-
1
-
-
0035080531
-
Peptide deformylase as an antibacterial drug target: Target validation and resistance development
-
Apfel, C. M., H. Locher, S. Evers, B. Takács, C. Hubschwerlen, W. Pirson, M. G. P. Page, and W. Keck. 2001. Peptide deformylase as an antibacterial drug target: target validation and resistance development. Antimicrob. Agents Chemother. 45:1058-1064.
-
(2001)
Antimicrob. Agents Chemother.
, vol.45
, pp. 1058-1064
-
-
Apfel, C.M.1
Locher, H.2
Evers, S.3
Takács, B.4
Hubschwerlen, C.5
Pirson, W.6
Page, M.G.P.7
Keck, W.8
-
2
-
-
0015861886
-
Cleavage of the N-terminal formylmethionine residue from a bacteriophage coat protein in vitro
-
Ball, L. A., and P. Kaesberg. 1973. Cleavage of the N-terminal formylmethionine residue from a bacteriophage coat protein in vitro. J. Mol. Biol. 79:531-537.
-
(1973)
J. Mol. Biol.
, vol.79
, pp. 531-537
-
-
Ball, L.A.1
Kaesberg, P.2
-
3
-
-
0037345802
-
The role of peptide deformylase in protein biosynthesis: A proteomic study
-
Bandow, J. E., D. Becher, K. Buttner, F. Hochgrafe, C. Freiberg, H. Brotz, and M. Hecker. 2003. The role of peptide deformylase in protein biosynthesis: a proteomic study. Proteomics 3:299-306.
-
(2003)
Proteomics
, vol.3
, pp. 299-306
-
-
Bandow, J.E.1
Becher, D.2
Buttner, K.3
Hochgrafe, F.4
Freiberg, C.5
Brotz, H.6
Hecker, M.7
-
4
-
-
0037417075
-
Proteomic approach to understanding antibiotic action
-
Bandow, J. E., H. Brötz, L. I. O. Leichert, H. Labischinski, and M. Hecker. 2003. Proteomic approach to understanding antibiotic action. Antimicrob. Agents Chemother. 47:948-955.
-
(2003)
Antimicrob. Agents Chemother.
, vol.47
, pp. 948-955
-
-
Bandow, J.E.1
Brötz, H.2
Leichert, L.I.O.3
Labischinski, H.4
Hecker, M.5
-
5
-
-
16244411296
-
Comparative antimicrobial characterization of LBM415 (NVP PDF-713), a new peptide deformylase inhibitor of clinical importance
-
Fritsche, T. R., H. S. Sader, R. Cleeland, and R. N. Jones. 2005. Comparative antimicrobial characterization of LBM415 (NVP PDF-713), a new peptide deformylase inhibitor of clinical importance. Antimicrob. Agents Chemother. 49:1468-1476.
-
(2005)
Antimicrob. Agents Chemother.
, vol.49
, pp. 1468-1476
-
-
Fritsche, T.R.1
Sader, H.S.2
Cleeland, R.3
Jones, R.N.4
-
6
-
-
0042769340
-
Subinhibitory concentrations of the deformylase inhibitor actinonin increase bacterial release of neutrophil-activating peptides: A new approach to antimicrobial chemotherapy
-
Fu, H., C. Dahlgren, and J. Bylund. 2003. Subinhibitory concentrations of the deformylase inhibitor actinonin increase bacterial release of neutrophil-activating peptides: a new approach to antimicrobial chemotherapy. Antimicrob. Agents Chemother. 47:2545-2550.
-
(2003)
Antimicrob. Agents Chemother.
, vol.47
, pp. 2545-2550
-
-
Fu, H.1
Dahlgren, C.2
Bylund, J.3
-
7
-
-
0034329475
-
Identification of eukaryotic peptide deformylases reveals universality of N-terminal protein processing mechanisms
-
Giglione, C., A. Serero, M. Pierre, B. Boisson, and T. Meinnel. 2000. Identification of eukaryotic peptide deformylases reveals universality of N-terminal protein processing mechanisms. EMBO J. 19:5916-5929.
-
(2000)
EMBO J.
, vol.19
, pp. 5916-5929
-
-
Giglione, C.1
Serero, A.2
Pierre, M.3
Boisson, B.4
Meinnel, T.5
-
8
-
-
0033936704
-
Peptide deformylase as a target for new generation, broad spectrum antimicrobial agents
-
Giglione, C., M. Pierre, and T. Meinnel. 2000. Peptide deformylase as a target for new generation, broad spectrum antimicrobial agents. Mol. Microbiol. 36:1197-1205.
-
(2000)
Mol. Microbiol.
, vol.36
, pp. 1197-1205
-
-
Giglione, C.1
Pierre, M.2
Meinnel, T.3
-
9
-
-
0015505522
-
Removal of formylmethionine residue from nascent bacteriophage f2 protein
-
Housman, D., D. Gillespie, and H. F. Lodish. 1972. Removal of formylmethionine residue from nascent bacteriophage f2 protein. J. Mol. Biol. 65:163-166.
-
(1972)
J. Mol. Biol.
, vol.65
, pp. 163-166
-
-
Housman, D.1
Gillespie, D.2
Lodish, H.F.3
-
10
-
-
21244469469
-
Bacterial peptide deformylase inhibitors: A new class of antibacterial agents
-
Jain, R., D. Chen, R. J. White, D. V. Patel, and Z. Yuan. 2005. Bacterial peptide deformylase inhibitors: a new class of antibacterial agents. Curr. Med. Chem. 12:763-771.
-
(2005)
Curr. Med. Chem.
, vol.12
, pp. 763-771
-
-
Jain, R.1
Chen, D.2
White, R.J.3
Patel, D.V.4
Yuan, Z.5
-
11
-
-
2442707806
-
Potential utility of a peptide deformylase inhibitor (NVP PDF-713) against oxazolidinone-resistant or streptogramin-resistant Gram-positive organism isolates
-
Jones, R. N., G. J. Meet, H. S. Sader, and T. R. Pritsche. 2004. Potential utility of a peptide deformylase inhibitor (NVP PDF-713) against oxazolidinone-resistant or streptogramin-resistant Gram-positive organism isolates. J. Antimicrob. Chemother. 53:804-807.
-
(2004)
J. Antimicrob. Chemother.
, vol.53
, pp. 804-807
-
-
Jones, R.N.1
Meet, G.J.2
Sader, H.S.3
Pritsche, T.R.4
-
12
-
-
0020610320
-
The toxic shock syndrome exotoxin structural gene is not detectably transmitted by a prophage
-
Kreiswirth, B. N., S. Lofdahl, M. J. Betley, M. O'Reilly, P. M. Schlievert, M. S. Bergdoll, and R. P. Novick. 1983. The toxic shock syndrome exotoxin structural gene is not detectably transmitted by a prophage. Nature 305:709.
-
(1983)
Nature
, vol.305
, pp. 709
-
-
Kreiswirth, B.N.1
Lofdahl, S.2
Betley, M.J.3
O'Reilly, M.4
Schlievert, P.M.5
Bergdoll, M.S.6
Novick, R.P.7
-
13
-
-
9644268250
-
Human mitochondrial peptide deformylase, a new anticancer target of actinonin-hased antibiotics
-
Lee, M. D., Y. She, M. J. Soskis, C. P. Borella, J. R. Gardner, P. A. Hayes, B. M. Dy, M. L. Heaney, M. R. Philips, W. G. Bornmann, F. M. Sirotnak, and D. A. Scheinberg. 2004. Human mitochondrial peptide deformylase, a new anticancer target of actinonin-hased antibiotics. J. Clin. Investig. 114:1107-1116.
-
(2004)
J. Clin. Investig.
, vol.114
, pp. 1107-1116
-
-
Lee, M.D.1
She, Y.2
Soskis, M.J.3
Borella, C.P.4
Gardner, J.R.5
Hayes, P.A.6
Dy, B.M.7
Heaney, M.L.8
Philips, M.R.9
Bornmann, W.G.10
Sirotnak, F.M.11
Scheinberg, D.A.12
-
14
-
-
0033919993
-
Peptide deformylase in Staphylococcus aureus: Resistance to inhibition is mediated by mutations in the formyltransferase gene
-
Margolis, P. S., C. J. Hackbarth, D. C. Young, W. Wang, D. Chen, Z. Yuan, R. White, and J. Trias. 2000. Peptide deformylase in Staphylococcus aureus: resistance to inhibition is mediated by mutations in the formyltransferase gene. Antimicrob. Agents Chemother. 44:1825-1831.
-
(2000)
Antimicrob. Agents Chemother.
, vol.44
, pp. 1825-1831
-
-
Margolis, P.S.1
Hackbarth, C.J.2
Young, D.C.3
Wang, W.4
Chen, D.5
Yuan, Z.6
White, R.7
Trias, J.8
-
15
-
-
0034878770
-
Resistance of Streptococcus pneumoniae to deformylase inhibitors is due to mutations in defB
-
Margolis, P., C. Hackbarth, S. Lopez, M. Maniar, W. Wang, Z. Yuan, R. White, and J. Trias. 2001. Resistance of Streptococcus pneumoniae to deformylase inhibitors is due to mutations in defB. Antimicrob. Agents Chemother. 45:2432-2435.
-
(2001)
Antimicrob. Agents Chemother.
, vol.45
, pp. 2432-2435
-
-
Margolis, P.1
Hackbarth, C.2
Lopez, S.3
Maniar, M.4
Wang, W.5
Yuan, Z.6
White, R.7
Trias, J.8
-
16
-
-
0028053015
-
Genetic characterization of polypeptide deformylase, a distinctive enzyme of eubacterial translation
-
Mazel, D., S. Pochet, and P. Marliere. 1994. Genetic characterization of polypeptide deformylase, a distinctive enzyme of eubacterial translation. EMBO J. 13:914-923.
-
(1994)
EMBO J.
, vol.13
, pp. 914-923
-
-
Mazel, D.1
Pochet, S.2
Marliere, P.3
-
18
-
-
0027882514
-
Methionine as translation start signal: A review of the enzymes of the pathway in Escherichia coli
-
Meinnel, T., Y. Mechulam, and S. Blanquet. 1993. Methionine as translation start signal: a review of the enzymes of the pathway in Escherichia coli. Biochimie 75:1061-1075.
-
(1993)
Biochimie
, vol.75
, pp. 1061-1075
-
-
Meinnel, T.1
Mechulam, Y.2
Blanquet, S.3
-
19
-
-
0042473206
-
Characterization of a human peptide deformylase: Implications for antibacterial drug design
-
Nguyen, K. T., X. Hu, C. Colton, R. Chakrabarti, M. X. Zhu, and D. Pei. 2003. Characterization of a human peptide deformylase: implications for antibacterial drug design. Biochemistry 42:9952-9958.
-
(2003)
Biochemistry
, vol.42
, pp. 9952-9958
-
-
Nguyen, K.T.1
Hu, X.2
Colton, C.3
Chakrabarti, R.4
Zhu, M.X.5
Pei, D.6
-
20
-
-
0030793842
-
Mechanism of action of oxazolidinones: Effects of linezolid and eperezolid on translation reactions
-
Shinabarger, D. L., K. R. Marotti, R. W. Murray, A. H. Lin, E. P. Melchior, S. M. Swaney, D. S. Dunyak, W. F. Demyan, and J. M. Buysse. 1997. Mechanism of action of oxazolidinones: effects of linezolid and eperezolid on translation reactions. Antimicrob. Agents Chemother. 41:2132-2136.
-
(1997)
Antimicrob. Agents Chemother.
, vol.41
, pp. 2132-2136
-
-
Shinabarger, D.L.1
Marotti, K.R.2
Murray, R.W.3
Lin, A.H.4
Melchior, E.P.5
Swaney, S.M.6
Dunyak, D.S.7
Demyan, W.F.8
Buysse, J.M.9
-
21
-
-
0347566333
-
Expression of N-formylated proteins in Escherichia coli
-
Specter, S., J. M. Flynn, B. Tidor, T. A. Baker, and R. T. Sauer. 2003. Expression of N-formylated proteins in Escherichia coli. Protein Expr. Purif. 32:317-322.
-
(2003)
Protein Expr. Purif.
, vol.32
, pp. 317-322
-
-
Specter, S.1
Flynn, J.M.2
Tidor, B.3
Baker, T.A.4
Sauer, R.T.5
-
22
-
-
0035885234
-
Deformylase as a novel antibacterial target
-
Yuan, Z., J. Trias, and R. J. White. 2001. Deformylase as a novel antibacterial target. Drug Discov. Today 6:954-961.
-
(2001)
Drug Discov. Today
, vol.6
, pp. 954-961
-
-
Yuan, Z.1
Trias, J.2
White, R.J.3
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