Effect of fatty acids, glucose, and insulin on hepatic glucose uptake and glycolysis

Nutrition

Volumn 22, Issue 6, 2006, Pages 672-678

  Swagell, Christopher Dean ^a   Morris, Charles Phillip ^a   Henly, Debra Claire ^b,c  

^a QUEENSLAND UNIVERSITY OF TECHNOLOGY   (Australia)

^b BOND UNIVERSITY   (Australia)

^c UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Fatty acid signaling; Fatty acids; Glucokinase; Glycolysis; Insulin; Primary rat hepatocytes

Indexed keywords

DOCOSAHEXAENOIC ACID; FATTY ACID; GLUCOKINASE; GLUCOSE; ICOSAPENTAENOIC ACID; INSULIN; LACTIC ACID; LINOLEIC ACID; OLEIC ACID; PALMITIC ACID; PYRUVIC ACID;

ANIMAL CELL; ARTICLE; BIOACCUMULATION; CELL CULTURE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME INHIBITION; ENZYME LOCALIZATION; GLUCOSE METABOLISM; GLUCOSE TRANSPORT; GLYCOLYSIS; IN VITRO STUDY; INHIBITION KINETICS; LIVER CELL; LIVER FUNCTION; LIVER METABOLISM; NONHUMAN; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RAT;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; FATTY ACIDS; GLUCOKINASE; GLUCOSE; GLYCOLYSIS; HEPATOCYTES; INSULIN; LIVER; MALE; PHOSPHORYLATION; RATS; RATS, WISTAR; SPECTROPHOTOMETRY;

ANIMALIA;

EID: 33646432007     PISSN: 08999007     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nut.2006.03.005     Document Type: Article

References (43)

1. Mann J.I. Diet and risk of coronary heart disease and type 2 diabetes. Lancet 360 (2002) 783-789
2. Massaro M., Carluccio M.A., and De Caterina R. Direct vascular antiatherogenic effects of oleic acid. a clue to the cardioprotective effects of the Mediterranean diet. Cardiologia 44 (1999) 507-513
3. Simopoulos A.P. Essential fatty acids in health and chronic disease. Am J Clin Nutr 70 (1999) 560S-9
4. Stark A.H., and Madar Z. Olive oil as a functional food. epidemiology and nutritional approaches. Nutr Rev 60 (2002) 170-176
5. Foretz M., Guichard C., Ferre P., and Foufelle F. Sterol regulatory element binding protein-1c is a major mediator of insulin action on the hepatic expression of glucokinase and lipogenesis-related genes. Proc Natl Acad Sci USA 96 (1999) 12737-12742
6. Dentin R., Benhamed F., Pegorier J.P., Foufelle F., Viollet B., Vaulont S., et al. Polyunsaturated fatty acids suppress glycolytic and lipogenic genes through the inhibition of ChREBP nuclear protein translocation. J Clin Invest 115 (2005) 2843-2854
7. Xu J., Teran-Garcia M., Park J.H., Nakamura M.T., and Clarke S.D. Polyunsaturated fatty acids suppress hepatic sterol regulatory element-binding protein-1 expression by accelerating transcript decay. J Biol Chem 276 (2001) 9800-9807
8. Yoshikawa T., Shimano H., Yahagi N., Ide T., Amemiya-Kudo M., Matsuzaka T., et al. Polyunsaturated fatty acids suppress sterol regulatory element-binding protein 1c promoter activity by inhibition of liver X receptor (LXR) binding to LXR response elements. J Biol Chem 277 (2002) 1705-1711
9. Worgall T.S., Sturley S.L., Seo T., Osborne T.F., and Deckelbaum R.J. Polyunsaturated fatty acids decrease expression of promoters with sterol regulatory elements by decreasing levels of mature sterol regulatory element-binding protein. J Biol Chem 273 (1998) 25537-25540
10. Ou J., Tu H., Shan B., Luk A., DeBose-Boyd R.A., Bashmakov Y., et al. Unsaturated fatty acids inhibit transcription of the sterol regulatory element-binding protein-1c (SREBP-1c) gene by antagonizing ligand-dependent activation of the LXR. Proc Natl Acad Sci USA 98 (2001) 6027-6032
11. Nakatani T., Kim H.J., Kaburagi Y., Yasuda K., and Ezaki O. A low fish oil inhibits SREBP-1 proteolytic cascade, while a high-fish-oil feeding decreases SREBP-1 mRNA in mice liver. relationship to anti-obesity. J Lipid Res 44 (2003) 369-379
12. Hannah V.C., Ou J., Luong A., Goldstein J.L., and Brown M.S. Unsaturated fatty acids down-regulate srebp isoforms 1a and 1c by two mechanisms in HEK-293 cells. J Biol Chem 276 (2001) 4365-4372
13. Desvergne B., and Wahli W. Peroxisome proliferator-activated receptors. nuclear control of metabolism. Endocr Rev 20 (1999) 649-688
14. Van Schaftingen E., Detheux M., and Veiga da Cunha M. Short-term control of glucokinase activity. role of a regulatory protein. FASEB J 8 (1994) 414-419
15. Ferre T., Riu E., Bosch F., and Valera A. Evidence from transgenic mice that glucokinase is rate limiting for glucose utilization in the liver. FASEB J 10 (1996) 1213-1218
16. Prip-Buus C., Perdereau D., Foufelle F., Maury J., Ferre P., and Girard J. Induction of fatty-acid-synthase gene expression by glucose in primary culture of rat hepatocytes. Dependency upon glucokinase activity. Eur J Biochem 230 (1995) 309-319
17. Agius L. The physiological role of glucokinase binding and translocation in hepatocytes. Adv Enzyme Regul 38 (1998) 303-331
18. Wilson J.E. Hexokinases. Rev Physiol Biochem Pharmacol 126 (1995) 65-198
19. Agius L., and Peak M. Intracellular binding of glucokinase in hepatocytes and translocation by glucose, fructose and insulin. Biochem J 296 pt 3 (1993) 785-796
20. Roth U., Jungermann K., and Kietzmann T. Activation of glucokinase gene expression by hepatic nuclear factor 4alpha in primary hepatocytes. Biochem J 365 (2002) 223-228
21. Lannoy V.J., Decaux J.F., Pierreux C.E., Lemaigre F.P., and Rousseau G.G. Liver glucokinase gene expression is controlled by the onecut transcription factor hepatocyte nuclear factor-6. Diabetologia 45 (2002) 1136-1141
22. Iynedjian P.B., Jotterand D., Nouspikel T., Asfari M., and Pilot P.R. Transcriptional induction of glucokinase gene by insulin in cultured liver cells and its repression by the glucagon-cAMP system. J Biol Chem 264 (1989) 21824-21829
23. Xu J., Nakamura M.T., Cho H.P., and Clarke S.D. Sterol regulatory element binding protein-1 expression is suppressed by dietary polyunsaturated fatty acids. A mechanism for the coordinate suppression of lipogenic genes by polyunsaturated fats. J Biol Chem 274 (1999) 23577-23589
24. Berry M.E., and Barritt A. Isolated hepatocytes. preparation, properties and application (1991), Elsevier, Amsterdam
25. Berry M.N., and Friend D.S. High-yield preparation of isolated rat liver parenchymal cells. a biochemical and fine structural study. J Cell Biol 43 (1969) 506-520
26. Bergmeyer H.B.J., and Grassl M. Methods in enzymatic analysis. 3 ed (1983), Verlag Chemie GmbH, Weinheim
27. Clark D.G., Rognstad R., and Katz J. Isotopic evidence for futile cycles in liver cells. Biochem Biophys Res Commun 54 (1973) 1141-1148
28. Berry M.N., Phillips J.W., Henly D.C., and Clark D.G. Effects of fatty acid oxidation on glucose utilization by isolated hepatocytes. FEBS Lett 319 (1993) 26-30
29. Quandt K., Frech K., Karas H., Wingender E., and Werner T. MatInd and MatInspector. new fast and versatile tools for detection of consensus matches in nucleotide sequence data. Nucleic Acids Res 23 (1995) 4878-4884
30. Iynedjian P.B., Gjinovci A., and Renold A.E. Stimulation by insulin of glucokinase gene transcription in liver of diabetic rats. J Biol Chem 263 (1988) 740-744
31. Koyama K., Chen G., Lee Y., and Unger R.H. Tissue triglycerides, insulin resistance, and insulin production. implications for hyperinsulinemia of obesity. Am J Physiol 273 (1997) E708-E713
32. Pawar A., Xu J., Jerks E., Mangelsdorf D.J., and Jump D.B. Fatty acid regulation of liver X receptors (LXR) and peroxisome proliferator-activated receptor alpha (PPARalpha) in HEK293 cells. J Biol Chem 277 (2002) 39243-39250
33. Forman B.M., Chen J., and Evans R.M. Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta. Proc Natl Acad Sci USA 94 (1997) 4312-4317
34. Malewiak M.I., Griglio S., and Le Liepvre X. Relationship between lipogenesis, ketogenesis, and malonyl-CoA content in isolated hepatocytes from the obese Zucker rat adapted to a high-fat diet. Metabolism 34 (1985) 604-611
35. Wilson M.D., Hays R.D., and Clarke S.D. Inhibition of liver lipogenesis by dietary polyunsaturated fat in severely diabetic rats. J Nutr 116 (1986) 1511-1518
36. Minamoto S., Kanazawa K., Ashida H., and Natake M. Effect of orally administered 9-oxononanoic acid on lipogenesis in rat liver. Biochim Biophys Acta 958 (1988) 199-204
37. Wilson M.D., Blake W.L., Salati L.M., and Clarke S.D. Potency of polyunsaturated and saturated fats as short-term inhibitors of hepatic lipogenesis in rats. J Nutr 120 (1990) 544-552
38. Henly D.C., Chauvet M.C., and Phillips J.W. Hepatic glucose cycling does not contribute to the development of hyperglycemia in Zucker diabetic fatty rats. Diabetes 48 (1999) 342-346
39. Marchut E., Guminska M., and Kedryna T. The inhibitory effect of various fatty acids on aerobic glycolysis in Ehrlich ascites tumour cells. Acta Biochim Pol 33 (1986) 7-16
40. Chatham J., Gilbert H.F., and Radda G.K. Inhibition of glucose phosphorylation by fatty acids in the perfused rat heart. FEBS Lett 238 (1988) 445-449
41. Boden G., Chen X., Ruiz J., White J.V., and Rossetti L. Mechanisms of fatty acid-induced inhibition of glucose uptake. J Clin Invest 93 (1994) 2438-2446
42. Sidossis L.S., Stuart C.A., Shulman G.I., Lopaschuk G.D., and Wolfe R.R. Glucose plus insulin regulate fat oxidation by controlling the rate of fatty acid entry into the mitochondria. J Clin Invest 98 (1996) 2244-2250
43. Power G.W., and Newsholme E.A. Dietary fatty acids influence the activity and metabolic control of mitochondrial carnitine palmitoyltransferase I in rat heart and skeletal muscle. J Nutr 127 (1997) 2142-2150