8 SUPPL. , pp. 1588-1594
    • Coleman, R.E.1
  • 5
    • 0031056437 scopus 로고    scopus 로고
    • Malignant bone pain: Pathophysiology and treatment
    • Mercadante S: Malignant bone pain: pathophysiology and treatment. Pain 69 (1-2), 1-18 (1997)
    • (1997) Pain , vol.69 , Issue.1-2 , pp. 1-18
    • Mercadante, S.1
  • 6
    • 0030749322 scopus 로고    scopus 로고
    • Overview of bisphosphonates
    • Rogers MJ, Watts DJ, Russell RG: Overview of bisphosphonates. Cancer 80(8 Suppl.), 1652-1660 (1997)
    • (1997) Cancer , vol.80 , Issue.8 SUPPL. , pp. 1652-1660
    • Rogers, M.J.1    Watts, D.J.2    Russell, R.G.3
  • 7
    • 0036148405 scopus 로고    scopus 로고
    • Development of bisphosphonates
    • Fleisch H: Development of bisphosphonates. Breast Cancer Res. 4(1), 30-34 (2002)
    • (2002) Breast Cancer Res. , vol.4 , Issue.1 , pp. 30-34
    • Fleisch, H.1
  • 9
    • 0022548092 scopus 로고
    • Quantitative morphometric evaluation of the inhibitory activity of new aminobisphosphonates on bone resorption in the rat
    • Schenk R, Eggli P, Fleisch H, Rosini S: Quantitative morphometric evaluation of the inhibitory activity of new aminobisphosphonates on bone resorption in the rat. Calcif. Tissue Int. 38(6), 342-349 (1986)
    • (1986) Calcif. Tissue Int. , vol.38 , Issue.6 , pp. 342-349
    • Schenk, R.1    Eggli, P.2    Fleisch, H.3    Rosini, S.4
  • 10
    • 0028202499 scopus 로고
    • Preclinical pharmacology of CGP 42 446, a new, potent, heterocyclic bisphosphonate compound
    • Green JR, Müller K, Jaeggi KA: Preclinical pharmacology of CGP 42 446, a new, potent, heterocyclic bisphosphonate compound. J. Bone Miner. Res. 9(5), 745-751 (1994)
    • (1994) J. Bone Miner. Res. , vol.9 , Issue.5 , pp. 745-751
    • Green, J.R.1    Müller, K.2    Jaeggi, K.A.3
  • 11
    • 84875912834 scopus 로고    scopus 로고
    • Aredia®: [package insert] East Hanover, NJ: Novartis Pharmaceuticals Corporation
    • Aredia®: [package insert]. Pamidronate disodium prescribing information. East Hanover, NJ: Novartis Pharmaceuticals Corporation; 2002.
    • (2002) Pamidronate Disodium Prescribing Information
  • 12
    • 17144447171 scopus 로고    scopus 로고
    • Intravenous ibandronate reduces the incidence of skeletal complications in patients with breast cancer and bone metastases
    • Body JJ, Diel IJ, Lichinitser MR et al.: Intravenous ibandronate reduces the incidence of skeletal complications in patients with breast cancer and bone metastases. Ann. Oncol. 14, 1399-1405 (2003)
    • (2003) Ann. Oncol. , vol.14 , pp. 1399-1405
    • Body, J.J.1    Diel, I.J.2    Lichinitser, M.R.3
  • 14
    • 20044362573 scopus 로고    scopus 로고
    • Zoledronic acid for the treatment of malignant bone disease
    • Coleman RE: Zoledronic acid for the treatment of malignant bone disease. Euro. J. Hosp. Pharm. 1, 130-138 (2004)
    • (2004) Euro. J. Hosp. Pharm. , vol.1 , pp. 130-138
    • Coleman, R.E.1
  • 15
    • 21844478012 scopus 로고    scopus 로고
    • Zoledronic acid effectively counteracts cancer treatment induced bone loss (CTIBL) in premenopausal breast cancer patients receiving adjuvant endocrine treatment with goserelin plus anastrozole versus goserelin plus tamoxifen - Bone density subprotocol results of a randomized multicenter trial (ABCSG- 12)
    • Abstract 6
    • Gnant M, Jakesz R, Mlineritsch B et al.: Zoledronic acid effectively counteracts cancer treatment induced bone loss (CTIBL) in premenopausal breast cancer patients receiving adjuvant endocrine treatment with goserelin plus anastrozole versus goserelin plus tamoxifen - bone density subprotocol results of a randomized multicenter trial (ABCSG- 12). Breast Cancer Res. Treat. 88(Suppl. 1), S8-S9. Abstract 6 (2004)
    • (2004) Breast Cancer Res. Treat. , vol.88 , Issue.SUPPL. 1
    • Gnant, M.1    Jakesz, R.2    Mlineritsch, B.3
  • 16
    • 0035960116 scopus 로고    scopus 로고
    • Pamidronate to prevent bone loss during androgen-deprivation therapy for prostate cancer
    • Smith MR, McGovern FJ, Zietman AL et al.: Pamidronate to prevent bone loss during androgen-deprivation therapy for prostate cancer. N. Engl. J. Med. 345(13), 948-955 (2001)
    • (2001) N. Engl. J. Med. , vol.345 , Issue.13 , pp. 948-955
    • Smith, M.R.1    McGovern, F.J.2    Zietman, A.L.3
  • 17
    • 0038075478 scopus 로고    scopus 로고
    • Randomized controlled trial of zoledronic acid to prevent bone loss in men receiving androgen deprivation therapy for nonmetastatic prostate cancer
    • Smith MR, Eastham J, Gleason DM, Shasha D, Tchekmedyian S, Zinner N: Randomized controlled trial of zoledronic acid to prevent bone loss in men receiving androgen deprivation therapy for nonmetastatic prostate cancer. J. Urol. 169(6), 2008-2012 (2003)
    • (2003) J. Urol. , vol.169 , Issue.6 , pp. 2008-2012
    • Smith, M.R.1    Eastham, J.2    Gleason, D.M.3    Shasha, D.4    Tchekmedyian, S.5    Zinner, N.6
  • 18
    • 0036062211 scopus 로고    scopus 로고
    • Pharmacologic profile of zoledronic acid: A highly potent inhibitor of bone resorption
    • Green JR, Rogers MJ: Pharmacologic profile of zoledronic acid: a highly potent inhibitor of bone resorption. Drug Dev. Res. 55, 210-224 (2002)
    • (2002) Drug Dev. Res. , vol.55 , pp. 210-224
    • Green, J.R.1    Rogers, M.J.2
  • 19
    • 0037455013 scopus 로고    scopus 로고
    • Human T-cell receptor gammadelta cells recognize endogenous mevalonate metabolites in tumor cells
    • Gober HJ, Kistowska M, Angman L, Jeno P, Mori L, De Libero G: Human T-cell receptor gammadelta cells recognize endogenous mevalonate metabolites in tumor cells. J. Exp. Med. 197(2), 163-168 (2003)
    • (2003) J. Exp. Med. , vol.197 , Issue.2 , pp. 163-168
    • Gober, H.J.1    Kistowska, M.2    Angman, L.3    Jeno, P.4    Mori, L.5    De Libero, G.6
  • 20
    • 0031977199 scopus 로고    scopus 로고
    • Nitrogencontaining bisphosphonates inhibit the mevalonate pathway and prevent posttranslational prenylation of GTP-binding proteins, including Ras
    • Luckman SP, Hughes DE, Coxon FP, Graham R, Russell G, Rogers MJ: Nitrogencontaining bisphosphonates inhibit the mevalonate pathway and prevent posttranslational prenylation of GTP-binding proteins, including Ras. J. Bone Miner. Res. 13(4), 581-589 (1998)
    • (1998) J. Bone Miner. Res. , vol.13 , Issue.4 , pp. 581-589
    • Luckman, S.P.1    Hughes, D.E.2    Coxon, F.P.3    Graham, R.4    Russell, G.5    Rogers, M.J.6
  • 21
    • 0032929644 scopus 로고    scopus 로고
    • Molecular mechanisms of action of bisphosphonates
    • Rogers MJ, Frith JC, Luckman SP et al.: Molecular mechanisms of action of bisphosphonates. Bone 24(Suppl.), 73S-79S (1999)
    • (1999) Bone , vol.24 , Issue.SUPPL.
    • Rogers, M.J.1    Frith, J.C.2    Luckman, S.P.3
  • 22
    • 0032859149 scopus 로고    scopus 로고
    • The pharmacology of bisphosphonates and new insights into their mechanisms of action
    • Russell RG, Rogers MJ, Frith JC et al.: The pharmacology of bisphosphonates and new insights into their mechanisms of action. J. Bone Miner. Res. 14(Suppl. 2), 53-65 (1999)
    • (1999) J. Bone Miner. Res. , vol.14 , Issue.SUPPL. 2 , pp. 53-65
    • Russell, R.G.1    Rogers, M.J.2    Frith, J.C.3
  • 23
    • 0034659773 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of action of bisphosphonates
    • Rogers MJ, Gordon S, Benford HL et al.: Cellular and molecular mechanisms of action of bisphosphonates. Cancer 88(12 Suppl.), 2961-2978 (2000)
    • (2000) Cancer , vol.88 , Issue.12 SUPPL. , pp. 2961-2978
    • Rogers, M.J.1    Gordon, S.2    Benford, H.L.3
  • 24
    • 0033620684 scopus 로고    scopus 로고
    • Farnesyltransferase inhibitors: Targeting the molecular basis of cancer
    • Oliff A: Farnesyltransferase inhibitors: targeting the molecular basis of cancer. Biochim. Biophys. Acta 1423, C19-C30 (1999)
    • (1999) Biochim. Biophys. Acta , vol.1423
    • Oliff, A.1
  • 25
    • 0029898894 scopus 로고    scopus 로고
    • Protein prenylation: Molecular mechanisms and functional consequences
    • Zhang FL, Casey PJ: Protein prenylation: molecular mechanisms and functional consequences. Ann. Rev. Biochem. 65, 241-269 (1996)
    • (1996) Ann. Rev. Biochem. , vol.65 , pp. 241-269
    • Zhang, F.L.1    Casey, P.J.2
  • 26
    • 0031754521 scopus 로고    scopus 로고
    • Heterocycle-containing bisphosphonates cause apoptosis and inhibit bone resorption by preventing protein prenylation: Evidence from structure-activity relationships in J774 macrophages
    • Luckman SP, Coxon FP, Ebetino FH, Russell G, Rogers MJ: Heterocycle-containing bisphosphonates cause apoptosis and inhibit bone resorption by preventing protein prenylation: evidence from structure-activity relationships in J774 macrophages. J. Bone Miner. Res. 13(11), 1668-1678 (1998)
    • (1998) J. Bone Miner. Res. , vol.13 , Issue.11 , pp. 1668-1678
    • Luckman, S.P.1    Coxon, F.P.2    Ebetino, F.H.3    Russell, G.4    Rogers, M.J.5
  • 27
    • 0035146537 scopus 로고    scopus 로고
    • Structure-activity relationships for inhibition of farnesyl diphosphate synthase in vitro and inhibition of bone resorption in vivo by nitrogen-containing bisphosphonates
    • Dunford JE, Thompson K, Coxon FP et al.: Structure-activity relationships for inhibition of farnesyl diphosphate synthase in vitro and inhibition of bone resorption in vivo by nitrogen-containing bisphosphonates. J. Pharmacol. Exp. Ther. 296(2), 235-242 (2001)
    • (2001) J. Pharmacol. Exp. Ther. , vol.296 , Issue.2 , pp. 235-242
    • Dunford, J.E.1    Thompson, K.2    Coxon, F.P.3
  • 28
    • 18644373689 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of zoledronic acid in cancer patients with bone metastases
    • Chen T, Berenson J, Vescio R et al.: Pharmacokinetics and pharmacodynamics of zoledronic acid in cancer patients with bone metastases. J. Clin. Pharmacol. 42(11), 1228-1236 (2002)
    • (2002) J. Clin. Pharmacol. , vol.42 , Issue.11 , pp. 1228-1236
    • Chen, T.1    Berenson, J.2    Vescio, R.3
  • 29
    • 0029886359 scopus 로고    scopus 로고
    • Bisphosphonates: A review of their pharmacokinetic properties
    • Lin JH: Bisphosphonates: a review of their pharmacokinetic properties. Bone 18(2), 75-85 (1996)
    • (1996) Bone , vol.18 , Issue.2 , pp. 75-85
    • Lin, J.H.1
  • 31
    • 0035863508 scopus 로고    scopus 로고
    • Zoledronic acid is superior to pamidronate in the treatment of hypercalcemia of malignancy: A pooled analysis of two randomized, controlled clinical trials
    • Major P, Lortholary A, Hon J et al.: Zoledronic acid is superior to pamidronate in the treatment of hypercalcemia of malignancy: a pooled analysis of two randomized, controlled clinical trials. J. Clin. Oncol. 19(2), 558-567 (2001)
    • (2001) J. Clin. Oncol. , vol.19 , Issue.2 , pp. 558-567
    • Major, P.1    Lortholary, A.2    Hon, J.3
  • 32
    • 0035174823 scopus 로고    scopus 로고
    • A phase I, open label, dose ranging trial of intravenous bolus zoledronic acid, a novel bisphosphonate, in cancer patients with metastatic bone disease
    • Berenson JR, Vescio R, Henick K et al.: A phase I, open label, dose ranging trial of intravenous bolus zoledronic acid, a novel bisphosphonate, in cancer patients with metastatic bone disease. Cancer 91(1), 144-154 (2001)
    • (2001) Cancer , vol.91 , Issue.1 , pp. 144-154
    • Berenson, J.R.1    Vescio, R.2    Henick, K.3
  • 33
    • 0034906503 scopus 로고    scopus 로고
    • A phase i dose-ranging trial of monthly infusions of zoledronic acid for the treatment of osteolytic bone metastases
    • Berenson JR, Vescio RA, Rosen LS et al.: A phase I dose-ranging trial of monthly infusions of zoledronic acid for the treatment of osteolytic bone metastases. Clin. Cancer Res. 7(3), 478-485 (2001)
    • (2001) Clin. Cancer Res. , vol.7 , Issue.3 , pp. 478-485
    • Berenson, J.R.1    Vescio, R.A.2    Rosen, L.S.3
  • 34
    • 0035312469 scopus 로고    scopus 로고
    • Zoledronic acid reduces skeletal-related events in patients with osteolytic metastases
    • Berenson JR, Rosen LS, Howell A et al.: Zoledronic acid reduces skeletal-related events in patients with osteolytic metastases. Cancer 91(7), 1191-1200 (2001)
    • (2001) Cancer , vol.91 , Issue.7 , pp. 1191-1200
    • Berenson, J.R.1    Rosen, L.S.2    Howell, A.3
  • 35
    • 0035463593 scopus 로고    scopus 로고
    • Zoledronic acid versus pamidronate in the treatment of skeletal metastases in patients with breast cancer or osteolytic lesions of multiple myeloma: A phase III, double-blind, comparative trial
    • Rosen LS, Gordon D, Kaminski M et al.: Zoledronic acid versus pamidronate in the treatment of skeletal metastases in patients with breast cancer or osteolytic lesions of multiple myeloma: a phase III, double-blind, comparative trial. Cancer J. 7(5), 377-387 (2001)
    • (2001) Cancer J. , vol.7 , Issue.5 , pp. 377-387
    • Rosen, L.S.1    Gordon, D.2    Kaminski, M.3
  • 36
    • 10744233021 scopus 로고    scopus 로고
    • Long-term efficacy and safety of zoledronic acid compared with pamidronate disodium in the treatment of skeletal complications in patients with advanced multiple myeloma or breast carcinoma: A randomized, doubleblind, multicenter, comparative trial
    • Rosen LS, Gordon D, Kaminski M et al.: Long-term efficacy and safety of zoledronic acid compared with pamidronate disodium in the treatment of skeletal complications in patients with advanced multiple myeloma or breast carcinoma: a randomized, doubleblind, multicenter, comparative trial. Cancer 98(8), 1735-1744 (2003)
    • (2003) Cancer , vol.98 , Issue.8 , pp. 1735-1744
    • Rosen, L.S.1    Gordon, D.2    Kaminski, M.3
  • 37
    • 0037009822 scopus 로고    scopus 로고
    • A randomized, placebo-controlled trial of zoledronic acid in patients with hormonerefractory metastatic prostate carcinoma
    • Saad F, Gleason DM, Murray R et al.: A randomized, placebo-controlled trial of zoledronic acid in patients with hormonerefractory metastatic prostate carcinoma. J. Natl Cancer Inst. 94(19), 1458-1468 (2002)
    • (2002) J. Natl Cancer Inst. , vol.94 , Issue.19 , pp. 1458-1468
    • Saad, F.1    Gleason, D.M.2    Murray, R.3
  • 38
    • 2942518111 scopus 로고    scopus 로고
    • Longterm efficacy of zoledronic acid for the prevention of skeletal complications in patients with metastatic hormone-refractory prostate cancer
    • Saad F, Gleason DM, Murray R et al.: Longterm efficacy of zoledronic acid for the prevention of skeletal complications in patients with metastatic hormone-refractory prostate cancer. J. Natl Cancer Inst. 96(11), 879-882 (2004)
    • (2004) J. Natl Cancer Inst. , vol.96 , Issue.11 , pp. 879-882
    • Saad, F.1    Gleason, D.M.2    Murray, R.3
  • 39
    • 0042914647 scopus 로고    scopus 로고
    • Zoledronic acid versus placebo in the treatment of skeletal metastases in patients with lung cancer and other solid tumors: A phase III, double-blind, randomized trial
    • Zoledronic Acid Lung Cancer and Other Solid Tumors Study Group
    • Rosen LS, Gordon D, Tchekmedyian S et al.: Zoledronic acid versus placebo in the treatment of skeletal metastases in patients with lung cancer and other solid tumors: a phase III, double-blind, randomized trial- the Zoledronic Acid Lung Cancer and Other Solid Tumors Study Group. J. Clin. Oncol. 21(16), 3150-3157 (2003)
    • (2003) J. Clin. Oncol. , vol.21 , Issue.16 , pp. 3150-3157
    • Rosen, L.S.1    Gordon, D.2    Tchekmedyian, S.3
  • 40
    • 2642521168 scopus 로고    scopus 로고
    • Long-term efficacy and safety of zoledronic acid in the treatment of skeletal metastases in patients with nonsmall cell lung carcinoma and other solid tumors: A randomized, phase III, double-blind, placebocontrolled trial
    • Rosen LS, Gordon D, Tchekmedyian NS et al.: Long-term efficacy and safety of zoledronic acid in the treatment of skeletal metastases in patients with nonsmall cell lung carcinoma and other solid tumors: a randomized, phase III, double-blind, placebocontrolled trial. Cancer 100(12), 2613-2621 (2004)
    • (2004) Cancer , vol.100 , Issue.12 , pp. 2613-2621
    • Rosen, L.S.1    Gordon, D.2    Tchekmedyian, N.S.3
  • 41
    • 0001646484 scopus 로고
    • Coxs regression model for counting processes: A large sample study
    • Andersen PK, Gill RD: Coxs regression model for counting processes: a large sample study. Ann Stats. 10(4), 1100-1120 (1982)
    • (1982) Ann Stats. , vol.10 , Issue.4 , pp. 1100-1120
    • Andersen, P.K.1    Gill, R.D.2
  • 42
    • 0036903764 scopus 로고    scopus 로고
    • Efficacy of bisphosphonates in the management of skeletal complications of bone metastases and selection of clinical endpoints
    • Major PP, Cook R: Efficacy of bisphosphonates in the management of skeletal complications of bone metastases and selection of clinical endpoints. Am. J. Clin. Oncol. 25(6 Suppl. 1), S10-S18 (2002)
    • (2002) Am. J. Clin. Oncol. , vol.25 , Issue.6 SUPPL. 1
    • Major, P.P.1    Cook, R.2
  • 43
    • 6844252283 scopus 로고    scopus 로고
    • Long-term pamidronate treatment of advanced multiple myeloma patients reduces skeletal events
    • Berenson JR, Lichtenstein A, Porter L et al.: Long-term pamidronate treatment of advanced multiple myeloma patients reduces skeletal events. J. Clin. Oncol. 16(2), 593-602 (1998)
    • (1998) J. Clin. Oncol. , vol.16 , Issue.2 , pp. 593-602
    • Berenson, J.R.1    Lichtenstein, A.2    Porter, L.3
  • 44
    • 7144223389 scopus 로고    scopus 로고
    • Long-term prevention of skeletal complications of metastatic breast cancer with pamidronate
    • Hortobagyi GN, Theriault RL, Lipton A et al.: Long-term prevention of skeletal complications of metastatic breast cancer with pamidronate. J. Clin. Oncol. 16(6), 2038-2044 (1998)
    • (1998) J. Clin. Oncol. , vol.16 , Issue.6 , pp. 2038-2044
    • Hortobagyi, G.N.1    Theriault, R.L.2    Lipton, A.3
  • 45
    • 0033050818 scopus 로고    scopus 로고
    • Pamidronate reduces skeletal morbidity in women with advanced breast cancer and lytic bone lesions: A randomized, placebocontrolled trial
    • Theriault RL, Lipton A, Hortobagyi GN et al.: Pamidronate reduces skeletal morbidity in women with advanced breast cancer and lytic bone lesions: a randomized, placebocontrolled trial. J. Clin. Oncol. 17(3), 846-854 (1999)
    • (1999) J. Clin. Oncol. , vol.17 , Issue.3 , pp. 846-854
    • Theriault, R.L.1    Lipton, A.2    Hortobagyi, G.N.3
  • 46
    • 0034162528 scopus 로고    scopus 로고
    • Pamidronate prevents skeletal complications and is effective palliative treatment in women with breast carcinoma and osteolytic bone metastases: Long term follow-up of two randomized, placebocontrolled trials
    • Lipton A, Theriault RL, Hortobagyi GN et al.: Pamidronate prevents skeletal complications and is effective palliative treatment in women with breast carcinoma and osteolytic bone metastases: long term follow-up of two randomized, placebocontrolled trials. Cancer 88(5), 1082-1090 (2000)
    • (2000) Cancer , vol.88 , Issue.5 , pp. 1082-1090
    • Lipton, A.1    Theriault, R.L.2    Hortobagyi, G.N.3
  • 47
    • 17544362366 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled phase III trial of zoledronic acid in the prevention of skeletal complications in Japanese women with bone metastases from breast cancer
    • [Abstract 668]
    • Kohno N, Aogi K, Minami H et al.: A randomized, double-blind, placebo-controlled phase III trial of zoledronic acid in the prevention of skeletal complications in Japanese women with bone metastases from breast cancer. Proc. Am. Soc. Clin. Oncol. 23(14 Suppl.),43 [Abstract 668] (2004)
    • (2004) Proc. Am. Soc. Clin. Oncol. , vol.23 , Issue.14 SUPPL. , pp. 43
    • Kohno, N.1    Aogi, K.2    Minami, H.3
  • 48
    • 0041386301 scopus 로고    scopus 로고
    • Zoledronic acid delays the onset of skeletal-related events and progression of skeletal disease in patients with advanced renal cell carcinoma
    • Lipton A, Zheng M, Seaman J: Zoledronic acid delays the onset of skeletal-related events and progression of skeletal disease in patients with advanced renal cell carcinoma. Cancer 98(5), 962-969 (2003)
    • (2003) Cancer , vol.98 , Issue.5 , pp. 962-969
    • Lipton, A.1    Zheng, M.2    Seaman, J.3
  • 49
    • 33646774940 scopus 로고    scopus 로고
    • Zoledronic acid inhibits cancer treatmentinduced bone loss in premenopausal patients with breast cancer who are receiving adjuvant endocrine treatment
    • [Abstract 103]
    • Gnant M, Jakesz R, Mlineritsch B et al.: Zoledronic acid inhibits cancer treatmentinduced bone loss in premenopausal patients with breast cancer who are receiving adjuvant endocrine treatment. The Breast 14(Suppl. 1), S44 [Abstract 103] (2005)
    • (2005) The Breast , vol.14 , Issue.SUPPL. 1
    • Gnant, M.1    Jakesz, R.2    Mlineritsch, B.3
  • 50
    • 0032758687 scopus 로고    scopus 로고
    • Comparative tolerability of drug therapies for hypercalcaemia of malignancy
    • Zojer N, Keck AV, Pecherstorfer M: Comparative tolerability of drug therapies for hypercalcaemia of malignancy. Drug Saf. 21(5), 389-406 (1999)
    • (1999) Drug Saf. , vol.21 , Issue.5 , pp. 389-406
    • Zojer, N.1    Keck, A.V.2    Pecherstorfer, M.3
  • 52
    • 0035879143 scopus 로고    scopus 로고
    • Safety and efficacy of bisphosphonates beyond 24 months in cancer patients
    • Ali SM, Esteva FJ, Hortobagyi G et al.: Safety and efficacy of bisphosphonates beyond 24 months in cancer patients. J. Clin. Oncol. 19(14), 3434-3437 (2001)
    • (2001) J. Clin. Oncol. , vol.19 , Issue.14 , pp. 3434-3437
    • Ali, S.M.1    Esteva, F.J.2    Hortobagyi, G.3
  • 53
    • 2142817155 scopus 로고    scopus 로고
    • Osteonecrosis of the jaws associated with the use of bisphosphonates: A review of 63 cases
    • Ruggiero SL, Mehrotra B, Rosenberg TJ, Engroff SL: Osteonecrosis of the jaws associated with the use of bisphosphonates: a review of 63 cases. J. Oral Maxillofac. Surg. 62(5), 527-534 (2004)
    • (2004) J. Oral Maxillofac. Surg. , vol.62 , Issue.5 , pp. 527-534
    • Ruggiero, S.L.1    Mehrotra, B.2    Rosenberg, T.J.3    Engroff, S.L.4
  • 54
    • 0020031043 scopus 로고
    • Osteonecrosis of the jaws: A complication of cancer chemotherapy
    • Schwartz HC: Osteonecrosis of the jaws: a complication of cancer chemotherapy. Head Neck Surg. 4(3), 251-253 (1982)
    • (1982) Head Neck Surg. , vol.4 , Issue.3 , pp. 251-253
    • Schwartz, H.C.1
  • 55
  • 57
    • 20044394180 scopus 로고    scopus 로고
    • Impact of skeletal complications on total medical care costs in prostate cancer patients with bone metastases
    • [Abstract 6057]
    • McKiernan JM, Delea TE, Liss M et al.: Impact of skeletal complications on total medical care costs in prostate cancer patients with bone metastases. Proc. Am. Soc. Clin. Oncol. 23, 531 [Abstract 6057] (2004)
    • (2004) Proc. Am. Soc. Clin. Oncol , vol.23 , pp. 531
    • McKiernan, J.M.1    Delea, T.E.2    Liss, M.3
  • 58
    • 5644266867 scopus 로고    scopus 로고
    • Effects of skeletal complications on total medical care costs in women with bone metastases of breast cancer
    • [Abstract 68]
    • Delea T, James M, Liss M et al.: Effects of skeletal complications on total medical care costs in women with bone metastases of breast cancer. Bone 34, S86 [Abstract 68] (2004)
    • (2004) Bone , vol.34
    • Delea, T.1    James, M.2    Liss, M.3
  • 60
    • 0642342669 scopus 로고    scopus 로고
    • American Society of Clinical Oncology 2003 update on the role of bisphosphonates and bone health issues in women with breast cancer
    • Hillner BE, Ingle JN, Chlebowski RT et al.: American Society of Clinical Oncology 2003 update on the role of bisphosphonates and bone health issues in women with breast cancer. J. Clin. Oncol. 21(21), 4042-4057 (2003)
    • (2003) J. Clin. Oncol. , vol.21 , Issue.21 , pp. 4042-4057
    • Hillner, B.E.1    Ingle, J.N.2    Chlebowski, R.T.3
  • 61
    • 0027531814 scopus 로고
    • Doubleblind controlled trial of oral clodronate in patients with bone metastases from breast cancer
    • Paterson AHG, Powles TJ, Kanis JA, McCloskey E, Hanson J, Ashley S: Doubleblind controlled trial of oral clodronate in patients with bone metastases from breast cancer. J. Clin. Oncol. 11(1), 59-65 (1993)
    • (1993) J. Clin. Oncol. , vol.11 , Issue.1 , pp. 59-65
    • Ahg, P.1    Powles, T.J.2    Kanis, J.A.3    McCloskey, E.4    Hanson, J.5    Ashley, S.6
  • 62
    • 1942501727 scopus 로고    scopus 로고
    • Oral ibandronate reduces the risk of skeletal complications in breast cancer patients with metastatic bone disease: Results from two randomised, placebo-controlled phase III studies
    • Body JJ, Diel IJ, Lichinitzer M et al.: Oral ibandronate reduces the risk of skeletal complications in breast cancer patients with metastatic bone disease: results from two randomised, placebo-controlled phase III studies. Br. J. Cancer 90(6), 1133-1137 (2004)
    • (2004) Br. J. Cancer , vol.90 , Issue.6 , pp. 1133-1137
    • Body, J.J.1    Diel, I.J.2    Lichinitzer, M.3
  • 64
    • 21344437620 scopus 로고    scopus 로고
    • Association between androgen deprivation therapy and fracture risk: A population-based cohort study in men with non-metastatic prostate cancer
    • [Abstract 4507]
    • Smith MR, Lee WC, Krupsi T et al.: Association between androgen deprivation therapy and fracture risk: a population-based cohort study in men with non-metastatic prostate cancer. Proc. Am. Soc. Clin. Oncol. 23, 382 [Abstract 4507] (2004)
    • (2004) Proc. Am. Soc. Clin. Oncol. , vol.23 , pp. 382
    • Smith, M.R.1    Lee, W.C.2    Krupsi, T.3
  • 66
    • 0037277846 scopus 로고    scopus 로고
    • The antitumor potential of bisphosphonates
    • Clezardin P: The antitumor potential of bisphosphonates. Semin. Oncol. 29(Suppl. 21), 33-42 (2002)
    • (2002) Semin. Oncol. , vol.29 , Issue.SUPPL. 21 , pp. 33-42
    • Clezardin, P.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.