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Volumn 98, Issue 10, 1996, Pages 2244-2250

Glucose plus insulin regulate fat oxidation by controlling the rate of fatty acid entry into the mitochondria

Author keywords

carnitine palmitoyltransferase; diabetes; malonyl coenzyme A; medium chain fatty acids; obesity

Indexed keywords

ACYLCARNITINE; CARNITINE PALMITOYLTRANSFERASE; FATTY ACID; GLUCOSE; HEPARIN; INSULIN; MALONYL COENZYME A; OCTANOIC ACID; OLEIC ACID;

EID: 0029852840     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI119034     Document Type: Article
Times cited : (205)

References (28)
  • 1
    • 50549202600 scopus 로고
    • The glucose-fatty acid cycle: Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus
    • Randle, P.J., P.B. Garland, C.N. Hales, and E.A. Newsholme. 1963. The glucose-fatty acid cycle: its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus. Lancet. 1:785-789.
    • (1963) Lancet , vol.1 , pp. 785-789
    • Randle, P.J.1    Garland, P.B.2    Hales, C.N.3    Newsholme, E.A.4
  • 3
    • 0028342686 scopus 로고
    • Mechanisms of fatty acid-induced inhibition of glucose uptake
    • Boden, G., X. Chen, J. Ruiz, J.V. White, and L. Rossetti. 1994. Mechanisms of fatty acid-induced inhibition of glucose uptake. J. Clin. Invest. 93: 2438-2446.
    • (1994) J. Clin. Invest. , vol.93 , pp. 2438-2446
    • Boden, G.1    Chen, X.2    Ruiz, J.3    White, J.V.4    Rossetti, L.5
  • 6
    • 0023908033 scopus 로고
    • Effect of elevated free fatty acids on glucose oxidation in normal humans
    • Wolfe, B.M., S. Klein, E.J. Peters, B.F. Schmidt, and R.R. Wolfe. 1988. Effect of elevated free fatty acids on glucose oxidation in normal humans. Metab. Clin. Exp. 37:323-329.
    • (1988) Metab. Clin. Exp. , vol.37 , pp. 323-329
    • Wolfe, B.M.1    Klein, S.2    Peters, E.J.3    Schmidt, B.F.4    Wolfe, R.R.5
  • 7
    • 0025835909 scopus 로고
    • Effect of free fatty acids on glucose uptake and nonoxidative glycolysis across human forearm tissues in the basal state and during insulin stimulation
    • Yki-Yärvinen, H., I. Puhakainen, and V.A. Koivisto. 1991. Effect of free fatty acids on glucose uptake and nonoxidative glycolysis across human forearm tissues in the basal state and during insulin stimulation. J. Clin. Endocrinol. & Metab. 72:1268-1277.
    • (1991) J. Clin. Endocrinol. & Metab. , vol.72 , pp. 1268-1277
    • Yki-Yärvinen, H.1    Puhakainen, I.2    Koivisto, V.A.3
  • 8
    • 0023154984 scopus 로고
    • Lipolytic response to glucose infusion in human subjects
    • Wolfe, R.R., and E.J. Peters. 1987. Lipolytic response to glucose infusion in human subjects. Am. J. Physiol. 252:E218-E223.
    • (1987) Am. J. Physiol. , vol.252
    • Wolfe, R.R.1    Peters, E.J.2
  • 9
    • 0029991872 scopus 로고    scopus 로고
    • Glucose and insulin-induced inhibition of fatty acid oxidation: The glucose-fatty acid cycle reversed
    • Sidossis, L.S., and R.R. Wolfe. 1996. Glucose and insulin-induced inhibition of fatty acid oxidation: the glucose-fatty acid cycle reversed. Am. J. Physiol. 270:E733-E738.
    • (1996) Am. J. Physiol. , vol.270
    • Sidossis, L.S.1    Wolfe, R.R.2
  • 10
    • 0017738601 scopus 로고
    • A possible role for malonyl-CoA in the regulation of hepatic acid oxidation and ketogenesis
    • McGarry, J.D., G.P. Mannaerts, and D.W. Foster. 1977. A possible role for malonyl-CoA in the regulation of hepatic acid oxidation and ketogenesis. J. Clin. Invest. 60:265-270.
    • (1977) J. Clin. Invest. , vol.60 , pp. 265-270
    • McGarry, J.D.1    Mannaerts, G.P.2    Foster, D.W.3
  • 11
    • 70449298674 scopus 로고
    • Action of carnitine on long chain fatty acid oxidation by liver
    • Fritz, I.B. 1959. Action of carnitine on long chain fatty acid oxidation by liver. Am. J. Physiol. 197:297-304.
    • (1959) Am. J. Physiol. , vol.197 , pp. 297-304
    • Fritz, I.B.1
  • 12
    • 0020624753 scopus 로고
    • Observations on the affinity for carnitine, and malonyl-CoA sensitivity, of carnitine palmitoyltransferase I in animal and human tissues
    • McGarry, J.D., S.E. Milles, C.S. Long, and D.W. Foster. 1983. Observations on the affinity for carnitine, and malonyl-CoA sensitivity, of carnitine palmitoyltransferase I in animal and human tissues. Biochem. J. 214:21-28.
    • (1983) Biochem. J. , vol.214 , pp. 21-28
    • McGarry, J.D.1    Milles, S.E.2    Long, C.S.3    Foster, D.W.4
  • 13
    • 0024503204 scopus 로고
    • Regulation of ketogenesis and the renaissance of carnitine palmitoyltransferase
    • McGarry, J.D., K.F. Woeltje, M. Kuwajima, and D.W. Foster. 1989. Regulation of ketogenesis and the renaissance of carnitine palmitoyltransferase. Diabetes Metab. Rev. 5:271-284.
    • (1989) Diabetes Metab. Rev. , vol.5 , pp. 271-284
    • McGarry, J.D.1    Woeltje, K.F.2    Kuwajima, M.3    Foster, D.W.4
  • 14
    • 0015239151 scopus 로고
    • The regulation of ketogenesis from octanoic acid. The role of the tricarboxylic acid cycle and fatty acid synthesis
    • McGarry, J.D., and D.W. Foster. 1971. The regulation of ketogenesis from octanoic acid. The role of the tricarboxylic acid cycle and fatty acid synthesis. J. Biol. Chem. 246:1149-1159.
    • (1971) J. Biol. Chem. , vol.246 , pp. 1149-1159
    • McGarry, J.D.1    Foster, D.W.2
  • 17
    • 0028809650 scopus 로고
    • A new correction factor for use in tracer estimations of plasma fatty acid oxidation
    • Sidossis, L.S., A.R. Coggan, A. Gastaldelli, and R.R. Wolfe. 1995. A new correction factor for use in tracer estimations of plasma fatty acid oxidation. Am. J. Physiol. 269:E649-E656.
    • (1995) Am. J. Physiol. , vol.269
    • Sidossis, L.S.1    Coggan, A.R.2    Gastaldelli, A.3    Wolfe, R.R.4
  • 18
    • 0028895785 scopus 로고
    • Pathway of free fatty acid oxidation in human subjects. Implications for tracer studies
    • Sidossis, L.S., A.R. Coggan, A. Gastaldelli, and R.R. Wolfe. 1995. Pathway of free fatty acid oxidation in human subjects. Implications for tracer studies. J. Clin. Invest. 95:278-284.
    • (1995) J. Clin. Invest. , vol.95 , pp. 278-284
    • Sidossis, L.S.1    Coggan, A.R.2    Gastaldelli, A.3    Wolfe, R.R.4
  • 19
    • 0026007729 scopus 로고
    • Effect of increased plasma free fatty acid concentrations on muscle metabolism in exercising men
    • Hargreaves, M., B. Kiens, and E.A. Richter. 1991. Effect of increased plasma free fatty acid concentrations on muscle metabolism in exercising men. J. Appl. Physiol. 70:194-201.
    • (1991) J. Appl. Physiol. , vol.70 , pp. 194-201
    • Hargreaves, M.1    Kiens, B.2    Richter, E.A.3
  • 21
    • 0017824474 scopus 로고
    • Coenxyme a and carnitine distribution in normal and ischemic hearts
    • Idell-Wenger, J.A., L.W. Grotyohann, and J.R. Neely. 1978. Coenxyme A and carnitine distribution in normal and ischemic hearts. J. Biol. Chem. 253: 4310-4318.
    • (1978) J. Biol. Chem. , vol.253 , pp. 4310-4318
    • Idell-Wenger, J.A.1    Grotyohann, L.W.2    Neely, J.R.3
  • 22
    • 0024210550 scopus 로고
    • Determination of short-chain coenzyme a compounds by reversed-phase high-performance liquid chromatography
    • King, M.T., P.D. Reiss, and N.W. Cornell. 1988. Determination of short-chain coenzyme A compounds by reversed-phase high-performance liquid chromatography. Methods Enzymol. 166:70-79.
    • (1988) Methods Enzymol. , vol.166 , pp. 70-79
    • King, M.T.1    Reiss, P.D.2    Cornell, N.W.3
  • 23
    • 0020576146 scopus 로고
    • Calculation of substrate oxidation rates in vivo from gaseous exchange
    • Frayn, K.H. 1983. Calculation of substrate oxidation rates in vivo from gaseous exchange. J. Appl. Physiol. 55:628-634.
    • (1983) J. Appl. Physiol. , vol.55 , pp. 628-634
    • Frayn, K.H.1
  • 24
    • 0016163592 scopus 로고
    • The metabolism of (-)-octanoylcarnitine in perfused livers from fed and fasted rats: Evidence for a possible regulatory role of carnitine acyltransferase in the control of ketogenesis
    • McGarry, J.D., and D.W. Foster. 1974. The metabolism of (-)-octanoylcarnitine in perfused livers from fed and fasted rats: evidence for a possible regulatory role of carnitine acyltransferase in the control of ketogenesis. J. Biol. Chem. 249:7984-7990.
    • (1974) J. Biol. Chem. , vol.249 , pp. 7984-7990
    • McGarry, J.D.1    Foster, D.W.2
  • 25
    • 0024795323 scopus 로고
    • Regulation of fatty acid synthesis via phosphorylation of acetyl-CoA carboxylase
    • Hardie, D.G. 1989. Regulation of fatty acid synthesis via phosphorylation of acetyl-CoA carboxylase. Prog. Lipid Res. 28:117-146.
    • (1989) Prog. Lipid Res. , vol.28 , pp. 117-146
    • Hardie, D.G.1
  • 26
  • 27
    • 0027453493 scopus 로고
    • Acetyl-CoA carboxylase regulation of fatty acid oxidation in the heart
    • Saddik, M., J. Gamble, L.A. Witters, and G.D. Lopaschuk. 1993. Acetyl-CoA carboxylase regulation of fatty acid oxidation in the heart. J. Biol. Chem. 268:25836-25845.
    • (1993) J. Biol. Chem. , vol.268 , pp. 25836-25845
    • Saddik, M.1    Gamble, J.2    Witters, L.A.3    Lopaschuk, G.D.4
  • 28
    • 0025248418 scopus 로고
    • Indirect calorimetry: Methodological and interpretative problems
    • Simonson, D.C., and R.A. DeFronzo. 1990. Indirect calorimetry: methodological and interpretative problems. Am. J. Physiol. 258:E399-E412.
    • (1990) Am. J. Physiol. , vol.258
    • Simonson, D.C.1    DeFronzo, R.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.