A continuous dietary supply of free calcium formate negatively affects the parietal cell population and gastric RNA expression for H+/K +-ATPase in weaning pigs

Journal of Nutrition

Volumn 136, Issue 5, 2006, Pages 1229-1235

  Bosi, Paolo ^a   Mazzoni, Maurizio ^a   De Filippi, Sara ^a   Trevisi, Paolo ^a   Casini, Luisa ^a   Petrosino, Gregorio ^b   Lalatta Costerbosa, Giovanna ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b CATHOLIC UNIVERSITY   (Italy)

Author keywords

Acidifiers; H+ K+ ATPase; Parietal cells; Pigs; Weaning

Indexed keywords

CALCIUM DERIVATIVE; CALCIUM FORMATE; CHROMOGRANIN A; HISTAMINE; HYDROCHLORIC ACID; HYDROGEN POTASSIUM ADENOSINE TRIPHOSPHATASE; SOMATOSTATIN; UNCLASSIFIED DRUG;

ACID SECRETION; ANIMAL TISSUE; CONFERENCE PAPER; DIET SUPPLEMENTATION; DIET THERAPY; ENTEROCHROMAFFIN CELL; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; INTESTINE VILLUS; NONHUMAN; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SENSITIVITY ANALYSIS; STOMACH PARIETAL CELL; STOMACH PROTECTION; SWINE;

ANIMALIA; SUS SCROFA;

EID: 33646389522     PISSN: 00223166     EISSN: 15416100     Source Type: Journal    
DOI: 10.1093/jn/136.5.1229     Document Type: Conference Paper

References (47)

1. Cranwell PD, Noakes DE, Hill KJ. Gastric secretion and fermentation in the suckling pig. Br J Nutr. 1976;36:71-86.
2. Tudor EM, Schofield GC, Titchen DA. Structural and functional development of the gastric parietal cell population in the newborn pig. Ann Rech Vet. 1977;8:450-9.
3. Cranwell PD. The development of acid and pepsin (EC 3.4.23.1) secretory capacity in the pig; the effects of age and weaning. 1. Studies in anaesthetized pigs. Br J Nutr. 1985;54:305-20.
4. Partanen KH, Mroz Z. Organic acids for performance enhancement in pig diets. Nutr Res Rev. 1999;12:117-45.
5. Tsiloyiannis VK, Kyriakis SC, Vlemmas J, Sarris K. The effect of organic acids on the control of porcine post-weaning diarrhoea. Res Vet Sci. 2001;70:287-93.
6. Brunser O, Araya M, Espinoza J, Guesry PR, Secretin MC, Pacheco I. Effect of an acidified milk on diarrhoea and the carrier state in infants of low socioeconomic stratum. Acta Paediatr Scand. 1989;78:259-64.
7. Mehall JR, Northrop R, Saltzman DA, Jackson RJ, Smith SD. Acidification of formula reduces bacterial translocation and gut colonization in a neonatal rabbit model. J Pediatr Surg. 2001;36:56-62.
8. Heyland DK, Cook DJ, Schoenfeld PS, Frietag A, Varon J, Wood G. The effect of acidified enteral feeds on gastric colonization in critically ill patients: results of a multicenter randomized trial. Canadian Critical Care Trials Group. Crit Care Med. 1999;27:2399-406.
9. Hanzlik RP, Fowler SC, Fisher DH. Relative bioavailability of calcium from calcium formate, calcium citrate, and calcium carbonate. J Pharmacol Exp Ther. 2005;313:1217-22.
10. Hanzlik RP, Fowler SC, Eells JT. Absorption and elimination of formate following oral administration of calcium formate in female human subjects. Drug Metab Dispos. 2005;33:282-6.
11. Pettitt JM, Humphris DC, Barrett SP, Toh BH, van Driel IR, Gleeson PA. Fast freeze-fixation/freeze-substitution reveals the secretory membranes of the gastric parietal cell as a network of helically coiled tubule. A new model for parietal cell transformation. J Cell Sci. 1995;108:1127-41.
12. (+)-ATPase gene expression in canine gastric parietal cells. Ann N Y Acad Sci. 1989;574:159-64.
13. Beinborn M, Giebel J, Linck M, Cetin Y, Schwenk M, Sewing KF. Isolation, identification and quantitative evaluation of specific cell types from the mammalian gastric mucosa. Cell Tissue Res. 1993;274:229-40.
14. Schubert ML. Gastric secretion. Curr Opin Gastroenterol. 2003;19:519-25.
15. Tzaneva MA. Electron microscopic immunohistochemical investigation of chromogranin A in endocrine cells in human oxyntic gastric mucosa. Acta Histochem. 2001;103:179-94.
16. Portela-Gomes GM, Stridsberg M. Chromogranin A in the human gastrointestinal tract: an immunocytochemical study with region-specific antibodies. J Histochem Cytochem. 2002;50:1487-92.
17. Kamoshida S, Saito E, Fukuda S, Kato K, Iwasaki A, Arakawa Y. Anatomical location of enterochromaffin-like (ECL) cells, parietal cells, and chief cells in the stomach demonstrated by immunocytochemistry and electron microscopy. J Gastroenterol. 1999;34:315-20.
18. Hakanson R, Böttcher G, Ekblad E, Panula P, Simonsson M, Dohlsten M, Hallbergh T, Sundler F. Histamine in endocrine cells in the stomach. A survey of several species using a panel of histamine antibodies. Histochemistry. 1986;86:5-17.
19. Lindström E, Chen D, Norlén P, Andersson K, Hakanson R. Control of gastric acid secretion: the gastrin-ECL cell-parietal cell axis. Comp Biochem Physiol A Mol Integr Physiol. 2001;128:505-14.
20. Walsh JH, Richardson CT, Fortran JS. pH dependence of acid secretion and gastrin release in normal and ulcer subjects. J Clin Invest. 1975;55:462-8.
21. Fahrenkrug J, Schaffalitzky de Muckadell OB, Hornum I, Rehfeld JF. The mechanism of hypergastrinemia in achlorhydria. Effect of food, acid, and calcitonin on serum gastrin concentrations and component pattern in pernicious anemia, with correlation to endogenous secretin concentrations in plasma. Gastroenterology. 1976;71:33-7.
22. Konturek SJ, Rayford PL, Thompson JC. Effect of pH of gastric and intestinal meals on gastric acid and plasma gastrin and secretin responses in the dog. Am J Physiol. 1977;233:E537-43.
23. Schmidt WE, Schmitz F. Genetic dissection of the secretory machinery in the stomach. Gastroenterology. 2004;126:606-9.
24. Osek J. Prevalence of virulence factors of Escherichia coli strains isolated from diarrheic and healthy piglets after weaning. Vet Microbiol. 1999;68:209-17.
25. Van den Broeck W, Cox E, Goddeeris BM. Receptor-dependent immune responses in pigs after oral immunization with F4 fimbriae. Infect Immun. 1999;67:520-6.
26. Chiocchetti R, Grandis AM, Bombardi C, Clavenzani P, Lalatta-Costerbosa G, Lucchi ML, Furness JB. Characterisation of neurons expressing calbindin immunoreactivity in the ileum of unweaned and mature sheep. Cell Tissue Res. 2004;318:289-303.
27. Novikoff AB, Shin WY, Drucker J. Mitochondrial localization of oxidative enzymes: staining results with two tetrazolium salts. J Biophys Biochem Cytol. 1961;9:47-61.
28. McManus JFA, Mowry RW. Staining methods. Histologic and histochemical. New York: Hoeber, 1960.
29. Bustin SA. Quantification of mRNA using real-time reverse transcription PCR (RT-PCR): trends and problems. J Mol Endocrinol. 2002;29:23-39.
30. Bosi P, Gremokolini C, Trevisi P, Mazzoni M, Bonilauri P, Sarli G, Casini L. La stimulation orale par E. coli K88 comme méthode d'évaluation des performances de croissance et de l'état de santé des porcelets sevrés dans les études expérimentales d'alimentation. [Oral challenge with E. coli K88 as a tool to assess growth and health performance in feeding trials of weaned pigs]. Journées Recherche Porcine. 2004;36:125-32.
31. 3 exchanger PAT 1 and gastric H-K-ATPase in stomach parietal cells. Am J Physiol Gastrointest Liver Physiol. 2002;283:G1207-16.
32. +-ATPase and its alterations as related to acid secretion. Histochem Cell Biol. 2002;117:21-7.
33. Helander HF. The cells of the gastric mucosa. Int Rev Cytol. 1981;70:217-89.
34. Bjorkqvist M, Norlen P, Kitano M, Chen D, Zhao CM, de la Cour CD, Gagnemo-Persson C, Hakanson R. Effects of CCK2 receptor blockade on growth parameters in gastrointestinal tract and pancreas in rats. Pharmacol Toxicol. 2001;89:208-13.
35. Friis-Hansen L. Gastric functions in gastrin gene knock-out mice. Pharmacol Toxicol. 2002;91:363-7.
36. Zhao CM, Wang X, Friis-Hansen L, Waldum HL, Halgunset J, Wadstrom T, Chen D. Chronic Helicobacter pylori infection results in gastric hypoacidity and hypergastrinemia in wild-type mice but vagally induced hypersecretion in gastrin-deficient mice. Regul Pept. 2003;115:161-70.
37. Chen D, Zhao CM, Hakanson R, Samuelson LC, Rehfeld JF, Friis-Hansen L. Altered control of gastric acid secretion in gastrin-cholecystokinin double mutant mice. Gastroenterology. 2004;126:476-87.
38. Allen JP, Canty AJ, Schulz S, Humphrey PP, Emson PC, Young HM. Identification of cells expressing somatostatin receptor 2 in the gastrointestinal tract of Sstr2 knockout/lacZ knockin mice. J Comp Neurol. 2002;454:329-40.
39. Bloom SR, Mortimer CH, Thorner MO, Besser GM, Hall R, Gomez-Pan A, Roy VM, Russell RC, Coy DH, et al. Inhibition of gastrin and gastric-acid secretion by growth-hormone release-inhibiting hormone. Lancet 1974:2(7889):1106-1109.
40. Fykse V, Coy DH, Waldum HL, Sandvik AK. Somatostatin-receptor 2 (sst2)-mediated effects of endogenous somatostatin on exocrine and endocrine secretion of the rat stomach. Br J Pharmacol. 2005;144:416-21.
41. Konturek JW, Konturek SJ, Domschke W. Cholecystokinin in the control of gastric acid secretion and gastrin release in response to a meal at low and high pH in healthy subjects and duodenal ulcer patients. Scand J Gastroenterol. 1995;30:738-44.
42. Nakamura E, Kataoka T, Furutani K, Jimbo K, Aihara T, Tanaka S, Ichikawa A, Ohtsu H, Okabe S. Lack of histamine alters gastric mucosal morphology: comparison of histidine decarboxylase-deficient and mast cell-deficient mice. Am J Physiol Gastrointest Liver Physiol. 2004;287:G1053-61.
43. Chen D, Monstein HJ, Nylander AG, Zhao CM, Sundler F, Hakanson R. Acute responses of rat stomach enterochromaffinlike cells to gastrin: secretory activation and adaptation. Gastroenterology. 1994;107:18-27.
44. Chin C, Lerman J, Endo J. Acute lung injury after tracheal instillation of acidified soya-based or Enfalac formula or human breast milk in rabbits. Can J Anaesth. 1999;46:282-6.
45. Doscherholmen A, Ripley D, Chang S, Silvis SE. Influence of age and stomach function on serum vitamin B12 concentration. Scand J Gastroenterol. 1977;12:313-9.
46. 12 levels in patients with Zollinger-Ellison syndrome. Am J Med. 1998;104:422-30.
47. Zavros Y, Rieder G, Ferguson A, Samuelson LC, Merchant JL. Genetic or chemical hypochlorhydria is associated with inflammation that modulates parietal and G-cell populations in mice. Gastroenterology. 2002;122:119-33.