Effect of prior hyperglycemia on IL-6 responses to exercise in children with type 1 diabetes

American Journal of Physiology - Endocrinology and Metabolism

Volumn 290, Issue 5, 2006, Pages

  Galassetti, P R ^a,b   Iwanaga, K ^a   Pontello, A M ^a   Zaldivar, F P ^a   Flores, R L ^a   Larson, J K ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Exercise adaptation; Glycemia; Inflammatory cytokines; Insulin

Indexed keywords

ADRENALIN; GLUCAGON; GLUCOSE; GROWTH HORMONE; HYDROCORTISONE; INTERLEUKIN 6; SOMATOMEDIN BINDING PROTEIN;

ADOLESCENT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE EXACERBATION; EXERCISE TOLERANCE; FEMALE; GLUCOSE BLOOD LEVEL; HUMAN; HYPERGLYCEMIA; INSULIN DEPENDENT DIABETES MELLITUS; MALE; ORAL GLUCOSE TOLERANCE TEST; OXYGEN CONSUMPTION; PRIORITY JOURNAL; SCHOOL CHILD; STEADY STATE;

ADOLESCENT; BLOOD GLUCOSE; CHILD; DIABETES MELLITUS, TYPE 1; EPINEPHRINE; EXERCISE; EXERCISE TEST; FEMALE; GLUCAGON; GLUCOSE CLAMP TECHNIQUE; GROWTH SUBSTANCES; HUMANS; HYDROCORTISONE; HYPERGLYCEMIA; INSULIN; INTERLEUKIN-6; MALE; OXYGEN CONSUMPTION;

EID: 33646390080     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00445.2005     Document Type: Article

References (37)

1. Berman M. Pattern of physical activity in children. Am J Human Biol 10: 289-297, 1998.
2. Brenner I, Shek PN, ZamecniK J, and Shephard RJ. Stress hormones and the immunological responses to heat and exercise. Int J Sports Med 19: 130-143, 1998.
3. Brix-Christensen V, Gjedsted J, Andersen SK, Vestergaard C, Nielsen J, Rix T, Nyboe R, Andersen NT, Larsson A, Schmitz O, and Tonnesen E. Inflammatory response during hyperglycemia and hyperinsulinemia in a porcine endotoxemic model: the contribution of essential organs. Acta Anaesthesiol Scand 49: 991-998, 2005.
4. Cooper DM, Barstow T, Bergner A, and Lee WNP. Blood glucose turnover during high- and low-intensity exercise. Am J Physiol Endocrinol Metab 257: E405-E412, 1989.
5. Cooper DM, Nemet D, and Galassetti P. Exercise, stress, and inflammation in the growing child: from the bench to the playground. Curr Opin Pediatr 16: 286-292, 2004.
6. Cooper DM, Weiler-Ravell D, Whipp BJ, and Wasserman K. Aerobic parameters of exercise as a function of body size during growth in children. J Appl Physiol 56: 628-634, 1984.
7. Davis SN, Galassetti P, Wasserman DH, and Tate D. Effect of gender on neuroendocrine and metabolic counterregulatory responses to exercise in normal man. J Clin Endocrinol Metab 85: 224-230, 2000.
8. Davis SN, Galassetti P, Wasserman DH, and Tate D. Effects of antecedent hypoglycemia on subsequent counterregulatory responses to exercise. Diabetes 49: 73-81, 2000.
9. Davis SN, Shavers C, Mosqueda-Garcia R, and Costa F. Effects of differing antecedent hypoglycemia on subsequent counterregulation in normal humans. Diabetes 46: 1328-1335, 1997.
10. Devaraj S and Jialal I. Alpha tocopherol supplementation decreases serum C-reactive protein and monocyte interleukin-6 levels in normal volunteers and type 2 diabetic patients. Free Radic Biol Med 29: 790-792, 2000.
11. Devaraj S, Venugopal SK, Singh U, and Jialal I. Hyperglycemia induces monocytic release of interleukin-6 via induction of protein kinase c-α and -β. Diabetes 54: 85-91, 2005.
12. Devlin J, Barlow J, and Horton E. Whole body and regional fuel metabolism during early post-exercise recovery. Am J Physiol Endocrinol Metab 256: E167-E172, 1989.
13. Erbagci AB, Tarakcioglu M, Coskun Y, Sivasli E, and Sibel NE. Mediators of inflammation in children with type I diabetes mellitus: cytokines in type I diabetic children. Clin Biochem 34: 645-650, 2001.
14. Esposito K, Nappo F, Marfella R, Giugliano G, Giugliano F, Ciotola M, Quagliaro L, Ceriello A, and Giugliano D. Inflammatory cytokine concentrations are acutely increased by hyperglycemia in humans: role of oxidative stress. Circulation 106: 2067-2072, 2002.
15. Fishel MA, Watson GS, Montine TJ, Wang Q, Green PS, Kulstad JJ, Cook DG, Peskind ER, Baker LD, Goldgaber D, Nie W, Asthana S, Plymate SR, Schwartz MW, and Craft S. Hyperinsulinemia provokes synchronous increases in central inflammation and β-amyloid in normal adults. Arch Neurol In press.
16. Galassetti P, Tate D, Neill RA, Morrey S, Wasserman DH, and Davis SN. Effect of antecedent hypoglycemia on counterregulatory responses to subsequent euglycemic exercise in Type 1 diabetes. Diabetes 52: 1761-1769, 2003.
17. Galassetti P, Iwanaga K, Crisostomo M, Zaldivar F, Larson J, and Pescatello AM. Inflammatory cytokine, growth factor and counterregulatory responses to exercise in children with Type 1 diabetes and healthy controls. Pediatric Diabetes In press.
18. Galassetti P, Tate D, Neill RA, Morrey S, Wasserman DH, and Davis SN. Effect of sex on counterregulatory responses to exercise after antecedent hypoglycemia in type 1 diabetes. Am J Physiol Endocrinol Metab 287: E16-E24, 2004.
19. Galassetti P, Tate D, Neill RA, Richardson A, Leu SY, and Davis SN. Effect of differing antecedent hypoglycemia on counterregulatory responses to exercise in type 1 diabetes. Am J Physiol Endocrinol Metab [ePub Jan. 10, 2006; doi:10.1152/ajpendo.00244.2005].
20. Harrell JS, McMurray RG, Baggett CD, Pennell ML, Pearce PF, and Bangdiwala SI. Energy costs of physical activities in children and adolescents. Med Sci Sports Exerc 37: 329-336, 2005.
21. Holt RI, Simpson HL, and Sonksen PH. The role of the growth hormone-insulin-like growth factor axis in glucose homeostasis. Diabet Med 20: 3-15, 2003.
22. Ishihara K and Hirano T. IL-6 in autoimmune disease and chronic inflammatory proliferative disease. Cytokine Growth Factor Rev 13: 357-368, 2002.
23. Jain SK, Kannan K, Lim G, Matthews-Greer J, McVie R, and Bocchini JA Jr. Elevated blood interleukin-6 levels in hyperketonemic type 1 diabetic patients and secretion by acetoacetate-treated cultured U937 monocytes. Diabetes Care 26: 2139-2143, 2003.
24. Marliss EB, Simantirakis E, Miles PD, Purdon C, Gougeon R, Field CJ, Halter JB, and Vranic M. Glucoregulatory and hormonal responses to repeated bouts of intense exercise in normal male subjects. J Appl Physiol 71: 924-933, 1991.
25. Mohamed-Ali V, Armstrong L, Clarke D, Bolton CH, and Pinkney JH. Evidence for the regulation of levels of plasma adhesion molecules by pro-inflammatory cytokines and their soluble receptors in type 1 diabetes. J Intern Med 250: 415-421, 2001.
26. Nemet D, Oh Y, Kim HS, Hill MA, and Cooper DM. The effect of intense exercise on inflammatory cytokines and growth mediators in adolescent boys. Pediatrics 110: 681-689, 2002.
27. Nybo L, Nielsen B, Pedersen BK, Moller K, and Secher NH. Interleukin-6 release from the human brain during prolonged exercise. J Physiol 542: 991-995, 2002.
28. Pedersen BK and Febbraio M. Muscle-derived interleukin-6 -a possible link between skeletal muscle, adipose tissue, liver, and brain. Brain Behav Immun 19: 371-376, 2005.
29. Petersen AC, Crockett L, Richards M, and Boxer A. A self-report measure of pubertal status: reliability, validity and initial norms. J Youth Adolesc 17: 117-133, 1988.
30. Rhind SG, Castellani JW, Brenner IK, Shephard RJ, Zamecni KJ, Montain SJ, Young AJ, and Shek PN. Intracellular monocyte and serum cytokine expression is modulated by exhausting exercise and cold exposure. Am J Physiol Regul Integr Comp Physiol 281: R66-R75, 2001.
31. Stentz FB, Umpierrez GE, Cuervo R, and Kitabchi AE. Proinflammatory cytokines, markers of cardiovascular risks, oxidative stress, and lipid peroxidation in patients with hyperglycemic crises. Diabetes 53: 2079-2086, 2004.
32. Targher G, Zenari L, Bertolini L, Muggeo M, and Zoppini G. Elevated levels of interleukin-6 in young adults with type 1 diabetes without clinical evidence of microvascular and macrovascular complications. Diabetes Care 24: 956-957, 2001.
33. Testa R, Olivieri F, Bonfigli AR, Sirolla C, Boemi M, Marchegiani F, Marra M, Cenerelli S, Antonicelli R, Dolci A, Paolisso G, and Franceschi C. Interleukin-6-174 G>C polymorphism affects the association between IL-6 plasma levels and insulin resistance in type 2 diabetic patients. Diabetes Res Clin Pract In press.
34. Tirakitsoontorn P, Nussbaum E, Moser C, Hill M, and Cooper DM. Fitness, acute exercise, and anabolic and catabolic mediators in cystic fibrosis. Am J Respir Crit Care Med 164: 1432-1437, 2001.
35. Trayhurn P and Wood IS. Adipokines: inflammation and the pleiotropic role of white adipose tissue. Br J Nutr 92: 347-355, 2004.
36. Wigal SB, Nemet D, Swanson JM, Regino R, Trampush J, Ziegler MG, and Cooper DM. Catecholamine response to exercise in children with attention deficit hyperactivity disorder. Pediatr Res 53: 756-761, 2003.
37. Yamagishi S and Imaizumi T. Diabetic vascular complications: pathophysiology, biochemical basis and potential therapeutic strategy. Curr Pharm Des 11: 2279-2299, 2005.